Gene identifier: TC003413
Genomic location: NC_007418.3:4685873..4710094
View gene expression at BeetleAtlas 
View orthologs at OrthoDB 
Gene IDAlgorithmsGene SymbolGene NameShow GO Terms
FBgn0000560OrthoFindereg
FBgn0000560
GO:0035287 - head segmentation
IMP
REVIEWED

Tribolium head patterning depends on early knirps function. In Tribolium, the inactivation of Tc-knirps activity leads to a deletion of the antennal and mandibular segments
PMID:18586236
GO:0035290 - trunk segmentation
IMP
REVIEWED

Depletion of Tc-knirps function results in mild abdominal segmentation defects
PMID:18586236
Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.
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GO:
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protein
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Authors: Cerny et al.Journal: Developmental biologyYear: 2008
Authors: Tan and PalliJournal: Insect biochemistry and molecular biologyYear: 2007
Authors: Peel et al.Journal: BMC developmental biologyYear: 2013
Authors: Bucher et al.Journal: Evolution & developmentYear: 2005
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Enter below the information to describe one phenotype.
*Gene:
dsRNA:
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Sequence of the new dsRNA:
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ng/μl
*Injected stage:
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*Affected structure:
Affected process:
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Lethalities 11 days after pupal injection: 30% (includes death as pupa, adult)
Lethalities 11 days after larval injection: 30% (includes death as larva, prepupa, pupa)
Lethalities 22 days after larval injection: 70% (includes death as larva, prepupa, pupa, adult)
pupal molt not completely molted
40%
day 11
larva lethality
30%
day 11
eclosion not fulfilled (died as pupa)
40%
day 16
adult nutritional state bad (cachectic)
10%
day 22
mature egg deposition >5 blocked number 1st lateral oviduct: number 2nd lateral oviduct:
20%
day 22
egg production: number no/almost no eggs
day 22
pupa eclosion not fulfilled (died as pupa)
20%
day 3
adult lethality
10%
day 11
embryo/egg not developed/not fertilized
100%
day 14
affected eggs/embryos/larvae total percentage of affected eggs/embryos/larvae on slide
100%
day 14
larva number hatched none (< 10 %)
day 13
egg without cuticle embryo/egg without visible larval cuticle in cuticle preparation
100%
day 15
affected eggs/embryos/larvae total percentage of affected eggs/embryos/larvae on slide
100%
day 15
eclosion not fulfilled (with pupal and adult features)
20%
day 3
adult lethality
20%
day 7