Status
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Gene information
General information
TC003876 Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007418.3: 25573139..25625161
Sequence information
Transcripts / Proteins (1) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    TC003876
    Gene ontology

    GO terms for Tribolium

    • {{ goTerm.term }}
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      Status: {{ goTerm.status }}
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      Quotation: {{ goTerm.quotation }}
      Submitter: {{ goTerm.name }}

    There are no GO terms for Tribolium at the moment. You can help the community by providing some GO terms for this gene.


    GO terms for the homologous Drosophila genes


    Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term - use "graph views" to browse related terms ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.


    Gene
    {{ goGene }}
    The Tribolium gene the GO term is assigned to.
    GO ID *
    {{ blurIdResult }}
    The ID of the GO term you assign to the gene. Please enter only the ID of the GO term with proceeding 'GO:'. This information is mandatory.
    Evidence
    {{ blurEvidenceResult }}
    The evidence code describes with which method the function or location, expressed by the GO term, was show for this gene. Please refer to this page for a definition of the evidence code and a decision tree.
    Reference *
    {{ blurReferenceResult }}
    The reference where the function or location is described for the gene. Please enter a PubMed ID. This information is mandatory.
    Quotation
    If you paste here the relevant section of the reference it is for us a great help to review your annotation. The quotation may be also be displayed to the users of iBeetle-Base.
    Name
    You may enter your name. The contact information can help us to clarify any questions. If you agree, we may show your name on this page to honor your contribution.
    Email
    We will use your email address only for possible questions regarding this annotation. We will never show your address or give it away.
    Publish name
    If you have entered your name and agree by marking the checkbox. we might show your name on this page to honor your contribution.
      {{ unavailableText }}

    * : mandatory fields
    For help on how to submit larger datasets or non experimental data please contact us.
    iBeetle screen iB_07076

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 10.0% (includes death as pupa, adult)

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 1 (3 dpi)
    Days post injection


    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: < 50
    head capsule size decreased - Penetrance (percentage of animals/eggs on slide): 30% - 50%

    head appendages potentially slightlysize decreased - Penetrance (percentage of animals/eggs on slide): 30% - 50%

    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): 30% - 50%
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: % (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: % (includes death as larva, prepupa, pupa, adult)

    iBeetle screen iB_03644

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 20.0% (includes death as pupa, adult)

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 2 (3 dpi)
    Days post injection


    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: < 20
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: % (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: % (includes death as larva, prepupa, pupa, adult)

    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC003876 RA
      MSTDICRWL FLLFFLTTW TKYSNSKEI RVVCYYTNW 
      SVYRPGTAK FSPQNINPY LCTHLIYAF GGFTKENTL 
      KPFDKYQDI EKGGYAKFT GLKTYNKNL KTMLAIGGW 
      NEGSSRFSP MVANPERRK ELIKNAIKF LRQNHFDGL 
      DLDWEYPSF RDGGKSRDK DNYAQLVQE LREEFDRES 
      EKTGRPRLL LTMAVPAGI EYINKGYDV PKLTKYLDW 
      MNILSYDYH SAFEPAVNH HAPLYPLEE PSEYNYDTE 
      LNIDYTIQH YLKKGADPS KLVLGIPTY GRSYTLFNP 
      DANEIGAPA DGPGDMGEA TRENGYLAY YEVCEYIKT 
      QNWEVVQPN PDAMGPYAF KDNQWVGYD DDKIARKKA 
      EYVAEKGLG GIMFWSIDN DDFRGNCHG KPYPIIEAA 
      KEALISAYG LTDENLVSP PTKPIKTKT RNRTQSSSK 
      STDENSEKK KSTSSIVSR RRNRIKTKS EELSNSQSK 
      SHRKESRRT TEGPVYSSL ELVTPSYTT PAPPSTPDL 
      GGGFKCEDE GFYPHPKDC KKYYWCLSG PGELGIVAH 
      LFTCPAGLY FNKAADSCD YTRNVLCNK KLSKATTTT 
      TTTTTTEAS TLKTSTARV PPKITAATS RTTVFRTST 
      TTEAYDDEY EYEDDVEEN KNSEEDPKV IKELLDLIK 
      KAGGIEELE KQLKIHEDG SASVSNSDT TTPSSISKS 
      LVERVLGKG AKVGGKKNS YSFLTRNSR GPQNEGLNT 
      HEDKETTQD KGRPKYTTI TRQRSTNNK NEDEEEESS 
      DEASKSTKK QPEYVNIRR ARVSTTTEE PEENSKSQL 
      NRNKILGEE DETEDEQPS RKKTSGPQY VNIRRQRPS 
      TTEETSTSK YTVIRRGTT TEPAEPEED ETTKSNVVS 
      TSTEKIDLK SRYSILRRG STTEATTTE SGSISSTSS 
      PKRRGTTLP SVPERKRTR GTLAPGTTP SSEDTTTTR 
      YKSIKRGST SEAPTTDKT LPEDSTLKY STFTRTPAS 
      TQAAPAATE PETAVTVNV QLLTTPESL TVKTTSLSS 
      TKQSEQSNI ESIGERVYQ TQTPLLLEP RPFSKTSTR 
      SPTPVVTES STRITKVSD SNYNLRLKP KLSQTQTEI 
      ISTTTLTTE KPTPFRTRA PSRFKLTTA SYDQQATKQ 
      ANRARKRFS TTTELYSDN YEEFDLSRT YRPSEIADL 
      SSLTAVDFV ALKELTRNS NSLRQRRPR PESTTPRTS 
      SFKSRRLIS NKNEQNVED QVNSSSDKT HRIRGFTRS 
      PPVVSTTTE GTTRHSLRN RKVVRRLRP TSSSKLLSQ 
      NSDNKENVV PFKKRLVRP NTETENLIE NSSLNSLFN 
      RRLTRPTEA PNEEQSDDV SAEEGENIK LSESNIREN 
      SNVNNNNNN ILSPDDGQK VRRKVLKRI KPKVDDEKI 
      VTEPNIVIR TRKIVRKLT PTESTITST TETTVPGRK 
      RKIIRRLRP TTELKENST QKTLYIRGR PFLAHFNNE 
      ESGVDASTI KPDSSKYST PNRGTTEES EVTEQFIAN 
      SENTDSYKG TTEEAEAKK QLISNSENS SQRTTDSYK 
      GTTEEADSS TERTIDRSK YSTLNRGTI DSTREESFD 
      KEIITTDRG PSRFRSTTE GTIDRTKYS TLNKGTTEE 
      PEVREHFIS NSDTSTERT IDRSKYSTL NRGTTESTK 
      EEKIDEETI TTNRGPSRF RNSNTSTEG TIDRSKYST 
      LNRGTTEEA EVKEQHISS SDASTEGTI DRSKYSTLN 
      RGTTEEAEV KEQHISNSD ASTEGTIDR SKYSTLNRG 
      TTESAKEEK IDEEIISTN RGPSRFRIY RPTVFHDDD 
      EEEEEDDSL KTRIVEPLF TEEITESNK LSNNATNKT 
      DDLNKEEAD EENSTIETN EENSTEEHK DEEDNEDIP 
      VTTVKPYIN PILNRQKNR PAFQRPKLT TQKPLSSST 
      TSRNRYKTF GRSTTAPSK ETNEEITQE KFVPKNLDR 
      NRKVSTSTT TTEVAPEIE QTTDSVQIN DTESDKTTL 
      ESIEVTTLK ETEEVVNAT TESRTILVE TTTLRTTET 
      TPSHLPRST SRTRPKFNV PKRLTTPES RFSPKLRTQ 
      STTPKAPTS LLKDKFTRK YTTTERNDF VEEEDIPEE 
      DEVENQSST QRTTRPKAR PSNRPDFRK STEAPKPTE 
      DLKGIDTDA VKNRNKNLF SKKRKMNTP FAGHPLNQS 
      ILTTTPTIS ESVTKPSTE PFETTEYLT TLHHIFAET 
      ERVTENSLP TTTSSKIEK LIEVNRIVE VHEMNNTEE 
      RDNKVVDKV GVINRVTVV KVVDGNFNP EDNEITKSP 
      KLDDFEIAT VREIPNRED RRYEQVAES AEIIDGRSN 
      INIITPRPY YSTEASTIS LEGLFQTDT PQKLSDKFN 
      LNQLKQGTN DEELLETGN SRYVNVRVL KEDDYITMK 
      AEVVEVTPK ISKDIKIVP IQVEMSRKL IAPSDFVTK 
      VEQGVPKVT LQILKPQN
    CDS sequence
    • >TC003876 RA
      atgtcgacg gatatctgt cgatggttg ttcctcctg 
      ttttttcta acaacatgg accaaatat tcaaattca 
      aaggagatc cgcgtggtc tgttactac acgaactgg 
      tcagtttac aggcccgga acagcaaaa tttagccca 
      caaaatatc aacccctat ttatgcaca catctcatt 
      tatgcattc gggggtttt accaaagaa aatacgctc 
      aagccgttc gataaatac caagatatc gaaaaaggt 
      ggttatgca aaattcacc ggattgaag acatacaac 
      aagaactta aagacaatg ctagccatt ggtggctgg 
      aacgaaggt tcttccaga ttttctcca atggtggca 
      aaccctgaa aggcgaaaa gaactgatc aaaaacgcc 
      atcaagttt ttgagacaa aatcacttc gatggtctt 
      gatctggac tgggaatat ccgagcttc cgagatggg 
      ggaaaatca agagataaa gacaactac gcccaatta 
      gtccaggaa cttcgggaa gaatttgac cgagaatcg 
      gaaaaaaca ggaagaccg agattactt ctgacaatg 
      gcagttcct gcaggaatt gagtacatt aacaaagga 
      tacgatgta cccaaactc accaagtac ctcgattgg 
      atgaatatt ttgagttac gattaccac tctgccttc 
      gaaccggct gttaaccac catgcccca ctttaccca 
      cttgaagaa ccctctgaa tataattac gatacggaa 
      cttaacatt gactacacg attcaacac tacttgaaa 
      aaaggagcc gatcctagc aaacttgtc ctaggaata 
      ccaacttac ggccgctct tacacttta tttaaccca 
      gatgccaac gaaattgga gcaccagct gatgggcct 
      ggagatatg ggtgaagca acaagagaa aatggttat 
      ttggcctac tacgaggtc tgcgagtac attaaaacc 
      cagaactgg gaagtagtc caaccaaat ccagacgcc 
      atgggtccg tacgccttc aaggacaac caatgggtg 
      ggatatgac gatgataaa attgcaagg aaaaaagcc 
      gaatatgtg gcagagaaa ggccttggt gggataatg 
      ttttggtcg attgataac gacgatttt aggggaaat 
      tgccacggg aaaccttac cctattatc gaagcagca 
      aaagaagcg ttaatttca gcctatgga ttgacagac 
      gagaatttg gtttcaccc ccaaccaag ccaatcaaa 
      acaaaaacg agaaacagg acccaatct tcatccaaa 
      tcaactgac gaaaatagc gaaaaaaag aaaagtaca 
      agttctatt gtgtccaga agacgcaac agaattaaa 
      accaaatcg gaagaactt tcaaacagc caatcaaaa 
      tcccacagg aaggaaagc cgaagaaca acagaaggg 
      ccagtttac agtagttta gaattagtt acacccagt 
      tatacaaca cctgcccca ccctcaacg ccagatctg 
      ggcggaggt ttcaaatgt gaagatgaa ggtttctac 
      ccacaccct aaagactgt aaaaagtat tactggtgt 
      ctcagcggg cctggagag cttggaatc gttgcccat 
      ttgtttacc tgtccagca ggtctgtat ttcaacaaa 
      gcggctgat tcttgtgat tacactcgc aatgttctg 
      tgcaataaa aaactatca aaggccaca acgaccaca 
      actacaaca accacaaca gaggccagt actttgaaa 
      acatcaacc gcaagagta ccacctaaa attacagcg 
      gccacaagt cgaactaca gtttttcgg acttcgacc 
      acaactgaa gcttacgat gacgagtat gaatatgaa 
      gacgatgtt gaagagaat aaaaattcg gaagaagat 
      cctaaggtt attaaggaa ttgctcgat cttatcaag 
      aaagctgga ggaattgaa gaacttgaa aaacagttg 
      aaaattcat gaagatggc agtgcttcc gtttcaaac 
      tctgacaca actactcct tcgtctatt agcaagtca 
      ctggtggaa agggtttta ggcaaagga gccaaagtt 
      ggtggaaaa aagaattct tatagtttc ctcacccgc 
      aacagtcga ggccctcaa aacgagggt ttgaacaca 
      catgaagat aaagaaacg acacaagat aaaggaaga 
      ccaaaatac acaacaatc acaagacaa agatcaaca 
      aataacaaa aatgaagac gaagaagag gaatcctca 
      gacgaagca tccaaatct acgaaaaaa caaccagaa 
      tatgtcaac attaggcga gcccgagtt agtactact 
      acagaagaa ccggaagaa aattcaaag agtcaacta 
      aaccgaaat aaaattttg ggagaagag gacgaaaca 
      gaagatgaa caaccaagt cgtaagaaa acatcaggg 
      ccacaatat gttaacata cggaggcaa aggccatca 
      acaactgaa gaaacttca acttcaaaa tatactgtt 
      ataagaaga gggacaaca actgaaccc gctgaacca 
      gaagaagac gaaaccact aaaagcaat gttgtttca 
      acatccacc gaaaaaatt gatttaaaa tcaaggtat 
      agcattctt aggcgagga tcaacgact gaagcaact 
      acaactgag agtggttca atctcttca acctcttca 
      ccaaagaga agaggaaca acactgcca agtgttcca 
      gaacggaaa agaacgaga ggtacttta gctccaggg 
      actacgcca tcgtcagaa gatacgaca acaacaaga 
      tataagagt attaagcga ggttcaaca agcgaagca 
      cccacaaca gacaagaca ttacccgaa gattcaact 
      ctaaagtac tccaccttc acccgcaca cctgcatcc 
      acccaggcc gccccagca gccaccgaa cccgaaacc 
      gccgtaact gttaacgtt caattacta acaaccccc 
      gaaagttta actgtaaaa acaactagt cttagttcc 
      acaaaacag tcggaacaa tcaaacatt gaaagtatc 
      ggtgaaaga gtctatcag acacagact cccttactt 
      ttagaacct cgcccattt tcaaaaact agtactcga 
      agtccaaca ccggtagta accgaatca tccacacga 
      atcacaaag gtgagtgac tcaaattat aacctccga 
      ctaaagccg aaactgtcg caaacgcaa accgaaatt 
      attagcacc actactctc accaccgaa aaaccaaca 
      ccgtttaga actagagca ccgtctaga tttaagtta 
      accacagcg agttacgac caacaagcc acaaagcaa 
      gcaaatcgg gccaggaaa cgcttttcc acaacgacc 
      gaattgtat tcggacaac tacgaggag tttgatttg 
      agtcgaacg tacagaccg tcagaaatt gcagatttg 
      tcgtcactg acagctgtt gatttcgta gctttgaag 
      gagctcacc agaaacagc aattctcta agacagaga 
      aggcctaga cctgaaagt accactccc agaacgtca 
      tcttttaaa agcagacga ttgatttcg aacaaaaat 
      gagcaaaat gtggaagat caagtaaat tcaagctct 
      gataaaaca cacagaatt cgaggtttc acaagatca 
      cctcctgtt gtcagtaca acaactgaa ggaacaaca 
      agacatagt ttaaggaac aggaaagtc gtccgtcgt 
      ttaagaccc acgtcaagt tccaaacta ttatcgcaa 
      aattcagac aacaaggaa aacgttgtc cctttcaaa 
      aaacgtttg gttcgacca aacacagaa acagaaaac 
      ttgatcgaa aactcctcg ttaaattca ctcttcaac 
      aggcgttta actcgcccc actgaagcc ccaaacgag 
      gaacaaagc gacgatgtc agcgctgaa gaaggggaa 
      aacattaaa ctatccgaa tcaaatatc agagaaaac 
      agcaatgtt aataacaac aacaacaac attctctcg 
      cctgacgat ggccagaaa gttagacgc aaagtttta 
      aaacgcatc aaacccaaa gtagacgac gagaaaatt 
      gtcacagaa ccgaacatt gtcatcaga acacgaaaa 
      attgtcaga aagttaaca ccaaccgaa tctacaatt 
      acttcgacc actgagaca acagtacca ggccgtaaa 
      cgaaaaatt attcggcgt ttgagacct acaaccgag 
      ttgaaggaa aatagtacg cagaaaacg ttgtacatt 
      aggggaaga ccctttttg gcacatttc aacaacgaa 
      gaatctgga gttgatgca agtaccatt aaaccagac 
      tcttctaaa tatagtact cctaacaga ggaacgact 
      gaagaatca gaagttacg gaacaattt atagcaaat 
      tctgaaaat actgatagt tacaaagga acaactgaa 
      gaagcagaa gctaagaaa caattgata tcaaattct 
      gaaaactct tctcaaaga actactgat agttacaaa 
      ggaacaact gaagaagca gatagttct actgaacga 
      actattgat agatctaaa tacagtact cttaacaga 
      ggaacaata gactctaca agagaggaa agttttgat 
      aaagagata ataactaca gacagaggt ccatcaagg 
      tttagaagt actactgaa ggaactatt gatagaact 
      aaatacagt actcttaac aaaggaaca actgaagaa 
      ccagaagtt cgggaacac tttatatca aattctgac 
      acttctact gaaagaact attgataga tctaaatac 
      agtactctt aacagagga acaacagag tctacaaaa 
      gaggaaaaa attgatgaa gaaactata actacaaac 
      aggggacca tcaaggttt agaaattct aacacttct 
      actgaagga actattgat agatctaaa tatagtact 
      cttaacaga ggaacaact gaagaagca gaagttaag 
      gaacaacat atatcaagt tctgatgct tctactgaa 
      ggaactatt gatagatct aaatacagt actcttaac 
      agaggaaca actgaagaa gcagaagtt aaggaacaa 
      catatatca aattctgat gcttctact gaaggaacc 
      attgataga tctaaatac agtactctt aacagagga 
      acaacagag tcggcaaaa gaggaaaaa attgatgaa 
      gagataata agtacaaac agaggtcca tcaaggttt 
      agaatttat cgaccaact gttttccat gatgatgac 
      gaagaagag gaagaagac gattcgttg aaaactcga 
      attgtggaa cctttattc accgaagaa ataacagaa 
      agtaacaag ttatctaat aacgcaact aacaaaact 
      gacgatttg aataaagaa gaagcagat gaggaaaat 
      agtacaata gaaactaat gaggaaaat agtaccgaa 
      gagcataag gatgaggaa gataatgaa gatatacct 
      gtgacaact gtcaaacct tacatcaac ccaattctc 
      aacagacag aaaaataga cccgccttt caaagacct 
      aaactaaca acacaaaag cctttgtcg tctagtaca 
      accagtaga aatagatac aagaccttc ggtagatcg 
      acaacagct cctagtaaa gaaacgaat gaggaaata 
      acacaagaa aaattcgta ccgaaaaat ttggatcga 
      aaccgaaaa gtctcaact tctaccaca accactgaa 
      gttgctcca gaaattgaa cagacaaca gacagcgtt 
      caaataaat gatacggaa agtgataag acaacttta 
      gagagcatt gaagttacc acattgaaa gaaacagag 
      gaagtggtt aatgctacg actgaaagt cggacaatt 
      ttggttgaa acaactacg ttaagaact actgaaact 
      actccaagt catcttccc agaagtact tccagaacc 
      agaccaaaa tttaacgtc ccaaaaaga ctaacaaca 
      cccgaaagt agatttagc ccaaaactt cgaactcaa 
      agtacgacc cccaaagca ccaacttct ctactaaag 
      gataaattt actcgcaaa tacactacg actgaacga 
      aatgatttc gttgaggaa gaagacatt ccagaggaa 
      gacgaagtc gaaaatcaa tcttccaca caaagaaca 
      acacgacct aaagctaga ccaagtaac agaccagac 
      ttcaggaag tcaacagaa gctccaaaa ccaaccgaa 
      gacttgaaa ggaattgac actgacgcc gtcaaaaac 
      cggaacaaa aatctcttc tcgaaaaaa cgcaaaatg 
      aacacacct ttcgcaggc catccccta aaccagtca 
      attttaacc acaactccg accatttcc gaatcggtc 
      acaaaacca tcaacggaa ccgttcgaa accactgaa 
      tacctcaca actttgcac cacattttt gccgaaact 
      gaacgtgtc actgaaaat agtttgcca acaaccacg 
      agttccaaa attgagaaa ttgatcgaa gtgaaccga 
      attgtggaa gtgcacgaa atgaacaac acggaagag 
      agggacaat aaagtggtt gataaagtt ggtgttatc 
      aatcgggtg acggtggtt aaggttgtt gacggtaat 
      tttaacccg gaagataac gaaattacg aaatcgcca 
      aagttggat gattttgaa attgcaact gttcgggaa 
      atacctaat cgggaagat cgcagatac gaacaagtt 
      gccgaaagt gctgaaata atagacggg cgttcaaac 
      atcaatatt atcactccg agaccgtat tatagcact 
      gaagcttcg accatttcg ctggaaggg ttgttccaa 
      accgacacc ccccaaaaa ttatccgac aaatttaac 
      ttaaatcaa ctgaaacaa ggtacaaat gatgaggag 
      ctgctggag accggaaat tcgcgttat gtcaatgtg 
      cgggttctt aaggaggac gattacatc acgatgaag 
      gcggaagtg gtcgaagtc actcccaaa ataagcaaa 
      gacataaaa attgtgcca attcaagtg gaaatgtcg 
      cgaaaatta atcgctccg tctgatttt gtgacgaaa 
      gtggagcaa ggcgtgcct aaagtcact ttacaaatt 
      ctcaaaccg caaaattag
    mRNA sequence
    • >TC003876 RA
      ctggtgtct tgagaagtt ttaatagtg tgctaaaga 
      acctcaacg gtggtcatt gtgtcggtg catttgtga 
      ttgtcgata tttaaattc tgtgcagac tttttggac 
      cctttacgt gtacagaat tttaaatca aattcttga 
      ggtggggtt tgaagtgtc attcaagtc tgaaaaagt 
      tcagacatt caattgatc aggatatgt gtgctggtg 
      gtttattgt gattttggt gattttaat gatacgtta 
      acaacgaca aaatgtcga cggatatct gtcgatggt 
      tgttcctcc tgttttttc taacaacat ggaccaaat 
      attcaaatt caaaggaga tccgcgtgg tctgttact 
      acacgaact ggtcagttt acaggcccg gaacagcaa 
      aatttagcc cacaaaata tcaacccct atttatgca 
      cacatctca tttatgcat tcgggggtt ttaccaaag 
      aaaatacgc tcaagccgt tcgataaat accaagata 
      tcgaaaaag gtggttatg caaaattca ccggattga 
      agacataca acaagaact taaagacaa tgctagcca 
      ttggtggct ggaacgaag gttcttcca gattttctc 
      caatggtgg caaaccctg aaaggcgaa aagaactga 
      tcaaaaacg ccatcaagt ttttgagac aaaatcact 
      tcgatggtc ttgatctgg actgggaat atccgagct 
      tccgagatg ggggaaaat caagagata aagacaact 
      acgcccaat tagtccagg aacttcggg aagaatttg 
      accgagaat cggaaaaaa caggaagac cgagattac 
      ttctgacaa tggcagttc ctgcaggaa ttgagtaca 
      ttaacaaag gatacgatg tacccaaac tcaccaagt 
      acctcgatt ggatgaata ttttgagtt acgattacc 
      actctgcct tcgaaccgg ctgttaacc accatgccc 
      cactttacc cacttgaag aaccctctg aatataatt 
      acgatacgg aacttaaca ttgactaca cgattcaac 
      actacttga aaaaaggag ccgatccta gcaaacttg 
      tcctaggaa taccaactt acggccgct cttacactt 
      tatttaacc cagatgcca acgaaattg gagcaccag 
      ctgatgggc ctggagata tgggtgaag caacaagag 
      aaaatggtt atttggcct actacgagg tctgcgagt 
      acattaaaa cccagaact gggaagtag tccaaccaa 
      atccagacg ccatgggtc cgtacgcct tcaaggaca 
      accaatggg tgggatatg acgatgata aaattgcaa 
      ggaaaaaag ccgaatatg tggcagaga aaggccttg 
      gtgggataa tgttttggt cgattgata acgacgatt 
      ttaggggaa attgccacg ggaaacctt accctatta 
      tcgaagcag caaaagaag cgttaattt cagcctatg 
      gattgacag acgagaatt tggtttcac ccccaacca 
      agccaatca aaacaaaaa cgagaaaca ggacccaat 
      cttcatcca aatcaactg acgaaaata gcgaaaaaa 
      agaaaagta caagttcta ttgtgtcca gaagacgca 
      acagaatta aaaccaaat cggaagaac tttcaaaca 
      gccaatcaa aatcccaca ggaaggaaa gccgaagaa 
      caacagaag ggccagttt acagtagtt tagaattag 
      ttacaccca gttatacaa cacctgccc caccctcaa 
      cgccagatc tgggcggag gtttcaaat gtgaagatg 
      aaggtttct acccacacc ctaaagact gtaaaaagt 
      attactggt gtctcagcg ggcctggag agcttggaa 
      tcgttgccc atttgttta cctgtccag caggtctgt 
      atttcaaca aagcggctg attcttgtg attacactc 
      gcaatgttc tgtgcaata aaaaactat caaaggcca 
      caacgacca caactacaa caaccacaa cagaggcca 
      gtactttga aaacatcaa ccgcaagag taccaccta 
      aaattacag cggccacaa gtcgaacta cagtttttc 
      ggacttcga ccacaactg aagcttacg atgacgagt 
      atgaatatg aagacgatg ttgaagaga ataaaaatt 
      cggaagaag atcctaagg ttattaagg aattgctcg 
      atcttatca agaaagctg gaggaattg aagaacttg 
      aaaaacagt tgaaaattc atgaagatg gcagtgctt 
      ccgtttcaa actctgaca caactactc cttcgtcta 
      ttagcaagt cactggtgg aaagggttt taggcaaag 
      gagccaaag ttggtggaa aaaagaatt cttatagtt 
      tcctcaccc gcaacagtc gaggccctc aaaacgagg 
      gtttgaaca cacatgaag ataaagaaa cgacacaag 
      ataaaggaa gaccaaaat acacaacaa tcacaagac 
      aaagatcaa caaataaca aaaatgaag acgaagaag 
      aggaatcct cagacgaag catccaaat ctacgaaaa 
      aacaaccag aatatgtca acattaggc gagcccgag 
      ttagtacta ctacagaag aaccggaag aaaattcaa 
      agagtcaac taaaccgaa ataaaattt tgggagaag 
      aggacgaaa cagaagatg aacaaccaa gtcgtaaga 
      aaacatcag ggccacaat atgttaaca tacggaggc 
      aaaggccat caacaactg aagaaactt caacttcaa 
      aatatactg ttataagaa gagggacaa caactgaac 
      ccgctgaac cagaagaag acgaaacca ctaaaagca 
      atgttgttt caacatcca ccgaaaaaa ttgatttaa 
      aatcaaggt atagcattc ttaggcgag gatcaacga 
      ctgaagcaa ctacaactg agagtggtt caatctctt 
      caacctctt caccaaaga gaagaggaa caacactgc 
      caagtgttc cagaacgga aaagaacga gaggtactt 
      tagctccag ggactacgc catcgtcag aagatacga 
      caacaacaa gatataaga gtattaagc gaggttcaa 
      caagcgaag cacccacaa cagacaaga cattacccg 
      aagattcaa ctctaaagt actccacct tcacccgca 
      cacctgcat ccacccagg ccgccccag cagccaccg 
      aacccgaaa ccgccgtaa ctgttaacg ttcaattac 
      taacaaccc ccgaaagtt taactgtaa aaacaacta 
      gtcttagtt ccacaaaac agtcggaac aatcaaaca 
      ttgaaagta tcggtgaaa gagtctatc agacacaga 
      ctcccttac ttttagaac ctcgcccat tttcaaaaa 
      ctagtactc gaagtccaa caccggtag taaccgaat 
      catccacac gaatcacaa aggtgagtg actcaaatt 
      ataacctcc gactaaagc cgaaactgt cgcaaacgc 
      aaaccgaaa ttattagca ccactactc tcaccaccg 
      aaaaaccaa caccgttta gaactagag caccgtcta 
      gatttaagt taaccacag cgagttacg accaacaag 
      ccacaaagc aagcaaatc gggccagga aacgctttt 
      ccacaacga ccgaattgt attcggaca actacgagg 
      agtttgatt tgagtcgaa cgtacagac cgtcagaaa 
      ttgcagatt tgtcgtcac tgacagctg ttgatttcg 
      tagctttga aggagctca ccagaaaca gcaattctc 
      taagacaga gaaggccta gacctgaaa gtaccactc 
      ccagaacgt catctttta aaagcagac gattgattt 
      cgaacaaaa atgagcaaa atgtggaag atcaagtaa 
      attcaagct ctgataaaa cacacagaa ttcgaggtt 
      tcacaagat cacctcctg ttgtcagta caacaactg 
      aaggaacaa caagacata gtttaagga acaggaaag 
      tcgtccgtc gtttaagac ccacgtcaa gttccaaac 
      tattatcgc aaaattcag acaacaagg aaaacgttg 
      tccctttca aaaaacgtt tggttcgac caaacacag 
      aaacagaaa acttgatcg aaaactcct cgttaaatt 
      cactcttca acaggcgtt taactcgcc ccactgaag 
      ccccaaacg aggaacaaa gcgacgatg tcagcgctg 
      aagaagggg aaaacatta aactatccg aatcaaata 
      tcagagaaa acagcaatg ttaataaca acaacaaca 
      acattctct cgcctgacg atggccaga aagttagac 
      gcaaagttt taaaacgca tcaaaccca aagtagacg 
      acgagaaaa ttgtcacag aaccgaaca ttgtcatca 
      gaacacgaa aaattgtca gaaagttaa caccaaccg 
      aatctacaa ttacttcga ccactgaga caacagtac 
      caggccgta aacgaaaaa ttattcggc gtttgagac 
      ctacaaccg agttgaagg aaaatagta cgcagaaaa 
      cgttgtaca ttaggggaa gaccctttt tggcacatt 
      tcaacaacg aagaatctg gagttgatg caagtacca 
      ttaaaccag actcttcta aatatagta ctcctaaca 
      gaggaacga ctgaagaat cagaagtta cggaacaat 
      ttatagcaa attctgaaa atactgata gttacaaag 
      gaacaactg aagaagcag aagctaaga aacaattga 
      tatcaaatt ctgaaaact cttctcaaa gaactactg 
      atagttaca aaggaacaa ctgaagaag cagatagtt 
      ctactgaac gaactattg atagatcta aatacagta 
      ctcttaaca gaggaacaa tagactcta caagagagg 
      aaagttttg ataaagaga taataacta cagacagag 
      gtccatcaa ggtttagaa gtactactg aaggaacta 
      ttgatagaa ctaaataca gtactctta acaaaggaa 
      caactgaag aaccagaag ttcgggaac actttatat 
      caaattctg acacttcta ctgaaagaa ctattgata 
      gatctaaat acagtactc ttaacagag gaacaacag 
      agtctacaa aagaggaaa aaattgatg aagaaacta 
      taactacaa acaggggac catcaaggt ttagaaatt 
      ctaacactt ctactgaag gaactattg atagatcta 
      aatatagta ctcttaaca gaggaacaa ctgaagaag 
      cagaagtta aggaacaac atatatcaa gttctgatg 
      cttctactg aaggaacta ttgatagat ctaaataca 
      gtactctta acagaggaa caactgaag aagcagaag 
      ttaaggaac aacatatat caaattctg atgcttcta 
      ctgaaggaa ccattgata gatctaaat acagtactc 
      ttaacagag gaacaacag agtcggcaa aagaggaaa 
      aaattgatg aagagataa taagtacaa acagaggtc 
      catcaaggt ttagaattt atcgaccaa ctgttttcc 
      atgatgatg acgaagaag aggaagaag acgattcgt 
      tgaaaactc gaattgtgg aacctttat tcaccgaag 
      aaataacag aaagtaaca agttatcta ataacgcaa 
      ctaacaaaa ctgacgatt tgaataaag aagaagcag 
      atgaggaaa atagtacaa tagaaacta atgaggaaa 
      atagtaccg aagagcata aggatgagg aagataatg 
      aagatatac ctgtgacaa ctgtcaaac cttacatca 
      acccaattc tcaacagac agaaaaata gacccgcct 
      ttcaaagac ctaaactaa caacacaaa agcctttgt 
      cgtctagta caaccagta gaaatagat acaagacct 
      tcggtagat cgacaacag ctcctagta aagaaacga 
      atgaggaaa taacacaag aaaaattcg taccgaaaa 
      atttggatc gaaaccgaa aagtctcaa cttctacca 
      caaccactg aagttgctc cagaaattg aacagacaa 
      cagacagcg ttcaaataa atgatacgg aaagtgata 
      agacaactt tagagagca ttgaagtta ccacattga 
      aagaaacag aggaagtgg ttaatgcta cgactgaaa 
      gtcggacaa ttttggttg aaacaacta cgttaagaa 
      ctactgaaa ctactccaa gtcatcttc ccagaagta 
      cttccagaa ccagaccaa aatttaacg tcccaaaaa 
      gactaacaa cacccgaaa gtagattta gcccaaaac 
      ttcgaactc aaagtacga cccccaaag caccaactt 
      ctctactaa aggataaat ttactcgca aatacacta 
      cgactgaac gaaatgatt tcgttgagg aagaagaca 
      ttccagagg aagacgaag tcgaaaatc aatcttcca 
      cacaaagaa caacacgac ctaaagcta gaccaagta 
      acagaccag acttcagga agtcaacag aagctccaa 
      aaccaaccg aagacttga aaggaattg acactgacg 
      ccgtcaaaa accggaaca aaaatctct tctcgaaaa 
      aacgcaaaa tgaacacac ctttcgcag gccatcccc 
      taaaccagt caattttaa ccacaactc cgaccattt 
      ccgaatcgg tcacaaaac catcaacgg aaccgttcg 
      aaaccactg aatacctca caactttgc accacattt 
      ttgccgaaa ctgaacgtg tcactgaaa atagtttgc 
      caacaacca cgagttcca aaattgaga aattgatcg 
      aagtgaacc gaattgtgg aagtgcacg aaatgaaca 
      acacggaag agagggaca ataaagtgg ttgataaag 
      ttggtgtta tcaatcggg tgacggtgg ttaaggttg 
      ttgacggta attttaacc cggaagata acgaaatta 
      cgaaatcgc caaagttgg atgattttg aaattgcaa 
      ctgttcggg aaataccta atcgggaag atcgcagat 
      acgaacaag ttgccgaaa gtgctgaaa taatagacg 
      ggcgttcaa acatcaata ttatcactc cgagaccgt 
      attatagca ctgaagctt cgaccattt cgctggaag 
      ggttgttcc aaaccgaca ccccccaaa aattatccg 
      acaaattta acttaaatc aactgaaac aaggtacaa 
      atgatgagg agctgctgg agaccggaa attcgcgtt 
      atgtcaatg tgcgggttc ttaaggagg acgattaca 
      tcacgatga aggcggaag tggtcgaag tcactccca 
      aaataagca aagacataa aaattgtgc caattcaag 
      tggaaatgt cgcgaaaat taatcgctc cgtctgatt 
      ttgtgacga aagtggagc aaggcgtgc ctaaagtca 
      ctttacaaa ttctcaaac cgcaaaatt agttaatta 
      ttattgtaa caattatag tattattac gatgttatg 
      tatgtaaat atgagttgt tgtatttta atttaaact 
      gtgtgtgaa taaatcgtt gtaaataat aacgcactt 
      tgtaagata acgcactgt tctttaatc ctcctttct 
      ctcgtgcca taacattgg ttgatttcc ttagtgttt 
      gtatggcca gtgagtcct ttcttattg taattatta 
      atggacgtt taaatatac catattaat tatt
    The data is licensed under a Creative Commons Attribution 3.0 Unported License. (CC-BY) CC-BY