| General information | |||
| TC002905 | Gene
The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser. |
NC_007418.3: 6798278..6816375 | |
| Sequence information | |||
| Transcripts / Proteins (3) | Get mRNA sequence
Get CDS sequence Get protein sequence |
||
| Ortholog information (from OrthoDB)
The information about the homolog genes in Drosophila
is provided by OrthoDB http://www.orthodb.org/.
The homologs are sorted according to their similarity score. For an orthology statement additional
analysis are required. | |||
| Closest fly homologs |
|
TC002905 | |
Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.
| General information | ||||
| iB_03466 | iB fragment
The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser. |
Get FastA Get primers |
||
Usually 10 injected animals
Pupal injection procedure
Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.
3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.
9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.
11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.
Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.
13 dpi: Egg productivity and Ovary analysis
The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi).
In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.
14 dpi: Analysis of embryonic musculature and early embryonic development
Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.
15 dpi: Analysis of larval instar 1 cuticle
Offspring of injected females were analysed and cuticle phenotypes were annotated.
22 dpi: Stink gland analysis
Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.
Terms used in the pupal injection procedure
- larval pantagmatic defects
- At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
- empty eggs
- Just empty shells are visible, no cuticle has been developed.
- strong defects
- L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
- strongly fragmented (cuticle crumbs)
- No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
- cuticle remnants (with unidentifiable segments)
- Segments or parts of appendages are recognizable, but identity is not clear.
- cuticle remnants (with some identifiable segments)
- At least one segment or appendage is clearly regonizable.
- number of eggs on slide
- affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
For the embryonic muscle analysis the hatched as well as the not hatched were analysed. - total number of affected eggs/embryos/larvae
- Summary of all different phenotypes/ phenotypic series which were annotated.
- inside-out
- The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
- starved
- Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
- eclosion not fulfilled
- The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
Metamorphosis and survival
Lethality 11 days after pupal injection: 50.0% (includes death as pupa, adult)
eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 4 (3 dpi)Days post injection
adult lethality - Number of animals showing the phenotype: 1 (9 dpi)
Days post injection
Analysis of larval stage 1 cuticle
number of eggs/embryos/larvae on slide: < 20
Usually 10 injected animals
Larval injection procedure
Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.
11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.
16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.
19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.
22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.
41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).
Terms used in the larval injection procedure
- pupal/ adult pantagmatic defects
- At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
- pupal molt not fulfilled
- The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
- eclosion not fulfilled
- The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
- starved
- Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
Metamorphosis and survival
Lethalities 11 days after larval injection: 0.0% (includes death as larva, prepupa, pupa)
Lethalities 22 days after larval injection: 0.0% (includes death as larva, prepupa, pupa, adult)
- >TC002905 RA
MEDKRGHRF GGSKVSEIA NRFQAKSSH SEEIIAPIK TKKIASCPN ELVEEISDV NVIRTESHV TRFNSARAL FEKLGEENR NNRDKFAPL QCTKSASDI CDPKTRSNL SHEDNFDSA KHGIRSLSP NQRGALETC PVAKSNNVV PSSENNVII ANQTKPLVK PEKPEKPQR KFNNKELIE KQRNWTSHF SKSRSPRYS SDPNKTEKL AVNNGDSNT THEHKVASR SASFSNRIT GSVANENFR RNDVIRKER PASVIPTMC SNNNNETSP TRVAPCEDM HRRKERNSM ILGETERPI ETFPDDVPT VAPREFAHS VTTNTDNKE TKKRKICDQ SEEHFFVPS EVNDNKDVS RESLSATSG SLSSLSPPT SPGKLKSEI EKQEDEGNE KSFLSDVTD SAFCQTDDR LDVSELEPL PLEEGDPHL KAKAKFLYE SAETKLIST DKEPEIKLT DAEKEALYA VPCKNRRQE KCHIPPKPD VLQSIKCET DLNNTAVFA LQEHPNNKR THMVCDKSN EEAKKRCFK GEGVPRSES PLLDFENES EYATIDDIE ADSMTPTEE EHLLSTKIS EKRLVSSRH DLLSDEEAQ EVTRLLNSK SPLTDEWAT ESSLFALNE QPVPPTNSS EPTFVNHYS DVAPVSEKL FAHLEEKDK ADIDEEAND FSQLDSIAF IDSSPPNES VESPKPRRK SKEVENKLD REKSDYAPE SVPIVGEEN GVHYYEDGH FWMEVPGLL PESEEEDDE SACYTHIPK PTKVAFSTE PMKVYSTFS VTEYDRRNE DVDPVAASA EYELEKRVE KMDVFPVEL IKGSEGLGL SIIGMGVGA DAGLEKLGI FVKTITANG AAAKDGRIK VNDQIIEVD GKSLVGVTQ AYAASVLRN TSGLVKFSI GRERDPENS EVAQLIRQS LQADREREE RRQKALEME QQQSDASTV PLTGSANTS VSDGPNSPL VSAENSMDV EQSSDIDSL KVLLQELME QNGIKPDDS EKLAQLNQK LKETERILV TAKKEIQTY QNMLEQSQS QYLVMEKKY TKAKQLLRE FQHRELDMI HREDFYQQL LQEKDTEYN ALVKNLKDR IIILEQDLL EAQQKAGLP CVLPNDNLN LKQLTPQMT RRVPPKPLY NALETNLSD TEISDHSPD DDKTATVER KLPLKEELD RVVPQHELL DISVNKSKA ELANRGSLA NRQLPSAKK GSLSNSSSS DYGLDDSYN SGDEVNCCN GRTTNSNNL YSQHTRCQV QANPETQHD FQYNKVQKP VYASYNKRV DPTPVYAKV QKDSSHSDY TNPDSGIVK KGIGMGPPP SLAEQLKQV LSEREKRFS SDTLNSSCE ELTERSKHN AAQHLLEEI RQAVNEANA KVKKVVPVT LSPPGSTPW QHQGSMLPT PPSPSSLSS GSVSPSKHD ASWVTTDLS LSSCSISSD KRGSQYWQS TPISEWSKD QVSQWLLGI GMENHIPKF VELDVNGQA LLLLTSADF KILGIASDD KSYLKRKIK ELKIQNEKE RKQMERNRK EKEKLLRKA EKANKKK
- >TC002905 RB
MEDKRGHRF GGSKVSEIA NRFQAKSSH SEEIIAPIK TKKIASCPN ELVEEISDV NVIRTESHV TRFNSARAL FEKLGEENR NNRDKFAPL QCTKSASDI CDPKTRSNL SHEDNFDSA KHGIRSLSP NQRGALETC PVAKSNNVV PSSENNVII ANQTKPLVK PEKPEKPQR KFNNKELIE KQRNWTSHF SKSRSPRYS SDPNKTEKL AVNNGDSNT THEHKVASR SASFSNRIT GSVANENFR RNDVIRKER PASVIPTMC SNNNNETSP TRVAPCEDM HRRKERNSM ILGETERPI ETFPDDVPT VAPREFAHS VTTNTDNKE TKKRKICDQ SEEHFFVPS EVNDNKDVS RESLSATSG SLSSLSPPT SPGKLKSEI EKQEDEGNE KSFLSDVTD SAFCQTDDR LDVSELEPL PLEEGDPHL KAKAKFLYE SAETKLIST DKEPEIKLT DAEKEALYA VPCKNRRQE KCHIPPKPD VLQSIKCET DLNNTAVFA LQEHPNNKR THMVCDKSN EEAKKRCFK GEGVPRSES PLLDFENES EYATIDDIE ADSMTPTEE EHLLSTKIS EKRLVSSRH DLLSDEEAQ EVTRLLNSK SPLTDEWAT ESSLFALNE QPVPPTNSS EPTFVNHYS DVAPVSEKL FAHLEEKDK ADIDEEAND FSQLDSIAF IDSSPPNES VESPKPRRK SKEENKLDR EKSDYAPES VPIVGEENG VHYYEDGHF WMEVPGLLP ESEEEDDES ACYTHIPKP TKVAFSTEP MKVYSTFSV TEYDRRNED VDPVAASAE YELEKRVEK MDVFPVELI KGSEGLGLS IIGMGVGAD AGLEKLGIF VKTITANGA AAKDGRIKV NDQIIEVDG KSLVGVTQA YAASVLRNT SGLVKFSIG RERDPENSE VAQLIRQSL QADREREER RQKALEMEQ QQSDASTVP LTGSANTSV SDGPNSPLV SAENSMDVE QSSDIDSLK VLLQELMEQ NGIKPDDSE KLAQLNQKL KETERILVT AKKEIQTYQ NMLEQSQSQ YLVMEKKYT KAKQLLREF QHRELDMIH REDFYQQLL QEKDTEYNA LVKNLKDRI IILEQDLLE AQQKAGLPC VLPNDNLNL KQLTPQMTR RVPPKPLYN ALETNLSDT EISDHSPDD DKTATVERK LPLKEELDR VVPQHELLD ISVNKSKAE LANRGSLAN RQLPSAKKG SLSNSSSSD YGLDDSYNS GDEVNCCNG RTTNSNNLY SQHTRCQVQ ANPETQHDF QYNKVQKPV YASYNKRVD PTPVYAKVQ KDSSHSDYT NPDSGIVKK GIGMGPPPS LAEQLKQVL SEREKRFSS DTLNSSCEE LTERSKHNA AQHLLEEIR QAVNEANAK VKKVVPVTL SPPGSTPWQ HQGSMLPTP PSPSSLSSG SVSPSKHDA SWVTTDLSL SSCSISSDK RGSQYWQST PISEWSKDQ VSQWLLGIG MENHIPKFV ELDVNGQAL LLLTSADFK ILGIASDDK SYLKRKIKE LKIQNEKER KQMERNRKE KEKLLRKAE KANKKK
- >TC002905 RC
MEDKRGHRF GGSKVSEIA NRFQAKSSH SEEIIAPIK TKKIASCPN ELVEEISDV NVIRTESHV TRFNSARAL FEKLGEENR NNRDKFAPL QCTKSASDI CDPKTRSNL SHEDNFDSA KHGIRSLSP NQRGALETC PVAKSNNVV PSSENNVII ANQTKPLVK PEKPEKPQR KFNNKELIE KQRNWTSHF SKSRSPRYS SDPNKTEKL AVNNGDSNT THEHKVASR SASFSNRIT GSVANENFR RNDVIRKER PASVIPTMC SNNNNETSP TRVAPCEDM HRRKERNSM ILGETERPI ETFPDDVPT VAPREFAHS VTTNTDNKE TKKRKICDQ SEEHFFVPS EVNDNKDVS RESLSATSG SLSSLSPPT SPGKLKSEI EKQEDEGNE KSFLSDVTD SAFCQTDDR LDVSELEPL PLEEGDPHL KAKAKFLYE SAETKLIST DKEPEIKLT DAEKEALYA VPCKNRRQE KCHIPPKPD VLQSIKCET DLNNTAVFA LQEHPNNKR THMVCDKSN EEAKKRCFK GEGVPRSES PLLDFENES EYATIDDIE ADSMTPTEE EHLLSTKIS EKRLVSSRH DLLSDEEAQ EVTRLLNSK SPLTDEWAT ESSLFALNE QPVPPTNSS EPTFVNHYS DVAPVSEKL FAHLEEKDK ADIDEEAND FSQLDSIAF IDSSPPNES VESPKPRRK SKEVENKLD REKSDYAPE SVPIVGEEN GVHYYEDGH FWMEVPGLL PESEEEDDE SACYTHIPK PTKVAFSTE PMKVYSTFS VTEYDRRNE DVDPVAASA EYELEKRVE KMDVFPVEL IKGSEGLGL SIIGMGVGA DAGLEKLGI FVKTITANG AAAKDGRIK VNDQIIEVD GKSLVGVTQ AYAASVLRN TSGLVKFSI GRERDPENS EVAQLIRQS LQADREREE RRQKALEME QQQSDASTV PLTGSANTS VSDGPNSPL VSAENSMDV EQSSDIDSL KVLLQELME QNGIKPDDS EKLAQLNQK LKETERILV TAKKEIQTY QNMLEQSQS QYLVMEKKY TKAKQLLRE FQHRELDMI HREDFYQQL LQEKDTEYN ALVKNLKDR IIILEQDLL EAQQKAGLP CVLPNDNLN LKQLTPQMT RRVPPKPLY NALETNLSD TEISDHSPD DDKTATVER KLPLKEELD RVVPQHELL DISVNKSKA ELANRGSLA NRQLPSAKK GSLSNSSSS DYGLDDSYN SGDEVNCCN GRTTNSNNL YSQHTRCQV QANPETQHD FQYNKVQKP VYASYNKRV DPTPVYAKV QKDSSHSDY TNPDSGIVK KGIGMGPPP SLAEQLKQV LSEREKRFS SDTLNSSCE ELTERSKHN AAQHLLEEI RQAVNEANA KGSTPWQHQ GSMLPTPPS PSSLSSGSV SPSKHDASW VTTDLSLSS CSISSDKRG SQYWQSTPI SEWSKDQVS QWLLGIGME NHIPKFVEL DVNGQALLL LTSADFKIL GIASDDKSY LKRKIKELK IQNEKERKQ MERNRKEKE KLLRKAEKA NKKK
- >TC002905 RA
atggaggac aagcggggc catcgcttt ggcggctcc aaagtctca gaaatagcg aaccgattc caagcaaaa tcctcccac agcgaggag attatcgcc cctataaaa accaaaaag atcgcttcg tgcccaaac gagctagtt gaagaaata tctgacgta aatgtaatc cgcacagaa tcgcacgtg acgaggttc aacagcgct cgagcactt tttgagaaa ctaggcgaa gagaaccgc aacaatcgc gataaattc gcacctctc caatgtacg aaaagcgct tccgacatt tgtgatccc aaaaccagg agtaactta tctcacgaa gataacttt gactcggcc aaacacggt attagatct ctatcgccc aaccaaaga ggggccctt gaaacatgt ccagtggca aagagcaac aatgttgtg cctagttcc gagaataac gtcattata gcgaatcaa accaagccg ctagtgaag ccagaaaaa cccgaaaaa ccccagcga aaattcaac aataaggaa ttgatcgag aagcaaagg aattggact tcacacttc tccaagtca cgcagtccg cgctacagc agtgatccc aacaaaacg gaaaagcta gctgtgaat aacggcgat tcaaacaca acacatgag cacaaggta gctagcaga agtgcatct ttcagtaat cgaattaca ggatcggta gctaacgaa aactttcga cgaaatgac gttattcgg aaggaacgt ccagcttcg gttattccg actatgtgt agtaacaat aacaatgag acaagtccc acaagggtg gcaccttgt gaagatatg cacaggcga aaagagagg aacagtatg atattaggg gagactgaa agaccaatt gaaacattt cctgatgat gtgccaact gtagcgcct agggagttc gctcattca gtcactaca aacacggat aataaagaa acaaagaag cggaaaatt tgtgatcaa agtgaagaa cactttttt gttccttcg gaagtaaac gataataag gacgtcagt cgggagagt ttatcagca acgtctggc agcttatcg tccctaagc cctcccaca agccccgga aagttgaaa tcagaaatc gaaaaacaa gaagatgaa gggaacgag aaatctttt ctttcagac gttaccgac tccgcgttt tgccaaacg gacgatcgg ttggatgtt tcggaactt gaaccactt ccccttgaa gagggcgat ccacatttg aaggcaaaa gctaaattt ttgtacgaa agtgcagaa actaaatta atcagcact gataaggag ccagagatt aaattaacc gatgccgag aaagaggcg ctttatgct gtgccgtgt aagaatcgc agacaagaa aaatgtcac attccaccc aagccagat gtcttgcaa tcgattaaa tgcgagacg gatctaaat aatacggca gtgtttgct ttacaagaa caccccaat aacaaacgg acgcatatg gtgtgtgat aaaagtaat gaagaggcg aaaaagagg tgttttaaa ggggagggt gttcctaga tcggagagc cctttgttg gattttgaa aatgagagt gaatatgct accattgat gatattgaa gccgattcg atgactccg actgaagaa gaacatttg ttaagcaca aaaatttcg gaaaaacgc ttagtgtca agcagacac gaccttctc tcagacgaa gaggcgcaa gaagttaca agattgcta aattctaaa agtccacta accgacgaa tgggcaaca gaatcgtca ctgtttgct ctaaatgag cagccagtg ccaccgacc aattcgtcc gaaccaaca tttgtaaat cactactcg gacgtagct cctgtctca gaaaaatta tttgctcac ttagaagaa aaagataag gctgatatt gacgaagaa gcgaacgat ttctcacaa ctcgactcc attgctttc atagatagc tcaccgcca aacgagtca gttgaatcc ccaaaacct cgaagaaaa tcaaaagaa gtagagaat aagttagat agggaaaaa agtgactac gcccccgag tcggtcccc atcgtgggg gaggaaaac ggcgtccac tactacgaa gacgggcat ttttggatg gaggttcca ggtctcctc ccagaatcc gaggaagaa gacgacgaa tccgcttgt tacacccat attcccaaa cccacaaag gtcgcattt tccaccgaa cccatgaag gtctactcc acgttcagc gtaacagaa tacgaccga cggaatgaa gacgtcgat cccgtcgca gcttccgca gaatacgag cttgagaaa cgagtcgaa aaaatggat gtttttccg gtcgagctt atcaaaggt tcggaaggc cttggactc agtattatc gggatgggg gttggggcg gatgcgggt ttggaaaag ctgggcata tttgtgaag actataaca gcaaatggg gctgccgca aaagacggg agaattaaa gttaatgac cagattatt gaagtcgat gggaaaagt ctggttggt gttacgcaa gcttacgct gcgagtgtt ttacggaac acttccgga cttgtcaaa tttagtatt gggcgggag agggatccg gaaaatagt gaggtggct cagcttata cgacaatcg ctgcaggcg gatagggag agggaggag aggaggcag aaggcttta gagatggag caacagcag agtgatgct agcacggtg ccattaaca ggttctgca aacactagt gtatcagac ggtccaaac agtccttta gtgagcgct gaaaattca atggacgta gaacagagc tcagacatt gactcgtta aaagtgctt ctacaagaa ttaatggag caaaacggc ataaaaccg gacgactcc gaaaagttg gctcagtta aatcaaaag ctcaaggaa acggaacga attttagta acggcgaaa aaggagatc cagacctat cagaatatg ttggaacag tctcagtcc caatacctc gtaatggaa aagaaatac actaaagca aaacagtta cttcgagaa ttccaacac cgtgagttg gacatgatc catcgggag gatttctac caacaactt ttgcaagaa aaggacacg gaatacaac gctttggtg aaaaattta aaggaccgg ataataatc ctagagcag gatttgctc gaagctcaa caaaaagct ggcttgcct tgcgttctc cccaacgat aatctcaac ctaaagcag ctgacgccc caaatgacc agacgcgtt ccccccaag cccttatac aacgcttta gaaacgaat ctgtcagac acggaaatt tccgaccac agtccggac gatgataag actgcaaca gttgagaga aagctccct ttgaaggag gagctcgac cgggttgtt cctcaacac gaactgctg gacatttct gtcaataag agcaaggcg gaattggca aacaggggt tccttggcc aataggcaa ctgccaagt gcgaaaaaa ggttccttg agtaatagc agcagctcg gattacggc ttagacgat agttacaat tcaggggac gaagtcaat tgttgtaac ggacgtact acgaactct aataattta tattcgcaa catacgagg tgccaggtg caagctaac ccagaaacg caacacgat tttcaatac aacaaagta caaaaacca gtttacgct tcatacaat aaaagggtg gatcccacg ccagtttac gcaaaagtt caaaaggat tctagtcat tcggattat acgaacccg gattcgggg attgtcaaa aaggggatc ggcatggga cctccgcct tcgcttgcc gaacaactg aaacaagtt ttgtcagag cgggagaag cggttcagc tctgacact ctgaatagt tcctgtgaa gaattgacg gaaaggtcg aaacacaac gccgcccag catttgctc gaggagatc cggcaagct gtgaacgag gcaaatgcg aaagtaaag aaagttgtg cccgttaca ttatcaccc ccaggtagt actccatgg caacatcaa ggaagtatg ttacctaca cctccgtct ccgtcgagt ttgtcgtca gggtccgtt tcaccctca aaacacgac gcctcgtgg gttacaaca gatctcagt ctgtcctcg tgtagtatt agcagcgac aaaagaggg tcgcagtat tggcagtcg acgcctatt tcagaatgg agcaaagac caggtctcc cagtggctg cttgggatt gggatggag aaccatatt ccaaagttc gtagagttg gacgtcaat gggcaagct ctcctcttg ttgacgtct gcggatttc aaaattctc ggtatcgca agtgacgat aaaagctac ttgaagcga aaaataaaa gaactgaaa atacagaac gagaaggag cgcaaacag atggaacgg aatagaaaa gagaaagag aagctttta cggaaagcg gagaaagca aataagaaa aagtaa
- >TC002905 RB
atggaggac aagcggggc catcgcttt ggcggctcc aaagtctca gaaatagcg aaccgattc caagcaaaa tcctcccac agcgaggag attatcgcc cctataaaa accaaaaag atcgcttcg tgcccaaac gagctagtt gaagaaata tctgacgta aatgtaatc cgcacagaa tcgcacgtg acgaggttc aacagcgct cgagcactt tttgagaaa ctaggcgaa gagaaccgc aacaatcgc gataaattc gcacctctc caatgtacg aaaagcgct tccgacatt tgtgatccc aaaaccagg agtaactta tctcacgaa gataacttt gactcggcc aaacacggt attagatct ctatcgccc aaccaaaga ggggccctt gaaacatgt ccagtggca aagagcaac aatgttgtg cctagttcc gagaataac gtcattata gcgaatcaa accaagccg ctagtgaag ccagaaaaa cccgaaaaa ccccagcga aaattcaac aataaggaa ttgatcgag aagcaaagg aattggact tcacacttc tccaagtca cgcagtccg cgctacagc agtgatccc aacaaaacg gaaaagcta gctgtgaat aacggcgat tcaaacaca acacatgag cacaaggta gctagcaga agtgcatct ttcagtaat cgaattaca ggatcggta gctaacgaa aactttcga cgaaatgac gttattcgg aaggaacgt ccagcttcg gttattccg actatgtgt agtaacaat aacaatgag acaagtccc acaagggtg gcaccttgt gaagatatg cacaggcga aaagagagg aacagtatg atattaggg gagactgaa agaccaatt gaaacattt cctgatgat gtgccaact gtagcgcct agggagttc gctcattca gtcactaca aacacggat aataaagaa acaaagaag cggaaaatt tgtgatcaa agtgaagaa cactttttt gttccttcg gaagtaaac gataataag gacgtcagt cgggagagt ttatcagca acgtctggc agcttatcg tccctaagc cctcccaca agccccgga aagttgaaa tcagaaatc gaaaaacaa gaagatgaa gggaacgag aaatctttt ctttcagac gttaccgac tccgcgttt tgccaaacg gacgatcgg ttggatgtt tcggaactt gaaccactt ccccttgaa gagggcgat ccacatttg aaggcaaaa gctaaattt ttgtacgaa agtgcagaa actaaatta atcagcact gataaggag ccagagatt aaattaacc gatgccgag aaagaggcg ctttatgct gtgccgtgt aagaatcgc agacaagaa aaatgtcac attccaccc aagccagat gtcttgcaa tcgattaaa tgcgagacg gatctaaat aatacggca gtgtttgct ttacaagaa caccccaat aacaaacgg acgcatatg gtgtgtgat aaaagtaat gaagaggcg aaaaagagg tgttttaaa ggggagggt gttcctaga tcggagagc cctttgttg gattttgaa aatgagagt gaatatgct accattgat gatattgaa gccgattcg atgactccg actgaagaa gaacatttg ttaagcaca aaaatttcg gaaaaacgc ttagtgtca agcagacac gaccttctc tcagacgaa gaggcgcaa gaagttaca agattgcta aattctaaa agtccacta accgacgaa tgggcaaca gaatcgtca ctgtttgct ctaaatgag cagccagtg ccaccgacc aattcgtcc gaaccaaca tttgtaaat cactactcg gacgtagct cctgtctca gaaaaatta tttgctcac ttagaagaa aaagataag gctgatatt gacgaagaa gcgaacgat ttctcacaa ctcgactcc attgctttc atagatagc tcaccgcca aacgagtca gttgaatcc ccaaaacct cgaagaaaa tcaaaagaa gagaataag ttagatagg gaaaaaagt gactacgcc cccgagtcg gtccccatc gtgggggag gaaaacggc gtccactac tacgaagac gggcatttt tggatggag gttccaggt ctcctccca gaatccgag gaagaagac gacgaatcc gcttgttac acccatatt cccaaaccc acaaaggtc gcattttcc accgaaccc atgaaggtc tactccacg ttcagcgta acagaatac gaccgacgg aatgaagac gtcgatccc gtcgcagct tccgcagaa tacgagctt gagaaacga gtcgaaaaa atggatgtt tttccggtc gagcttatc aaaggttcg gaaggcctt ggactcagt attatcggg atgggggtt ggggcggat gcgggtttg gaaaagctg ggcatattt gtgaagact ataacagca aatggggct gccgcaaaa gacgggaga attaaagtt aatgaccag attattgaa gtcgatggg aaaagtctg gttggtgtt acgcaagct tacgctgcg agtgtttta cggaacact tccggactt gtcaaattt agtattggg cgggagagg gatccggaa aatagtgag gtggctcag cttatacga caatcgctg caggcggat agggagagg gaggagagg aggcagaag gctttagag atggagcaa cagcagagt gatgctagc acggtgcca ttaacaggt tctgcaaac actagtgta tcagacggt ccaaacagt cctttagtg agcgctgaa aattcaatg gacgtagaa cagagctca gacattgac tcgttaaaa gtgcttcta caagaatta atggagcaa aacggcata aaaccggac gactccgaa aagttggct cagttaaat caaaagctc aaggaaacg gaacgaatt ttagtaacg gcgaaaaag gagatccag acctatcag aatatgttg gaacagtct cagtcccaa tacctcgta atggaaaag aaatacact aaagcaaaa cagttactt cgagaattc caacaccgt gagttggac atgatccat cgggaggat ttctaccaa caacttttg caagaaaag gacacggaa tacaacgct ttggtgaaa aatttaaag gaccggata ataatccta gagcaggat ttgctcgaa gctcaacaa aaagctggc ttgccttgc gttctcccc aacgataat ctcaaccta aagcagctg acgccccaa atgaccaga cgcgttccc cccaagccc ttatacaac gctttagaa acgaatctg tcagacacg gaaatttcc gaccacagt ccggacgat gataagact gcaacagtt gagagaaag ctccctttg aaggaggag ctcgaccgg gttgttcct caacacgaa ctgctggac atttctgtc aataagagc aaggcggaa ttggcaaac aggggttcc ttggccaat aggcaactg ccaagtgcg aaaaaaggt tccttgagt aatagcagc agctcggat tacggctta gacgatagt tacaattca ggggacgaa gtcaattgt tgtaacgga cgtactacg aactctaat aatttatat tcgcaacat acgaggtgc caggtgcaa gctaaccca gaaacgcaa cacgatttt caatacaac aaagtacaa aaaccagtt tacgcttca tacaataaa agggtggat cccacgcca gtttacgca aaagttcaa aaggattct agtcattcg gattatacg aacccggat tcggggatt gtcaaaaag gggatcggc atgggacct ccgccttcg cttgccgaa caactgaaa caagttttg tcagagcgg gagaagcgg ttcagctct gacactctg aatagttcc tgtgaagaa ttgacggaa aggtcgaaa cacaacgcc gcccagcat ttgctcgag gagatccgg caagctgtg aacgaggca aatgcgaaa gtaaagaaa gttgtgccc gttacatta tcaccccca ggtagtact ccatggcaa catcaagga agtatgtta cctacacct ccgtctccg tcgagtttg tcgtcaggg tccgtttca ccctcaaaa cacgacgcc tcgtgggtt acaacagat ctcagtctg tcctcgtgt agtattagc agcgacaaa agagggtcg cagtattgg cagtcgacg cctatttca gaatggagc aaagaccag gtctcccag tggctgctt gggattggg atggagaac catattcca aagttcgta gagttggac gtcaatggg caagctctc ctcttgttg acgtctgcg gatttcaaa attctcggt atcgcaagt gacgataaa agctacttg aagcgaaaa ataaaagaa ctgaaaata cagaacgag aaggagcgc aaacagatg gaacggaat agaaaagag aaagagaag cttttacgg aaagcggag aaagcaaat aagaaaaag taa
- >TC002905 RC
atggaggac aagcggggc catcgcttt ggcggctcc aaagtctca gaaatagcg aaccgattc caagcaaaa tcctcccac agcgaggag attatcgcc cctataaaa accaaaaag atcgcttcg tgcccaaac gagctagtt gaagaaata tctgacgta aatgtaatc cgcacagaa tcgcacgtg acgaggttc aacagcgct cgagcactt tttgagaaa ctaggcgaa gagaaccgc aacaatcgc gataaattc gcacctctc caatgtacg aaaagcgct tccgacatt tgtgatccc aaaaccagg agtaactta tctcacgaa gataacttt gactcggcc aaacacggt attagatct ctatcgccc aaccaaaga ggggccctt gaaacatgt ccagtggca aagagcaac aatgttgtg cctagttcc gagaataac gtcattata gcgaatcaa accaagccg ctagtgaag ccagaaaaa cccgaaaaa ccccagcga aaattcaac aataaggaa ttgatcgag aagcaaagg aattggact tcacacttc tccaagtca cgcagtccg cgctacagc agtgatccc aacaaaacg gaaaagcta gctgtgaat aacggcgat tcaaacaca acacatgag cacaaggta gctagcaga agtgcatct ttcagtaat cgaattaca ggatcggta gctaacgaa aactttcga cgaaatgac gttattcgg aaggaacgt ccagcttcg gttattccg actatgtgt agtaacaat aacaatgag acaagtccc acaagggtg gcaccttgt gaagatatg cacaggcga aaagagagg aacagtatg atattaggg gagactgaa agaccaatt gaaacattt cctgatgat gtgccaact gtagcgcct agggagttc gctcattca gtcactaca aacacggat aataaagaa acaaagaag cggaaaatt tgtgatcaa agtgaagaa cactttttt gttccttcg gaagtaaac gataataag gacgtcagt cgggagagt ttatcagca acgtctggc agcttatcg tccctaagc cctcccaca agccccgga aagttgaaa tcagaaatc gaaaaacaa gaagatgaa gggaacgag aaatctttt ctttcagac gttaccgac tccgcgttt tgccaaacg gacgatcgg ttggatgtt tcggaactt gaaccactt ccccttgaa gagggcgat ccacatttg aaggcaaaa gctaaattt ttgtacgaa agtgcagaa actaaatta atcagcact gataaggag ccagagatt aaattaacc gatgccgag aaagaggcg ctttatgct gtgccgtgt aagaatcgc agacaagaa aaatgtcac attccaccc aagccagat gtcttgcaa tcgattaaa tgcgagacg gatctaaat aatacggca gtgtttgct ttacaagaa caccccaat aacaaacgg acgcatatg gtgtgtgat aaaagtaat gaagaggcg aaaaagagg tgttttaaa ggggagggt gttcctaga tcggagagc cctttgttg gattttgaa aatgagagt gaatatgct accattgat gatattgaa gccgattcg atgactccg actgaagaa gaacatttg ttaagcaca aaaatttcg gaaaaacgc ttagtgtca agcagacac gaccttctc tcagacgaa gaggcgcaa gaagttaca agattgcta aattctaaa agtccacta accgacgaa tgggcaaca gaatcgtca ctgtttgct ctaaatgag cagccagtg ccaccgacc aattcgtcc gaaccaaca tttgtaaat cactactcg gacgtagct cctgtctca gaaaaatta tttgctcac ttagaagaa aaagataag gctgatatt gacgaagaa gcgaacgat ttctcacaa ctcgactcc attgctttc atagatagc tcaccgcca aacgagtca gttgaatcc ccaaaacct cgaagaaaa tcaaaagaa gtagagaat aagttagat agggaaaaa agtgactac gcccccgag tcggtcccc atcgtgggg gaggaaaac ggcgtccac tactacgaa gacgggcat ttttggatg gaggttcca ggtctcctc ccagaatcc gaggaagaa gacgacgaa tccgcttgt tacacccat attcccaaa cccacaaag gtcgcattt tccaccgaa cccatgaag gtctactcc acgttcagc gtaacagaa tacgaccga cggaatgaa gacgtcgat cccgtcgca gcttccgca gaatacgag cttgagaaa cgagtcgaa aaaatggat gtttttccg gtcgagctt atcaaaggt tcggaaggc cttggactc agtattatc gggatgggg gttggggcg gatgcgggt ttggaaaag ctgggcata tttgtgaag actataaca gcaaatggg gctgccgca aaagacggg agaattaaa gttaatgac cagattatt gaagtcgat gggaaaagt ctggttggt gttacgcaa gcttacgct gcgagtgtt ttacggaac acttccgga cttgtcaaa tttagtatt gggcgggag agggatccg gaaaatagt gaggtggct cagcttata cgacaatcg ctgcaggcg gatagggag agggaggag aggaggcag aaggcttta gagatggag caacagcag agtgatgct agcacggtg ccattaaca ggttctgca aacactagt gtatcagac ggtccaaac agtccttta gtgagcgct gaaaattca atggacgta gaacagagc tcagacatt gactcgtta aaagtgctt ctacaagaa ttaatggag caaaacggc ataaaaccg gacgactcc gaaaagttg gctcagtta aatcaaaag ctcaaggaa acggaacga attttagta acggcgaaa aaggagatc cagacctat cagaatatg ttggaacag tctcagtcc caatacctc gtaatggaa aagaaatac actaaagca aaacagtta cttcgagaa ttccaacac cgtgagttg gacatgatc catcgggag gatttctac caacaactt ttgcaagaa aaggacacg gaatacaac gctttggtg aaaaattta aaggaccgg ataataatc ctagagcag gatttgctc gaagctcaa caaaaagct ggcttgcct tgcgttctc cccaacgat aatctcaac ctaaagcag ctgacgccc caaatgacc agacgcgtt ccccccaag cccttatac aacgcttta gaaacgaat ctgtcagac acggaaatt tccgaccac agtccggac gatgataag actgcaaca gttgagaga aagctccct ttgaaggag gagctcgac cgggttgtt cctcaacac gaactgctg gacatttct gtcaataag agcaaggcg gaattggca aacaggggt tccttggcc aataggcaa ctgccaagt gcgaaaaaa ggttccttg agtaatagc agcagctcg gattacggc ttagacgat agttacaat tcaggggac gaagtcaat tgttgtaac ggacgtact acgaactct aataattta tattcgcaa catacgagg tgccaggtg caagctaac ccagaaacg caacacgat tttcaatac aacaaagta caaaaacca gtttacgct tcatacaat aaaagggtg gatcccacg ccagtttac gcaaaagtt caaaaggat tctagtcat tcggattat acgaacccg gattcgggg attgtcaaa aaggggatc ggcatggga cctccgcct tcgcttgcc gaacaactg aaacaagtt ttgtcagag cgggagaag cggttcagc tctgacact ctgaatagt tcctgtgaa gaattgacg gaaaggtcg aaacacaac gccgcccag catttgctc gaggagatc cggcaagct gtgaacgag gcaaatgcg aaaggtagt actccatgg caacatcaa ggaagtatg ttacctaca cctccgtct ccgtcgagt ttgtcgtca gggtccgtt tcaccctca aaacacgac gcctcgtgg gttacaaca gatctcagt ctgtcctcg tgtagtatt agcagcgac aaaagaggg tcgcagtat tggcagtcg acgcctatt tcagaatgg agcaaagac caggtctcc cagtggctg cttgggatt gggatggag aaccatatt ccaaagttc gtagagttg gacgtcaat gggcaagct ctcctcttg ttgacgtct gcggatttc aaaattctc ggtatcgca agtgacgat aaaagctac ttgaagcga aaaataaaa gaactgaaa atacagaac gagaaggag cgcaaacag atggaacgg aatagaaaa gagaaagag aagctttta cggaaagcg gagaaagca aataagaaa aagtaa
- >TC002905 RA
cgcagattg tgcgatttc atcgaatcg tgttttgtg aagggtggt gaattttga ctgatgcaa actaatgga taatagctt attttgaca gtaatgaat aaacacaaa gctgtcgta aataaaaac atgtaaaaa ttgtgcgtc attgttcat tttctgcgg tcacctgtg catattctt gcgttaaaa ataaaagta tttatgaaa acatggcat gtataatag tgacatttg ggcgtcgtt gtaaaaaac gaatacagt gatggatta ataatcgac ttttctaat ggattaaaa tctcccctc acgatttaa acacggctg ctacctggc gccgttatg gaggacaag cggggccat cgctttggc ggctccaaa gtctcagaa atagcgaac cgattccaa gcaaaatcc tcccacagc gaggagatt atcgcccct ataaaaacc aaaaagatc gcttcgtgc ccaaacgag ctagttgaa gaaatatct gacgtaaat gtaatccgc acagaatcg cacgtgacg aggttcaac agcgctcga gcacttttt gagaaacta ggcgaagag aaccgcaac aatcgcgat aaattcgca cctctccaa tgtacgaaa agcgcttcc gacatttgt gatcccaaa accaggagt aacttatct cacgaagat aactttgac tcggccaaa cacggtatt agatctcta tcgcccaac caaagaggg gcccttgaa acatgtcca gtggcaaag agcaacaat gttgtgcct agttccgag aataacgtc attatagcg aatcaaacc aagccgcta gtgaagcca gaaaaaccc gaaaaaccc cagcgaaaa ttcaacaat aaggaattg atcgagaag caaaggaat tggacttca cacttctcc aagtcacgc agtccgcgc tacagcagt gatcccaac aaaacggaa aagctagct gtgaataac ggcgattca aacacaaca catgagcac aaggtagct agcagaagt gcatctttc agtaatcga attacagga tcggtagct aacgaaaac tttcgacga aatgacgtt attcggaag gaacgtcca gcttcggtt attccgact atgtgtagt aacaataac aatgagaca agtcccaca agggtggca ccttgtgaa gatatgcac aggcgaaaa gagaggaac agtatgata ttaggggag actgaaaga ccaattgaa acatttcct gatgatgtg ccaactgta gcgcctagg gagttcgct cattcagtc actacaaac acggataat aaagaaaca aagaagcgg aaaatttgt gatcaaagt gaagaacac ttttttgtt ccttcggaa gtaaacgat aataaggac gtcagtcgg gagagttta tcagcaacg tctggcagc ttatcgtcc ctaagccct cccacaagc cccggaaag ttgaaatca gaaatcgaa aaacaagaa gatgaaggg aacgagaaa tcttttctt tcagacgtt accgactcc gcgttttgc caaacggac gatcggttg gatgtttcg gaacttgaa ccacttccc cttgaagag ggcgatcca catttgaag gcaaaagct aaatttttg tacgaaagt gcagaaact aaattaatc agcactgat aaggagcca gagattaaa ttaaccgat gccgagaaa gaggcgctt tatgctgtg ccgtgtaag aatcgcaga caagaaaaa tgtcacatt ccacccaag ccagatgtc ttgcaatcg attaaatgc gagacggat ctaaataat acggcagtg tttgcttta caagaacac cccaataac aaacggacg catatggtg tgtgataaa agtaatgaa gaggcgaaa aagaggtgt tttaaaggg gagggtgtt cctagatcg gagagccct ttgttggat tttgaaaat gagagtgaa tatgctacc attgatgat attgaagcc gattcgatg actccgact gaagaagaa catttgtta agcacaaaa atttcggaa aaacgctta gtgtcaagc agacacgac cttctctca gacgaagag gcgcaagaa gttacaaga ttgctaaat tctaaaagt ccactaacc gacgaatgg gcaacagaa tcgtcactg tttgctcta aatgagcag ccagtgcca ccgaccaat tcgtccgaa ccaacattt gtaaatcac tactcggac gtagctcct gtctcagaa aaattattt gctcactta gaagaaaaa gataaggct gatattgac gaagaagcg aacgatttc tcacaactc gactccatt gctttcata gatagctca ccgccaaac gagtcagtt gaatcccca aaacctcga agaaaatca aaagaagta gagaataag ttagatagg gaaaaaagt gactacgcc cccgagtcg gtccccatc gtgggggag gaaaacggc gtccactac tacgaagac gggcatttt tggatggag gttccaggt ctcctccca gaatccgag gaagaagac gacgaatcc gcttgttac acccatatt cccaaaccc acaaaggtc gcattttcc accgaaccc atgaaggtc tactccacg ttcagcgta acagaatac gaccgacgg aatgaagac gtcgatccc gtcgcagct tccgcagaa tacgagctt gagaaacga gtcgaaaaa atggatgtt tttccggtc gagcttatc aaaggttcg gaaggcctt ggactcagt attatcggg atgggggtt ggggcggat gcgggtttg gaaaagctg ggcatattt gtgaagact ataacagca aatggggct gccgcaaaa gacgggaga attaaagtt aatgaccag attattgaa gtcgatggg aaaagtctg gttggtgtt acgcaagct tacgctgcg agtgtttta cggaacact tccggactt gtcaaattt agtattggg cgggagagg gatccggaa aatagtgag gtggctcag cttatacga caatcgctg caggcggat agggagagg gaggagagg aggcagaag gctttagag atggagcaa cagcagagt gatgctagc acggtgcca ttaacaggt tctgcaaac actagtgta tcagacggt ccaaacagt cctttagtg agcgctgaa aattcaatg gacgtagaa cagagctca gacattgac tcgttaaaa gtgcttcta caagaatta atggagcaa aacggcata aaaccggac gactccgaa aagttggct cagttaaat caaaagctc aaggaaacg gaacgaatt ttagtaacg gcgaaaaag gagatccag acctatcag aatatgttg gaacagtct cagtcccaa tacctcgta atggaaaag aaatacact aaagcaaaa cagttactt cgagaattc caacaccgt gagttggac atgatccat cgggaggat ttctaccaa caacttttg caagaaaag gacacggaa tacaacgct ttggtgaaa aatttaaag gaccggata ataatccta gagcaggat ttgctcgaa gctcaacaa aaagctggc ttgccttgc gttctcccc aacgataat ctcaaccta aagcagctg acgccccaa atgaccaga cgcgttccc cccaagccc ttatacaac gctttagaa acgaatctg tcagacacg gaaatttcc gaccacagt ccggacgat gataagact gcaacagtt gagagaaag ctccctttg aaggaggag ctcgaccgg gttgttcct caacacgaa ctgctggac atttctgtc aataagagc aaggcggaa ttggcaaac aggggttcc ttggccaat aggcaactg ccaagtgcg aaaaaaggt tccttgagt aatagcagc agctcggat tacggctta gacgatagt tacaattca ggggacgaa gtcaattgt tgtaacgga cgtactacg aactctaat aatttatat tcgcaacat acgaggtgc caggtgcaa gctaaccca gaaacgcaa cacgatttt caatacaac aaagtacaa aaaccagtt tacgcttca tacaataaa agggtggat cccacgcca gtttacgca aaagttcaa aaggattct agtcattcg gattatacg aacccggat tcggggatt gtcaaaaag gggatcggc atgggacct ccgccttcg cttgccgaa caactgaaa caagttttg tcagagcgg gagaagcgg ttcagctct gacactctg aatagttcc tgtgaagaa ttgacggaa aggtcgaaa cacaacgcc gcccagcat ttgctcgag gagatccgg caagctgtg aacgaggca aatgcgaaa gtaaagaaa gttgtgccc gttacatta tcaccccca ggtagtact ccatggcaa catcaagga agtatgtta cctacacct ccgtctccg tcgagtttg tcgtcaggg tccgtttca ccctcaaaa cacgacgcc tcgtgggtt acaacagat ctcagtctg tcctcgtgt agtattagc agcgacaaa agagggtcg cagtattgg cagtcgacg cctatttca gaatggagc aaagaccag gtctcccag tggctgctt gggattggg atggagaac catattcca aagttcgta gagttggac gtcaatggg caagctctc ctcttgttg acgtctgcg gatttcaaa attctcggt atcgcaagt gacgataaa agctacttg aagcgaaaa ataaaagaa ctgaaaata cagaacgag aaggagcgc aaacagatg gaacggaat agaaaagag aaagagaag cttttacgg aaagcggag aaagcaaat aagaaaaag taataaata aaattagcg aatggacac ttcggccta ggaaattga agtaacatt aggtgaaat attaactat ttatcatta gtggacacc tgtgaatgg tgtattata cataattgc tgtaaatgt gactttctt gtatcagga cattacttt attatttat atgtatagc aagagtgtg agattagga atcattcat tgcaatttt ttaacgttt gtgtgataa tagtgtatg tcatgattt ttttatctt tacattttt attttatat ttttgttat attctaatt caataatta ttatcaaat aaaagtaaa aagtaact
- >TC002905 RB
cgcagattg tgcgatttc atcgaatcg tgttttgtg aagggtggt gaattttga ctgatgcaa actaatgga taatagctt attttgaca gtaatgaat aaacacaaa gctgtcgta aataaaaac atgtaaaaa ttgtgcgtc attgttcat tttctgcgg tcacctgtg catattctt gcgttaaaa ataaaagta tttatgaaa acatggcat gtataatag tgacatttg ggcgtcgtt gtaaaaaac gaatacagt gatggatta ataatcgac ttttctaat ggattaaaa tctcccctc acgatttaa acacggctg ctacctggc gccgttatg gaggacaag cggggccat cgctttggc ggctccaaa gtctcagaa atagcgaac cgattccaa gcaaaatcc tcccacagc gaggagatt atcgcccct ataaaaacc aaaaagatc gcttcgtgc ccaaacgag ctagttgaa gaaatatct gacgtaaat gtaatccgc acagaatcg cacgtgacg aggttcaac agcgctcga gcacttttt gagaaacta ggcgaagag aaccgcaac aatcgcgat aaattcgca cctctccaa tgtacgaaa agcgcttcc gacatttgt gatcccaaa accaggagt aacttatct cacgaagat aactttgac tcggccaaa cacggtatt agatctcta tcgcccaac caaagaggg gcccttgaa acatgtcca gtggcaaag agcaacaat gttgtgcct agttccgag aataacgtc attatagcg aatcaaacc aagccgcta gtgaagcca gaaaaaccc gaaaaaccc cagcgaaaa ttcaacaat aaggaattg atcgagaag caaaggaat tggacttca cacttctcc aagtcacgc agtccgcgc tacagcagt gatcccaac aaaacggaa aagctagct gtgaataac ggcgattca aacacaaca catgagcac aaggtagct agcagaagt gcatctttc agtaatcga attacagga tcggtagct aacgaaaac tttcgacga aatgacgtt attcggaag gaacgtcca gcttcggtt attccgact atgtgtagt aacaataac aatgagaca agtcccaca agggtggca ccttgtgaa gatatgcac aggcgaaaa gagaggaac agtatgata ttaggggag actgaaaga ccaattgaa acatttcct gatgatgtg ccaactgta gcgcctagg gagttcgct cattcagtc actacaaac acggataat aaagaaaca aagaagcgg aaaatttgt gatcaaagt gaagaacac ttttttgtt ccttcggaa gtaaacgat aataaggac gtcagtcgg gagagttta tcagcaacg tctggcagc ttatcgtcc ctaagccct cccacaagc cccggaaag ttgaaatca gaaatcgaa aaacaagaa gatgaaggg aacgagaaa tcttttctt tcagacgtt accgactcc gcgttttgc caaacggac gatcggttg gatgtttcg gaacttgaa ccacttccc cttgaagag ggcgatcca catttgaag gcaaaagct aaatttttg tacgaaagt gcagaaact aaattaatc agcactgat aaggagcca gagattaaa ttaaccgat gccgagaaa gaggcgctt tatgctgtg ccgtgtaag aatcgcaga caagaaaaa tgtcacatt ccacccaag ccagatgtc ttgcaatcg attaaatgc gagacggat ctaaataat acggcagtg tttgcttta caagaacac cccaataac aaacggacg catatggtg tgtgataaa agtaatgaa gaggcgaaa aagaggtgt tttaaaggg gagggtgtt cctagatcg gagagccct ttgttggat tttgaaaat gagagtgaa tatgctacc attgatgat attgaagcc gattcgatg actccgact gaagaagaa catttgtta agcacaaaa atttcggaa aaacgctta gtgtcaagc agacacgac cttctctca gacgaagag gcgcaagaa gttacaaga ttgctaaat tctaaaagt ccactaacc gacgaatgg gcaacagaa tcgtcactg tttgctcta aatgagcag ccagtgcca ccgaccaat tcgtccgaa ccaacattt gtaaatcac tactcggac gtagctcct gtctcagaa aaattattt gctcactta gaagaaaaa gataaggct gatattgac gaagaagcg aacgatttc tcacaactc gactccatt gctttcata gatagctca ccgccaaac gagtcagtt gaatcccca aaacctcga agaaaatca aaagaagag aataagtta gatagggaa aaaagtgac tacgccccc gagtcggtc cccatcgtg ggggaggaa aacggcgtc cactactac gaagacggg catttttgg atggaggtt ccaggtctc ctcccagaa tccgaggaa gaagacgac gaatccgct tgttacacc catattccc aaacccaca aaggtcgca ttttccacc gaacccatg aaggtctac tccacgttc agcgtaaca gaatacgac cgacggaat gaagacgtc gatcccgtc gcagcttcc gcagaatac gagcttgag aaacgagtc gaaaaaatg gatgttttt ccggtcgag cttatcaaa ggttcggaa ggccttgga ctcagtatt atcgggatg ggggttggg gcggatgcg ggtttggaa aagctgggc atatttgtg aagactata acagcaaat ggggctgcc gcaaaagac gggagaatt aaagttaat gaccagatt attgaagtc gatgggaaa agtctggtt ggtgttacg caagcttac gctgcgagt gttttacgg aacacttcc ggacttgtc aaatttagt attgggcgg gagagggat ccggaaaat agtgaggtg gctcagctt atacgacaa tcgctgcag gcggatagg gagagggag gagaggagg cagaaggct ttagagatg gagcaacag cagagtgat gctagcacg gtgccatta acaggttct gcaaacact agtgtatca gacggtcca aacagtcct ttagtgagc gctgaaaat tcaatggac gtagaacag agctcagac attgactcg ttaaaagtg cttctacaa gaattaatg gagcaaaac ggcataaaa ccggacgac tccgaaaag ttggctcag ttaaatcaa aagctcaag gaaacggaa cgaatttta gtaacggcg aaaaaggag atccagacc tatcagaat atgttggaa cagtctcag tcccaatac ctcgtaatg gaaaagaaa tacactaaa gcaaaacag ttacttcga gaattccaa caccgtgag ttggacatg atccatcgg gaggatttc taccaacaa cttttgcaa gaaaaggac acggaatac aacgctttg gtgaaaaat ttaaaggac cggataata atcctagag caggatttg ctcgaagct caacaaaaa gctggcttg ccttgcgtt ctccccaac gataatctc aacctaaag cagctgacg ccccaaatg accagacgc gttcccccc aagccctta tacaacgct ttagaaacg aatctgtca gacacggaa atttccgac cacagtccg gacgatgat aagactgca acagttgag agaaagctc cctttgaag gaggagctc gaccgggtt gttcctcaa cacgaactg ctggacatt tctgtcaat aagagcaag gcggaattg gcaaacagg ggttccttg gccaatagg caactgcca agtgcgaaa aaaggttcc ttgagtaat agcagcagc tcggattac ggcttagac gatagttac aattcaggg gacgaagtc aattgttgt aacggacgt actacgaac tctaataat ttatattcg caacatacg aggtgccag gtgcaagct aacccagaa acgcaacac gattttcaa tacaacaaa gtacaaaaa ccagtttac gcttcatac aataaaagg gtggatccc acgccagtt tacgcaaaa gttcaaaag gattctagt cattcggat tatacgaac ccggattcg gggattgtc aaaaagggg atcggcatg ggacctccg ccttcgctt gccgaacaa ctgaaacaa gttttgtca gagcgggag aagcggttc agctctgac actctgaat agttcctgt gaagaattg acggaaagg tcgaaacac aacgccgcc cagcatttg ctcgaggag atccggcaa gctgtgaac gaggcaaat gcgaaagta aagaaagtt gtgcccgtt acattatca cccccaggt agtactcca tggcaacat caaggaagt atgttacct acacctccg tctccgtcg agtttgtcg tcagggtcc gtttcaccc tcaaaacac gacgcctcg tgggttaca acagatctc agtctgtcc tcgtgtagt attagcagc gacaaaaga gggtcgcag tattggcag tcgacgcct atttcagaa tggagcaaa gaccaggtc tcccagtgg ctgcttggg attgggatg gagaaccat attccaaag ttcgtagag ttggacgtc aatgggcaa gctctcctc ttgttgacg tctgcggat ttcaaaatt ctcggtatc gcaagtgac gataaaagc tacttgaag cgaaaaata aaagaactg aaaatacag aacgagaag gagcgcaaa cagatggaa cggaataga aaagagaaa gagaagctt ttacggaaa gcggagaaa gcaaataag aaaaagtaa taaataaaa ttagcgaat ggacacttc ggcctagga aattgaagt aacattagg tgaaatatt aactattta tcattagtg gacacctgt gaatggtgt attatacat aattgctgt aaatgtgac tttcttgta tcaggacat tactttatt atttatatg tatagcaag agtgtgaga ttaggaatc attcattgc aatttttta acgtttgtg tgataatag tgtatgtca tgatttttt tatctttac atttttatt ttatatttt tgttatatt ctaattcaa taattatta tcaaataaa agtaaaaag taact
- >TC002905 RC
cgcagattg tgcgatttc atcgaatcg tgttttgtg aagggtggt gaattttga ctgatgcaa actaatgga taatagctt attttgaca gtaatgaat aaacacaaa gctgtcgta aataaaaac atgtaaaaa ttgtgcgtc attgttcat tttctgcgg tcacctgtg catattctt gcgttaaaa ataaaagta tttatgaaa acatggcat gtataatag tgacatttg ggcgtcgtt gtaaaaaac gaatacagt gatggatta ataatcgac ttttctaat ggattaaaa tctcccctc acgatttaa acacggctg ctacctggc gccgttatg gaggacaag cggggccat cgctttggc ggctccaaa gtctcagaa atagcgaac cgattccaa gcaaaatcc tcccacagc gaggagatt atcgcccct ataaaaacc aaaaagatc gcttcgtgc ccaaacgag ctagttgaa gaaatatct gacgtaaat gtaatccgc acagaatcg cacgtgacg aggttcaac agcgctcga gcacttttt gagaaacta ggcgaagag aaccgcaac aatcgcgat aaattcgca cctctccaa tgtacgaaa agcgcttcc gacatttgt gatcccaaa accaggagt aacttatct cacgaagat aactttgac tcggccaaa cacggtatt agatctcta tcgcccaac caaagaggg gcccttgaa acatgtcca gtggcaaag agcaacaat gttgtgcct agttccgag aataacgtc attatagcg aatcaaacc aagccgcta gtgaagcca gaaaaaccc gaaaaaccc cagcgaaaa ttcaacaat aaggaattg atcgagaag caaaggaat tggacttca cacttctcc aagtcacgc agtccgcgc tacagcagt gatcccaac aaaacggaa aagctagct gtgaataac ggcgattca aacacaaca catgagcac aaggtagct agcagaagt gcatctttc agtaatcga attacagga tcggtagct aacgaaaac tttcgacga aatgacgtt attcggaag gaacgtcca gcttcggtt attccgact atgtgtagt aacaataac aatgagaca agtcccaca agggtggca ccttgtgaa gatatgcac aggcgaaaa gagaggaac agtatgata ttaggggag actgaaaga ccaattgaa acatttcct gatgatgtg ccaactgta gcgcctagg gagttcgct cattcagtc actacaaac acggataat aaagaaaca aagaagcgg aaaatttgt gatcaaagt gaagaacac ttttttgtt ccttcggaa gtaaacgat aataaggac gtcagtcgg gagagttta tcagcaacg tctggcagc ttatcgtcc ctaagccct cccacaagc cccggaaag ttgaaatca gaaatcgaa aaacaagaa gatgaaggg aacgagaaa tcttttctt tcagacgtt accgactcc gcgttttgc caaacggac gatcggttg gatgtttcg gaacttgaa ccacttccc cttgaagag ggcgatcca catttgaag gcaaaagct aaatttttg tacgaaagt gcagaaact aaattaatc agcactgat aaggagcca gagattaaa ttaaccgat gccgagaaa gaggcgctt tatgctgtg ccgtgtaag aatcgcaga caagaaaaa tgtcacatt ccacccaag ccagatgtc ttgcaatcg attaaatgc gagacggat ctaaataat acggcagtg tttgcttta caagaacac cccaataac aaacggacg catatggtg tgtgataaa agtaatgaa gaggcgaaa aagaggtgt tttaaaggg gagggtgtt cctagatcg gagagccct ttgttggat tttgaaaat gagagtgaa tatgctacc attgatgat attgaagcc gattcgatg actccgact gaagaagaa catttgtta agcacaaaa atttcggaa aaacgctta gtgtcaagc agacacgac cttctctca gacgaagag gcgcaagaa gttacaaga ttgctaaat tctaaaagt ccactaacc gacgaatgg gcaacagaa tcgtcactg tttgctcta aatgagcag ccagtgcca ccgaccaat tcgtccgaa ccaacattt gtaaatcac tactcggac gtagctcct gtctcagaa aaattattt gctcactta gaagaaaaa gataaggct gatattgac gaagaagcg aacgatttc tcacaactc gactccatt gctttcata gatagctca ccgccaaac gagtcagtt gaatcccca aaacctcga agaaaatca aaagaagta gagaataag ttagatagg gaaaaaagt gactacgcc cccgagtcg gtccccatc gtgggggag gaaaacggc gtccactac tacgaagac gggcatttt tggatggag gttccaggt ctcctccca gaatccgag gaagaagac gacgaatcc gcttgttac acccatatt cccaaaccc acaaaggtc gcattttcc accgaaccc atgaaggtc tactccacg ttcagcgta acagaatac gaccgacgg aatgaagac gtcgatccc gtcgcagct tccgcagaa tacgagctt gagaaacga gtcgaaaaa atggatgtt tttccggtc gagcttatc aaaggttcg gaaggcctt ggactcagt attatcggg atgggggtt ggggcggat gcgggtttg gaaaagctg ggcatattt gtgaagact ataacagca aatggggct gccgcaaaa gacgggaga attaaagtt aatgaccag attattgaa gtcgatggg aaaagtctg gttggtgtt acgcaagct tacgctgcg agtgtttta cggaacact tccggactt gtcaaattt agtattggg cgggagagg gatccggaa aatagtgag gtggctcag cttatacga caatcgctg caggcggat agggagagg gaggagagg aggcagaag gctttagag atggagcaa cagcagagt gatgctagc acggtgcca ttaacaggt tctgcaaac actagtgta tcagacggt ccaaacagt cctttagtg agcgctgaa aattcaatg gacgtagaa cagagctca gacattgac tcgttaaaa gtgcttcta caagaatta atggagcaa aacggcata aaaccggac gactccgaa aagttggct cagttaaat caaaagctc aaggaaacg gaacgaatt ttagtaacg gcgaaaaag gagatccag acctatcag aatatgttg gaacagtct cagtcccaa tacctcgta atggaaaag aaatacact aaagcaaaa cagttactt cgagaattc caacaccgt gagttggac atgatccat cgggaggat ttctaccaa caacttttg caagaaaag gacacggaa tacaacgct ttggtgaaa aatttaaag gaccggata ataatccta gagcaggat ttgctcgaa gctcaacaa aaagctggc ttgccttgc gttctcccc aacgataat ctcaaccta aagcagctg acgccccaa atgaccaga cgcgttccc cccaagccc ttatacaac gctttagaa acgaatctg tcagacacg gaaatttcc gaccacagt ccggacgat gataagact gcaacagtt gagagaaag ctccctttg aaggaggag ctcgaccgg gttgttcct caacacgaa ctgctggac atttctgtc aataagagc aaggcggaa ttggcaaac aggggttcc ttggccaat aggcaactg ccaagtgcg aaaaaaggt tccttgagt aatagcagc agctcggat tacggctta gacgatagt tacaattca ggggacgaa gtcaattgt tgtaacgga cgtactacg aactctaat aatttatat tcgcaacat acgaggtgc caggtgcaa gctaaccca gaaacgcaa cacgatttt caatacaac aaagtacaa aaaccagtt tacgcttca tacaataaa agggtggat cccacgcca gtttacgca aaagttcaa aaggattct agtcattcg gattatacg aacccggat tcggggatt gtcaaaaag gggatcggc atgggacct ccgccttcg cttgccgaa caactgaaa caagttttg tcagagcgg gagaagcgg ttcagctct gacactctg aatagttcc tgtgaagaa ttgacggaa aggtcgaaa cacaacgcc gcccagcat ttgctcgag gagatccgg caagctgtg aacgaggca aatgcgaaa ggtagtact ccatggcaa catcaagga agtatgtta cctacacct ccgtctccg tcgagtttg tcgtcaggg tccgtttca ccctcaaaa cacgacgcc tcgtgggtt acaacagat ctcagtctg tcctcgtgt agtattagc agcgacaaa agagggtcg cagtattgg cagtcgacg cctatttca gaatggagc aaagaccag gtctcccag tggctgctt gggattggg atggagaac catattcca aagttcgta gagttggac gtcaatggg caagctctc ctcttgttg acgtctgcg gatttcaaa attctcggt atcgcaagt gacgataaa agctacttg aagcgaaaa ataaaagaa ctgaaaata cagaacgag aaggagcgc aaacagatg gaacggaat agaaaagag aaagagaag cttttacgg aaagcggag aaagcaaat aagaaaaag taataaata aaattagcg aatggacac ttcggccta ggaaattga agtaacatt aggtgaaat attaactat ttatcatta gtggacacc tgtgaatgg tgtattata cataattgc tgtaaatgt gactttctt gtatcagga cattacttt attatttat atgtatagc aagagtgtg agattagga atcattcat tgcaatttt ttaacgttt gtgtgataa tagtgtatg tcatgattt ttttatctt tacattttt attttatat ttttgttat attctaatt caataatta ttatcaaat aaaagtaaa aagtaact
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