Status
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Gene information
General information
TC034004
Former TC numbers

If one gene is splitted or genes are merged, the original TC numbers are listed. One listed former TC number indicates the previous gene has be splitted, serveral former TC number represents a merged gene.

TC005920,TC005916,TC005919,TC005915,TC005917,TC005918
Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007423.3: 5556708..5570711
Sequence information
Transcripts / Proteins (1) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    TC034004
    Gene ontology

    GO terms for Tribolium

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    There are no GO terms for Tribolium at the moment. You can help the community by providing some GO terms for this gene.


    GO terms for the homologous Drosophila genes


    Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term - use "graph views" to browse related terms ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.


    Gene
    {{ goGene }}
    The Tribolium gene the GO term is assigned to.
    GO ID *
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    The ID of the GO term you assign to the gene. Please enter only the ID of the GO term with proceeding 'GO:'. This information is mandatory.
    Evidence
    {{ blurEvidenceResult }}
    The evidence code describes with which method the function or location, expressed by the GO term, was show for this gene. Please refer to this page for a definition of the evidence code and a decision tree.
    Reference *
    {{ blurReferenceResult }}
    The reference where the function or location is described for the gene. Please enter a PubMed ID. This information is mandatory.
    Quotation
    If you paste here the relevant section of the reference it is for us a great help to review your annotation. The quotation may be also be displayed to the users of iBeetle-Base.
    Name
    You may enter your name. The contact information can help us to clarify any questions. If you agree, we may show your name on this page to honor your contribution.
    Email
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    Publish name
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    * : mandatory fields
    For help on how to submit larger datasets or non experimental data please contact us.
    iBeetle screen iB_04038

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 40.0% (includes death as pupa, adult)

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 4 (3 dpi)
    Days post injection


    Fertility
    ovary without detectable defects - Number of animals showing the phenotype: 6
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 70.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 70.0% (includes death as larva, prepupa, pupa, adult)

    larva lethality - Number of animals showing the phenotype: 7 (11 dpi)
    Days post injection


    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC034004 RA
      MATVCCERL LTFCAMSAK QLKSSDNNI LRLDGDKIS 
      LEVRPPSKL STASSKCSL LTKFYSRPV SAVPLLALK 
      DEVDSDSFK TKRPFSAGY LPNSYHNRL ISTREQSID 
      SLESIPDET LSSSDLLKN LLSEPIKSW RNYSSTNST 
      KTEETKTTS PNIVLTPGV QTKPPLPKK PEAKMSSRP 
      EKDPGVNAI HDYLTLKYE SSLEKETEK SKEVEKAPS 
      DDSAINLIS LDDDVKSDL DEQKLNIQN WIEEKDLKW 
      EDDKQIPNL CDIDIDELF KDENDKKFD HFFPTVEDK 
      SPKKKPKAS PKPKVKFIA TPMKSDPDY VDGSKNEVE 
      TWISKKPIS EERKLIFSD FLNNVDELE KSVSLGAVD 
      IPQDIPQHD IDTVPNSPT YEDIASILK VLEAEDKKS 
      QMKMESMKQ VVSEISSKP NDKKAYQSE EEEGKILSS 
      KPTIMITDE SKNKTIDYR SSSNYNELL SFLDEVDRS 
      CSKPLNEVK KIYTRPEPV KLKLDTIPK FEDLITCSN 
      DELARHVID LSLKLKEKS SSITVLQTE LSSLREEIV 
      NTTKKSDQT IKQKLKTQK EEYEGTIKR HQKFIDQLI 
      TDKKSLNQK CEGLVTEMK TMEERFQSN MKAVEHKHN 
      VELQKVKEM AAAAIALKL QQEREEVKE MMRNEVRQE 
      MESLEKELM KVKDSRDNE IQQLYSRVK VSIARKDEI 
      LEELTRDHK ALQEKCAYL ENMLEQQRK DMEKRQQQE 
      LADLRSLHK REIEDLELK AARKMQEQC EALRVQLVE 
      EREKALAHQ REIMRQRYE KLVESEEKG FQEQRRRLL 
      ADHQARVAE CEQREALAL SEKDKAIKQ AQDDFEERL 
      QIVIRRHAN KIKLIKETA TLEMKTWQN NYKKQQTAQ 
      LVEKENIIR EQCRKERDR KIEAVIERL EKEASDNKL 
      QIEQSSENR IRRLKEKYE KEILDLEES ERESKEKYH 
      TVKKKLVES EDVIINLKA TINQLQSQV DSSKAIAQK 
      LQQEREEVK EMMRNEVRQ EMESLEKEL MKVKDSRDN 
      EIQQLYSRV EVSIARKDE ILEELTRDH KAIQEKCAY 
      LENMLEQQR KEKKYEKTT IQHQKFIDQ LITDKKSLN 
      QKCEGLVTE METMEERFQ SNMKAVEHK HNVELQKVK 
      EMPAAGEKL RRERWIDTK TQKIKELTV KSIEPELQS 
      MEKRQQQEL ADLRSLHKR EIEDLELKA ARKMQEQCE 
      ALRLQLVEE REKALAHER EIMRQRYEK LVESEEKGF 
      QEQRRRLLA DHQARVAEC EQREALALS EKDKAIKQA 
      QDDFEERLQ IVIRRHANE IKLIKETAS LEMETWQNN 
      YKKQQTVQL VEKESIIRE QCRKERDRE IEAVIERLE 
      KEASDNKLQ IEQSSENRI RRLKEKYEK EILDLEESE 
      RESKEKYHT LKKKLVESE DVIINLKAT IDQLQNQVD 
      SSKAIALKL QQEREEVKE MMRNEVRQE MESLEKELM 
      KVKDSRNNE IQQLYSRVK VSIARKDEI LEELTRDHK 
      ALQEKCAYL ENMLEQQRK DESTTKKTT KRHQKFIDQ 
      LIADKKFLN QKCEDLVTE MKTMEEHFQ PNMKAVEHK 
      HNVELQKVK EMAAVAEKL RRERWIDTK TQKIKELTV 
      KSIEPELQS MEKRQQQEL ADLRSLHKR EIEDLELKA 
      ARKMQEQCE ALRLQLVEE REKALAHER EIMRQRYEK 
      LVESEEKGF QEQRRRLLA DHQARVAEC EQREALALS 
      EKDKAIKQA QNDFEKKFL EMETWQNNY KKQQTVQLV 
      EKESIIREQ CRKERDREI EAVIERLEK EASDNKLQI 
      EQSSKNRIR RLKEKYEKE ILDLEESER ESKEKYHTV 
      KKKLVESED VVINLKATI DQLQSQVDS SKAIALKLQ 
      QEREEVKEM MRNEVRQEM ESLEKELIK VKDSRANEI 
      QQLYSRVKV SIARKDEIL EELTRDHKA LQEKCAYLE 
      NMLEQQRKD PSNRIVFFS IKKREHDKK NDQTIKQKL 
      KTQKKKYKE TTIRHQKFI DQLITDKKF LNQKCEDLV 
      TEMKTMEEH FQPNMKAVE HKHNVEFQK VKEMAAAGE 
      KLRRERWID TKTQKIKEL TVKSIEPEL QNMEKRQQQ 
      ELADLRSLH KREIEDLEL KAARKMQEQ CEALRLQLV 
      EEREKALAH EREIMRQRY EKLVESEEK GFQEQRRRL 
      LADHQARVA ECEQREALA LSEKDKAIK QAQDDFEER 
      LQIVIRRHA NEIKLIKET ASLEMETWQ NNYKKQQTA 
      QLVEKESII REQCRKERD REIEAVIER LEKEASDNK 
      LQIEQSSEN RIRRLKEKY EKEILDLEE SERESKEKY 
      HTMKKKLVE SEDVIINLK ATIDHLQSQ VDSSKAIAL 
      KLQQEREEV KEMMRNEVR QEMESLEKE LIKVKDSRD 
      NEIQQLYSR VKVSIARKD EILEELTRD HKALQEKCA 
      YLENMLEQQ RKEKKYEKT TIQHQKFID QLIADKKFL 
      NQKCEDLVT ETKTMEEHF QPNMKAVEH KHNVELQKV 
      KEMAAAGEK LRRDRWIDT KTQKIKKLT RQQQELADL 
      RSLHKREIE DLELKAARK MQEQCEALR VQLVKEREK 
      ALAHKREIM RQRYEKLVE SEKKGFQEQ RRRLLADHQ 
      ARVAECEQR EALALSEKD KAIKQAQDD FEERLQIVI 
      RRHANEIKL IKETASLEM ETWQNNYKK QQTAQLVEK 
      ESIIREQCR KERDREIEA IEQSSENQI RRLKEKYEK 
      EILDLEESE RESKEKYPT VKKKLVESE DVIINLKAT 
      IDQLQCQVD SSKAIALKL QQEREEVKE MMRNEVRQE 
      MESLEKELM KVKDSRDNE IQQLYSRVK VSIARKDEI 
      LEELTRDHK ALQEKCAYL ENMLEQQRK EYLIK
    CDS sequence
    • >TC034004 RA
      atggccacc gtttgttgt gagcgcttg ttgacgttt 
      tgcgctatg tcggccaaa caattaaaa tcgagcgat 
      aataatatt ttacgactg gacggcgat aaaataagt 
      ctcgaagtg cgacccccc agtaagtta agcactgca 
      agttccaaa tgttcgttg ttgaccaag ttctattca 
      agacctgtg tccgcagtg ccgctacta gccctaaaa 
      gacgaagtc gattctgat tctttcaag actaaaaga 
      cccttttcc gctggatat cttcctaac agttaccac 
      aatagacta atttcaacc agagagcaa agtattgat 
      agcttagaa agcattcca gatgaaacc ttatcttcg 
      tccgatctt ctcaaaaat ctcctctct gaaccaatc 
      aaatcatgg cgtaattat tcttccacc aactctact 
      aaaaccgaa gaaacaaaa acaacttca ccaaatatt 
      gtcctaact ccaggagtc caaacaaaa ccaccactg 
      cctaaaaaa cctgaagca aaaatgtct tcaagaccc 
      gaaaaagac ccaggtgtt aacgcaatt cacgattat 
      ctaaccctg aaatacgaa tcaagtttg gaaaaagaa 
      acggagaag agcaaagaa gtagaaaaa gctccaagt 
      gatgattct gctatcaat ttgataagt ttagacgac 
      gatgtcaaa tctgattta gatgagcaa aagttgaac 
      atccaaaac tggattgaa gaaaaagat ttgaagtgg 
      gaggacgat aagcaaatt cccaatttg tgcgacatt 
      gacatcgac gagcttttt aaagatgaa aatgacaaa 
      aaatttgat catttcttc ccaaccgtt gaagataaa 
      agtccgaag aagaaacca aaagcttcg ccaaaacct 
      aaagttaag tttatcgcg actccgatg aaatctgac 
      ccggattat gttgatggg tcgaaaaat gaagtcgag 
      acttggatt tccaaaaag ccaatcagt gaagaaagg 
      aaattaatt tttagcgat ttcttgaac aatgtggat 
      gagttggag aaatctgtt tctttgggt gctgttgac 
      attcctcaa gacatccca cagcatgat attgataca 
      gttcctaat agcccaacc tatgaagat atcgcatca 
      attctgaag gtcctagaa gccgaagat aaaaaatct 
      caaatgaag atggagagc atgaaacag gtcgtttca 
      gaaatttct tccaaacct aatgacaaa aaagcgtat 
      caaagtgaa gaagaagaa ggcaaaatt ttgtcgtcc 
      aaacccaca attatgata actgatgaa tcaaaaaat 
      aaaacgatt gattatcgt tcttcttcc aactacaac 
      gaacttctt tcatttctg gacgaagtg gaccgaagt 
      tgttccaag cccttaaac gaggtcaaa aaaatctac 
      actagacca gaaccagtc aaacttaaa ctcgacaca 
      atcccaaaa tttgaagat ttgatcact tgctccaat 
      gacgaattg gcacgtcat gtgattgat ctgagttta 
      aaattgaag gaaaaatcg tcttctatt acagtcctc 
      caaaccgaa ctgtcttcc cttcgagaa gaaatcgtc 
      aacacgacg aaaaaatcc gaccaaaca atcaaacaa 
      aaactgaag acccagaaa gaagaatac gagggaacg 
      atcaaacgg caccaaaaa ttcatcgac cagttgatc 
      accgataaa aaatcgcta aatcagaag tgtgaaggc 
      ttggtcacc gaaatgaag acgatggaa gaacgcttc 
      cagtccaac atgaaagct gttgaacac aaacacaac 
      gttgagctt cagaaagtc aaagaaatg gcagctgct 
      gccatcgca ctgaaactg caacaagaa agagaagaa 
      gtgaaggaa atgatgaga aatgaggtg cggcaagaa 
      atggagagt ttggagaaa gagttgatg aaagtgaaa 
      gattcaaga gataatgag atccaacag ctttattca 
      agagtcaaa gtttcaata gcacgaaaa gacgaaatt 
      ttggaggag ttgacaaga gatcacaaa gccttacag 
      gagaagtgc gcttatttg gagaacatg ttggaacaa 
      cagcgaaag gatatggaa aagcgccaa caacaagaa 
      cttgctgat ttgcgctcg ttacacaag cgggaaatt 
      gaagatttg gaacttaaa gcagctcga aaaatgcaa 
      gaacagtgc gaagcgctt cgagtccaa cttgtggaa 
      gaacgtgaa aaagctttg gcccaccaa cgcgaaatt 
      atgagacaa aggtacgag aaacttgtc gaatcggaa 
      gaaaaaggg ttccaggaa cagagaaga agactactt 
      gctgatcac caagcaaga gttgctgaa tgcgagcaa 
      agggaagct ttagctttg agcgagaaa gataaagcg 
      atcaagcaa gctcaggat gattttgaa gaaaggttg 
      cagattgta atcaggaga cacgctaat aagataaag 
      ttgattaaa gaaacggcc acattagag atgaaaacc 
      tggcagaat aattacaag aagcaacag acggctcag 
      ttggttgag aaagaaaac atcatacga gaacaatgt 
      cggaaggaa cgagacaga aagattgag gcagtgatt 
      gaacgtttg gaaaaagaa gcaagtgat aataagcta 
      cagattgag cagtcaagt gaaaatcgg atcagacgg 
      cttaaggaa aaatacgag aaggaaata ctcgatttg 
      gaggaaagt gaacgcgag tctaaagaa aagtatcac 
      acggtgaag aaaaaactg gttgaaagt gaagacgtg 
      ataattaat ttgaaagca acaatcaat cagttgcaa 
      agccaggtt gactcgtcc aaagccatc gcacagaaa 
      ctgcaacaa gaaagagag gaagtgaag gaaatgatg 
      agaaatgag gttcggcag gaaatggag agtttggag 
      aaagagttg atgaaagtg aaagattcg agagataat 
      gagatccaa cagctttat tcaagagtc gaagtttca 
      atagcacga aaagacgaa attttggag gagttgaca 
      agagatcac aaagccata caagagaag tgcgcttat 
      ttggagaac atgttggaa caacagcga aaggaaaaa 
      aaatacgaa aaaacgacc atacagcac caaaaattt 
      atcgatcaa ttgatcacc gataaaaaa tcgctaaac 
      cagaagtgt gaaggcttg gtcaccgaa atggagacg 
      atggaagaa cgcttccaa tctaacatg aaagctgtt 
      gaacacaaa cacaacgtc gagcttcag aaagtcaaa 
      gaaatgcca gctgctggt gaaaaactg agacgagag 
      cgttggatc gacaccaag acacaaaaa atcaaagaa 
      cttaccgtt aaaagcatc gaaccagaa ttgcaaagt 
      atggaaaaa cgccaacaa caagaactt gctgatttg 
      cgttcccta cacaagcgg gaaattgaa gatttggag 
      cttaaagca gctcgaaaa atgcaagaa cagtgcgaa 
      gcgctgcga ctccaactt gtagaagaa cgtgaaaag 
      gctttggcc cacgaacgc gaaattatg agacaaagg 
      tacgagaaa cttgtcgaa tcggaagaa aaaggtttc 
      caggaacaa agaagaaga ctacttgct gatcaccaa 
      gcaagagtt gctgaatgc gagcaaagg gaagcttta 
      gctttgagc gagaaagat aaagcgata aagcaagct 
      caagatgat tttgaagaa aggttgcaa attgtgatc 
      aggagacac gctaatgaa ataaagttg atcaaagaa 
      acggccagt ttagagatg gaaacctgg cagaataat 
      tacaagaaa caacaaaca gttcagttg gttgagaag 
      gaaagcatc atacgagaa caatgtcgc aaggaacga 
      gacagagag attgaggca gtgattgaa cgtttggaa 
      aaagaagca agtgataat aagctacag attgagcag 
      tcaagtgaa aatcggatc agacggctt aaggaaaaa 
      tacgagaag gaaatactc gatttggag gaaagtgaa 
      cgagagtct aaagaaaag tatcacacg ctgaaaaag 
      aaactggtt gaaagtgaa gacgtgata atcaatttg 
      aaagcaaca atcgatcag ttgcaaaac caggttgac 
      tcgtccaaa gccatcgca ctgaaactg caacaagaa 
      agagaggaa gtgaaggaa atgatgaga aatgaggtg 
      cggcaagaa atggagagt ttggagaaa gagttgatg 
      aaagtgaaa gattcgaga aataatgag atccaacag 
      ctttattca agagtcaaa gtttcaata gcacgaaaa 
      gacgaaatt ttggaggag ttgacaaga gatcacaaa 
      gccttacaa gagaagtgt gcctatttg gagaacatg 
      ttggaacaa cagcgaaag gacgagagc acgacaaaa 
      aaaacgacc aaacggcac caaaaattt atcgatcaa 
      ttgatcgcc gataaaaaa tttctaaac caaaaatgt 
      gaagacttg gtcaccgaa atgaagacg atggaagaa 
      cacttccag cccaacatg aaagctgtg gaacacaaa 
      cacaacgtc gagcttcag aaagtcaaa gaaatggca 
      gctgttgct gaaaaactg agacgagag cgttggatc 
      gacaccaag acacaaaaa atcaaagaa ctgaccgtt 
      aaaagcatc gaaccagaa ttgcaaagt atggaaaaa 
      cgccaacaa caagaactt gctgatttg cgctcgtta 
      cacaagcgg gaaattgaa gatttagaa cttaaagca 
      gctcgaaaa atgcaagaa cagtgcgaa gcgctgcga 
      ctccaactt gtagaagaa cgtgaaaag gccttggcc 
      cacgaacgc gaaattatg agacaaagg tacgagaaa 
      cttgtcgaa tcggaagaa aaagggttc caggaacag 
      agaagaaga ctacttgct gatcaccaa gcaagagtt 
      gctgaatgc gagcaaaga gaagcttta gctttgagc 
      gaaaaagat aaagcgata aagcaagct cagaatgat 
      tttgaaaaa aaattttta gaaatggaa acgtggcaa 
      aataattac aagaagcaa caaacagtt cagttggtt 
      gagaaggag agcatcata cgagaacaa tgtcgcaag 
      gaacgagac agagagatt gaggcagtg attgaacgt 
      ttggaaaaa gaagcaagt gataataag ttacagatt 
      gagcagtca agtaaaaat cggatcaga cgacttaag 
      gaaaaatac gagaaagaa atactcgat ttggaagaa 
      agtgaacgc gagtctaaa gaaaagtat cacacggtg 
      aagaaaaaa ctggttgaa agtgaagac gtggtaatc 
      aatctgaaa gcaacaatc gatcaattg caaagccag 
      gttgactcg tccaaagcc atcgcacta aaactgcaa 
      caagaaaga gaggaagtg aaggaaatg atgagaaat 
      gaggtgcgg caggaaatg gagagttta gagaaagag 
      ttgataaaa gtgaaagat tcaagagct aatgagatc 
      caacagctt tattcaaga gtcaaagtt tcaatagca 
      cgaaaagac gaaattttg gaggagttg acaagagat 
      cacaaagcc ttacaagag aagtgtgcc tatttggag 
      aacatgttg gaacaacag cgaaaggat ccttcaaac 
      cgaattgtc ttcttttca ataaaaaag cgagagcac 
      gacaaaaaa aacgaccaa acaatcaaa caaaaattg 
      aagacccag aaaaaaaaa tacaaagaa acgaccata 
      cggcaccaa aaatttatc gatcaattg atcaccgat 
      aaaaaattt ctaaaccaa aagtgtgaa gacttggtc 
      accgaaatg aaaacgatg gaagaacac ttccagccc 
      aacatgaaa gctgtggaa cacaaacac aacgtcgaa 
      tttcagaaa gttaaagaa atggcagct gctggtgaa 
      aaactgaga cgagagcgt tggatcgac accaagaca 
      caaaaaatc aaagaactg accgttaaa agcatcgaa 
      cccgaatta caaaatatg gaaaaacgc caacaacaa 
      gaacttgct gatttgcgc tcgttacac aagcgggaa 
      attgaagat ttggagctt aaagcagct cgaaaaatg 
      caagaacag tgcgaagcg ctgcgactc caacttgta 
      gaagaacgt gaaaaggct ttggcccac gaacgcgaa 
      attatgagg caaaggtac gagaaactt gtcgaatcg 
      gaagaaaaa gggtttcaa gaacaaaga agaagacta 
      cttgctgat caccaagca agagttgct gaatgcgag 
      caaagggaa gctttagct ttgagcgag aaggataaa 
      gcgataaag caagctcaa gatgatttt gaagaaagg 
      ttgcaaatt gtgatcagg agacacgct aatgagata 
      aagttgatc aaagaaacg gccagttta gagatggag 
      acgtggcaa aataattac aagaagcaa caaacagct 
      cagttggtt gagaaagaa agcatcata cgagaacaa 
      tgtcgcaag gaacgagac agagagatt gaggcggtg 
      attgaacga ctggaaaaa gaagcaagt gataataag 
      ttacagatt gagcagtca agtgaaaat cggatcagg 
      cggcttaag gaaaaatac gagaaagaa atactcgat 
      ttggaagaa agtgaacgc gagtctaaa gaaaagtat 
      cacacgatg aagaaaaaa ctggttgaa agtgaagac 
      gtgataatc aatttgaaa gcaacaatc gatcatttg 
      caaagccaa gttgactcg tccaaagcc atagcactg 
      aaactgcaa caagaaaga gaggaagtg aaggaaatg 
      atgagaaat gaggttcgg caggaaatg gagagtctg 
      gagaaagag ttgataaaa gtgaaagat tcgagagat 
      aatgagatc caacagctt tattcaaga gtcaaagtt 
      tcaatagca cgaaaagac gaaattttg gaggagtta 
      acaagagat cacaaagcc ttacaagag aagtgcgct 
      tatttggag aacatgttg gaacaacag cgaaaggaa 
      aaaaaatac gaaaaaacg accatacag caccaaaaa 
      tttatcgat caattgatc gccgataaa aaatttcta 
      aaccaaaag tgtgaagac ttggtcacc gaaacgaag 
      acgatggaa gaacacttt cagcccaac atgaaagct 
      gtggaacac aaacacaac gtcgagctt cagaaagtc 
      aaagaaatg gcagctgct ggtgaaaaa ctgagacgg 
      gaccgttgg atcgacacc aagacacaa aaaatcaaa 
      aaactgacc cgccaacaa caagaactt gctgatttg 
      cgctcgtta cacaagcgg gaaattgaa gatttggag 
      cttaaagca gctcgaaaa atgcaagaa cagtgcgaa 
      gcgcttcga gtccaactt gtgaaagaa cgtgaaaag 
      gccttggcc cacaaacgc gaaattatg aggcaaaga 
      tacgagaaa cttgtcgaa tcggaaaaa aaaggtttc 
      caggaacag agaagaaga ctacttgct gatcaccaa 
      gcaagagtt gctgaatgc gagcaaagg gaagcttta 
      gctttgagc gagaaagat aaagcgata aagcaagct 
      caagatgat tttgaagaa aggttgcaa attgttatc 
      aggagacac gctaatgag ataaagttg atcaaagaa 
      acggccagt ttagagatg gaaacctgg cagaataat 
      tacaagaag caacaaaca gctcagttg gttgagaaa 
      gaaagcatc atacgagaa caatgtcgc aaggaacgg 
      gacagagag attgaggcg attgagcag tcaagtgaa 
      aatcagatt agacggctt aaggaaaaa tacgagaag 
      gaaatactc gatttagag gaaagtgaa cgcgagtct 
      aaagaaaag tatcccacg gtgaagaag aaacttgtt 
      gaaagtgaa gacgtgata attaatttg aaagcaaca 
      atcgatcag ttgcaatgc caggttgac tcgtccaaa 
      gccatcgca ctgaaactg caacaagaa agagaggaa 
      gtgaaggaa atgatgaga aatgaggtg cggcaagaa 
      atggagagt ttggagaaa gagttgatg aaagtgaaa 
      gattcgaga gataatgag atccaacag ctttattca 
      agagtcaaa gtttcaata gcacgaaaa gacgaaatt 
      ttggaggag ttgacaaga gatcacaaa gccttacaa 
      gagaagtgc gcttatttg gagaacatg ttggaacaa 
      cagcgaaag gagtatttg ataaaatga
    mRNA sequence
    • >TC034004 RA
      cgtttgttt agtctattt atttcggat caaggtggg 
      gtaagttgg acaggtggg ttaggggga catctgttg 
      ggtagcaag ccgtcgcta tggccaccg tttgttgtg 
      agcgcttgt tgacgtttt gcgctatgt cggccaaac 
      aattaaaat cgagcgata ataatattt tacgactgg 
      acggcgata aaataagtc tcgaagtgc gacccccca 
      gtaagttaa gcactgcaa gttccaaat gttcgttgt 
      tgaccaagt tctattcaa gacctgtgt ccgcagtgc 
      cgctactag ccctaaaag acgaagtcg attctgatt 
      ctttcaaga ctaaaagac ccttttccg ctggatatc 
      ttcctaaca gttaccaca atagactaa tttcaacca 
      gagagcaaa gtattgata gcttagaaa gcattccag 
      atgaaacct tatcttcgt ccgatcttc tcaaaaatc 
      tcctctctg aaccaatca aatcatggc gtaattatt 
      cttccacca actctacta aaaccgaag aaacaaaaa 
      caacttcac caaatattg tcctaactc caggagtcc 
      aaacaaaac caccactgc ctaaaaaac ctgaagcaa 
      aaatgtctt caagacccg aaaaagacc caggtgtta 
      acgcaattc acgattatc taaccctga aatacgaat 
      caagtttgg aaaaagaaa cggagaaga gcaaagaag 
      tagaaaaag ctccaagtg atgattctg ctatcaatt 
      tgataagtt tagacgacg atgtcaaat ctgatttag 
      atgagcaaa agttgaaca tccaaaact ggattgaag 
      aaaaagatt tgaagtggg aggacgata agcaaattc 
      ccaatttgt gcgacattg acatcgacg agcttttta 
      aagatgaaa atgacaaaa aatttgatc atttcttcc 
      caaccgttg aagataaaa gtccgaaga agaaaccaa 
      aagcttcgc caaaaccta aagttaagt ttatcgcga 
      ctccgatga aatctgacc cggattatg ttgatgggt 
      cgaaaaatg aagtcgaga cttggattt ccaaaaagc 
      caatcagtg aagaaagga aattaattt ttagcgatt 
      tcttgaaca atgtggatg agttggaga aatctgttt 
      ctttgggtg ctgttgaca ttcctcaag acatcccac 
      agcatgata ttgatacag ttcctaata gcccaacct 
      atgaagata tcgcatcaa ttctgaagg tcctagaag 
      ccgaagata aaaaatctc aaatgaaga tggagagca 
      tgaaacagg tcgtttcag aaatttctt ccaaaccta 
      atgacaaaa aagcgtatc aaagtgaag aagaagaag 
      gcaaaattt tgtcgtcca aacccacaa ttatgataa 
      ctgatgaat caaaaaata aaacgattg attatcgtt 
      cttcttcca actacaacg aacttcttt catttctgg 
      acgaagtgg accgaagtt gttccaagc ccttaaacg 
      aggtcaaaa aaatctaca ctagaccag aaccagtca 
      aacttaaac tcgacacaa tcccaaaat ttgaagatt 
      tgatcactt gctccaatg acgaattgg cacgtcatg 
      tgattgatc tgagtttaa aattgaagg aaaaatcgt 
      cttctatta cagtcctcc aaaccgaac tgtcttccc 
      ttcgagaag aaatcgtca acacgacga aaaaatccg 
      accaaacaa tcaaacaaa aactgaaga cccagaaag 
      aagaatacg agggaacga tcaaacggc accaaaaat 
      tcatcgacc agttgatca ccgataaaa aatcgctaa 
      atcagaagt gtgaaggct tggtcaccg aaatgaaga 
      cgatggaag aacgcttcc agtccaaca tgaaagctg 
      ttgaacaca aacacaacg ttgagcttc agaaagtca 
      aagaaatgg cagctgctg ccatcgcac tgaaactgc 
      aacaagaaa gagaagaag tgaaggaaa tgatgagaa 
      atgaggtgc ggcaagaaa tggagagtt tggagaaag 
      agttgatga aagtgaaag attcaagag ataatgaga 
      tccaacagc tttattcaa gagtcaaag tttcaatag 
      cacgaaaag acgaaattt tggaggagt tgacaagag 
      atcacaaag ccttacagg agaagtgcg cttatttgg 
      agaacatgt tggaacaac agcgaaagg atatggaaa 
      agcgccaac aacaagaac ttgctgatt tgcgctcgt 
      tacacaagc gggaaattg aagatttgg aacttaaag 
      cagctcgaa aaatgcaag aacagtgcg aagcgcttc 
      gagtccaac ttgtggaag aacgtgaaa aagctttgg 
      cccaccaac gcgaaatta tgagacaaa ggtacgaga 
      aacttgtcg aatcggaag aaaaagggt tccaggaac 
      agagaagaa gactacttg ctgatcacc aagcaagag 
      ttgctgaat gcgagcaaa gggaagctt tagctttga 
      gcgagaaag ataaagcga tcaagcaag ctcaggatg 
      attttgaag aaaggttgc agattgtaa tcaggagac 
      acgctaata agataaagt tgattaaag aaacggcca 
      cattagaga tgaaaacct ggcagaata attacaaga 
      agcaacaga cggctcagt tggttgaga aagaaaaca 
      tcatacgag aacaatgtc ggaaggaac gagacagaa 
      agattgagg cagtgattg aacgtttgg aaaaagaag 
      caagtgata ataagctac agattgagc agtcaagtg 
      aaaatcgga tcagacggc ttaaggaaa aatacgaga 
      aggaaatac tcgatttgg aggaaagtg aacgcgagt 
      ctaaagaaa agtatcaca cggtgaaga aaaaactgg 
      ttgaaagtg aagacgtga taattaatt tgaaagcaa 
      caatcaatc agttgcaaa gccaggttg actcgtcca 
      aagccatcg cacagaaac tgcaacaag aaagagagg 
      aagtgaagg aaatgatga gaaatgagg ttcggcagg 
      aaatggaga gtttggaga aagagttga tgaaagtga 
      aagattcga gagataatg agatccaac agctttatt 
      caagagtcg aagtttcaa tagcacgaa aagacgaaa 
      ttttggagg agttgacaa gagatcaca aagccatac 
      aagagaagt gcgcttatt tggagaaca tgttggaac 
      aacagcgaa aggaaaaaa aatacgaaa aaacgacca 
      tacagcacc aaaaattta tcgatcaat tgatcaccg 
      ataaaaaat cgctaaacc agaagtgtg aaggcttgg 
      tcaccgaaa tggagacga tggaagaac gcttccaat 
      ctaacatga aagctgttg aacacaaac acaacgtcg 
      agcttcaga aagtcaaag aaatgccag ctgctggtg 
      aaaaactga gacgagagc gttggatcg acaccaaga 
      cacaaaaaa tcaaagaac ttaccgtta aaagcatcg 
      aaccagaat tgcaaagta tggaaaaac gccaacaac 
      aagaacttg ctgatttgc gttccctac acaagcggg 
      aaattgaag atttggagc ttaaagcag ctcgaaaaa 
      tgcaagaac agtgcgaag cgctgcgac tccaacttg 
      tagaagaac gtgaaaagg ctttggccc acgaacgcg 
      aaattatga gacaaaggt acgagaaac ttgtcgaat 
      cggaagaaa aaggtttcc aggaacaaa gaagaagac 
      tacttgctg atcaccaag caagagttg ctgaatgcg 
      agcaaaggg aagctttag ctttgagcg agaaagata 
      aagcgataa agcaagctc aagatgatt ttgaagaaa 
      ggttgcaaa ttgtgatca ggagacacg ctaatgaaa 
      taaagttga tcaaagaaa cggccagtt tagagatgg 
      aaacctggc agaataatt acaagaaac aacaaacag 
      ttcagttgg ttgagaagg aaagcatca tacgagaac 
      aatgtcgca aggaacgag acagagaga ttgaggcag 
      tgattgaac gtttggaaa aagaagcaa gtgataata 
      agctacaga ttgagcagt caagtgaaa atcggatca 
      gacggctta aggaaaaat acgagaagg aaatactcg 
      atttggagg aaagtgaac gagagtcta aagaaaagt 
      atcacacgc tgaaaaaga aactggttg aaagtgaag 
      acgtgataa tcaatttga aagcaacaa tcgatcagt 
      tgcaaaacc aggttgact cgtccaaag ccatcgcac 
      tgaaactgc aacaagaaa gagaggaag tgaaggaaa 
      tgatgagaa atgaggtgc ggcaagaaa tggagagtt 
      tggagaaag agttgatga aagtgaaag attcgagaa 
      ataatgaga tccaacagc tttattcaa gagtcaaag 
      tttcaatag cacgaaaag acgaaattt tggaggagt 
      tgacaagag atcacaaag ccttacaag agaagtgtg 
      cctatttgg agaacatgt tggaacaac agcgaaagg 
      acgagagca cgacaaaaa aaacgacca aacggcacc 
      aaaaattta tcgatcaat tgatcgccg ataaaaaat 
      ttctaaacc aaaaatgtg aagacttgg tcaccgaaa 
      tgaagacga tggaagaac acttccagc ccaacatga 
      aagctgtgg aacacaaac acaacgtcg agcttcaga 
      aagtcaaag aaatggcag ctgttgctg aaaaactga 
      gacgagagc gttggatcg acaccaaga cacaaaaaa 
      tcaaagaac tgaccgtta aaagcatcg aaccagaat 
      tgcaaagta tggaaaaac gccaacaac aagaacttg 
      ctgatttgc gctcgttac acaagcggg aaattgaag 
      atttagaac ttaaagcag ctcgaaaaa tgcaagaac 
      agtgcgaag cgctgcgac tccaacttg tagaagaac 
      gtgaaaagg ccttggccc acgaacgcg aaattatga 
      gacaaaggt acgagaaac ttgtcgaat cggaagaaa 
      aagggttcc aggaacaga gaagaagac tacttgctg 
      atcaccaag caagagttg ctgaatgcg agcaaagag 
      aagctttag ctttgagcg aaaaagata aagcgataa 
      agcaagctc agaatgatt ttgaaaaaa aatttttag 
      aaatggaaa cgtggcaaa ataattaca agaagcaac 
      aaacagttc agttggttg agaaggaga gcatcatac 
      gagaacaat gtcgcaagg aacgagaca gagagattg 
      aggcagtga ttgaacgtt tggaaaaag aagcaagtg 
      ataataagt tacagattg agcagtcaa gtaaaaatc 
      ggatcagac gacttaagg aaaaatacg agaaagaaa 
      tactcgatt tggaagaaa gtgaacgcg agtctaaag 
      aaaagtatc acacggtga agaaaaaac tggttgaaa 
      gtgaagacg tggtaatca atctgaaag caacaatcg 
      atcaattgc aaagccagg ttgactcgt ccaaagcca 
      tcgcactaa aactgcaac aagaaagag aggaagtga 
      aggaaatga tgagaaatg aggtgcggc aggaaatgg 
      agagtttag agaaagagt tgataaaag tgaaagatt 
      caagagcta atgagatcc aacagcttt attcaagag 
      tcaaagttt caatagcac gaaaagacg aaattttgg 
      aggagttga caagagatc acaaagcct tacaagaga 
      agtgtgcct atttggaga acatgttgg aacaacagc 
      gaaaggatc cttcaaacc gaattgtct tcttttcaa 
      taaaaaagc gagagcacg acaaaaaaa acgaccaaa 
      caatcaaac aaaaattga agacccaga aaaaaaaat 
      acaaagaaa cgaccatac ggcaccaaa aatttatcg 
      atcaattga tcaccgata aaaaatttc taaaccaaa 
      agtgtgaag acttggtca ccgaaatga aaacgatgg 
      aagaacact tccagccca acatgaaag ctgtggaac 
      acaaacaca acgtcgaat ttcagaaag ttaaagaaa 
      tggcagctg ctggtgaaa aactgagac gagagcgtt 
      ggatcgaca ccaagacac aaaaaatca aagaactga 
      ccgttaaaa gcatcgaac ccgaattac aaaatatgg 
      aaaaacgcc aacaacaag aacttgctg atttgcgct 
      cgttacaca agcgggaaa ttgaagatt tggagctta 
      aagcagctc gaaaaatgc aagaacagt gcgaagcgc 
      tgcgactcc aacttgtag aagaacgtg aaaaggctt 
      tggcccacg aacgcgaaa ttatgaggc aaaggtacg 
      agaaacttg tcgaatcgg aagaaaaag ggtttcaag 
      aacaaagaa gaagactac ttgctgatc accaagcaa 
      gagttgctg aatgcgagc aaagggaag ctttagctt 
      tgagcgaga aggataaag cgataaagc aagctcaag 
      atgattttg aagaaaggt tgcaaattg tgatcagga 
      gacacgcta atgagataa agttgatca aagaaacgg 
      ccagtttag agatggaga cgtggcaaa ataattaca 
      agaagcaac aaacagctc agttggttg agaaagaaa 
      gcatcatac gagaacaat gtcgcaagg aacgagaca 
      gagagattg aggcggtga ttgaacgac tggaaaaag 
      aagcaagtg ataataagt tacagattg agcagtcaa 
      gtgaaaatc ggatcaggc ggcttaagg aaaaatacg 
      agaaagaaa tactcgatt tggaagaaa gtgaacgcg 
      agtctaaag aaaagtatc acacgatga agaaaaaac 
      tggttgaaa gtgaagacg tgataatca atttgaaag 
      caacaatcg atcatttgc aaagccaag ttgactcgt 
      ccaaagcca tagcactga aactgcaac aagaaagag 
      aggaagtga aggaaatga tgagaaatg aggttcggc 
      aggaaatgg agagtctgg agaaagagt tgataaaag 
      tgaaagatt cgagagata atgagatcc aacagcttt 
      attcaagag tcaaagttt caatagcac gaaaagacg 
      aaattttgg aggagttaa caagagatc acaaagcct 
      tacaagaga agtgcgctt atttggaga acatgttgg 
      aacaacagc gaaaggaaa aaaaatacg aaaaaacga 
      ccatacagc accaaaaat ttatcgatc aattgatcg 
      ccgataaaa aatttctaa accaaaagt gtgaagact 
      tggtcaccg aaacgaaga cgatggaag aacactttc 
      agcccaaca tgaaagctg tggaacaca aacacaacg 
      tcgagcttc agaaagtca aagaaatgg cagctgctg 
      gtgaaaaac tgagacggg accgttgga tcgacacca 
      agacacaaa aaatcaaaa aactgaccc gccaacaac 
      aagaacttg ctgatttgc gctcgttac acaagcggg 
      aaattgaag atttggagc ttaaagcag ctcgaaaaa 
      tgcaagaac agtgcgaag cgcttcgag tccaacttg 
      tgaaagaac gtgaaaagg ccttggccc acaaacgcg 
      aaattatga ggcaaagat acgagaaac ttgtcgaat 
      cggaaaaaa aaggtttcc aggaacaga gaagaagac 
      tacttgctg atcaccaag caagagttg ctgaatgcg 
      agcaaaggg aagctttag ctttgagcg agaaagata 
      aagcgataa agcaagctc aagatgatt ttgaagaaa 
      ggttgcaaa ttgttatca ggagacacg ctaatgaga 
      taaagttga tcaaagaaa cggccagtt tagagatgg 
      aaacctggc agaataatt acaagaagc aacaaacag 
      ctcagttgg ttgagaaag aaagcatca tacgagaac 
      aatgtcgca aggaacggg acagagaga ttgaggcga 
      ttgagcagt caagtgaaa atcagatta gacggctta 
      aggaaaaat acgagaagg aaatactcg atttagagg 
      aaagtgaac gcgagtcta aagaaaagt atcccacgg 
      tgaagaaga aacttgttg aaagtgaag acgtgataa 
      ttaatttga aagcaacaa tcgatcagt tgcaatgcc 
      aggttgact cgtccaaag ccatcgcac tgaaactgc 
      aacaagaaa gagaggaag tgaaggaaa tgatgagaa 
      atgaggtgc ggcaagaaa tggagagtt tggagaaag 
      agttgatga aagtgaaag attcgagag ataatgaga 
      tccaacagc tttattcaa gagtcaaag tttcaatag 
      cacgaaaag acgaaattt tggaggagt tgacaagag 
      atcacaaag ccttacaag agaagtgcg cttatttgg 
      agaacatgt tggaacaac agcgaaagg agtatttga 
      taaaatgag ttttgtatc atacaactg acgattttc 
      caattatat tattcattt ttcgataaa tgtgttttc 
      ccacttctc attaacaga gccatgtat caatgtaat 
      tacaatata attatggca acaga
    The data is licensed under a Creative Commons Attribution 3.0 Unported License. (CC-BY) CC-BY