Status
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Gene information
General information
TC033570
Former TC numbers

If one gene is splitted or genes are merged, the original TC numbers are listed. One listed former TC number indicates the previous gene has be splitted, serveral former TC number represents a merged gene.

TC009576,TC009577,TC009575 		Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007422.5: 2788712..2815636
Sequence information
Transcripts / Proteins (1) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    		TC033570
    Gene ontology

    GO terms for Tribolium

    • {{ goTerm.term }}
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      Status: {{ goTerm.status }}
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      Reference: {{ goTerm.referenceText }}
      Quotation: {{ goTerm.quotation }}
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    There are no GO terms for Tribolium at the moment. You can help the community by providing some GO terms for this gene.


    GO terms for the homologous Drosophila genes

    Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term - use "graph views" to browse related terms ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.


    Gene
    {{ goGene }}
    The Tribolium gene the GO term is assigned to.
    GO ID *
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    The ID of the GO term you assign to the gene. Please enter only the ID of the GO term with proceeding 'GO:'. This information is mandatory.
    Evidence
    {{ blurEvidenceResult }}
    The evidence code describes with which method the function or location, expressed by the GO term, was show for this gene. Please refer to this page for a definition of the evidence code and a decision tree.
    Reference *
    {{ blurReferenceResult }}
    The reference where the function or location is described for the gene. Please enter a PubMed ID. This information is mandatory.
    Quotation
    If you paste here the relevant section of the reference it is for us a great help to review your annotation. The quotation may be also be displayed to the users of iBeetle-Base.
    Name
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    Email
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    Publish name
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    * : mandatory fields
    For help on how to submit larger datasets or non experimental data please contact us.
    iBeetle screen iB_04659

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 0.0% (includes death as pupa, adult)

    Analysis of embryonic musculature and early development
    number of eggs/embryos/larvae on slide: > 50 larval musculature mostlynot present - Penetrance (percentage of animals/eggs on slide): more than 80%

    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    remarks: muscle pattern potentially obscured by segmentation defect,
    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: > 50
     embryo/egg without visible larval cuticle in cuticle preparation - Penetrance (percentage of animals/eggs on slide): 30% - 50%
    larva everted (inside-out) - Penetrance (percentage of animals/eggs on slide): less than 30%

    larva segment dorsoventral-axis thinner - Penetrance (percentage of animals/eggs on slide): 30% - 50%

    head appendages sometimes shape irregular - Penetrance (percentage of animals/eggs on slide): 30% - 50%

    legs shape irregular - Penetrance (percentage of animals/eggs on slide): 30% - 50%
    legs shortened - Penetrance (percentage of animals/eggs on slide): 30% - 50%

    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 20.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 20.0% (includes death as larva, prepupa, pupa, adult)

    larva lethality - Number of animals showing the phenotype: 2 (11 dpi)
    Days post injection

    iBeetle screen iB_06274

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 30.0% (includes death as pupa, adult)

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 2 (3 dpi)
    Days post injection

    adult lethality - Number of animals showing the phenotype: 1 (9 dpi)
    Days post injection

    Analysis of embryonic musculature and early development
    number of eggs/embryos/larvae on slide: > 50 embryo/egg with embryonic tissue, no cuticle, no fluorescence - Penetrance (percentage of animals/eggs on slide): 30% - 50%

    larval musculature pattern irregular - Penetrance (percentage of animals/eggs on slide): 50% - 80%

    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    remarks: muscle pattern potentially obscured by segmentation defect,
    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: > 50
     embryo/egg without visible larval cuticle in cuticle preparation - Penetrance (percentage of animals/eggs on slide): 30% - 50%
    legs size decreased - Penetrance (percentage of animals/eggs on slide): 50% - 80%

    Comment: Femur and Tibiotarsus potentially fused.
    legs shape irregular - Penetrance (percentage of animals/eggs on slide): 50% - 80%
    thorax circumference irregular - Penetrance (percentage of animals/eggs on slide): 30% - 50%
    thorax circumference thinner - Penetrance (percentage of animals/eggs on slide): 50% - 80%

    abdomen segment number decreased -

    abdomen circumference irregular - Penetrance (percentage of animals/eggs on slide): 30% - 50%
    abdomen circumference thinner - Penetrance (percentage of animals/eggs on slide): 50% - 80%
    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 20.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 20.0% (includes death as larva, prepupa, pupa, adult)

    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC033570 RA
      MMGIPASGP ALKECPCEE VDVGFECRC SGPALMDIP 
NSLHKELTI LVIEDAGIE VLKSDSLVP YSSTLRELY 
IHRAPKLLK IQPEVFSAY LPNLKILRI VNTGLEEMP 
NFNGLNTSS VLHMIDLEH NRIQRINTR QISRVKAEQ 
LVLNYNDLQ VVEEAAFAG SQIAKLSLS GNFRLKNLH 
VKAFHGLES LRYIDLSST AITALPVEG LREIDVLKV 
QDTESLKVF PSVYNFKYI KEAWLTYPY HCCAFKFPH 
THNPWEYER HNRFVKQQR QACTAKNAK NADPTLRAL 
FRAIPPNAS LAESDFDEQ WNGDEIFHN STMNLNNGS 
PVTTAVCGE IYRNYHEVK CHPAPDAFN PCEDLMGNW 
ALRIPVWFI SLSAVIGNL FVVIVISTS HFRLTVSKF 
LMCNLAVAD LCIGIHLLL IAVVDACSI RAYFNYAID 
WQEGNGCRV AGTLTIFGN VLSVYTLAV ITTERWYTI 
TWAIHLNKR LKLRTAVRV MIAGWICAL FMACLPLVG 
VSSYSKTSI CLPLENKGK ADTIYLSTL LAFNAIAFA 
LICVCYGSM YKSIREGGH TGSTTSVRS DLTVAKRMA 
LLVFTDFAC WAPIAFFSL TALLGHPLI TVTQTKILL 
VFFYPLNSC ANPCLYALL TQQYRRDFF ILMGRYGLC 
KDRAERHKG AIGGKPLPY GSGPQYKRT SGEAAGKIH 
SAGGNNHRG SLLTTIVSV EVPMVRTSS RNSARSRPD 
SLNAVPEYS LQQINLGMM DDCRKLTST DNFCLSQQS 
DTCYQTKPF LLLISECFF PQCLIPTRP DMDQLITSL 
DKLLKYKNE DPSRFYTFL SDCTETDEK QWESLIPKI 
YYLYDRQVL RKDLVYLSL LASQNHALL RKFVDYDKS 
IYVLNVADP VSLYDYYVY KGKHWVYEI IDNPGNHAK 
LVDLKNIYN KFQMIKYVK ETNTSVVDL DQLERLSHA 
INFEFLDDF WKFYVAEIT RFITTVKFC KTLKPDAND 
SDLFVFASK NTQLDTLSR FTDLSDATQ WENILAKLC 
NNCDQFNIF TGFVILATL INLLIDNYN TNLKKDHVN 
ALFETVKTK LIDLKDKQL QIELLENIF RLMFHRKSH 
EFTCKEKEI RFVLFLLKS VTEELKLKK VYERDSEHY 
RRLSTLSIY VTDALWRLD LILNTKNTP KIQEQLLNY 
MLAPPESLI HICLKRHNF ERAHQVIEI FDLRDSDLA 
QQVNYSETF LKFRKFLRK NGKLAQTVT EFFESNSPN 
EIFTNIFDL AITGTQTWD ESEILLNLA EKFNSDETL 
PSSYLNFYK RVTEIGHEV GPKDNISLP QILISPNYP 
LDVNVYKTK VEFFQNLAR LYDEFNGQN RPNEPGSFN 
KNHPNHKTL LKMNELIVN YLQDRDTTQ YLARIFNYL 
KAFSKILYI EQNSSDIIS KGKNSSYFD IFNFNRSEL 
TGKLLFERQ LDPTEFEKY FGKLKLDFL YHVVGNCFP 
TINLHVQEN VTIEELYHD NMLYIPSRS IIVYIQKRN 
WLLAFILNE MYKVEGVKI DISEVRLRT FFNYLKSPR 
IQHLKALFD KNDIIAALQ NCINAQKVK LYFRERIIE 
HDLVSIQSQ NSSNSDGFE TGEEIQEDA KTTNWRTLY 
DIIESIPEN QMKKKSDLI ICKDNVLVN MVQDGFEPE 
YYKYAHFIT NRDLRIDTI LSNFRKWPG KFAADIIKS 
EISRFDCLM DSKMETLCG WLQQIELNE ELKSVFEVK 
SWYKSYAFC KEVPESALE KILLTNNVD FLLDFVQLY 
QPSPETVCK INSSYLTRI MDTNIPLDR IKKLLDSLP 
FEHAIDMCH NLLTILHNL EYLQFIADY LSTNVSDDL 
FLKNVQISL KMLSVFTPL EQDQLFCLI NEPLSILEV 
LLMNTKLDK LAAILDLLN AHNLSDFSE VITTEKIDE 
LLRKYAEKS LDFRVITHP NPGLFKTPE PKLLQSLDS 
LSLMSDKRQ FVVPENVPT KEEWVQNDE VVECMCCHQ 
VTFSMFNRR HHCRRCGRV VCYNCSLKR MFVPTYGDI 
LVRVCSDCY NQTVGERND SNSDKSRSF IQEYWLLND 
DPEHNKIIR EEFSYEHAP STSLCFSIL RYHSKSIEY 
PKFLLEQCE VMLKLLQPN QEAAQEIDY LLVIKMLKS 
LAMAAKMVS TENMLQSGA SMADRILSQ AELLALLAE 
RGCLNLMPS QNLYVDANV LRRLRDKLL QREQWNLAL 
EVSTKAGLD NTGVFAAWS KSCLKAGSL LLAREKFQR 
CLDKNSQYE TSSNLSRLS ELNSSLDSL SLSRSRMSS 
RFSSGSFTL DNKPAKDPP LLYEIIQIL ETKTRTINP 
KVVEKAQSI KISGSVTSL NQISSSYTV HIDTALSIV 
NRVKNLKEI ASGNYSLTA SKKFNCYTS RPTIDPIFY 
EECIYYLGK YGTHLSLLE FYIRHGEIH TALIYILEC 
HLPSETFIE VYMKCLKDG IVTILQEHM SRIDSSLEL 
WKDHLKNLC RHLEKQQLL NCLYQLQLY IGDYVRASM 
TCIRFYQDN VKSFTELAN NVGFLHKGE GHLRQILEQ 
EQWVEVTSV TSKDSFEER LLTNSDLVM KIESKDVNR 
HINTVKRQV EIVKFLADC EAAGVNTRD LLRQLVLTK 
DPKAEQQVA IPTLFGTTL EKINLAVMA IISGETVED 
GFNLATKII EDFKLRPIK VYCLAGKQF AKSERYNGI 
TQLVNCIKS TGINDSAIS DMLDEMLAH AVGTLIKEN 
IEGTKVEDL IKLINDKAT KISAYIEAK QLKTAYFLA 
VKYKRTADI RRIQREAEL LNMPTIKAL CQKVLQNSP 
HTHSKD
    CDS sequence
    • >TC033570 RA
      atgatgggc atccccgcc agcgggccg gccctgaaa 
gagtgtccc tgcgaggaa gtggacgtg gggtttgaa 
tgcagatgc agcggtccg gccctgatg gacatcccc 
aacagcctg cataaagag ctcaccatt ctggttatc 
gaggacgcc gggattgaa gtgctgaaa agcgattcg 
ctcgtgccc tactcgagc acgctgcga gagctatac 
atccaccgc gcccccaaa ctcctgaaa atccagccg 
gaggttttc agcgcttac ctccccaac ctcaagatc 
ttgaggatc gtcaacacg ggattagag gaaatgccg 
aacttcaac ggattgaac acttcctcg gtgttgcac 
atgatagat ttggagcat aaccgcatc cagagaatc 
aacacgcgg caaattagc agagtcaag gctgagcaa 
ctagtgctc aactacaac gatttgcaa gtggtcgaa 
gaggcggca tttgcgggc tcgcagatc gctaaatta 
agcctgagt ggaaatttt cgactgaaa aacctccac 
gtgaaggcg tttcacgga ctggagagc ttgcgctac 
atcgacctc tcaagcact gccataacg gcgttaccc 
gtggaaggc ctgcgggaa atcgacgtc ctcaaagtc 
caagacaca gagtcgctt aaagtcttt ccctcagtt 
tacaacttc aagtacata aaagaagcc tggctgacc 
tacccttac cattgttgc gccttcaag ttcccccac 
acccacaac ccctgggag tacgaaaga cacaaccga 
tttgtcaag cagcagcgc caagcttgc accgccaaa 
aacgccaaa aacgctgac ccgactctg agggcgctg 
tttagggcc attccgccg aatgcaagt ctcgctgag 
agcgatttt gacgagcag tggaacggc gatgagatt 
tttcacaac agtacgatg aatctgaat aatggatcg 
ccggttact accgccgtt tgtggagag atatacagg 
aattatcac gaggtcaag tgtcatcca gcgccggac 
gccttcaac ccctgcgaa gacctgatg ggaaattgg 
gctttaagg ataccggta tggttcata tcgttatcg 
gcagtgatc ggaaatctg ttcgtggta atagtcatc 
tcgacatcg cattttcga ctgacagtt tcgaaattt 
ctcatgtgc aatttagcc gtggctgat ttatgcatc 
ggcatccat ctgctgctt attgccgtg gtggacgcc 
tgctccata agggcctat ttcaattac gccatcgat 
tggcaagaa ggcaacggc tgtcgcgtt gccggcacg 
ctcaccatc ttcggcaac gtcctctcg gtgtacacc 
ctcgctgtg ataaccacc gagcgatgg tacaccatc 
acctgggcc atccatctc aacaagcgc ctaaagctc 
cggacggca gttcgcgtg atgatcgcc ggctggatt 
tgtgccctt tttatggca tgtctcccc cttgtgggg 
gtgagcagc tactccaaa acgagcata tgtctgccc 
ttggagaac aaaggcaaa gccgacacg atatatctc 
tccactttg ctcgctttc aacgcgatc gcgttcgcc 
ctcatctgc gtctgctac ggaagtatg tacaagtcg 
attcgtgag ggtggacac acgggatct acgacttcc 
gtccggtcc gacctcact gtggccaag aggatggct 
ttgctcgtc ttcaccgat tttgcgtgc tgggcgccg 
atcgccttc ttcagcctc acggcgctt ttaggccat 
ccgttgatc accgtcacg cagacgaag atcctcctc 
gtgttcttc tacccgctc aactcgtgc gccaacccc 
tgtctgtac gccctgctg acgcagcaa taccgccgc 
gactttttc atcttaatg gggcgctac ggcctgtgc 
aaggaccgc gccgagcgc cacaagggg gccatcggg 
ggcaaaccg ctcccgtac ggctccggc ccgcagtat 
aagcggact agcggcgag gcagccggc aaaattcac 
agtgcggga ggtaacaac catcgaggg tctcttttg 
accactatc gtttcagta gaagtgccc atggtgagg 
actagttcc cggaacagt gcgcgctcg cgcccggac 
tcgctcaac gccgttccg gagtattcc ctccagcaa 
atcaacctc ggcatgatg gacgattgc cggaaactc 
acttcgacc gataacttc tgtttgtca caacaaagt 
gacacatgt tatcaaaca aaacctttt ttattatta 
atcagtgaa tgctttttt ccgcaatgt ttaatcccg 
actcgacct gacatggat cagttaatt acgagcctt 
gataagctc ctgaaatac aaaaacgag gatccctcc 
cgtttttac accttcttg agcgattgc accgaaacc 
gatgaaaaa caatgggaa agtttgata cctaaaatt 
tactatctg tatgataga caagtttta cgcaaagat 
ctcgtttat ctttcattg ttggcgagc cagaatcac 
gctctttta cggaaattt gttgattac gataagtct 
atttacgtt ttaaatgtt gccgatcca gtctcgctt 
tacgattat tatgtttac aaggggaaa cactgggtt 
tatgagata atagacaat ccgggcaat catgcgaaa 
cttgttgat ttgaaaaat atttacaat aaattccaa 
atgataaaa tacgttaaa gagacaaac acgtctgtt 
gttgacctc gaccagctt gagcgtctc tcccacgca 
ataaatttc gagtttttg gacgatttt tggaaattt 
tacgtcgcc gagataacg cgatttatc acaacagta 
aagttttgt aaaactctc aaaccggat gcaaacgat 
tcagattta tttgttttc gcgagtaaa aacacacaa 
cttgatact ttatcgcgt ttcaccgac ttgagcgat 
gccacacaa tgggaaaac atcttagct aaactatgc 
aataattgc gaccaattt aacattttc accggcttt 
gtgatactc gcgactttg atcaatctc ctaatagac 
aattacaac accaatttg aaaaaagat cacgtcaat 
gccctcttc gaaaccgtc aaaaccaaa ctcatcgac 
ttaaaagac aagcaatta cagatcgaa ttactcgag 
aatattttc cgcttgatg tttcaccga aagtcgcac 
gaattcact tgcaaagag aaagaaatc cgcttcgtt 
ttgttttta ctaaagtca gtaacagag gaattaaaa 
ttgaaaaaa gtctacgaa cgcgactcc gaacactat 
cgaagactc tcaactctc tcgatttac gtaacggac 
gccttgtgg cgtctcgac ttgatcctc aacacaaaa 
aacacccca aaaatacaa gaacaactc ctcaactac 
atgctcgca cctccggag tccctcatc cacatctgc 
ctcaaacgg cacaacttc gaacgcgcc caccaggtg 
atagagatt ttcgatctg agggactct gatctcgcg 
caacaagtc aactactcg gaaactttc ctcaaattc 
aggaaattc ctccgaaaa aacggcaaa ttggcgcaa 
acagtcacc gaatttttc gaatcaaat tcgccaaac 
gaaattttt acgaatatt ttcgatctt gcaatcacc 
ggaacccaa acgtgggac gaatcagaa attttgcta 
aacctagcc gaaaaattc aattccgac gaaacgctc 
ccttctagt tatctcaat ttctacaaa cgagtgacg 
gaaattggg cacgaagtg ggccccaaa gacaacatt 
tcactgccc cagattcta atttcccca aactatccc 
ttggatgtt aacgtctac aaaaccaaa gtggaattt 
ttccaaaac ttggcccga ctttatgac gaatttaac 
ggtcaaaac cgccctaat gaacccggg agtttcaat 
aaaaaccac ccaaatcac aaaaccttg ctcaaaatg 
aacgaactg atcgttaat tacctccaa gatcgggac 
acaacgcaa tacctcgcc cgcattttc aattacttg 
aaagccttt tcgaaaatt ttgtacatc gagcagaac 
agttcggac atcatttcg aagggaaaa aactcgtct 
tacttcgac attttcaac ttcaaccgc tcggaattg 
accgggaaa ttgctgttc gagcgtcag ctggacccg 
actgagttt gaaaaatac ttcgggaaa ctcaagttg 
gattttttg taccacgtg gtggggaat tgcttcccg 
acgattaat ctccacgtg caggaaaat gtgaccatt 
gaagagctg taccatgat aacatgttg tacattccg 
agccgcagc ataattgtg tacatccag aaacgcaac 
tggttgctt gcctttatc ctgaacgag atgtacaaa 
gttgaagga gtcaaaatc gatattagc gaagttcgc 
ttaaggacg ttctttaat tatttaaaa tcgcccaga 
atccagcac ttgaaggcg cttttcgac aaaaacgac 
atcatcgca gcgctccag aactgcata aatgcccaa 
aaagtcaag ttatatttc cgcgaacgc attatcgag 
catgatcta gtctcgatc cagtcgcaa aacagcagc 
aattctgac ggttttgaa accggggaa gagattcaa 
gaagacgca aaaacgacc aactggaga accctctac 
gatattatc gaaagcatt ccggaaaat cagatgaag 
aaaaagtca gacttgatc atttgcaag gacaatgtt 
ctggttaac atggtgcaa gacgggttc gagcccgaa 
tattacaaa tacgctcat tttattaca aacagggac 
ttgcggatt gacacgatt ttgagcaat tttaggaaa 
tggccgggg aaattcgcc gctgatata atcaaaagt 
gagattagt agattcgat tgtttgatg gattcgaaa 
atggagacg ttgtgtggt tggttgcaa caaattgag 
ctcaacgaa gagctgaaa agcgttttt gaggtgaaa 
tcgtggtac aagagctac gctttttgc aaggaggtg 
cccgaaagc gcccttgaa aaaatcctg ctaacgaat 
aatgtggac tttttgctg gacttcgtc cagttgtac 
caaccctcg cccgaaacc gtctgcaaa atcaattcg 
agttactta acccgaata atggacacg aacattcca 
ctcgaccgg ataaaaaaa ctgctcgat agtctaccc 
ttcgagcac gccatagac atgtgccat aacttactc 
acaatctta cacaacttg gaatatcta caattcatc 
gccgattat ctaagcacc aacgtttcg gacgactta 
ttcctaaag aacgtccaa atcagtttg aaaatgctc 
tcggtcttc acaccactc gagcaagac caacttttc 
tgtctcata aacgaacct ttgagcatc ctcgaagtg 
ctcctaatg aacacaaaa ctggacaaa ctcgcggct 
attttagac ttgctaaac gcccacaat ttaagcgac 
tttagcgag gttataacc acagagaaa atcgacgaa 
ttgttgcgg aaatacgcc gagaagagc ttggatttt 
cgcgttatc acgcaccct aatcccggc ttatttaaa 
acaccggag ccgaaatta ttacaatcg ttggactcg 
cttagttta atgtccgat aaacgccag tttgtcgtc 
cctgaaaac gtcccaact aaggaagag tgggttcaa 
aacgacgaa gtcgtcgag tgcatgtgt tgccaccag 
gtcactttt tccatgttc aatcggcgg caccactgt 
cggagatgt ggccgcgtt gtttgttac aattgttcc 
ttgaaacgc atgttcgtg cccacttat ggcgacatt 
ctagtgaga gtttgctcc gactgttat aatcagaca 
gtcggggag agaaacgac agcaattcg gacaaaagc 
cgctccttt atacaggaa tattggctc ttgaacgac 
gaccccgaa cataataaa atcataaga gaggagttc 
tcctacgaa cacgcccct agcacctct ctgtgtttc 
tcaatcctg agatatcac tccaaaagt atcgaatat 
cccaagttt ttattagag cagtgtgaa gtcatgttg 
aagttattg caaccgaat caagaggcg gcccaagaa 
attgactat ctcctcgtt ataaaaatg ttaaagtca 
ctcgctatg gcggccaag atggtctcg actgaaaat 
atgctccaa tcgggtgct tccatggcc gaccggatt 
ctctcacag gccgaactt ttggccctt ttggcagaa 
cgcggctgt ttgaatctt atgccgagt caaaatctt 
tacgtcgat gctaatgtt ttgcgccga ttgcgagat 
aaattgcta cagagggag cagtggaat ttggccctg 
gaggtgtcc accaaagcg ggactcgac aataccggg 
gtttttgcc gcctggagc aagagctgc cttaaggcg 
ggcagcctg ctcctagcc cgcgaaaag ttccaacgc 
tgccttgac aagaacagc caatacgaa acctcgtca 
aatttgagc cgactttcc gagctcaat tcgagttta 
gatagtttg agtttgagt cgatctcgg atgagttca 
cgattctca agcggaagt ttcacctta gacaataaa 
ccagctaaa gatccgccc ctcttgtac gaaatcatc 
caaattttg gaaaccaaa acgcggact ataaacccg 
aaagttgtc gaaaaagcc caaagtatc aagatttca 
ggctcggtc acgagcctc aaccaaata tcatcatcg 
tacaccgtg cacattgac acagcctta agcatcgta 
aaccgggtc aaaaatttg aaagaaatc gcatcgggg 
aattactca ctgaccgca agcaaaaaa ttcaattgt 
tacactagt cggcccaca atcgacccg attttttac 
gaggaatgt atctattat ttgggcaaa tacgggacg 
catttatcg ctactggag ttttatatc aggcatggg 
gaaatccac actgccctc atatacata ctcgagtgc 
catctaccg agcgaaacc ttcatcgaa gtctatatg 
aagtgcctt aaagacggg atcgtaaca attttgcaa 
gagcacatg tcacggatc gactcatcg ctcgaactg 
tggaaagac cacttgaag aatttgtgt cgccacttg 
gagaagcaa caattattg aactgtttg taccagttg 
cagctgtac atcggcgac tatgtgcgc gcttcgatg 
acttgtatc cgattctac caagacaac gtgaaaagt 
ttcacagaa cttgcgaac aatgtcggc tttttgcac 
aagggcgag gggcatttg aggcagatt ttggagcag 
gagcagtgg gtggaggtg acttcggtc acttccaag 
gatagtttc gaggagaga ctcttgacc aattcggac 
ttggtcatg aaaatcgag tcgaaagac gtcaaccga 
cacataaat acagtaaaa cgacaggtg gaaattgtg 
aaatttttg gccgattgt gaggcggca ggggtcaac 
acgcgcgac ctgcttcgg cagctggtt ttgaccaaa 
gatcctaaa gccgagcag caagtggcg attccgacc 
ctcttcggc acgactttg gagaagatc aatttggct 
gtgatggct ataattagt ggcgaaacg gtcgaggac 
gggtttaat ttagccaca aagatcatt gaggacttt 
aaattaaga ccgatcaag gtttattgt ttagctggg 
aaacagttt gcgaaatct gagcgctat aacggaata 
acgcagtta gttaactgt atcaaatca acaggaatt 
aacgattca gctatttcg gatatgttg gatgaaatg 
ctagcgcac gctgtgggg actttgatc aaggaaaac 
atcgaaggg accaaagtc gaggacttg atcaaactt 
attaacgat aaggctacg aagatctct gcatatatt 
gaagccaaa cagttaaaa acggcgtat ttcctggcc 
gttaagtac aaacgaacg gctgatatt aggaggatt 
cagagggag gctgagttg ttaaatatg ccaacaatt 
aaggccctg tgccagaag gtgctgcaa aactcgcca 
cacacgcat tccaaagac taa
    mRNA sequence
    • >TC033570 RA
      cgacaaaat catgatggg catccccgc cagcgggcc 
ggccctgaa agagtgtcc ctgcgagga agtggacgt 
ggggtttga atgcagatg cagcggtcc ggccctgat 
ggacatccc caacagcct gcataaaga gctcaccat 
tctggttat cgaggacgc cgggattga agtgctgaa 
aagcgattc gctcgtgcc ctactcgag cacgctgcg 
agagctata catccaccg cgcccccaa actcctgaa 
aatccagcc ggaggtttt cagcgctta cctccccaa 
cctcaagat cttgaggat cgtcaacac gggattaga 
ggaaatgcc gaacttcaa cggattgaa cacttcctc 
ggtgttgca catgataga tttggagca taaccgcat 
ccagagaat caacacgcg gcaaattag cagagtcaa 
ggctgagca actagtgct caactacaa cgatttgca 
agtggtcga agaggcggc atttgcggg ctcgcagat 
cgctaaatt aagcctgag tggaaattt tcgactgaa 
aaacctcca cgtgaaggc gtttcacgg actggagag 
cttgcgcta catcgacct ctcaagcac tgccataac 
ggcgttacc cgtggaagg cctgcggga aatcgacgt 
cctcaaagt ccaagacac agagtcgct taaagtctt 
tccctcagt ttacaactt caagtacat aaaagaagc 
ctggctgac ctaccctta ccattgttg cgccttcaa 
gttccccca cacccacaa cccctggga gtacgaaag 
acacaaccg atttgtcaa gcagcagcg ccaagcttg 
caccgccaa aaacgccaa aaacgctga cccgactct 
gagggcgct gtttagggc cattccgcc gaatgcaag 
tctcgctga gagcgattt tgacgagca gtggaacgg 
cgatgagat ttttcacaa cagtacgat gaatctgaa 
taatggatc gccggttac taccgccgt ttgtggaga 
gatatacag gaattatca cgaggtcaa gtgtcatcc 
agcgccgga cgccttcaa cccctgcga agacctgat 
gggaaattg ggctttaag gataccggt atggttcat 
atcgttatc ggcagtgat cggaaatct gttcgtggt 
aatagtcat ctcgacatc gcattttcg actgacagt 
ttcgaaatt tctcatgtg caatttagc cgtggctga 
tttatgcat cggcatcca tctgctgct tattgccgt 
ggtggacgc ctgctccat aagggccta tttcaatta 
cgccatcga ttggcaaga aggcaacgg ctgtcgcgt 
tgccggcac gctcaccat cttcggcaa cgtcctctc 
ggtgtacac cctcgctgt gataaccac cgagcgatg 
gtacaccat cacctgggc catccatct caacaagcg 
cctaaagct ccggacggc agttcgcgt gatgatcgc 
cggctggat ttgtgccct ttttatggc atgtctccc 
ccttgtggg ggtgagcag ctactccaa aacgagcat 
atgtctgcc cttggagaa caaaggcaa agccgacac 
gatatatct ctccacttt gctcgcttt caacgcgat 
cgcgttcgc cctcatctg cgtctgcta cggaagtat 
gtacaagtc gattcgtga gggtggaca cacgggatc 
tacgacttc cgtccggtc cgacctcac tgtggccaa 
gaggatggc tttgctcgt cttcaccga ttttgcgtg 
ctgggcgcc gatcgcctt cttcagcct cacggcgct 
tttaggcca tccgttgat caccgtcac gcagacgaa 
gatcctcct cgtgttctt ctacccgct caactcgtg 
cgccaaccc ctgtctgta cgccctgct gacgcagca 
ataccgccg cgacttttt catcttaat ggggcgcta 
cggcctgtg caaggaccg cgccgagcg ccacaaggg 
ggccatcgg gggcaaacc gctcccgta cggctccgg 
cccgcagta taagcggac tagcggcga ggcagccgg 
caaaattca cagtgcggg aggtaacaa ccatcgagg 
gtctctttt gaccactat cgtttcagt agaagtgcc 
catggtgag gactagttc ccggaacag tgcgcgctc 
gcgcccgga ctcgctcaa cgccgttcc ggagtattc 
cctccagca aatcaacct cggcatgat ggacgattg 
ccggaaact cacttcgac cgataactt ctgtttgtc 
acaacaaag tgacacatg ttatcaaac aaaaccttt 
tttattatt aatcagtga atgcttttt tccgcaatg 
tttaatccc gactcgacc tgacatgga tcagttaat 
tacgagcct tgataagct cctgaaata caaaaacga 
ggatccctc ccgttttta caccttctt gagcgattg 
caccgaaac cgatgaaaa acaatggga aagtttgat 
acctaaaat ttactatct gtatgatag acaagtttt 
acgcaaaga tctcgttta tctttcatt gttggcgag 
ccagaatca cgctctttt acggaaatt tgttgatta 
cgataagtc tatttacgt tttaaatgt tgccgatcc 
agtctcgct ttacgatta ttatgttta caaggggaa 
acactgggt ttatgagat aatagacaa tccgggcaa 
tcatgcgaa acttgttga tttgaaaaa tatttacaa 
taaattcca aatgataaa atacgttaa agagacaaa 
cacgtctgt tgttgacct cgaccagct tgagcgtct 
ctcccacgc aataaattt cgagttttt ggacgattt 
ttggaaatt ttacgtcgc cgagataac gcgatttat 
cacaacagt aaagttttg taaaactct caaaccgga 
tgcaaacga ttcagattt atttgtttt cgcgagtaa 
aaacacaca acttgatac tttatcgcg tttcaccga 
cttgagcga tgccacaca atgggaaaa catcttagc 
taaactatg caataattg cgaccaatt taacatttt 
caccggctt tgtgatact cgcgacttt gatcaatct 
cctaataga caattacaa caccaattt gaaaaaaga 
tcacgtcaa tgccctctt cgaaaccgt caaaaccaa 
actcatcga cttaaaaga caagcaatt acagatcga 
attactcga gaatatttt ccgcttgat gtttcaccg 
aaagtcgca cgaattcac ttgcaaaga gaaagaaat 
ccgcttcgt tttgttttt actaaagtc agtaacaga 
ggaattaaa attgaaaaa agtctacga acgcgactc 
cgaacacta tcgaagact ctcaactct ctcgattta 
cgtaacgga cgccttgtg gcgtctcga cttgatcct 
caacacaaa aaacacccc aaaaataca agaacaact 
cctcaacta catgctcgc acctccgga gtccctcat 
ccacatctg cctcaaacg gcacaactt cgaacgcgc 
ccaccaggt gatagagat tttcgatct gagggactc 
tgatctcgc gcaacaagt caactactc ggaaacttt 
cctcaaatt caggaaatt cctccgaaa aaacggcaa 
attggcgca aacagtcac cgaattttt cgaatcaaa 
ttcgccaaa cgaaatttt tacgaatat tttcgatct 
tgcaatcac cggaaccca aacgtggga cgaatcaga 
aattttgct aaacctagc cgaaaaatt caattccga 
cgaaacgct cccttctag ttatctcaa tttctacaa 
acgagtgac ggaaattgg gcacgaagt gggccccaa 
agacaacat ttcactgcc ccagattct aatttcccc 
aaactatcc cttggatgt taacgtcta caaaaccaa 
agtggaatt tttccaaaa cttggcccg actttatga 
cgaatttaa cggtcaaaa ccgccctaa tgaacccgg 
gagtttcaa taaaaacca cccaaatca caaaacctt 
gctcaaaat gaacgaact gatcgttaa ttacctcca 
agatcggga cacaacgca atacctcgc ccgcatttt 
caattactt gaaagcctt ttcgaaaat tttgtacat 
cgagcagaa cagttcgga catcatttc gaagggaaa 
aaactcgtc ttacttcga cattttcaa cttcaaccg 
ctcggaatt gaccgggaa attgctgtt cgagcgtca 
gctggaccc gactgagtt tgaaaaata cttcgggaa 
actcaagtt ggatttttt gtaccacgt ggtggggaa 
ttgcttccc gacgattaa tctccacgt gcaggaaaa 
tgtgaccat tgaagagct gtaccatga taacatgtt 
gtacattcc gagccgcag cataattgt gtacatcca 
gaaacgcaa ctggttgct tgcctttat cctgaacga 
gatgtacaa agttgaagg agtcaaaat cgatattag 
cgaagttcg cttaaggac gttctttaa ttatttaaa 
atcgcccag aatccagca cttgaaggc gcttttcga 
caaaaacga catcatcgc agcgctcca gaactgcat 
aaatgccca aaaagtcaa gttatattt ccgcgaacg 
cattatcga gcatgatct agtctcgat ccagtcgca 
aaacagcag caattctga cggttttga aaccgggga 
agagattca agaagacgc aaaaacgac caactggag 
aaccctcta cgatattat cgaaagcat tccggaaaa 
tcagatgaa gaaaaagtc agacttgat catttgcaa 
ggacaatgt tctggttaa catggtgca agacgggtt 
cgagcccga atattacaa atacgctca ttttattac 
aaacaggga cttgcggat tgacacgat tttgagcaa 
ttttaggaa atggccggg gaaattcgc cgctgatat 
aatcaaaag tgagattag tagattcga ttgtttgat 
ggattcgaa aatggagac gttgtgtgg ttggttgca 
acaaattga gctcaacga agagctgaa aagcgtttt 
tgaggtgaa atcgtggta caagagcta cgctttttg 
caaggaggt gcccgaaag cgcccttga aaaaatcct 
gctaacgaa taatgtgga ctttttgct ggacttcgt 
ccagttgta ccaaccctc gcccgaaac cgtctgcaa 
aatcaattc gagttactt aacccgaat aatggacac 
gaacattcc actcgaccg gataaaaaa actgctcga 
tagtctacc cttcgagca cgccataga catgtgcca 
taacttact cacaatctt acacaactt ggaatatct 
acaattcat cgccgatta tctaagcac caacgtttc 
ggacgactt attcctaaa gaacgtcca aatcagttt 
gaaaatgct ctcggtctt cacaccact cgagcaaga 
ccaactttt ctgtctcat aaacgaacc tttgagcat 
cctcgaagt gctcctaat gaacacaaa actggacaa 
actcgcggc tattttaga cttgctaaa cgcccacaa 
tttaagcga ctttagcga ggttataac cacagagaa 
aatcgacga attgttgcg gaaatacgc cgagaagag 
cttggattt tcgcgttat cacgcaccc taatcccgg 
cttatttaa aacaccgga gccgaaatt attacaatc 
gttggactc gcttagttt aatgtccga taaacgcca 
gtttgtcgt ccctgaaaa cgtcccaac taaggaaga 
gtgggttca aaacgacga agtcgtcga gtgcatgtg 
ttgccacca ggtcacttt ttccatgtt caatcggcg 
gcaccactg tcggagatg tggccgcgt tgtttgtta 
caattgttc cttgaaacg catgttcgt gcccactta 
tggcgacat tctagtgag agtttgctc cgactgtta 
taatcagac agtcgggga gagaaacga cagcaattc 
ggacaaaag ccgctcctt tatacagga atattggct 
cttgaacga cgaccccga acataataa aatcataag 
agaggagtt ctcctacga acacgcccc tagcacctc 
tctgtgttt ctcaatcct gagatatca ctccaaaag 
tatcgaata tcccaagtt tttattaga gcagtgtga 
agtcatgtt gaagttatt gcaaccgaa tcaagaggc 
ggcccaaga aattgacta tctcctcgt tataaaaat 
gttaaagtc actcgctat ggcggccaa gatggtctc 
gactgaaaa tatgctcca atcgggtgc ttccatggc 
cgaccggat tctctcaca ggccgaact tttggccct 
tttggcaga acgcggctg tttgaatct tatgccgag 
tcaaaatct ttacgtcga tgctaatgt tttgcgccg 
attgcgaga taaattgct acagaggga gcagtggaa 
tttggccct ggaggtgtc caccaaagc gggactcga 
caataccgg ggtttttgc cgcctggag caagagctg 
ccttaaggc gggcagcct gctcctagc ccgcgaaaa 
gttccaacg ctgccttga caagaacag ccaatacga 
aacctcgtc aaatttgag ccgactttc cgagctcaa 
ttcgagttt agatagttt gagtttgag tcgatctcg 
gatgagttc acgattctc aagcggaag tttcacctt 
agacaataa accagctaa agatccgcc cctcttgta 
cgaaatcat ccaaatttt ggaaaccaa aacgcggac 
tataaaccc gaaagttgt cgaaaaagc ccaaagtat 
caagatttc aggctcggt cacgagcct caaccaaat 
atcatcatc gtacaccgt gcacattga cacagcctt 
aagcatcgt aaaccgggt caaaaattt gaaagaaat 
cgcatcggg gaattactc actgaccgc aagcaaaaa 
attcaattg ttacactag tcggcccac aatcgaccc 
gatttttta cgaggaatg tatctatta tttgggcaa 
atacgggac gcatttatc gctactgga gttttatat 
caggcatgg ggaaatcca cactgccct catatacat 
actcgagtg ccatctacc gagcgaaac cttcatcga 
agtctatat gaagtgcct taaagacgg gatcgtaac 
aattttgca agagcacat gtcacggat cgactcatc 
gctcgaact gtggaaaga ccacttgaa gaatttgtg 
tcgccactt ggagaagca acaattatt gaactgttt 
gtaccagtt gcagctgta catcggcga ctatgtgcg 
cgcttcgat gacttgtat ccgattcta ccaagacaa 
cgtgaaaag tttcacaga acttgcgaa caatgtcgg 
ctttttgca caagggcga ggggcattt gaggcagat 
tttggagca ggagcagtg ggtggaggt gacttcggt 
cacttccaa ggatagttt cgaggagag actcttgac 
caattcgga cttggtcat gaaaatcga gtcgaaaga 
cgtcaaccg acacataaa tacagtaaa acgacaggt 
ggaaattgt gaaattttt ggccgattg tgaggcggc 
aggggtcaa cacgcgcga cctgcttcg gcagctggt 
tttgaccaa agatcctaa agccgagca gcaagtggc 
gattccgac cctcttcgg cacgacttt ggagaagat 
caatttggc tgtgatggc tataattag tggcgaaac 
ggtcgagga cgggtttaa tttagccac aaagatcat 
tgaggactt taaattaag accgatcaa ggtttattg 
tttagctgg gaaacagtt tgcgaaatc tgagcgcta 
taacggaat aacgcagtt agttaactg tatcaaatc 
aacaggaat taacgattc agctatttc ggatatgtt 
ggatgaaat gctagcgca cgctgtggg gactttgat 
caaggaaaa catcgaagg gaccaaagt cgaggactt 
gatcaaact tattaacga taaggctac gaagatctc 
tgcatatat tgaagccaa acagttaaa aacggcgta 
tttcctggc cgttaagta caaacgaac ggctgatat 
taggaggat tcagaggga ggctgagtt gttaaatat 
gccaacaat taaggccct gtgccagaa ggtgctgca 
aaactcgcc acacacgca ttccaaaga ctaacctgt 
aaaataaac cgggctgtg atgt
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