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Gene information
General information
TC012455 Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007424.3: 7756236..7778628
Sequence information
Transcripts / Proteins (2) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    TC012455
    iBeetle screen iB_02921

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 100.0% (includes death as pupa, adult)

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 2 (3 dpi)
    Days post injection


    adult lethality - Number of animals showing the phenotype: 8 (9 dpi)
    Days post injection


    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 80.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 100.0% (includes death as larva, prepupa, pupa, adult)

    larva lethality early (L5/6) - Number of animals showing the phenotype: 7 (11 dpi)
    Days post injection


    pupal molt delayed (still larva) - Number of animals showing the phenotype: 2 (11 dpi)
    Days post injection


    larva lethality late (L7) - Number of animals showing the phenotype: 2 (16 dpi)
    Days post injection


    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC012455 RA
      MSEQLKVGQ KVKVTGKDV QGVIAFIGP TSFAADTWI 
      GLKLDEPKG KNNGSVQGV EYFKCEDKH GLFVKPSQV 
      IPLDEHGKP LRDAGEETP KARARPSSS RLSLASSRQ 
      SLADSRQSL SGSRQSLAG SRQSLMGSR SHLASPIVE 
      KSDAGDHPS QIPKRASFI ETGFVETLN PQFTPGQVI 
      TTTPTPITS VDEKINVIQ LQQEIENRN QQIRDLGEK 
      LETLKIKRQ EDKEKLKEL DKLKIQLEQ LVEFKTKIM 
      EVQASLQRE VQRAKQEAK EAVEAKEAH AEEVADLAE 
      AVEMATLDK EMAEEKAET LQLELEVCK EKLEEVTLD 
      LKILKTEMQ EPGGTSASG EEAVSTYEV KQLQQQNAR 
      LRETLVRLR DLSAHDKHE YQKLLKDID QKKSEIVEL 
      GKTKEKLSA RVEEMEQQV ADLQEQVDA AMGAEEMVV 
      ILGEQKLTL EEKVAQLLE EVAELEALQ DMNDQLVES 
      NAELEAELR EDLDMARMA AKQAMRDRD AALETIADR 
      EATLNKFRE LVQKLQEQS LQLQSRLET ESSKPVSAL 
      PEIVDFTKM FNETKAHTK AIDLELRRV EIQQLQSHI 
      KFLTSYMPD SFMNRGGDY DAVLVLLLV LRMIQKTEI 
      LIGQIKDKF PGVDKIDRA AILKGHAVE QFSFRCRAS 
      FYIYALQSI LHQYYYALN TCKTEALLK VGATYPEMA 
      SYEKIIDGF IELVKRDQL DENVPTEAL EKCVGYFNT 
      LFPVLLGPE NRLNHTQLL VDNVKSLTS ACDGFNNDS 
      IVIRNLIET ANVGDIGLL AQHVITTSE QLQQQLKLI 
      KRRLPPDSN VANIGLNKE VFENLYQCY QHCGRIIKT 
      LQDIVKNSV QLMTSSGEL EKGLPQDKI KEIALNASD 
      KIYEQDDLG PVQSIKNSL SFVVTQTTQ IAQFLQDNE 
      YEIATANKN EEKPIPPIQ IRADAVKKE LEQTKTLTS 
      KLENKESDI KELRKALKE KQEQLSEMT IRKELAEKK 
      LGNVNKDYE LTIEKLQRK LEEAHNNYK KKEKEFEET 
      LDHLQTDID SLENEKGEM KEKLKLLSK KTQMELSTS 
      RSASGSQLS AQQSLGPSL PAVVKDSPL LLQEIESLR 
      KLFHQERNE RIKLENEKI KKELDSLAP LPSFKTTPD 
      EVLDKLFKE GALLKQEIL MSLAKPKFP QIYKVKPGN 
      GPAAWKKHF AEENDKLAD LNRRAREFQ TKVANEIIK 
      RKMGGRVEA DFAVFPTIE MVKALSESK PVNIGYVKI 
      PKSYLPKGE KPRIVDLEL DFINLQKIL QSLSC
    • >TC012455 RB
      MSEQLKVGQ KVKVTGKDV QGVIAFIGP TSFAADTWI 
      GLKLDEPKG KNNGSVQGV EYFKCEDKH GLFVKPSQV 
      IPLDEHGKP LRDAGEETP KARARPSSV GTKPKPTTS 
      RLSLASSRQ SLADSRQSL SGSRQSLAG SRQSLMGSR 
      SHLASPIVE KSDAGDHPS QIPKRASFI ETGFVETLN 
      PQFTPGQVI TTTPTPITS VDEKINVIQ LQQEIENRN 
      QQIRDLGEK LETLKIKRQ EDKEKLKEL DKLKIQLEQ 
      LVEFKTKIM EVQASLQRE VQRAKQEAK EAVEAKEAH 
      AEEVADLAE AVEMATLDK EMAEEKAET LQLELEVCK 
      EKLEEVTLD LKILKTEMQ EPGGTSASG EEAVSTYEV 
      KQLQQQNAR LRETLVRLR DLSAHDKHE YQKLLKDID 
      QKKSEIVEL GKTKEKLSA RVEEMEQQV ADLQEQVDA 
      AMGAEEMVV ILGEQKLTL EEKVAQLLE EVAELEALQ 
      DMNDQLVES NAELEAELR EDLDMARMA AKQAMRDRD 
      AALETIADR EATLNKFRE LVQKLQEQS LQLQSRLET 
      ESSKPVSAL PEIVDFTKM FNETKAHTK AIDLELRRV 
      EIQQLQSHI KFLTSYMPD SFMNRGGDY DAVLVLLLV 
      LRMIQKTEI LIGQIKDKF PGVDKIDRA AILKGHAVE 
      QFSFRCRAS FYIYALQSI LHQYYYALN TCKTEALLK 
      VGATYPEMA SYEKIIDGF IELVKRDQL DENVPTEAL 
      EKCVGYFNT LFPVLLGPE NRLNHTQLL VDNVKSLTS 
      ACDGFNNDS IVIRNLIET ANVGDIGLL AQHVITTSE 
      QLQQQLKLI KRRLPPDSN VANIGLNKE VFENLYQCY 
      QHCGRIIKT LQDIVKNSV QLMTSSGEL EKGLPQDKI 
      KEIALNASD KIYEQDDLG PVQSIKNSL SFVVTQTTQ 
      IAQFLQDNE YEIATANKN EEKPIPPIQ IRADAVKKE 
      LEQTKTLTS KLENKESDI KELRKALKE KQEQLSEMT 
      IRKELAEKK LGNVNKDYE LTIEKLQRK LEEAHNNYK 
      KKEKEFEET LDHLQTDID SLENEKGEM KEKLKLLSK 
      KTQMELSTS RSASGSQLS AQQSLGPSL PAVVKDSPL 
      LLQEIESLR KLFHQERNE RIKLENEKI KKELDSLAP 
      LPSFKTTPD EVLDKLFKE GALLKQEIL MSLAKPKFP 
      QIYKVKPGN GPAAWKKHF AEENDKLAD LNRRAREFQ 
      TKVANEIIK RKMGGRVEA DFAVFPTIE MVKALSESK 
      PVNIGYVKI PKSYLPKGE KPRIVDLEL DFINLQKIL 
      QSLSC
    CDS sequence
    • >TC012455 RA
      atgtcggag caactgaaa gtcggtcag aaagtcaaa 
      gtgaccggt aaagacgtc cagggggtt attgcgttc 
      atcggcccc acgagcttt gcggccgac acatggatc 
      ggtctcaag ctggacgag cccaagggt aagaacaac 
      gggagtgtt cagggggtt gaatacttc aagtgcgag 
      gacaagcac gggctgttt gtgaagccg tcgcaggtg 
      atccccctc gacgagcat ggcaagccg ctccgggac 
      gccggagag gagaccccc aaggctcgg gccaggcct 
      agcagttct cgcttgtca ctggccagt agccggcag 
      tctttggcc gatagccgc cagtcactg tccggcagc 
      cgccaatcg cttgcagga agtcgccaa tcccttatg 
      gggagtcgt agtcacttg gcctcaccg attgttgaa 
      aagtcagat gcgggggat cacccgagc caaatcccc 
      aaacgggcc tcatttatt gagaccggc tttgtggaa 
      accctcaat ccacaattc acaccaggc caagtgatc 
      acgaccaca ccgactcca attacctcc gttgacgag 
      aagattaac gtaatccag ctgcaacaa gagatcgaa 
      aatcgcaac caacaaata cgcgatctg ggcgagaag 
      ttggaaact ttgaaaatt aagcgccag gaggacaag 
      gagaagttg aaggagttg gataaattg aaaatccag 
      ttggagcaa ttggttgaa ttcaagacg aaaattatg 
      gaagtgcag gcgagtttg cagagggag gtgcaaagg 
      gccaagcag gaggcgaaa gaagcggtc gaggccaag 
      gaggcgcac gctgaggaa gtggccgac ttggccgaa 
      gccgtcgaa atggccacc cttgacaag gaaatggcg 
      gaggaaaag gcagaaacc ttgcagctg gaattggaa 
      gtgtgcaaa gagaagttg gaagaggtg acgctcgac 
      ctgaaaatt ctcaaaacg gagatgcaa gaacctggt 
      ggaacttca gcaagtggg gaagaagcc gtttccacc 
      tacgaagtg aaacaactc cagcagcaa aatgcccga 
      cttcgggaa actctagtc aggttgagg gatctctca 
      gctcacgac aaacacgaa tatcagaaa cttctaaaa 
      gacatcgac cagaagaaa tccgaaatt gtcgagttg 
      gggaaaacg aaggaaaag ttgagtgcc agggttgaa 
      gaaatggag caacaagtt gccgatctt caagaacag 
      gtcgatgcg gcgatgggc gccgaagaa atggtcgta 
      atcctcggc gagcagaag ctcaccctg gaggagaaa 
      gtggcccaa ctcctcgaa gaagtcgcc gaactggaa 
      gccctccaa gacatgaac gaccaactg gtcgaaagc 
      aacgccgag ctggaagcc gaactgcgc gaagacctc 
      gacatggcc cgaatggcc gccaaacag gcgatgcgc 
      gaccgcgac gccgccttg gaaacaata gccgaccgc 
      gaagccact ctcaacaaa ttccgcgaa ctcgtccaa 
      aaactccaa gagcagtcg ctgcagctg caaagtcgg 
      ctcgaaacc gagtcgagc aaacccgtc tcagctctg 
      cccgaaatc gtcgacttc acgaaaatg ttcaacgag 
      acgaaggcc cacaccaaa gctatcgac ttggagctg 
      agacgcgtt gaaatccaa cagctgcaa agccacatc 
      aagttcttg acctcttac atgccggat tcgttcatg 
      aaccgcggc ggggattac gacgctgtg ctggtgctg 
      ctgctggtc ttgcggatg attcagaag acggagatt 
      ctgatcggg cagatcaag gacaagttt ccgggggtt 
      gataagatt gatagggcg gcgattttg aaagggcat 
      gctgtggag cagttctcg ttcaggtgc agggcttcg 
      ttctatatt tatgcccta cagtcgatt ttgcaccag 
      tattactat gcgttaaat acgtgtaaa acagaggca 
      cttctcaaa gtcggagct acgtatcct gagatggct 
      tcctacgag aaaatcatt gatgggttc attgaattg 
      gtgaaacgc gatcaactg gacgagaat gtaccgact 
      gaagcactc gaaaaatgt gttggatat ttcaataca 
      ctgtttcct gtgcttcta ggaccggaa aatcgcctc 
      aatcacacg caattgttg gtcgacaat gttaaaagt 
      ttaacgtcg gcgtgtgac ggctttaat aacgattct 
      atcgtcatc agaaacttg attgagact gccaatgtt 
      ggtgacatc ggattgtta gcccaacac gtcataaca 
      acatctgaa cagttgcaa caacaacta aaactgata 
      aaacggcgc cttccgccc gactcgaac gttgccaac 
      atcggttta aacaaggaa gtttttgag aacttgtac 
      cagtgttac caacactgc ggccgcatc ataaaaaca 
      ttgcaagac atcgtcaag aactcagtc cagttgatg 
      acatctagc ggagaactg gaaaaagga ctcccacag 
      gacaaaatc aaagaaatc gcgttgaat gccagcgat 
      aagatctac gaacaggac gacttaggt ccagtgcaa 
      agtattaaa aattcgctg agtttcgta gtcactcag 
      acgacgcaa attgcgcag tttttgcaa gataacgag 
      tacgaaatt gcgacggct aataaaaac gaggagaag 
      cccatacct ccgatccaa attcgggcc gatgctgtg 
      aaaaaagag ctcgaacaa acgaaaact ttgacgagc 
      aaattggag aacaaagag tccgatatt aaagagttg 
      cgtaaagca ctcaaagag aaacaagag caattatcc 
      gaaatgacc atacggaag gaattagct gagaaaaag 
      ttgggtaac gtcaataaa gattacgag ttgacgatt 
      gaaaagctg caaaggaag ctggaagag gcgcacaat 
      aactacaaa aagaaggag aaggagttc gaggagact 
      ttagaccat ctccagacc gatatcgat tcgctcgag 
      aatgaaaaa ggcgaaatg aaggagaag ttaaaactg 
      ctctcgaag aaaacacaa atggagttg tcaacttca 
      agaagcgcg tccggttcc caattatcc gcccaacaa 
      tctctaggt ccaagtctc ccagctgtg gtcaaagac 
      tcgcccttg ctcctgcaa gaaattgag agtctccgg 
      aagctgttt caccaagaa cgcaacgag agaatcaaa 
      ctcgaaaat gagaaaatc aaaaaggag ttggacagt 
      ttggctccc ttgccctcg ttcaagacc acaccggac 
      gaagttctg gataaatta ttcaaagag ggggcgtta 
      cttaaacag gaaattttg atgagtttg gctaaaccg 
      aagttcccg caaatttac aaagtcaag ccggggaat 
      gggccagct gcttggaag aaacatttc gctgaggaa 
      aacgacaag ttggcggat ctcaacagg cgagcgcgc 
      gagttccag acgaaggta gccaatgag attatcaag 
      cggaagatg ggggggagg gtagaagcg gatttcgca 
      gtttttccc acgattgag atggttaag gcattgagt 
      gagagtaag ccggtgaat atcggctac gtgaaaatc 
      ccgaagagc tacttgccg aagggggag aagcctcgg 
      atcgttgac ttggagttg gactttatc aacttgcag 
      aagatcctg cagtcgcta tcgtgttaa
    • >TC012455 RB
      atgtcggag caactgaaa gtcggtcag aaagtcaaa 
      gtgaccggt aaagacgtc cagggggtt attgcgttc 
      atcggcccc acgagcttt gcggccgac acatggatc 
      ggtctcaag ctggacgag cccaagggt aagaacaac 
      gggagtgtt cagggggtt gaatacttc aagtgcgag 
      gacaagcac gggctgttt gtgaagccg tcgcaggtg 
      atccccctc gacgagcat ggcaagccg ctccgggac 
      gccggagag gagaccccc aaggctcgg gccaggcct 
      agcagcgtc ggtacaaaa cccaaacct acaacttct 
      cgcttgtca ctggccagt agccggcag tctttggcc 
      gatagccgc cagtcactg tccggcagc cgccaatcg 
      cttgcagga agtcgccaa tcccttatg gggagtcgt 
      agtcacttg gcctcaccg attgttgaa aagtcagat 
      gcgggggat cacccgagc caaatcccc aaacgggcc 
      tcatttatt gagaccggc tttgtggaa accctcaat 
      ccacaattc acaccaggc caagtgatc acgaccaca 
      ccgactcca attacctcc gttgacgag aagattaac 
      gtaatccag ctgcaacaa gagatcgaa aatcgcaac 
      caacaaata cgcgatctg ggcgagaag ttggaaact 
      ttgaaaatt aagcgccag gaggacaag gagaagttg 
      aaggagttg gataaattg aaaatccag ttggagcaa 
      ttggttgaa ttcaagacg aaaattatg gaagtgcag 
      gcgagtttg cagagggag gtgcaaagg gccaagcag 
      gaggcgaaa gaagcggtc gaggccaag gaggcgcac 
      gctgaggaa gtggccgac ttggccgaa gccgtcgaa 
      atggccacc cttgacaag gaaatggcg gaggaaaag 
      gcagaaacc ttgcagctg gaattggaa gtgtgcaaa 
      gagaagttg gaagaggtg acgctcgac ctgaaaatt 
      ctcaaaacg gagatgcaa gaacctggt ggaacttca 
      gcaagtggg gaagaagcc gtttccacc tacgaagtg 
      aaacaactc cagcagcaa aatgcccga cttcgggaa 
      actctagtc aggttgagg gatctctca gctcacgac 
      aaacacgaa tatcagaaa cttctaaaa gacatcgac 
      cagaagaaa tccgaaatt gtcgagttg gggaaaacg 
      aaggaaaag ttgagtgcc agggttgaa gaaatggag 
      caacaagtt gccgatctt caagaacag gtcgatgcg 
      gcgatgggc gccgaagaa atggtcgta atcctcggc 
      gagcagaag ctcaccctg gaggagaaa gtggcccaa 
      ctcctcgaa gaagtcgcc gaactggaa gccctccaa 
      gacatgaac gaccaactg gtcgaaagc aacgccgag 
      ctggaagcc gaactgcgc gaagacctc gacatggcc 
      cgaatggcc gccaaacag gcgatgcgc gaccgcgac 
      gccgccttg gaaacaata gccgaccgc gaagccact 
      ctcaacaaa ttccgcgaa ctcgtccaa aaactccaa 
      gagcagtcg ctgcagctg caaagtcgg ctcgaaacc 
      gagtcgagc aaacccgtc tcagctctg cccgaaatc 
      gtcgacttc acgaaaatg ttcaacgag acgaaggcc 
      cacaccaaa gctatcgac ttggagctg agacgcgtt 
      gaaatccaa cagctgcaa agccacatc aagttcttg 
      acctcttac atgccggat tcgttcatg aaccgcggc 
      ggggattac gacgctgtg ctggtgctg ctgctggtc 
      ttgcggatg attcagaag acggagatt ctgatcggg 
      cagatcaag gacaagttt ccgggggtt gataagatt 
      gatagggcg gcgattttg aaagggcat gctgtggag 
      cagttctcg ttcaggtgc agggcttcg ttctatatt 
      tatgcccta cagtcgatt ttgcaccag tattactat 
      gcgttaaat acgtgtaaa acagaggca cttctcaaa 
      gtcggagct acgtatcct gagatggct tcctacgag 
      aaaatcatt gatgggttc attgaattg gtgaaacgc 
      gatcaactg gacgagaat gtaccgact gaagcactc 
      gaaaaatgt gttggatat ttcaataca ctgtttcct 
      gtgcttcta ggaccggaa aatcgcctc aatcacacg 
      caattgttg gtcgacaat gttaaaagt ttaacgtcg 
      gcgtgtgac ggctttaat aacgattct atcgtcatc 
      agaaacttg attgagact gccaatgtt ggtgacatc 
      ggattgtta gcccaacac gtcataaca acatctgaa 
      cagttgcaa caacaacta aaactgata aaacggcgc 
      cttccgccc gactcgaac gttgccaac atcggttta 
      aacaaggaa gtttttgag aacttgtac cagtgttac 
      caacactgc ggccgcatc ataaaaaca ttgcaagac 
      atcgtcaag aactcagtc cagttgatg acatctagc 
      ggagaactg gaaaaagga ctcccacag gacaaaatc 
      aaagaaatc gcgttgaat gccagcgat aagatctac 
      gaacaggac gacttaggt ccagtgcaa agtattaaa 
      aattcgctg agtttcgta gtcactcag acgacgcaa 
      attgcgcag tttttgcaa gataacgag tacgaaatt 
      gcgacggct aataaaaac gaggagaag cccatacct 
      ccgatccaa attcgggcc gatgctgtg aaaaaagag 
      ctcgaacaa acgaaaact ttgacgagc aaattggag 
      aacaaagag tccgatatt aaagagttg cgtaaagca 
      ctcaaagag aaacaagag caattatcc gaaatgacc 
      atacggaag gaattagct gagaaaaag ttgggtaac 
      gtcaataaa gattacgag ttgacgatt gaaaagctg 
      caaaggaag ctggaagag gcgcacaat aactacaaa 
      aagaaggag aaggagttc gaggagact ttagaccat 
      ctccagacc gatatcgat tcgctcgag aatgaaaaa 
      ggcgaaatg aaggagaag ttaaaactg ctctcgaag 
      aaaacacaa atggagttg tcaacttca agaagcgcg 
      tccggttcc caattatcc gcccaacaa tctctaggt 
      ccaagtctc ccagctgtg gtcaaagac tcgcccttg 
      ctcctgcaa gaaattgag agtctccgg aagctgttt 
      caccaagaa cgcaacgag agaatcaaa ctcgaaaat 
      gagaaaatc aaaaaggag ttggacagt ttggctccc 
      ttgccctcg ttcaagacc acaccggac gaagttctg 
      gataaatta ttcaaagag ggggcgtta cttaaacag 
      gaaattttg atgagtttg gctaaaccg aagttcccg 
      caaatttac aaagtcaag ccggggaat gggccagct 
      gcttggaag aaacatttc gctgaggaa aacgacaag 
      ttggcggat ctcaacagg cgagcgcgc gagttccag 
      acgaaggta gccaatgag attatcaag cggaagatg 
      ggggggagg gtagaagcg gatttcgca gtttttccc 
      acgattgag atggttaag gcattgagt gagagtaag 
      ccggtgaat atcggctac gtgaaaatc ccgaagagc 
      tacttgccg aagggggag aagcctcgg atcgttgac 
      ttggagttg gactttatc aacttgcag aagatcctg 
      cagtcgcta tcgtgttaa
    mRNA sequence
    • >TC012455 RA
      tcaaaagag tgccaagtt cctggttgt cttgtattt 
      tcctcgctt tatttaata attttactg gcataaaat 
      aacataaac cctttattg gaatagtaa ataatgtaa 
      tttagctaa atcgggtca gtttgtgca aaatgtcgg 
      agcaactga aagtcggtc agaaagtca aagtgaccg 
      gtaaagacg tccaggggg ttattgcgt tcatcggcc 
      ccacgagct ttgcggccg acacatgga tcggtctca 
      agctggacg agcccaagg gtaagaaca acgggagtg 
      ttcaggggg ttgaatact tcaagtgcg aggacaagc 
      acgggctgt ttgtgaagc cgtcgcagg tgatccccc 
      tcgacgagc atggcaagc cgctccggg acgccggag 
      aggagaccc ccaaggctc gggccaggc ctagcagtt 
      ctcgcttgt cactggcca gtagccggc agtctttgg 
      ccgatagcc gccagtcac tgtccggca gccgccaat 
      cgcttgcag gaagtcgcc aatccctta tggggagtc 
      gtagtcact tggcctcac cgattgttg aaaagtcag 
      atgcggggg atcacccga gccaaatcc ccaaacggg 
      cctcattta ttgagaccg gctttgtgg aaaccctca 
      atccacaat tcacaccag gccaagtga tcacgacca 
      caccgactc caattacct ccgttgacg agaagatta 
      acgtaatcc agctgcaac aagagatcg aaaatcgca 
      accaacaaa tacgcgatc tgggcgaga agttggaaa 
      ctttgaaaa ttaagcgcc aggaggaca aggagaagt 
      tgaaggagt tggataaat tgaaaatcc agttggagc 
      aattggttg aattcaaga cgaaaatta tggaagtgc 
      aggcgagtt tgcagaggg aggtgcaaa gggccaagc 
      aggaggcga aagaagcgg tcgaggcca aggaggcgc 
      acgctgagg aagtggccg acttggccg aagccgtcg 
      aaatggcca cccttgaca aggaaatgg cggaggaaa 
      aggcagaaa ccttgcagc tggaattgg aagtgtgca 
      aagagaagt tggaagagg tgacgctcg acctgaaaa 
      ttctcaaaa cggagatgc aagaacctg gtggaactt 
      cagcaagtg gggaagaag ccgtttcca cctacgaag 
      tgaaacaac tccagcagc aaaatgccc gacttcggg 
      aaactctag tcaggttga gggatctct cagctcacg 
      acaaacacg aatatcaga aacttctaa aagacatcg 
      accagaaga aatccgaaa ttgtcgagt tggggaaaa 
      cgaaggaaa agttgagtg ccagggttg aagaaatgg 
      agcaacaag ttgccgatc ttcaagaac aggtcgatg 
      cggcgatgg gcgccgaag aaatggtcg taatcctcg 
      gcgagcaga agctcaccc tggaggaga aagtggccc 
      aactcctcg aagaagtcg ccgaactgg aagccctcc 
      aagacatga acgaccaac tggtcgaaa gcaacgccg 
      agctggaag ccgaactgc gcgaagacc tcgacatgg 
      cccgaatgg ccgccaaac aggcgatgc gcgaccgcg 
      acgccgcct tggaaacaa tagccgacc gcgaagcca 
      ctctcaaca aattccgcg aactcgtcc aaaaactcc 
      aagagcagt cgctgcagc tgcaaagtc ggctcgaaa 
      ccgagtcga gcaaacccg tctcagctc tgcccgaaa 
      tcgtcgact tcacgaaaa tgttcaacg agacgaagg 
      cccacacca aagctatcg acttggagc tgagacgcg 
      ttgaaatcc aacagctgc aaagccaca tcaagttct 
      tgacctctt acatgccgg attcgttca tgaaccgcg 
      gcggggatt acgacgctg tgctggtgc tgctgctgg 
      tcttgcgga tgattcaga agacggaga ttctgatcg 
      ggcagatca aggacaagt ttccggggg ttgataaga 
      ttgataggg cggcgattt tgaaagggc atgctgtgg 
      agcagttct cgttcaggt gcagggctt cgttctata 
      tttatgccc tacagtcga ttttgcacc agtattact 
      atgcgttaa atacgtgta aaacagagg cacttctca 
      aagtcggag ctacgtatc ctgagatgg cttcctacg 
      agaaaatca ttgatgggt tcattgaat tggtgaaac 
      gcgatcaac tggacgaga atgtaccga ctgaagcac 
      tcgaaaaat gtgttggat atttcaata cactgtttc 
      ctgtgcttc taggaccgg aaaatcgcc tcaatcaca 
      cgcaattgt tggtcgaca atgttaaaa gtttaacgt 
      cggcgtgtg acggcttta ataacgatt ctatcgtca 
      tcagaaact tgattgaga ctgccaatg ttggtgaca 
      tcggattgt tagcccaac acgtcataa caacatctg 
      aacagttgc aacaacaac taaaactga taaaacggc 
      gccttccgc ccgactcga acgttgcca acatcggtt 
      taaacaagg aagtttttg agaacttgt accagtgtt 
      accaacact gcggccgca tcataaaaa cattgcaag 
      acatcgtca agaactcag tccagttga tgacatcta 
      gcggagaac tggaaaaag gactcccac aggacaaaa 
      tcaaagaaa tcgcgttga atgccagcg ataagatct 
      acgaacagg acgacttag gtccagtgc aaagtatta 
      aaaattcgc tgagtttcg tagtcactc agacgacgc 
      aaattgcgc agtttttgc aagataacg agtacgaaa 
      ttgcgacgg ctaataaaa acgaggaga agcccatac 
      ctccgatcc aaattcggg ccgatgctg tgaaaaaag 
      agctcgaac aaacgaaaa ctttgacga gcaaattgg 
      agaacaaag agtccgata ttaaagagt tgcgtaaag 
      cactcaaag agaaacaag agcaattat ccgaaatga 
      ccatacgga aggaattag ctgagaaaa agttgggta 
      acgtcaata aagattacg agttgacga ttgaaaagc 
      tgcaaagga agctggaag aggcgcaca ataactaca 
      aaaagaagg agaaggagt tcgaggaga ctttagacc 
      atctccaga ccgatatcg attcgctcg agaatgaaa 
      aaggcgaaa tgaaggaga agttaaaac tgctctcga 
      agaaaacac aaatggagt tgtcaactt caagaagcg 
      cgtccggtt cccaattat ccgcccaac aatctctag 
      gtccaagtc tcccagctg tggtcaaag actcgccct 
      tgctcctgc aagaaattg agagtctcc ggaagctgt 
      ttcaccaag aacgcaacg agagaatca aactcgaaa 
      atgagaaaa tcaaaaagg agttggaca gtttggctc 
      ccttgccct cgttcaaga ccacaccgg acgaagttc 
      tggataaat tattcaaag agggggcgt tacttaaac 
      aggaaattt tgatgagtt tggctaaac cgaagttcc 
      cgcaaattt acaaagtca agccgggga atgggccag 
      ctgcttgga agaaacatt tcgctgagg aaaacgaca 
      agttggcgg atctcaaca ggcgagcgc gcgagttcc 
      agacgaagg tagccaatg agattatca agcggaaga 
      tggggggga gggtagaag cggatttcg cagtttttc 
      ccacgattg agatggtta aggcattga gtgagagta 
      agccggtga atatcggct acgtgaaaa tcccgaaga 
      gctacttgc cgaaggggg agaagcctc ggatcgttg 
      acttggagt tggacttta tcaacttgc agaagatcc 
      tgcagtcgc tatcgtgtt aacttattt tctataact 
      gtaataaat tgaattaat tggt
    • >TC012455 RB
      tcaaaagag tgccaagtt cctggttgt cttgtattt 
      tcctcgctt tatttaata attttactg gcataaaat 
      aacataaac cctttattg gaatagtaa ataatgtaa 
      tttagctaa atcgggtca gtttgtgca aaatgtcgg 
      agcaactga aagtcggtc agaaagtca aagtgaccg 
      gtaaagacg tccaggggg ttattgcgt tcatcggcc 
      ccacgagct ttgcggccg acacatgga tcggtctca 
      agctggacg agcccaagg gtaagaaca acgggagtg 
      ttcaggggg ttgaatact tcaagtgcg aggacaagc 
      acgggctgt ttgtgaagc cgtcgcagg tgatccccc 
      tcgacgagc atggcaagc cgctccggg acgccggag 
      aggagaccc ccaaggctc gggccaggc ctagcagcg 
      tcggtacaa aacccaaac ctacaactt ctcgcttgt 
      cactggcca gtagccggc agtctttgg ccgatagcc 
      gccagtcac tgtccggca gccgccaat cgcttgcag 
      gaagtcgcc aatccctta tggggagtc gtagtcact 
      tggcctcac cgattgttg aaaagtcag atgcggggg 
      atcacccga gccaaatcc ccaaacggg cctcattta 
      ttgagaccg gctttgtgg aaaccctca atccacaat 
      tcacaccag gccaagtga tcacgacca caccgactc 
      caattacct ccgttgacg agaagatta acgtaatcc 
      agctgcaac aagagatcg aaaatcgca accaacaaa 
      tacgcgatc tgggcgaga agttggaaa ctttgaaaa 
      ttaagcgcc aggaggaca aggagaagt tgaaggagt 
      tggataaat tgaaaatcc agttggagc aattggttg 
      aattcaaga cgaaaatta tggaagtgc aggcgagtt 
      tgcagaggg aggtgcaaa gggccaagc aggaggcga 
      aagaagcgg tcgaggcca aggaggcgc acgctgagg 
      aagtggccg acttggccg aagccgtcg aaatggcca 
      cccttgaca aggaaatgg cggaggaaa aggcagaaa 
      ccttgcagc tggaattgg aagtgtgca aagagaagt 
      tggaagagg tgacgctcg acctgaaaa ttctcaaaa 
      cggagatgc aagaacctg gtggaactt cagcaagtg 
      gggaagaag ccgtttcca cctacgaag tgaaacaac 
      tccagcagc aaaatgccc gacttcggg aaactctag 
      tcaggttga gggatctct cagctcacg acaaacacg 
      aatatcaga aacttctaa aagacatcg accagaaga 
      aatccgaaa ttgtcgagt tggggaaaa cgaaggaaa 
      agttgagtg ccagggttg aagaaatgg agcaacaag 
      ttgccgatc ttcaagaac aggtcgatg cggcgatgg 
      gcgccgaag aaatggtcg taatcctcg gcgagcaga 
      agctcaccc tggaggaga aagtggccc aactcctcg 
      aagaagtcg ccgaactgg aagccctcc aagacatga 
      acgaccaac tggtcgaaa gcaacgccg agctggaag 
      ccgaactgc gcgaagacc tcgacatgg cccgaatgg 
      ccgccaaac aggcgatgc gcgaccgcg acgccgcct 
      tggaaacaa tagccgacc gcgaagcca ctctcaaca 
      aattccgcg aactcgtcc aaaaactcc aagagcagt 
      cgctgcagc tgcaaagtc ggctcgaaa ccgagtcga 
      gcaaacccg tctcagctc tgcccgaaa tcgtcgact 
      tcacgaaaa tgttcaacg agacgaagg cccacacca 
      aagctatcg acttggagc tgagacgcg ttgaaatcc 
      aacagctgc aaagccaca tcaagttct tgacctctt 
      acatgccgg attcgttca tgaaccgcg gcggggatt 
      acgacgctg tgctggtgc tgctgctgg tcttgcgga 
      tgattcaga agacggaga ttctgatcg ggcagatca 
      aggacaagt ttccggggg ttgataaga ttgataggg 
      cggcgattt tgaaagggc atgctgtgg agcagttct 
      cgttcaggt gcagggctt cgttctata tttatgccc 
      tacagtcga ttttgcacc agtattact atgcgttaa 
      atacgtgta aaacagagg cacttctca aagtcggag 
      ctacgtatc ctgagatgg cttcctacg agaaaatca 
      ttgatgggt tcattgaat tggtgaaac gcgatcaac 
      tggacgaga atgtaccga ctgaagcac tcgaaaaat 
      gtgttggat atttcaata cactgtttc ctgtgcttc 
      taggaccgg aaaatcgcc tcaatcaca cgcaattgt 
      tggtcgaca atgttaaaa gtttaacgt cggcgtgtg 
      acggcttta ataacgatt ctatcgtca tcagaaact 
      tgattgaga ctgccaatg ttggtgaca tcggattgt 
      tagcccaac acgtcataa caacatctg aacagttgc 
      aacaacaac taaaactga taaaacggc gccttccgc 
      ccgactcga acgttgcca acatcggtt taaacaagg 
      aagtttttg agaacttgt accagtgtt accaacact 
      gcggccgca tcataaaaa cattgcaag acatcgtca 
      agaactcag tccagttga tgacatcta gcggagaac 
      tggaaaaag gactcccac aggacaaaa tcaaagaaa 
      tcgcgttga atgccagcg ataagatct acgaacagg 
      acgacttag gtccagtgc aaagtatta aaaattcgc 
      tgagtttcg tagtcactc agacgacgc aaattgcgc 
      agtttttgc aagataacg agtacgaaa ttgcgacgg 
      ctaataaaa acgaggaga agcccatac ctccgatcc 
      aaattcggg ccgatgctg tgaaaaaag agctcgaac 
      aaacgaaaa ctttgacga gcaaattgg agaacaaag 
      agtccgata ttaaagagt tgcgtaaag cactcaaag 
      agaaacaag agcaattat ccgaaatga ccatacgga 
      aggaattag ctgagaaaa agttgggta acgtcaata 
      aagattacg agttgacga ttgaaaagc tgcaaagga 
      agctggaag aggcgcaca ataactaca aaaagaagg 
      agaaggagt tcgaggaga ctttagacc atctccaga 
      ccgatatcg attcgctcg agaatgaaa aaggcgaaa 
      tgaaggaga agttaaaac tgctctcga agaaaacac 
      aaatggagt tgtcaactt caagaagcg cgtccggtt 
      cccaattat ccgcccaac aatctctag gtccaagtc 
      tcccagctg tggtcaaag actcgccct tgctcctgc 
      aagaaattg agagtctcc ggaagctgt ttcaccaag 
      aacgcaacg agagaatca aactcgaaa atgagaaaa 
      tcaaaaagg agttggaca gtttggctc ccttgccct 
      cgttcaaga ccacaccgg acgaagttc tggataaat 
      tattcaaag agggggcgt tacttaaac aggaaattt 
      tgatgagtt tggctaaac cgaagttcc cgcaaattt 
      acaaagtca agccgggga atgggccag ctgcttgga 
      agaaacatt tcgctgagg aaaacgaca agttggcgg 
      atctcaaca ggcgagcgc gcgagttcc agacgaagg 
      tagccaatg agattatca agcggaaga tggggggga 
      gggtagaag cggatttcg cagtttttc ccacgattg 
      agatggtta aggcattga gtgagagta agccggtga 
      atatcggct acgtgaaaa tcccgaaga gctacttgc 
      cgaaggggg agaagcctc ggatcgttg acttggagt 
      tggacttta tcaacttgc agaagatcc tgcagtcgc 
      tatcgtgtt aacttattt tctataact gtaataaat 
      tgaattaat tggt
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