Status
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Gene information
General information
TC012344 Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007424.3: 5126598..5187372
Sequence information
Transcripts / Proteins (2) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    TC012344
    iBeetle screen iB_06438

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 20.0% (includes death as pupa, adult)

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 2 (3 dpi)
    Days post injection


    Analysis of embryonic musculature and early development
    number of eggs/embryos/larvae on slide: > 50 embryo/egg not developed/not fertilized - Penetrance (percentage of animals/eggs on slide): more than 80%

    embryo/egg with embryonic tissue, no cuticle, but muscle fluorescence - Penetrance (percentage of animals/eggs on slide): less than 30%

    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: > 50
    embryo/egg without visible larval cuticle in cuticle preparation - Penetrance (percentage of animals/eggs on slide): more than 80%
    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 0.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 100.0% (includes death as larva, prepupa, pupa, adult)

    eclosion delayed (still pupa) - Number of animals showing the phenotype: 10 (16 dpi)
    Days post injection


    eclosion not fulfilled (died as pupa) - Number of animals showing the phenotype: 10 (19 dpi)
    Days post injection


    Pupal morphology
    elytra partially blistered - Number of animals showing the phenotype: 10

    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC012344 RA
      MLVKRCTME EKERKTRHM FLGIKTYLF IVCLASVPH 
      DALAENSLQ APRFTTSSA SSSIIRLGT TKIIQCQAF 
      GNPSPQFRW LKDWVPITE FSTDAYYKI ISASHKDEG 
      SYRCIAANK IGSILSEEM KILVAYMKV FEDQTEKSE 
      SVVEGQAAI LNLPEIESK PKPEVTWHT ESGQLPYAQ 
      KYAKSKSNQ LIILSTDKS DQKAYRARA INTQEGKEE 
      NSAFIRLTV QESSDHKEI APQIIVPPE DVKIVRGTA 
      QTTLDCIAN ARPLHELET LWFKDDILI ENGGMYSLN 
      DIWNRSLTL ISVNTTQSG QYECRVRLR SERFDTVTA 
      KAIVTVLEK PRFVSATRA ETLGEYGTP ISLPCDVVG 
      IPKPNVTWY KNSQEVDLT DKRYVLEED NSLRIKKLL 
      INDSGMFQC FAKSEAGES SISTWLKVK TAGPVMELG 
      PQNATVLDG KDATLACRA VGAPTPNIT WFYKGDLIE 
      TSSRVQILD TGDLLIAAV KESDVGMYT CLRANEAGE 
      VRGSAHLGV LVRTQIIQP PVDTRVLLG HTATLQCKI 
      SSDPAVPFD LRWYKNKQA LNPKASSRI SILKDGTLE 
      IQAVRAADV GLYTCSIKS PGGNETRSA KLSVIELPY 
      APTNVKAER LDTASQRAV NVSWIPGFD GNSPIKQFI 
      IQKRELPEL GPIPDPLLN WVTELSNVS AEQRWILLT 
      NLKAAAAYQ FRVSAVNSV GEGSPSEPS NQVMLPQEA 
      PSGPPVGFV GSARSSSEI ITQWQPPLE EHRNGQILG 
      YIIRYKLFG YTNSPWIVQ NITNEAQRN YLIQDLITW 
      KDYIVQIAA YNNKGVGVF TEGARIKTK EGVPEAPPI 
      IQTVVPLNS TTIQITWKP PDPQKINGI NQGYKIQAW 
      QTDKNGDLF EAKMITVHP NLLDPNQEQ TALMTGLEK 
      FTDYNVTVL CFTDPGDGE ISEFVPVKT KEDVPDEVS 
      NLQFDDISD RAVKVIWQP PKHINGILT GYQIRYQIR 
      DKPDTVKIK NLTADTLSL KVTDLQATT HYKFEVTAW 
      TAMGAGPPK VAIIQSGVE PVLPHPPNK LALSNIEAF 
      SVVLQFTPG FDGNSSITK WTVEAQTAR NASWFVVFE 
      ISDPDATTI TVTGLVPFT VYKLRLIAN NVVGASEPS 
      EASKEFQTI QAPPAHPPK NVTVRAMSA TEVRVRWIP 
      LQQIEWFGN PRGYSISYV EVRTGEKQT ATIDDHTAN 
      SHVITGLEE FALYEVSMQ ACNDVGCSM DGPVALERT 
      RESVPSFGP LNIEANATS STTIVVKWG DVPKEHQNG 
      LIEGYKVYY AAESKSPVQ YKLIASNST FTTTLTELR 
      KFVVYRIQV LAYTRLGDG EPSKPAVSV RTFEDVPGP 
      PSNVSFPDV SVTSARIIW DVPEEPNGE ILAYKVTYH 
      IDNVNVNNK YSKEFPPSD RTFRFTQLE PEKYYMFSV 
      TAQTRLGWG KTAHALVFT TNNRDTPQS PSMPQISRS 
      QVQSKQITF SWTPGRDGF APLRYYTVQ KMENGGPWQ 
      SLPERVDPQ LTSYTVSDL KPFTSYRFR IRATNDIGP 
      SPFSPESIE VRTYPAAPS KGVMNLKVV PITTTSVEV 
      YWDPVEEKY WNGDVKTGG YRVVFQPVS DYPTALQAT 
      PKEEIFGIN AKKMVLSEL LQDKNYEIV VVPFNSQGE 
      GPATPPVTV YVGEAVPTG EPRDLEGEA VSSTEVRLK 
      WKPPQQQQQ NGELLGYKI FYLVTNSPQ DFDEGHKFE 
      EEIEVIAAT MTSHSLVFL DKYTEYRIQ ILAFNPAGD 
      GPRSRPITV KTLQGLPGP PANLRFSDI TMNSLLVSW 
      DPPKKRNGD IIGYLVTYE TTEENERFS KQVKQKVTS 
      TELLLQTLE EEITYTFTV RAQTIDYGP SISDNVTTG 
      PQDGSPTTP KELTLIKTP SSVELHWVN GLTGKGPIL 
      GYYIESRKK DDQRWQTVT KSTNGPLQE FTVSYQSLL 
      PSTSYYFRV FPYNKFGIS CPAYTKDPV VTPSKLYLE 
      YSYLQYEPF YRQTWFMVA LAATSIIII IMIIAILCV 
      KSKSYKYKQ EGAQNSMGE LMAMSRDDM TADYYRTRN 
      GTSNLSSTL SKRSTLSRK PVHQQPPPM LGKSPPRPS 
      PASVPYNSD EESLKGYDE NPDDSSVTE KPSEMSSSE 
      SQGSESEND SVLSNSHSF VNHYANVNE PLRPSWKRQ 
      KPVRNFSSH TDSEPEGSA SLNGGQIII NNMARSRAP 
      LPGFSSFV
    • >TC012344 RB
      MLVKRCTME EKERKTRHM FLGIKTYLF IVCLASVPH 
      DALAENSLQ APRFTTSSA SSSIIRLGT TKIIQCQAF 
      GNPSPQFRW LKDWVPITE FSTDAYYKI ISASHKDEG 
      SYRCIAANK IGSILSEEM KILVAYMKV FEDQTEKSE 
      SVVEGQAAI LNLPEIESK PKPEVTWHT ESGQLPYAQ 
      KYAKSKSNQ LIILSTDKS DQKAYRARA INTQEGKEE 
      NSAFIRLTV QESSDHKEI APQIIVPPE DVKIVRGTA 
      QTTLDCIAN ARPLHELET LWFKDDILI ENGGMYSLN 
      DIWNRSLTL ISVNTTQSG QYECRVRLR SERFDTVTA 
      KAIVTVLEK PRFVSATRA ETLGEYGTP ISLPCDVVG 
      IPKPNVTWY KNSQEVDLT DKRYVLEED NSLRIKKLL 
      INDSGMFQC FAKSEAGES SISTWLKVK TAGPVMELG 
      PQNATVLDG KDATLACRA VGAPTPNIT WFYKGDLIE 
      TSSRVQILD TGDLLIAAV KESDVGMYT CLRANEAGE 
      VRGSAHLGV LVRTQIIQP PVDTRVLLG HTATLQCKI 
      SSDPAVPFD LRWYKNKQA LNPKASSRI SILKDGTLE 
      IQAVRAADV GLYTCSIKS PGGNETRSA KLSVIELPY 
      APTNVKAER LDTASQRAV NVSWIPGFD GNSPIKQFI 
      IQKRELPEL VPPISGPIP DPLLNWVTE LSNVSAEQR 
      WILLTNLKA AAAYQFRVS AVNSVGEGS PSEPSNQVM 
      LPQEAPSGP PVGFVGSAR SSSEIITQW QPPLEEHRN 
      GQILGYIIR YKLFGYTNS PWIVQNITN EAQRNYLIQ 
      DLITWKDYI VQIAAYNNK GVGVFTEGA RIKTKEGVP 
      EAPPIIQTV VPLNSTTIQ ITWKPPDPQ KINGINQGY 
      KIQAWQTDK NGDLFEAKM ITVHPNLLD PNQEQTALM 
      TGLEKFTDY NVTVLCFTD PGDGEISEF VPVKTKEDV 
      PDEVSNLQF DDISDRAVK VIWQPPKHI NGILTGYQI 
      RYQIRDKPD TVKIKNLTA DTLSLKVTD LQATTHYKF 
      EVTAWTAMG AGPPKVAII QSGVEPVLP HPPNKLALS 
      NIEAFSVVL QFTPGFDGN SSITKWTVE AQTARNASW 
      FVVFEISDP DATTITVTG LVPFTVYKL RLIANNVVG 
      ASEPSEASK EFQTIQAPP AHPPKNVTV RAMSATEVR 
      VRWIPLQQI EWFGNPRGY SISYVEVRT GEKQTATID 
      DHTANSHVI TGLEEFALY EVSMQACND VGCSMDGPV 
      ALERTRESV PSFGPLNIE ANATSSTTI VVKWGDVPK 
      EHQNGLIEG YKVYYAAES KSPVQYKLI ASNSTFTTT 
      LTELRKFVV YRIQVLAYT RLGDGEPSK PAVSVRTFE 
      DVPGPPSNV SFPDVSVTS ARIIWDVPE EPNGEILAY 
      KVTYHIDNV NVNNKYSKE FPPSDRTFR FTQLEPEKY 
      YMFSVTAQT RLGWGKTAH ALVFTTNNR DTPQSPSMP 
      QISRSQVQS KQITFSWTP GRDGFAPLR YYTVQKMEN 
      GGPWQSLPE RVDPQLTSY TVSDLKPFT SYRFRIRAT 
      NDIGPSPFS PESIEVRTY PAAPSKGVM NLKVVPITT 
      TSVEVYWDP VEEKYWNGD VKTGGYRVV FQPVSDYPT 
      ALQATPKEE IFGINAKKM VLSELLQDK NYEIVVVPF 
      NSQGEGPAT PPVTVYVGE AVPTGEPRD LEGEAVSST 
      EVRLKWKPP QQQQQNGEL LGYKIFYLV TNSPQDFDE 
      GHKFEEEIE VIAATMTSH SLVFLDKYT EYRIQILAF 
      NPAGDGPRS RPITVKTLQ GLPGPPANL RFSDITMNS 
      LLVSWDPPK KRNGDIIGY LVTYETTEE NERFSKQVK 
      QKVTSTELL LQTLEEEIT YTFTVRAQT IDYGPSISD 
      NVTTGPQDG SPTTPKELT LIKTPSSVE LHWVNGLTG 
      KGPILGYYI ESRKKDDQR WQTVTKSTN GPLQEFTVS 
      YQSLLPSTS YYFRVFPYN KFGISCPAY TKDPVVTPS 
      KLYLEYSYL QYEPFYRQT WFMVALAAT SIIIIIMII 
      AILCVKSKS YKYKQEGAQ NSMGELMAM SRDDMTADY 
      YRTRNGTSN LSSTLSKRS TLSRKPVHQ QPPPMLGKS 
      PPRPSPASV PYNSDEESL KGYDENPDD SSVTEKPSE 
      MSSSESQGS ESENDSVLS NSHSFVNHY ANVNEPLRP 
      SWKRQKPVR NFSSHTDSE PEGSASLNG GQIIINNMA 
      RSRAPLPGF SSFV
    CDS sequence
    • >TC012344 RA
      atgttggtg aagaggtgc accatggag gagaaggag 
      cggaaaaca cgacacatg tttttaggg attaaaact 
      tatttattt attgtatgt ttagccagt gttcctcac 
      gatgcttta gctgaaaat tcactgcaa gctccaaga 
      ttcacgacg tcgtcggct agcagtagt attattaga 
      ttaggaacg acaaaaatt atccagtgc caagccttt 
      ggcaatccc tcgccgcag tttaggtgg ctgaaagac 
      tgggtgcca ataactgaa ttttcaacc gatgcttac 
      tacaaaatc atctccgct agtcataag gatgagggc 
      agctacagg tgtatagca gccaacaaa atcggctca 
      atactcagc gaggaaatg aagattctc gtagcgtac 
      atgaaggtt ttcgaagac cagactgaa aagagcgag 
      tccgtcgtc gaagggcaa gctgcaatt ttaaatctt 
      ccggaaatc gagtcgaag cctaagcct gaggtgacc 
      tggcacacc gaaagcggt caattacca tacgctcaa 
      aaatacgcc aaatcgaaa tccaaccag cttatcatc 
      ctatcgact gacaagtcc gaccagaaa gcgtacagg 
      gcgcgtgca ataaacacc caagagggc aaggaagag 
      aacagcgct tttataaga ctgaccgtg caagaatcg 
      agcgatcac aaggaaatc gcgccgcaa attattgtc 
      cctcccgaa gacgtgaaa atcgtcaga gggacagct 
      cagacaact ttggattgc atcgccaac gccaggccg 
      ctgcacgaa ttggagacg ttgtggttc aaggatgat 
      attttgata gagaatggg ggaatgtac tcgctgaac 
      gatatttgg aacaggagt ttgacgtta atttcggtt 
      aacaccacc caaagtgga caatatgaa tgccgtgtt 
      aggctgaga tcggaacgg tttgatact gtcacagct 
      aaagcgatt gttactgta cttgaaaaa ccgagattt 
      gtgagcgcc acaagggcc gaaacgttg ggcgagtac 
      ggaacaccc attagccta ccttgcgat gtggttgga 
      ataccgaaa cccaatgtt acgtggtat aaaaacagc 
      caagaggtt gatctgacc gacaagagg tacgtcctc 
      gaagaagac aattcatta cgtattaaa aagctgtta 
      ataaacgac agcggcatg tttcaatgt tttgccaaa 
      agcgaggca ggggaaagt tcaatttcg acatggtta 
      aaggtgaaa actgcgggt cccgtgatg gaattaggg 
      cctcaaaat gccacagtt ctcgatggt aaagacgca 
      actttagct tgccgagct gtaggagcc ccaacaccc 
      aatatcacc tggttttac aaaggggat cttattgag 
      acctcaagc cgcgtccaa attctcgac actggagac 
      ttgctaata gctgctgtt aaggaatca gatgttgga 
      atgtacact tgtttaaga gccaacgaa gccggcgaa 
      gtacgaggc tctgcacat ttgggagtc ttggttcgc 
      acccaaatc atccaacct ccggtggac acgcgggtg 
      ctcctcggg catacggcc actcttcag tgtaaaatc 
      tcctccgat cctgctgtc cctttcgac ttgcggtgg 
      tacaaaaat aaacaagct ttaaatccg aaagcgagt 
      tcaaggata agtatttta aaggatggc actttggaa 
      atacaagca gttcgagct gcggatgtc ggtctctac 
      acatgctcg attaaatca cctggtggt aacgaaact 
      agatcggct aaattgagc gttatcgaa ctaccatac 
      gcccctact aatgttaaa gccgaaaga ctggatacg 
      gcctcgcaa agggcggtt aatgtcagt tggatacct 
      ggattcgat ggaaatagt ccgataaaa caatttatt 
      atacaaaaa agagagttg cctgaactt ggcccaatt 
      ccagatcct ttactcaat tgggtaact gaactcagt 
      aacgtatca gccgaacaa aggtggatt ttattaaca 
      aatttaaaa gcagctgct gcatatcag ttccgagtt 
      agcgccgtt aatagtgtg ggagaagga agtccgtcc 
      gaacccagt aaccaagtc atgttacct caagaagcc 
      ccttctgga cctcctgtt ggtttcgtg ggttcagcc 
      cgaagttcc tccgaaatc ataacacag tggcagcca 
      cctctcgaa gagcaccgt aacggtcaa atcctcggt 
      tacataatc agatacaaa ttattcggt tacaccaac 
      agtccttgg atcgttcaa aacataaca aacgaagcg 
      caaagaaat tacttaatt caagattta ataacttgg 
      aaagattac atcgtccag atcgccgcc tacaacaac 
      aaaggcgtt ggggttttc accgaaggc gcccgaatt 
      aagaccaag gagggcgtc cccgaagcc ccccctata 
      attcaaacg gtggtcccc ctgaactcc accacaatc 
      caaatcacg tggaaaccg ccagatccg caaaaaatc 
      aacggaatc aaccaggga tataaaatc caagcgtgg 
      caaaccgac aaaaacggc gacttattt gaagccaaa 
      atgataaca gttcacccg aatttactc gacccgaac 
      caggaacaa acggcgctt atgacgggc ctagagaag 
      ttcaccgac tacaatgtt acggtcctg tgcttcacc 
      gaccctggt gatggcgaa atcagcgag tttgtccca 
      gtgaaaaca aaagaagat gtacctgac gaagtcagc 
      aacttgcaa ttcgacgac attagcgac cgcgccgtt 
      aaagtcatc tggcagccc cccaagcac atcaacggc 
      atcttaacg gggtaccaa atccggtac caaattcgc 
      gacaagccc gacactgtc aaaatcaag aacctcaca 
      gccgatacc ctcagcctc aaagtaacc gacttgcaa 
      gccaccact cattacaaa tttgaggtc acggcctgg 
      actgcaatg ggggcaggc ccccctaaa gtggcgatc 
      atccagtcg ggggtggag cccgtcttg ccccatccc 
      cccaacaaa ctcgcctta tccaacatt gaggccttc 
      tctgtagtt ttgcaattc acccccggc tttgacggc 
      aactcctcc atcaccaag tggacggtg gaggcccaa 
      actgcgcgc aacgcctcc tggtttgtc gttttcgaa 
      ataagcgat ccagacgca actacgatt actgttacg 
      ggacttgtc cctttcact gtctataaa ctgcggttg 
      attgcgaat aatgtcgtg ggggcttcc gagccctcc 
      gaagcctcc aaggagttc cagacgatc caagcgccc 
      ccagcacac cccccgaag aacgtcaca gtgcgggcc 
      atgagcgcg actgaagtg agggttcgc tggattcct 
      ctgcagcaa atcgaatgg ttcgggaac ccgcgaggg 
      tactcgatt agttacgtg gaggtgcga acgggggaa 
      aaacagacg gcgacaatt gacgatcat acggccaat 
      tcgcatgtg attaccgga ttggaggag tttgcgttg 
      tatgaagtg tccatgcag gcgtgcaat gacgtgggg 
      tgttccatg gacgggccc gtggctttg gagaggacc 
      agggagtca gtaccatcg ttcgggccg ttaaacatc 
      gaagcgaac gctacctct agcacaaca atcgtagtg 
      aaatggggt gacgtcccg aaagaacac caaaacggc 
      ctaattgaa ggctacaaa gtttattac gccgccgaa 
      tcaaaatcg cccgtacag tacaagcta atcgccagc 
      aattccact tttacaacc actttgacc gaattgcgg 
      aaattcgtc gtttaccgc atccaggtc ctggcgtac 
      acacggctc ggcgacggc gagcccagc aaaccggcc 
      gtcagcgtg cgaaccttc gaagatgtc ccgggcccc 
      ccctcgaat gtgtcattc ccggacgtt tccgtcact 
      tcggccagg atcatctgg gacgtcccg gaagaaccc 
      aacggcgaa atcctggcg tacaaagtc acatatcat 
      atcgacaac gtgaacgtt aataataaa tactcgaag 
      gaatttccg ccgtctgat agaacgttc aggtttacg 
      cagttggag cctgagaag tattacatg ttttctgtg 
      actgctcag accagatta ggttggggc aagacagct 
      catgctttg gtttttaca acgaataat cgagacaca 
      ccacagtca ccatctatg ccacaaatc agtcgcagt 
      caggtacag agcaagcag atcactttc agctggaca 
      ccgggcaga gacggattc gcaccgttg agatattat 
      acggtccaa aaaatggaa aatgggggc ccttggcag 
      tcccttccc gaacgtgtg gaccctcaa ctcacctca 
      tacaccgtc tctgacctc aaacccttc acttcatac 
      cgcttcaga atccgcgca acgaacgat ataggtccc 
      agccccttc agtcccgaa tccatcgaa gtccgcact 
      tatccagca gcccccagc aaaggcgtc atgaactta 
      aaagtagtt cccataaca acgacaagt gtcgaagtc 
      tattgggac ccagttgag gagaagtac tggaacggg 
      gacgtcaaa acagggggc tatagagta gtctttcaa 
      cccgtctct gactatcca actgcactg caggcaaca 
      cccaaggag gaaattttc ggaatcaat gccaaaaaa 
      atggttctg agcgaatta ttgcaagac aagaattat 
      gagatagtt gtggtgccg tttaattcg caaggggag 
      ggccccgca acgccccct gtcacagtg tatgtaggg 
      gaagccgtc ccaactggt gaaccaagg gacttggag 
      ggcgaagct gtttcctcg acggaagtt cgcttgaaa 
      tggaagccg ccacagcag cagcaacaa aacggcgaa 
      ttgttggga tacaagata ttttatttg gtgacaaac 
      tcgccgcaa gattttgac gagggccac aagttcgag 
      gaggaaatc gaagtgatt gcagctacg atgacctcg 
      cacagcctt gtctttctc gacaaatac accgaatat 
      cgcatacaa attctggcg tttaaccca gcaggtgat 
      ggaccacga tcgcgcccc atcacagtt aagaccctt 
      caaggtctc cctggtcca ccagccaat ctacgcttt 
      tctgacata acgatgaat agcttgctc gtgtcgtgg 
      gatcccccg aaaaaacgc aacggtgac ataatcgga 
      taccttgtc acgtatgag acgaccgag gagaacgaa 
      cgttttagt aaacaagtc aagcagaaa gtgacgtcg 
      acggaactc ttgctacaa actttggag gaggaaatc 
      acttacacg ttcacagtg cgggcacaa accatcgat 
      tatgggccc tctatttcg gataacgtc accacaggg 
      ccacaggac ggctcccca acgacgcca aaagaactc 
      actttgatt aaaacaccg tcaagtgtg gagctgcac 
      tgggtcaat ggcttgacc ggaaagggg ccaattctg 
      ggctactat atcgaatcg aggaaaaaa gatgaccag 
      aggtggcaa acagtcacg aaatcgaca aacgggcct 
      ttgcaagaa tttacagtt tcgtaccaa agtctcctc 
      ccctcaacc tcttactat ttcagagtt tttccttac 
      aataaattc ggtattagt tgtcccgcg tacaccaaa 
      gacccggtc gtaacaccg tcaaaactg tacttggaa 
      tatagctac ttacagtat gaacccttc taccgacag 
      acctggttc atggtcgcc ctggcagcg acctccatc 
      atcattatc ataatgata attgcgatt ttgtgcgtt 
      aagagcaaa agttacaaa tataaacaa gaaggtgcc 
      caaaatagt atgggcgaa ctcatggca atgtcacgc 
      gacgacatg accgctgac tattaccga actcgcaac 
      ggcacaagt aacctaagc tcgactctt tcaaaacgt 
      agcacttta tcccgcaag ccggtccat caacaaccc 
      cctccaatg ttggggaaa tcccctccg agaccatcg 
      ccggcttca gtgccctac aactcagac gaggaaagt 
      ctcaagggc tacgatgag aatcccgac gatagcagc 
      gtgaccgag aagccgtca gaaatgagc tcttctgaa 
      tcccagggt tcggaaagc gaaaacgac agtgtcctc 
      tcgaattcg cactcgttt gtgaaccac tacgccaat 
      gtgaacgag ccattgcga ccgtcctgg aagcgccaa 
      aagccggtc aggaatttc tcgagtcac actgattcg 
      gaaccggaa ggttcggcg agtttgaat ggaggacag 
      attatcatt aataacatg gcgaggtca agggcgccc 
      ctacccgga ttttcgtcg tttgtttaa
    • >TC012344 RB
      atgttggtg aagaggtgc accatggag gagaaggag 
      cggaaaaca cgacacatg tttttaggg attaaaact 
      tatttattt attgtatgt ttagccagt gttcctcac 
      gatgcttta gctgaaaat tcactgcaa gctccaaga 
      ttcacgacg tcgtcggct agcagtagt attattaga 
      ttaggaacg acaaaaatt atccagtgc caagccttt 
      ggcaatccc tcgccgcag tttaggtgg ctgaaagac 
      tgggtgcca ataactgaa ttttcaacc gatgcttac 
      tacaaaatc atctccgct agtcataag gatgagggc 
      agctacagg tgtatagca gccaacaaa atcggctca 
      atactcagc gaggaaatg aagattctc gtagcgtac 
      atgaaggtt ttcgaagac cagactgaa aagagcgag 
      tccgtcgtc gaagggcaa gctgcaatt ttaaatctt 
      ccggaaatc gagtcgaag cctaagcct gaggtgacc 
      tggcacacc gaaagcggt caattacca tacgctcaa 
      aaatacgcc aaatcgaaa tccaaccag cttatcatc 
      ctatcgact gacaagtcc gaccagaaa gcgtacagg 
      gcgcgtgca ataaacacc caagagggc aaggaagag 
      aacagcgct tttataaga ctgaccgtg caagaatcg 
      agcgatcac aaggaaatc gcgccgcaa attattgtc 
      cctcccgaa gacgtgaaa atcgtcaga gggacagct 
      cagacaact ttggattgc atcgccaac gccaggccg 
      ctgcacgaa ttggagacg ttgtggttc aaggatgat 
      attttgata gagaatggg ggaatgtac tcgctgaac 
      gatatttgg aacaggagt ttgacgtta atttcggtt 
      aacaccacc caaagtgga caatatgaa tgccgtgtt 
      aggctgaga tcggaacgg tttgatact gtcacagct 
      aaagcgatt gttactgta cttgaaaaa ccgagattt 
      gtgagcgcc acaagggcc gaaacgttg ggcgagtac 
      ggaacaccc attagccta ccttgcgat gtggttgga 
      ataccgaaa cccaatgtt acgtggtat aaaaacagc 
      caagaggtt gatctgacc gacaagagg tacgtcctc 
      gaagaagac aattcatta cgtattaaa aagctgtta 
      ataaacgac agcggcatg tttcaatgt tttgccaaa 
      agcgaggca ggggaaagt tcaatttcg acatggtta 
      aaggtgaaa actgcgggt cccgtgatg gaattaggg 
      cctcaaaat gccacagtt ctcgatggt aaagacgca 
      actttagct tgccgagct gtaggagcc ccaacaccc 
      aatatcacc tggttttac aaaggggat cttattgag 
      acctcaagc cgcgtccaa attctcgac actggagac 
      ttgctaata gctgctgtt aaggaatca gatgttgga 
      atgtacact tgtttaaga gccaacgaa gccggcgaa 
      gtacgaggc tctgcacat ttgggagtc ttggttcgc 
      acccaaatc atccaacct ccggtggac acgcgggtg 
      ctcctcggg catacggcc actcttcag tgtaaaatc 
      tcctccgat cctgctgtc cctttcgac ttgcggtgg 
      tacaaaaat aaacaagct ttaaatccg aaagcgagt 
      tcaaggata agtatttta aaggatggc actttggaa 
      atacaagca gttcgagct gcggatgtc ggtctctac 
      acatgctcg attaaatca cctggtggt aacgaaact 
      agatcggct aaattgagc gttatcgaa ctaccatac 
      gcccctact aatgttaaa gccgaaaga ctggatacg 
      gcctcgcaa agggcggtt aatgtcagt tggatacct 
      ggattcgat ggaaatagt ccgataaaa caatttatt 
      atacaaaaa agagagttg cctgaactt gttcctccg 
      atttcaggc ccaattcca gatccttta ctcaattgg 
      gtaactgaa ctcagtaac gtatcagcc gaacaaagg 
      tggatttta ttaacaaat ttaaaagca gctgctgca 
      tatcagttc cgagttagc gccgttaat agtgtggga 
      gaaggaagt ccgtccgaa cccagtaac caagtcatg 
      ttacctcaa gaagcccct tctggacct cctgttggt 
      ttcgtgggt tcagcccga agttcctcc gaaatcata 
      acacagtgg cagccacct ctcgaagag caccgtaac 
      ggtcaaatc ctcggttac ataatcaga tacaaatta 
      ttcggttac accaacagt ccttggatc gttcaaaac 
      ataacaaac gaagcgcaa agaaattac ttaattcaa 
      gatttaata acttggaaa gattacatc gtccagatc 
      gccgcctac aacaacaaa ggcgttggg gttttcacc 
      gaaggcgcc cgaattaag accaaggag ggcgtcccc 
      gaagccccc cctataatt caaacggtg gtccccctg 
      aactccacc acaatccaa atcacgtgg aaaccgcca 
      gatccgcaa aaaatcaac ggaatcaac cagggatat 
      aaaatccaa gcgtggcaa accgacaaa aacggcgac 
      ttatttgaa gccaaaatg ataacagtt cacccgaat 
      ttactcgac ccgaaccag gaacaaacg gcgcttatg 
      acgggccta gagaagttc accgactac aatgttacg 
      gtcctgtgc ttcaccgac cctggtgat ggcgaaatc 
      agcgagttt gtcccagtg aaaacaaaa gaagatgta 
      cctgacgaa gtcagcaac ttgcaattc gacgacatt 
      agcgaccgc gccgttaaa gtcatctgg cagcccccc 
      aagcacatc aacggcatc ttaacgggg taccaaatc 
      cggtaccaa attcgcgac aagcccgac actgtcaaa 
      atcaagaac ctcacagcc gataccctc agcctcaaa 
      gtaaccgac ttgcaagcc accactcat tacaaattt 
      gaggtcacg gcctggact gcaatgggg gcaggcccc 
      cctaaagtg gcgatcatc cagtcgggg gtggagccc 
      gtcttgccc catcccccc aacaaactc gccttatcc 
      aacattgag gccttctct gtagttttg caattcacc 
      cccggcttt gacggcaac tcctccatc accaagtgg 
      acggtggag gcccaaact gcgcgcaac gcctcctgg 
      tttgtcgtt ttcgaaata agcgatcca gacgcaact 
      acgattact gttacggga cttgtccct ttcactgtc 
      tataaactg cggttgatt gcgaataat gtcgtgggg 
      gcttccgag ccctccgaa gcctccaag gagttccag 
      acgatccaa gcgccccca gcacacccc ccgaagaac 
      gtcacagtg cgggccatg agcgcgact gaagtgagg 
      gttcgctgg attcctctg cagcaaatc gaatggttc 
      gggaacccg cgagggtac tcgattagt tacgtggag 
      gtgcgaacg ggggaaaaa cagacggcg acaattgac 
      gatcatacg gccaattcg catgtgatt accggattg 
      gaggagttt gcgttgtat gaagtgtcc atgcaggcg 
      tgcaatgac gtggggtgt tccatggac gggcccgtg 
      gctttggag aggaccagg gagtcagta ccatcgttc 
      gggccgtta aacatcgaa gcgaacgct acctctagc 
      acaacaatc gtagtgaaa tggggtgac gtcccgaaa 
      gaacaccaa aacggccta attgaaggc tacaaagtt 
      tattacgcc gccgaatca aaatcgccc gtacagtac 
      aagctaatc gccagcaat tccactttt acaaccact 
      ttgaccgaa ttgcggaaa ttcgtcgtt taccgcatc 
      caggtcctg gcgtacaca cggctcggc gacggcgag 
      cccagcaaa ccggccgtc agcgtgcga accttcgaa 
      gatgtcccg ggccccccc tcgaatgtg tcattcccg 
      gacgtttcc gtcacttcg gccaggatc atctgggac 
      gtcccggaa gaacccaac ggcgaaatc ctggcgtac 
      aaagtcaca tatcatatc gacaacgtg aacgttaat 
      aataaatac tcgaaggaa tttccgccg tctgataga 
      acgttcagg tttacgcag ttggagcct gagaagtat 
      tacatgttt tctgtgact gctcagacc agattaggt 
      tggggcaag acagctcat gctttggtt tttacaacg 
      aataatcga gacacacca cagtcacca tctatgcca 
      caaatcagt cgcagtcag gtacagagc aagcagatc 
      actttcagc tggacaccg ggcagagac ggattcgca 
      ccgttgaga tattatacg gtccaaaaa atggaaaat 
      gggggccct tggcagtcc cttcccgaa cgtgtggac 
      cctcaactc acctcatac accgtctct gacctcaaa 
      cccttcact tcataccgc ttcagaatc cgcgcaacg 
      aacgatata ggtcccagc cccttcagt cccgaatcc 
      atcgaagtc cgcacttat ccagcagcc cccagcaaa 
      ggcgtcatg aacttaaaa gtagttccc ataacaacg 
      acaagtgtc gaagtctat tgggaccca gttgaggag 
      aagtactgg aacggggac gtcaaaaca gggggctat 
      agagtagtc tttcaaccc gtctctgac tatccaact 
      gcactgcag gcaacaccc aaggaggaa attttcgga 
      atcaatgcc aaaaaaatg gttctgagc gaattattg 
      caagacaag aattatgag atagttgtg gtgccgttt 
      aattcgcaa ggggagggc cccgcaacg ccccctgtc 
      acagtgtat gtaggggaa gccgtccca actggtgaa 
      ccaagggac ttggagggc gaagctgtt tcctcgacg 
      gaagttcgc ttgaaatgg aagccgcca cagcagcag 
      caacaaaac ggcgaattg ttgggatac aagatattt 
      tatttggtg acaaactcg ccgcaagat tttgacgag 
      ggccacaag ttcgaggag gaaatcgaa gtgattgca 
      gctacgatg acctcgcac agccttgtc tttctcgac 
      aaatacacc gaatatcgc atacaaatt ctggcgttt 
      aacccagca ggtgatgga ccacgatcg cgccccatc 
      acagttaag acccttcaa ggtctccct ggtccacca 
      gccaatcta cgcttttct gacataacg atgaatagc 
      ttgctcgtg tcgtgggat cccccgaaa aaacgcaac 
      ggtgacata atcggatac cttgtcacg tatgagacg 
      accgaggag aacgaacgt tttagtaaa caagtcaag 
      cagaaagtg acgtcgacg gaactcttg ctacaaact 
      ttggaggag gaaatcact tacacgttc acagtgcgg 
      gcacaaacc atcgattat gggccctct atttcggat 
      aacgtcacc acagggcca caggacggc tccccaacg 
      acgccaaaa gaactcact ttgattaaa acaccgtca 
      agtgtggag ctgcactgg gtcaatggc ttgaccgga 
      aaggggcca attctgggc tactatatc gaatcgagg 
      aaaaaagat gaccagagg tggcaaaca gtcacgaaa 
      tcgacaaac gggcctttg caagaattt acagtttcg 
      taccaaagt ctcctcccc tcaacctct tactatttc 
      agagttttt ccttacaat aaattcggt attagttgt 
      cccgcgtac accaaagac ccggtcgta acaccgtca 
      aaactgtac ttggaatat agctactta cagtatgaa 
      cccttctac cgacagacc tggttcatg gtcgccctg 
      gcagcgacc tccatcatc attatcata atgataatt 
      gcgattttg tgcgttaag agcaaaagt tacaaatat 
      aaacaagaa ggtgcccaa aatagtatg ggcgaactc 
      atggcaatg tcacgcgac gacatgacc gctgactat 
      taccgaact cgcaacggc acaagtaac ctaagctcg 
      actctttca aaacgtagc actttatcc cgcaagccg 
      gtccatcaa caaccccct ccaatgttg gggaaatcc 
      cctccgaga ccatcgccg gcttcagtg ccctacaac 
      tcagacgag gaaagtctc aagggctac gatgagaat 
      cccgacgat agcagcgtg accgagaag ccgtcagaa 
      atgagctct tctgaatcc cagggttcg gaaagcgaa 
      aacgacagt gtcctctcg aattcgcac tcgtttgtg 
      aaccactac gccaatgtg aacgagcca ttgcgaccg 
      tcctggaag cgccaaaag ccggtcagg aatttctcg 
      agtcacact gattcggaa ccggaaggt tcggcgagt 
      ttgaatgga ggacagatt atcattaat aacatggcg 
      aggtcaagg gcgccccta cccggattt tcgtcgttt 
      gtttaa
    mRNA sequence
    • >TC012344 RA
      agcggggat tatttccgt aaaagtttt gttgtgtgt 
      ttgtgcggt ggtgtgcgt gcacgtcgt taaatgtct 
      tcgttcgaa aagacgcgc acaacaaaa agttcaact 
      cgcaacttt ggcaactta cgcagcgaa gtctttcgg 
      ttaatggtc gaaaaacca gcgaaatgg tttagtact 
      tgtgctcat taggagaga ggggacggc tatgtaaaa 
      gttaacggt gcgtttgtt gctgcatct acaggtggt 
      atcgtgaga tgccgatgc cgttttacg gtccgtggt 
      gttaaaaat gaagtgaaa aagtgcatc acgatgtaa 
      aatccagtg agttttcca acttttcac ctgttttgt 
      gagactgaa cgaaactgc taaaatgtt ggtgaagag 
      gtgcaccat ggaggagaa ggagcggaa aacacgaca 
      catgttttt agggattaa aacttattt atttattgt 
      atgtttagc cagtgttcc tcacgatgc tttagctga 
      aaattcact gcaagctcc aagattcac gacgtcgtc 
      ggctagcag tagtattat tagattagg aacgacaaa 
      aattatcca gtgccaagc ctttggcaa tccctcgcc 
      gcagtttag gtggctgaa agactgggt gccaataac 
      tgaattttc aaccgatgc ttactacaa aatcatctc 
      cgctagtca taaggatga gggcagcta caggtgtat 
      agcagccaa caaaatcgg ctcaatact cagcgagga 
      aatgaagat tctcgtagc gtacatgaa ggttttcga 
      agaccagac tgaaaagag cgagtccgt cgtcgaagg 
      gcaagctgc aattttaaa tcttccgga aatcgagtc 
      gaagcctaa gcctgaggt gacctggca caccgaaag 
      cggtcaatt accatacgc tcaaaaata cgccaaatc 
      gaaatccaa ccagcttat catcctatc gactgacaa 
      gtccgacca gaaagcgta cagggcgcg tgcaataaa 
      cacccaaga gggcaagga agagaacag cgcttttat 
      aagactgac cgtgcaaga atcgagcga tcacaagga 
      aatcgcgcc gcaaattat tgtccctcc cgaagacgt 
      gaaaatcgt cagagggac agctcagac aactttgga 
      ttgcatcgc caacgccag gccgctgca cgaattgga 
      gacgttgtg gttcaagga tgatatttt gatagagaa 
      tgggggaat gtactcgct gaacgatat ttggaacag 
      gagtttgac gttaatttc ggttaacac cacccaaag 
      tggacaata tgaatgccg tgttaggct gagatcgga 
      acggtttga tactgtcac agctaaagc gattgttac 
      tgtacttga aaaaccgag atttgtgag cgccacaag 
      ggccgaaac gttgggcga gtacggaac acccattag 
      cctaccttg cgatgtggt tggaatacc gaaacccaa 
      tgttacgtg gtataaaaa cagccaaga ggttgatct 
      gaccgacaa gaggtacgt cctcgaaga agacaattc 
      attacgtat taaaaagct gttaataaa cgacagcgg 
      catgtttca atgttttgc caaaagcga ggcagggga 
      aagttcaat ttcgacatg gttaaaggt gaaaactgc 
      gggtcccgt gatggaatt agggcctca aaatgccac 
      agttctcga tggtaaaga cgcaacttt agcttgccg 
      agctgtagg agccccaac acccaatat cacctggtt 
      ttacaaagg ggatcttat tgagacctc aagccgcgt 
      ccaaattct cgacactgg agacttgct aatagctgc 
      tgttaagga atcagatgt tggaatgta cacttgttt 
      aagagccaa cgaagccgg cgaagtacg aggctctgc 
      acatttggg agtcttggt tcgcaccca aatcatcca 
      acctccggt ggacacgcg ggtgctcct cgggcatac 
      ggccactct tcagtgtaa aatctcctc cgatcctgc 
      tgtcccttt cgacttgcg gtggtacaa aaataaaca 
      agctttaaa tccgaaagc gagttcaag gataagtat 
      tttaaagga tggcacttt ggaaataca agcagttcg 
      agctgcgga tgtcggtct ctacacatg ctcgattaa 
      atcacctgg tggtaacga aactagatc ggctaaatt 
      gagcgttat cgaactacc atacgcccc tactaatgt 
      taaagccga aagactgga tacggcctc gcaaagggc 
      ggttaatgt cagttggat acctggatt cgatggaaa 
      tagtccgat aaaacaatt tattataca aaaaagaga 
      gttgcctga acttggccc aattccaga tcctttact 
      caattgggt aactgaact cagtaacgt atcagccga 
      acaaaggtg gattttatt aacaaattt aaaagcagc 
      tgctgcata tcagttccg agttagcgc cgttaatag 
      tgtgggaga aggaagtcc gtccgaacc cagtaacca 
      agtcatgtt acctcaaga agccccttc tggacctcc 
      tgttggttt cgtgggttc agcccgaag ttcctccga 
      aatcataac acagtggca gccacctct cgaagagca 
      ccgtaacgg tcaaatcct cggttacat aatcagata 
      caaattatt cggttacac caacagtcc ttggatcgt 
      tcaaaacat aacaaacga agcgcaaag aaattactt 
      aattcaaga tttaataac ttggaaaga ttacatcgt 
      ccagatcgc cgcctacaa caacaaagg cgttggggt 
      tttcaccga aggcgcccg aattaagac caaggaggg 
      cgtccccga agccccccc tataattca aacggtggt 
      ccccctgaa ctccaccac aatccaaat cacgtggaa 
      accgccaga tccgcaaaa aatcaacgg aatcaacca 
      gggatataa aatccaagc gtggcaaac cgacaaaaa 
      cggcgactt atttgaagc caaaatgat aacagttca 
      cccgaattt actcgaccc gaaccagga acaaacggc 
      gcttatgac gggcctaga gaagttcac cgactacaa 
      tgttacggt cctgtgctt caccgaccc tggtgatgg 
      cgaaatcag cgagtttgt cccagtgaa aacaaaaga 
      agatgtacc tgacgaagt cagcaactt gcaattcga 
      cgacattag cgaccgcgc cgttaaagt catctggca 
      gccccccaa gcacatcaa cggcatctt aacggggta 
      ccaaatccg gtaccaaat tcgcgacaa gcccgacac 
      tgtcaaaat caagaacct cacagccga taccctcag 
      cctcaaagt aaccgactt gcaagccac cactcatta 
      caaatttga ggtcacggc ctggactgc aatgggggc 
      aggcccccc taaagtggc gatcatcca gtcgggggt 
      ggagcccgt cttgcccca tccccccaa caaactcgc 
      cttatccaa cattgaggc cttctctgt agttttgca 
      attcacccc cggctttga cggcaactc ctccatcac 
      caagtggac ggtggaggc ccaaactgc gcgcaacgc 
      ctcctggtt tgtcgtttt cgaaataag cgatccaga 
      cgcaactac gattactgt tacgggact tgtcccttt 
      cactgtcta taaactgcg gttgattgc gaataatgt 
      cgtgggggc ttccgagcc ctccgaagc ctccaagga 
      gttccagac gatccaagc gcccccagc acacccccc 
      gaagaacgt cacagtgcg ggccatgag cgcgactga 
      agtgagggt tcgctggat tcctctgca gcaaatcga 
      atggttcgg gaacccgcg agggtactc gattagtta 
      cgtggaggt gcgaacggg ggaaaaaca gacggcgac 
      aattgacga tcatacggc caattcgca tgtgattac 
      cggattgga ggagtttgc gttgtatga agtgtccat 
      gcaggcgtg caatgacgt ggggtgttc catggacgg 
      gcccgtggc tttggagag gaccaggga gtcagtacc 
      atcgttcgg gccgttaaa catcgaagc gaacgctac 
      ctctagcac aacaatcgt agtgaaatg gggtgacgt 
      cccgaaaga acaccaaaa cggcctaat tgaaggcta 
      caaagttta ttacgccgc cgaatcaaa atcgcccgt 
      acagtacaa gctaatcgc cagcaattc cacttttac 
      aaccacttt gaccgaatt gcggaaatt cgtcgttta 
      ccgcatcca ggtcctggc gtacacacg gctcggcga 
      cggcgagcc cagcaaacc ggccgtcag cgtgcgaac 
      cttcgaaga tgtcccggg ccccccctc gaatgtgtc 
      attcccgga cgtttccgt cacttcggc caggatcat 
      ctgggacgt cccggaaga acccaacgg cgaaatcct 
      ggcgtacaa agtcacata tcatatcga caacgtgaa 
      cgttaataa taaatactc gaaggaatt tccgccgtc 
      tgatagaac gttcaggtt tacgcagtt ggagcctga 
      gaagtatta catgttttc tgtgactgc tcagaccag 
      attaggttg gggcaagac agctcatgc tttggtttt 
      tacaacgaa taatcgaga cacaccaca gtcaccatc 
      tatgccaca aatcagtcg cagtcaggt acagagcaa 
      gcagatcac tttcagctg gacaccggg cagagacgg 
      attcgcacc gttgagata ttatacggt ccaaaaaat 
      ggaaaatgg gggcccttg gcagtccct tcccgaacg 
      tgtggaccc tcaactcac ctcatacac cgtctctga 
      cctcaaacc cttcacttc ataccgctt cagaatccg 
      cgcaacgaa cgatatagg tcccagccc cttcagtcc 
      cgaatccat cgaagtccg cacttatcc agcagcccc 
      cagcaaagg cgtcatgaa cttaaaagt agttcccat 
      aacaacgac aagtgtcga agtctattg ggacccagt 
      tgaggagaa gtactggaa cggggacgt caaaacagg 
      gggctatag agtagtctt tcaacccgt ctctgacta 
      tccaactgc actgcaggc aacacccaa ggaggaaat 
      tttcggaat caatgccaa aaaaatggt tctgagcga 
      attattgca agacaagaa ttatgagat agttgtggt 
      gccgtttaa ttcgcaagg ggagggccc cgcaacgcc 
      ccctgtcac agtgtatgt aggggaagc cgtcccaac 
      tggtgaacc aagggactt ggagggcga agctgtttc 
      ctcgacgga agttcgctt gaaatggaa gccgccaca 
      gcagcagca acaaaacgg cgaattgtt gggatacaa 
      gatatttta tttggtgac aaactcgcc gcaagattt 
      tgacgaggg ccacaagtt cgaggagga aatcgaagt 
      gattgcagc tacgatgac ctcgcacag ccttgtctt 
      tctcgacaa atacaccga atatcgcat acaaattct 
      ggcgtttaa cccagcagg tgatggacc acgatcgcg 
      ccccatcac agttaagac ccttcaagg tctccctgg 
      tccaccagc caatctacg cttttctga cataacgat 
      gaatagctt gctcgtgtc gtgggatcc cccgaaaaa 
      acgcaacgg tgacataat cggatacct tgtcacgta 
      tgagacgac cgaggagaa cgaacgttt tagtaaaca 
      agtcaagca gaaagtgac gtcgacgga actcttgct 
      acaaacttt ggaggagga aatcactta cacgttcac 
      agtgcgggc acaaaccat cgattatgg gccctctat 
      ttcggataa cgtcaccac agggccaca ggacggctc 
      cccaacgac gccaaaaga actcacttt gattaaaac 
      accgtcaag tgtggagct gcactgggt caatggctt 
      gaccggaaa ggggccaat tctgggcta ctatatcga 
      atcgaggaa aaaagatga ccagaggtg gcaaacagt 
      cacgaaatc gacaaacgg gcctttgca agaatttac 
      agtttcgta ccaaagtct cctcccctc aacctctta 
      ctatttcag agtttttcc ttacaataa attcggtat 
      tagttgtcc cgcgtacac caaagaccc ggtcgtaac 
      accgtcaaa actgtactt ggaatatag ctacttaca 
      gtatgaacc cttctaccg acagacctg gttcatggt 
      cgccctggc agcgacctc catcatcat tatcataat 
      gataattgc gattttgtg cgttaagag caaaagtta 
      caaatataa acaagaagg tgcccaaaa tagtatggg 
      cgaactcat ggcaatgtc acgcgacga catgaccgc 
      tgactatta ccgaactcg caacggcac aagtaacct 
      aagctcgac tctttcaaa acgtagcac tttatcccg 
      caagccggt ccatcaaca accccctcc aatgttggg 
      gaaatcccc tccgagacc atcgccggc ttcagtgcc 
      ctacaactc agacgagga aagtctcaa gggctacga 
      tgagaatcc cgacgatag cagcgtgac cgagaagcc 
      gtcagaaat gagctcttc tgaatccca gggttcgga 
      aagcgaaaa cgacagtgt cctctcgaa ttcgcactc 
      gtttgtgaa ccactacgc caatgtgaa cgagccatt 
      gcgaccgtc ctggaagcg ccaaaagcc ggtcaggaa 
      tttctcgag tcacactga ttcggaacc ggaaggttc 
      ggcgagttt gaatggagg acagattat cattaataa 
      catggcgag gtcaagggc gcccctacc cggattttc 
      gtcgtttgt ttaatgata gctgaatta agaaaattt 
      gataatgcc actgttact taagtatca gattttcgt 
      gatctaggc aaagacttg acatttttg tacatattt 
      ttaattcaa agtctatta agtgattag agtcagact 
      tactatttg tatataaaa cctgtagga ctttttact 
      gtagataac gtttcaaag cgcatctat tcacat
    • >TC012344 RB
      agcggggat tatttccgt aaaagtttt gttgtgtgt 
      ttgtgcggt ggtgtgcgt gcacgtcgt taaatgtct 
      tcgttcgaa aagacgcgc acaacaaaa agttcaact 
      cgcaacttt ggcaactta cgcagcgaa gtctttcgg 
      ttaatggtc gaaaaacca gcgaaatgg tttagtact 
      tgtgctcat taggagaga ggggacggc tatgtaaaa 
      gttaacggt gcgtttgtt gctgcatct acaggtggt 
      atcgtgaga tgccgatgc cgttttacg gtccgtggt 
      gttaaaaat gaagtgaaa aagtgcatc acgatgtaa 
      aatccagtg agttttcca acttttcac ctgttttgt 
      gagactgaa cgaaactgc taaaatgtt ggtgaagag 
      gtgcaccat ggaggagaa ggagcggaa aacacgaca 
      catgttttt agggattaa aacttattt atttattgt 
      atgtttagc cagtgttcc tcacgatgc tttagctga 
      aaattcact gcaagctcc aagattcac gacgtcgtc 
      ggctagcag tagtattat tagattagg aacgacaaa 
      aattatcca gtgccaagc ctttggcaa tccctcgcc 
      gcagtttag gtggctgaa agactgggt gccaataac 
      tgaattttc aaccgatgc ttactacaa aatcatctc 
      cgctagtca taaggatga gggcagcta caggtgtat 
      agcagccaa caaaatcgg ctcaatact cagcgagga 
      aatgaagat tctcgtagc gtacatgaa ggttttcga 
      agaccagac tgaaaagag cgagtccgt cgtcgaagg 
      gcaagctgc aattttaaa tcttccgga aatcgagtc 
      gaagcctaa gcctgaggt gacctggca caccgaaag 
      cggtcaatt accatacgc tcaaaaata cgccaaatc 
      gaaatccaa ccagcttat catcctatc gactgacaa 
      gtccgacca gaaagcgta cagggcgcg tgcaataaa 
      cacccaaga gggcaagga agagaacag cgcttttat 
      aagactgac cgtgcaaga atcgagcga tcacaagga 
      aatcgcgcc gcaaattat tgtccctcc cgaagacgt 
      gaaaatcgt cagagggac agctcagac aactttgga 
      ttgcatcgc caacgccag gccgctgca cgaattgga 
      gacgttgtg gttcaagga tgatatttt gatagagaa 
      tgggggaat gtactcgct gaacgatat ttggaacag 
      gagtttgac gttaatttc ggttaacac cacccaaag 
      tggacaata tgaatgccg tgttaggct gagatcgga 
      acggtttga tactgtcac agctaaagc gattgttac 
      tgtacttga aaaaccgag atttgtgag cgccacaag 
      ggccgaaac gttgggcga gtacggaac acccattag 
      cctaccttg cgatgtggt tggaatacc gaaacccaa 
      tgttacgtg gtataaaaa cagccaaga ggttgatct 
      gaccgacaa gaggtacgt cctcgaaga agacaattc 
      attacgtat taaaaagct gttaataaa cgacagcgg 
      catgtttca atgttttgc caaaagcga ggcagggga 
      aagttcaat ttcgacatg gttaaaggt gaaaactgc 
      gggtcccgt gatggaatt agggcctca aaatgccac 
      agttctcga tggtaaaga cgcaacttt agcttgccg 
      agctgtagg agccccaac acccaatat cacctggtt 
      ttacaaagg ggatcttat tgagacctc aagccgcgt 
      ccaaattct cgacactgg agacttgct aatagctgc 
      tgttaagga atcagatgt tggaatgta cacttgttt 
      aagagccaa cgaagccgg cgaagtacg aggctctgc 
      acatttggg agtcttggt tcgcaccca aatcatcca 
      acctccggt ggacacgcg ggtgctcct cgggcatac 
      ggccactct tcagtgtaa aatctcctc cgatcctgc 
      tgtcccttt cgacttgcg gtggtacaa aaataaaca 
      agctttaaa tccgaaagc gagttcaag gataagtat 
      tttaaagga tggcacttt ggaaataca agcagttcg 
      agctgcgga tgtcggtct ctacacatg ctcgattaa 
      atcacctgg tggtaacga aactagatc ggctaaatt 
      gagcgttat cgaactacc atacgcccc tactaatgt 
      taaagccga aagactgga tacggcctc gcaaagggc 
      ggttaatgt cagttggat acctggatt cgatggaaa 
      tagtccgat aaaacaatt tattataca aaaaagaga 
      gttgcctga acttgttcc tccgatttc aggcccaat 
      tccagatcc tttactcaa ttgggtaac tgaactcag 
      taacgtatc agccgaaca aaggtggat tttattaac 
      aaatttaaa agcagctgc tgcatatca gttccgagt 
      tagcgccgt taatagtgt gggagaagg aagtccgtc 
      cgaacccag taaccaagt catgttacc tcaagaagc 
      cccttctgg acctcctgt tggtttcgt gggttcagc 
      ccgaagttc ctccgaaat cataacaca gtggcagcc 
      acctctcga agagcaccg taacggtca aatcctcgg 
      ttacataat cagatacaa attattcgg ttacaccaa 
      cagtccttg gatcgttca aaacataac aaacgaagc 
      gcaaagaaa ttacttaat tcaagattt aataacttg 
      gaaagatta catcgtcca gatcgccgc ctacaacaa 
      caaaggcgt tggggtttt caccgaagg cgcccgaat 
      taagaccaa ggagggcgt ccccgaagc cccccctat 
      aattcaaac ggtggtccc cctgaactc caccacaat 
      ccaaatcac gtggaaacc gccagatcc gcaaaaaat 
      caacggaat caaccaggg atataaaat ccaagcgtg 
      gcaaaccga caaaaacgg cgacttatt tgaagccaa 
      aatgataac agttcaccc gaatttact cgacccgaa 
      ccaggaaca aacggcgct tatgacggg cctagagaa 
      gttcaccga ctacaatgt tacggtcct gtgcttcac 
      cgaccctgg tgatggcga aatcagcga gtttgtccc 
      agtgaaaac aaaagaaga tgtacctga cgaagtcag 
      caacttgca attcgacga cattagcga ccgcgccgt 
      taaagtcat ctggcagcc ccccaagca catcaacgg 
      catcttaac ggggtacca aatccggta ccaaattcg 
      cgacaagcc cgacactgt caaaatcaa gaacctcac 
      agccgatac cctcagcct caaagtaac cgacttgca 
      agccaccac tcattacaa atttgaggt cacggcctg 
      gactgcaat gggggcagg cccccctaa agtggcgat 
      catccagtc gggggtgga gcccgtctt gccccatcc 
      ccccaacaa actcgcctt atccaacat tgaggcctt 
      ctctgtagt tttgcaatt cacccccgg ctttgacgg 
      caactcctc catcaccaa gtggacggt ggaggccca 
      aactgcgcg caacgcctc ctggtttgt cgttttcga 
      aataagcga tccagacgc aactacgat tactgttac 
      gggacttgt ccctttcac tgtctataa actgcggtt 
      gattgcgaa taatgtcgt gggggcttc cgagccctc 
      cgaagcctc caaggagtt ccagacgat ccaagcgcc 
      cccagcaca ccccccgaa gaacgtcac agtgcgggc 
      catgagcgc gactgaagt gagggttcg ctggattcc 
      tctgcagca aatcgaatg gttcgggaa cccgcgagg 
      gtactcgat tagttacgt ggaggtgcg aacggggga 
      aaaacagac ggcgacaat tgacgatca tacggccaa 
      ttcgcatgt gattaccgg attggagga gtttgcgtt 
      gtatgaagt gtccatgca ggcgtgcaa tgacgtggg 
      gtgttccat ggacgggcc cgtggcttt ggagaggac 
      cagggagtc agtaccatc gttcgggcc gttaaacat 
      cgaagcgaa cgctacctc tagcacaac aatcgtagt 
      gaaatgggg tgacgtccc gaaagaaca ccaaaacgg 
      cctaattga aggctacaa agtttatta cgccgccga 
      atcaaaatc gcccgtaca gtacaagct aatcgccag 
      caattccac ttttacaac cactttgac cgaattgcg 
      gaaattcgt cgtttaccg catccaggt cctggcgta 
      cacacggct cggcgacgg cgagcccag caaaccggc 
      cgtcagcgt gcgaacctt cgaagatgt cccgggccc 
      cccctcgaa tgtgtcatt cccggacgt ttccgtcac 
      ttcggccag gatcatctg ggacgtccc ggaagaacc 
      caacggcga aatcctggc gtacaaagt cacatatca 
      tatcgacaa cgtgaacgt taataataa atactcgaa 
      ggaatttcc gccgtctga tagaacgtt caggtttac 
      gcagttgga gcctgagaa gtattacat gttttctgt 
      gactgctca gaccagatt aggttgggg caagacagc 
      tcatgcttt ggtttttac aacgaataa tcgagacac 
      accacagtc accatctat gccacaaat cagtcgcag 
      tcaggtaca gagcaagca gatcacttt cagctggac 
      accgggcag agacggatt cgcaccgtt gagatatta 
      tacggtcca aaaaatgga aaatggggg cccttggca 
      gtcccttcc cgaacgtgt ggaccctca actcacctc 
      atacaccgt ctctgacct caaaccctt cacttcata 
      ccgcttcag aatccgcgc aacgaacga tataggtcc 
      cagcccctt cagtcccga atccatcga agtccgcac 
      ttatccagc agcccccag caaaggcgt catgaactt 
      aaaagtagt tcccataac aacgacaag tgtcgaagt 
      ctattggga cccagttga ggagaagta ctggaacgg 
      ggacgtcaa aacaggggg ctatagagt agtctttca 
      acccgtctc tgactatcc aactgcact gcaggcaac 
      acccaagga ggaaatttt cggaatcaa tgccaaaaa 
      aatggttct gagcgaatt attgcaaga caagaatta 
      tgagatagt tgtggtgcc gtttaattc gcaagggga 
      gggccccgc aacgccccc tgtcacagt gtatgtagg 
      ggaagccgt cccaactgg tgaaccaag ggacttgga 
      gggcgaagc tgtttcctc gacggaagt tcgcttgaa 
      atggaagcc gccacagca gcagcaaca aaacggcga 
      attgttggg atacaagat attttattt ggtgacaaa 
      ctcgccgca agattttga cgagggcca caagttcga 
      ggaggaaat cgaagtgat tgcagctac gatgacctc 
      gcacagcct tgtctttct cgacaaata caccgaata 
      tcgcataca aattctggc gtttaaccc agcaggtga 
      tggaccacg atcgcgccc catcacagt taagaccct 
      tcaaggtct ccctggtcc accagccaa tctacgctt 
      ttctgacat aacgatgaa tagcttgct cgtgtcgtg 
      ggatccccc gaaaaaacg caacggtga cataatcgg 
      ataccttgt cacgtatga gacgaccga ggagaacga 
      acgttttag taaacaagt caagcagaa agtgacgtc 
      gacggaact cttgctaca aactttgga ggaggaaat 
      cacttacac gttcacagt gcgggcaca aaccatcga 
      ttatgggcc ctctatttc ggataacgt caccacagg 
      gccacagga cggctcccc aacgacgcc aaaagaact 
      cactttgat taaaacacc gtcaagtgt ggagctgca 
      ctgggtcaa tggcttgac cggaaaggg gccaattct 
      gggctacta tatcgaatc gaggaaaaa agatgacca 
      gaggtggca aacagtcac gaaatcgac aaacgggcc 
      tttgcaaga atttacagt ttcgtacca aagtctcct 
      cccctcaac ctcttacta tttcagagt ttttcctta 
      caataaatt cggtattag ttgtcccgc gtacaccaa 
      agacccggt cgtaacacc gtcaaaact gtacttgga 
      atatagcta cttacagta tgaaccctt ctaccgaca 
      gacctggtt catggtcgc cctggcagc gacctccat 
      catcattat cataatgat aattgcgat tttgtgcgt 
      taagagcaa aagttacaa atataaaca agaaggtgc 
      ccaaaatag tatgggcga actcatggc aatgtcacg 
      cgacgacat gaccgctga ctattaccg aactcgcaa 
      cggcacaag taacctaag ctcgactct ttcaaaacg 
      tagcacttt atcccgcaa gccggtcca tcaacaacc 
      ccctccaat gttggggaa atcccctcc gagaccatc 
      gccggcttc agtgcccta caactcaga cgaggaaag 
      tctcaaggg ctacgatga gaatcccga cgatagcag 
      cgtgaccga gaagccgtc agaaatgag ctcttctga 
      atcccaggg ttcggaaag cgaaaacga cagtgtcct 
      ctcgaattc gcactcgtt tgtgaacca ctacgccaa 
      tgtgaacga gccattgcg accgtcctg gaagcgcca 
      aaagccggt caggaattt ctcgagtca cactgattc 
      ggaaccgga aggttcggc gagtttgaa tggaggaca 
      gattatcat taataacat ggcgaggtc aagggcgcc 
      cctacccgg attttcgtc gtttgttta atgatagct 
      gaattaaga aaatttgat aatgccact gttacttaa 
      gtatcagat tttcgtgat ctaggcaaa gacttgaca 
      tttttgtac atattttta attcaaagt ctattaagt 
      gattagagt cagacttac tatttgtat ataaaacct 
      gtaggactt tttactgta gataacgtt tcaaagcgc 
      atctattca cat
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