Status
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Gene information
General information
TC008640 Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007422.5: 13517323..13531805
Sequence information
Transcripts / Proteins (1) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    TC008640
    Gene ontology

    GO terms for Tribolium

    • {{ goTerm.term }}
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    There are no GO terms for Tribolium at the moment. You can help the community by providing some GO terms for this gene.


    GO terms for the homologous Drosophila genes


    Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term - use "graph views" to browse related terms ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.


    Gene
    {{ goGene }}
    The Tribolium gene the GO term is assigned to.
    GO ID *
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    The ID of the GO term you assign to the gene. Please enter only the ID of the GO term with proceeding 'GO:'. This information is mandatory.
    Evidence
    {{ blurEvidenceResult }}
    The evidence code describes with which method the function or location, expressed by the GO term, was show for this gene. Please refer to this page for a definition of the evidence code and a decision tree.
    Reference *
    {{ blurReferenceResult }}
    The reference where the function or location is described for the gene. Please enter a PubMed ID. This information is mandatory.
    Quotation
    If you paste here the relevant section of the reference it is for us a great help to review your annotation. The quotation may be also be displayed to the users of iBeetle-Base.
    Name
    You may enter your name. The contact information can help us to clarify any questions. If you agree, we may show your name on this page to honor your contribution.
    Email
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    Publish name
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    * : mandatory fields
    For help on how to submit larger datasets or non experimental data please contact us.
    iBeetle screen iB_01377

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 10.0% (includes death as pupa, adult)

    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: < 50
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 40.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 40.0% (includes death as larva, prepupa, pupa, adult)

    larva lethality - Number of animals showing the phenotype: 4 (11 dpi)
    Days post injection


    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC008640 RA
      MAEDDTKSI KSTKSTKST KSTKSKKDD KAVEDEEDE 
      RLEFILAYF TKSYRLKQE KWNKMIAID ENKKLILNF 
      LNNPQEKFM IITITSAGL LTPFKQYNS AIRSKYTYF 
      IKKKEEVVT MENFADVIL FGDMAAKPI DELAVLLDT 
      ILIPLLANP GNQKGWPQV VADDVVAHV RNFKNSVEQ 
      IRGAMKSQT ILPMPQGMS RLFEAISQF EETEGTNID 
      LVLKASLES GVTKWSNVC SEILKQSST IAFAGGNHP 
      SPSAEVEFW KARLKNLEF IYDQLRDPR VKQVGKYLQ 
      MTKSAYFST FKNMFKDIV AGVIEARDI CLYLKPMVT 
      HFSNFEDGE LFENEHNIK PLLHCMGLI WANSKYYCA 
      NEKMVILFR EIANMLIDA SNRMLDPSS IFQGEPDEM 
      FEKIDKTLH ILELFMDSF EFVRDNLAT YFKREDEEM 
      PALWTFHKR TVFQRLLDF IDRLRLIKA ILATNLEFS 
      KLEKVEFGG IKGRLLSQK CEQIFDEFG TAYNVFNSI 
      QYDPCDTSD LNILKDNND FHAKCADFD KRLAAIFSQ 
      AFDDCYNLE SIFKFLAII GNLLERSVI RDEITPKYP 
      RIIDIFNEE LDTVKIIFD EGKKNGIPI DKNFPPVAG 
      TLMWISKLR QRIEKPGDD LKLLEDDII KSEEAHHSF 
      EKYDHMMRI LDDEGKEVF GNWCKSIPQ QIETSMAKF 
      ELIRKPENL IHLNFDPEL VAALREIRY MKFLEIPDV 
      PQEALDLFE KVELLFECQ QKFNRVVNW YNHLKKNTL 
      KVEYNLIEP EMKQIDELL QSVLDAITW STHDEATLS 
      AIYEKVKDL SDRVVQCQK NMTAIEATL DAWVEAPLF 
      ERREGKKEN LLYLEDRSE RTTKRFAQI ENSHEEIKK 
      LLEVNYRLF FNIPEPVEE PVDESSPEE EVAEPPPTP 
      KKGKKGKKP VETPKEKEK EKEKEKGKK EKGKKGGKG 
      KKKKQKALE DAEAEMQEE PADPYENYR KEHWSKYLE 
      YVDQLVKNK LVAAVHNSL VYLLNESGD LAPITPLFE 
      LSLELHDPD IVFQPSINL TDDNNFVEE ITECVEDIF 
      KMGEVMKRV NPESEDQHY FYEVKSDKN LAKMTEELL 
      SRIMLMRED AFEYLKAFD EFTHIWTDD RHEYLRQFL 
      LFGRLLSPE EHDRIAELK ETPPSVQQF KEQIDFYDD 
      MYKKVEAMS NEKILEGDW MKIDVRPLK QAILNTICK 
      WGNLFKQHL YDHVITSLN DLDSFIVEA IQAMQVTLE 
      EDDYDGLLK VMGYLFKVK ERQLETDNM FQPLKEIMD 
      LLFEYGMEF PEDVHVQLQ EIPDRWQQC KKVAATTKQ 
      NVAPLQALQ VNAIKRRIN LFEIRQAMY RDMFKKLPF 
      FNWSCKDVY SLLDKTNFE LTELETEMA KLQEQANLF 
      ELTLPEFKP MNQARKEIR QIKQLWDYV HIFRSCIDE 
      WKKTPWKKI DVEAMEMEC KKFGKEVRA MDKELRGWD 
      VYIQLEAVI KNMLTSLRA VTELQNPAI RERHWKQLM 
      QATKVKFVM DDSTTLSEL LALNLHEYE DEVKNIVDK 
      SVKEMAMEK VLKELNATW TNMMFATEV HERTNLRLL 
      VASEELIET LEENQVALQ NMMTSKFID FFLEEVSDW 
      QKKLSNADQ VIQVFFEVQ RKWCYLESI FIGSEDIRS 
      QLPEDSRRF EKIDRDFKE VLSEMLKDL NVVRSTNKP 
      GLYDKLDGI LGQLILCEK ALNDYLETK RLAFPRFYF 
      VSSADLLDI LSNGNQPDL IQRHLTKLF DSLAKLKFE 
      KEGGKNSKR AYGMISKEN EEHVQFSQI CDCTGKVEV 
      WLNRVIDVM RKTLQSCFA EAISTYDEK PREVWIYDY 
      PAQPALCGT QIWWTTEVN IAFARLEEG YENALKDYQ 
      RKQINQLNA LINLLLGDL TAGERQKIM TICTIDVHS 
      RDVVAKMIA IKVENSQAF QWQSQLRHR WDDKIKDCF 
      GNICDAQFR YQYEYLGNT PRLVITPLT DRCYITLTQ 
      SLHLIMGGA PAGPAGTGK TETTKDLGK ALGMMVYVF 
      NCSEQMDYK SIGNIYKGL SQTGCWGCF DEFNRISIE 
      VLSVVAVQV KVIQDAIKD KKAKFNFLG QDIVLVPTV 
      GLFITMNPG YAGRTELPE NLKALFRPC AMVVPDFAL 
      ICEIMLVAE GFQEARLLA RKFITLYTL CRELLSKQD 
      HYDWGLRAI KSVLVVAGS LKRGDRQRP EDQVLMRAL 
      RDFNIPKIV TDDVPVFMG LIGDLFPAL DVPRKRDPD 
      FEKTIKKSA VDLKLQPED GFVLKVVQL EELFAVRHS 
      VFVIGNTGT GKTMVWKTL NKTYQNQKR KPIYNDINP 
      KAVTNDELF GVINPATRE WKDGLFSVI MRDQANLTG 
      DGPKWIVLD GDIDPMWIE SLNTLMDDN KVLTLASNE 
      RIALTSAMR LLFEIASLR TATPATVSR AGILYINPA 
      DLGWNPYVA SWIDTRTQQ NEKANLMIL FDKYVPPCL 
      EILRHKLKK ITPISEVAH ISMLCFLLD CFLTPQNVP 
      PDCPKEWYE IYFVFCTVW AFGSALFQD QIVDWRNEF 
      SKWFVNEFK TIKFPVTGG NVFSYYVEE ETKRFAPWT 
      ELVPEFELD PDIPLQATL VNTAETTRI RFFMDHLME 
      KRIPVMLVG PAGSGKSVI VAEKLTSLS EHYAVTNVP 
      FNFYTTSEM LQRILEKPL EKKAGRVFG PPGNKTMIY 
      FVDDMNMPE VDKYFTVQP HTLIRQYMD YQHWYDRQK 
      LTLKDIHNV QFVSCMNPT AGSFTINPR LQRHFCVFA 
      VSFPSQEAS NHIYYSIIS QHFESEHNR FGKNIFKLS 
      ASLVDAAVF LHQKVAASF LPTAVKFHY TFTLRDLSN 
      IFQGMLFTT GDAIKTQTD LIRLWMHEC GRVYGDKLV 
      EKRDLDTYK KLVIESVKK SFEELDENE VFEEPLIYC 
      HFAEGMGDP KYFPIHEFD HLSKLLHEA LAGYNDLVA 
      AMNLVLFED AMYHICRIN RIMEAPRGN ALLIGVGGS 
      GKQSLTRLA SFISSFEVF QVQLKKGYS MTDLKADLA 
      QLYLKAGLK SVGIVFLMT DAQVPQEIF LVAINDMLA 
      SGEISELLP DEDVENVIN AVRGEVKQS GLQDTRENC 
      WKFFIDRVR RLLKTVLCF SPVGSTLRV RARKFPALV 
      NCTSIDWFH EWPREALES VSKRFLAEI EVLPKDLVP 
      SVSNFMSDV HGVVNTMSE LYLQNEKRY NYTTPKSFL 
      EQIALYSKL LYEKTKNLE DNIERLESG LLKLASTSE 
      EVDGLKEVL AVQEVELNE KNEAAGKLI AVLSAENEK 
      VAKEQAIAS EEEAKVKLI EEDVSVKQK ICADDLAKA 
      EPALIAAQQ ALNTLNKNN LTELKSFTQ PPEAVVAVT 
      AAVLILFSP KGRIPKDRS WKACKGLMT KVDKFLEDL 
      INYDKENMQ PEVVKATLE YTKNPEFNP EKILSKSVA 
      AAGLCAWVI NILKFYDVF VVVEPKRKA LQKANQELA 
      DARAKLAEL NEKLNYLES QLAILKADF EEATAAKMK 
      CQAEADATT QMIDLANRL VNGLASENI RWRELVKLY 
      RKMIITLPG DVLMITCFI SYVGCFTRR YRTEMVEHH 
      WIPSLKKIE PKIPMSEGL DPLSLLTDD AMVAGWNNE 
      GLPNDRMST ENACILTNS ARWPLMIDP QLQGVKWIK 
      TKYGDSLTV IRLSMKNYL DTIERCIQN GEIILVENI 
      GETVDAVLD PVLGRVLVK KGKAIKIGD KEVDYNPNF 
      RMIMHTKLA NPHYKPEIQ AQTTLINFT VTRDGLEEQ 
      LLAEVVKAE RPDLESLKA NLTKQQNDF KIILKRCED 
      NLLFRLSSA TGNILGDVE LVENLETTK KMSTEIEEK 
      VKEAKITSV KIDEAREQY RPCSARASL LYFILNDLC 
      RINAIYQFS LKAFSVVFK DALSKAVPA EKLKDRVVN 
      LLDSITFSV FMYTTRGLF ECDKLIFMA QMAFQILLH 
      AKEIDHAEL DFLLRYPVV PNLTTPVDF LTNQSWGGI 
      KALSEFDDF RGLDKDLEG SAKRWRKFV DSECPEKEK 
      FPGEWKNKT ALQHLCMMR ALRPDRMTY AVRCFIEEK 
      LGAKYITAR SVEFAKSYE ETSSSTPVF FILSPGVNP 
      LKDVEKLGK KLGFTFDSG NFHSISLGQ GQEIVAENA 
      MDLASERGD WVILQNIHL VERWLSTLE KKMEQCAES 
      AHQKFRLYL SAEPNADPQ VSVIPQGIL ESSIKITNE 
      PPTGMYANL HKALDNFSQ ETLDMCTKE AEFKLILFA 
      LCYFHAVVA ERRKFGPQG WNRNYPFNV GDLTISVNV 
      LYNYLESNS KVPYEDLRY LFGEIMYGG HITDDWDRR 
      LCRNYLMEY LQPELLEGD LQFAPGFFA PPNTDYVGY 
      HRYIDDRLP PESPYLYGL HPNAEIGFL AYTSEVMFR 
      TIFEMQPRD AGASVGHGF SREDKVKST LEDIQDRLP 
      EEFPVAEMM AKVEDRTPY IIVAFQECD RMNSLTREM 
      KRSLRELDL GLKGELTIT SDMEVLEEA LFMDQVPDS 
      WSVKAYPSM LPLGQWVAD LGARIKELE GWVTDFSMP 
      PTVWLGGFF NPQSFLTAI MQQTARKNE WPLDKMCLL 
      TDVTKKQKE EFGAAPREG AYVHGLFME GARWDTQLG 
      SIADAKLKE LFPVMPVIF IKAITQDKQ DLRNMYDCP 
      VYKTRTRGP TFVWTFNLK TKEKASKWT LAGVAILLQ 
      I
    CDS sequence
    • >TC008640 RA
      atggccgaa gatgatacc aagtctatc aaatcgacc 
      aagtcgaca aagtcgacc aagtccacc aagtccaag 
      aaagatgat aaggctgtc gaagacgag gaggatgaa 
      cgactcgag ttcatcctc gcttatttt acaaaatcc 
      tacagactc aagcaggaa aagtggaat aaaatgatc 
      gcaatagac gaaaataag aaacttatt ttaaatttt 
      ctgaacaac cctcaagag aaatttatg attattacg 
      ataacatca gccggtctc ctgacccct tttaagcaa 
      tacaacagc gctataaga tccaaatac acttatttc 
      atcaaaaag aaggaggaa gttgtgact atggaaaac 
      ttcgccgat gttattctt tttggcgac atggccgca 
      aaacccatc gacgagttg gccgttctc ttggacaca 
      attttgatc cctttgctt gcaaacccc gggaatcag 
      aaaggatgg ccacaggtg gttgcagac gacgttgtc 
      gcgcatgtc cggaatttt aaaaattca gtcgaacaa 
      attcgggga gcaatgaaa agccaaaca atcttgcca 
      atgccgcaa ggcatgtcc cggcttttc gaagcaata 
      agccagttt gaagaaaca gaaggcact aatattgat 
      ttggtcctg aaagcgtct ctcgaaagt ggtgtcacg 
      aaatggtca aacgtttgc agcgagatt ctgaaacaa 
      tcgtcaact attgctttc gccggcgga aatcatccg 
      tcaccaagt gccgaagtg gaattctgg aaagctcgc 
      ctcaagaat ctagaattt atttacgat caactgcga 
      gatcccaga gtgaagcaa gttgggaaa tatttgcaa 
      atgaccaaa agtgcctat ttctcaact tttaagaac 
      atgttcaaa gacattgtt gctggcgtt atcgaagcg 
      agagacatt tgtttgtat ttgaaacca atggtgact 
      cacttctcg aatttcgaa gacggcgag ttgttcgaa 
      aacgaacac aacatcaag cctttgctg cactgcatg 
      ggcctgatt tgggccaac tcgaagtac tactgcgcc 
      aacgagaaa atggtgatc ctgtttagg gaaatagca 
      aatatgttg atcgacgcc agtaatcgt atgctagac 
      cccagctca attttccaa ggcgaacct gacgaaatg 
      ttcgaaaag attgacaag actctgcac atcttggag 
      ctttttatg gactcgttc gagttcgtt cgcgacaat 
      ttggccact tattttaag agagaggat gaagaaatg 
      ccggcactt tggacgttt cataaaagg acggtgttt 
      caaagactg ctcgacttt attgaccgt ctgaggctg 
      attaaagca atcttggcg actaatcta gagttcagc 
      aagttggag aaggttgag tttgggggt atcaaaggc 
      cggttgttg tcccaaaag tgtgaacaa atttttgat 
      gaattcggt accgcctac aatgttttt aattcgatt 
      cagtatgat ccttgcgac accagtgat ttgaatatc 
      ctcaaggat aacaacgat tttcacgca aaatgtgcc 
      gactttgac aaaaggtta gcagcgatt ttctcccag 
      gccttcgat gattgctac aacctcgaa agcatcttc 
      aaatttctc gcaatcatc gggaatttg ctcgaaagg 
      tccgttatc agagacgaa ataactcca aaataccca 
      agaattatt gacatattc aacgaggaa cttgatacg 
      gtgaaaatc atttttgac gaaggcaaa aagaatggt 
      attcccatc gataaaaat ttccccccg gtcgctgga 
      acccttatg tggatatct aaattgagg caaaggatt 
      gaaaaacca ggcgatgat ttgaaatta ttagaagat 
      gatattatc aagtccgag gaggctcat cattcgttt 
      gaaaaatac gaccacatg atgcgaatt ttggacgat 
      gagggcaag gaagtgttt ggaaattgg tgcaagtca 
      attccgcaa caaatcgag actagtatg gccaagttc 
      gaacttata cgtaaacct gagaacttg attcatttg 
      aattttgat ccggaattg gtagcggcc ttgcgggaa 
      attcggtac atgaagttc ttagaaatt ccggatgtg 
      cctcaagag gcgttagat ctgttcgaa aaggttgaa 
      cttttgttc gaatgtcaa cagaaattt aacagagtt 
      gtgaattgg tataaccat ctcaagaag aacacgctt 
      aaggtggaa tacaactta attgagccg gaaatgaaa 
      caaatagat gagttgctc caatcagtg cttgatgct 
      attacgtgg agcactcat gatgaggca actcttagt 
      gccatttat gaaaaagtt aaagatctg tcggatcgt 
      gttgtgcaa tgtcagaag aatatgact gctatcgaa 
      gccacgctg gatgcctgg gttgaggct ccactgttt 
      gaaaggaga gaaggcaaa aaagagaat ctgctatat 
      ctcgaagac cggtctgaa cgtactact aaaagattt 
      gctcaaatt gagaatagc cacgaagaa ataaaaaaa 
      ctcctagaa gttaactat cgattgttc tttaatatt 
      cctgagccg gttgaagaa ccggttgat gagtcgtcg 
      cctgaagaa gaagttgct gagccacca cccacccca 
      aaaaaaggt aaaaaaggg aaaaagcca gtcgaaaca 
      cccaaagaa aaggagaaa gagaaagaa aaagaaaaa 
      gggaagaag gagaaaggt aagaaaggt ggaaaaggc 
      aaaaagaag aagcaaaaa gcccttgaa gacgctgaa 
      gctgagatg caggaagaa cctgcagat ccttacgag 
      aattatcgt aaagaacac tggagcaaa tatttggaa 
      tatgttgat caactagtc aaaaacaaa cttgtagct 
      gcagtccat aatagtttg gtttacttg ctgaatgag 
      tctggcgat ttagctcct attacacct ttgtttgaa 
      ctgtcttta gaacttcat gatcctgac attgtgttt 
      caaccttcg attaatcta acagatgat aataatttc 
      gttgaagaa ataaccgaa tgcgtggaa gatattttc 
      aaaatgggt gaagttatg aaacgggtg aatccggaa 
      agtgaagac cagcattac ttttacgaa gtcaaatca 
      gataaaaat ttggccaaa atgactgaa gagcttctg 
      agcagaatt atgttgatg agagaagat gcgtttgaa 
      tatcttaaa gcatttgac gaatttacg catatttgg 
      accgacgat aggcacgag tatttgcgc cagttcctg 
      ctttttggc cggttgttg agtcccgag gagcacgac 
      agaatcgcg gaactaaaa gagacccca ccgtctgtg 
      caacagttt aaggagcaa attgatttt tacgacgat 
      atgtacaaa aaggtcgaa gctatgagc aatgaaaag 
      attcttgaa ggtgactgg atgaaaatt gatgtccgg 
      cccttgaaa caagctatc cttaacacg atttgcaaa 
      tggggcaat cttttcaag cagcatctt tacgatcac 
      gttattact agcctcaat gatctcgac agtttcatt 
      gtggaggca attcaagcc atgcaagtc acattagag 
      gaggacgac tacgacggc ttattaaaa gtgatggga 
      tatttgttt aaagtgaag gaaagacag ttggaaacc 
      gataatatg ttccagcca ttgaaggaa atcatggat 
      ctgctgttc gaatatggg atggaattt ccggaagac 
      gtgcacgtc caattacag gagattcca gacaggtgg 
      caacaatgc aagaaagtt gccgcaact actaaacaa 
      aacgttgca ccacttcaa gcccttcaa gtgaatgcg 
      atcaaaaga cgaattaat ttgttcgaa atccgacaa 
      gcgatgtat agagacatg tttaagaaa cttcccttc 
      tttaactgg agctgtaaa gatgtgtac tctttgtta 
      gataaaact aatttcgaa ctgactgaa cttgagaca 
      gaaatggcg aaattgcaa gagcaagcc aatttattc 
      gaactaacg ctgcctgag tttaaacca atgaatcag 
      gcgaggaag gaaattagg caaattaaa cagttgtgg 
      gactacgtc catattttc cggtcgtgt atcgacgaa 
      tggaagaaa accccctgg aaaaaaatt gacgttgag 
      gcgatggaa atggaatgt aaaaaattc ggcaaggag 
      gtgcgagcc atggataag gaattaagg ggttgggat 
      gtttacatc cagctggaa gcggtaata aagaatatg 
      ttaacgtcg ttacgagcc gtcaccgaa ttgcaaaat 
      ccggcgatt agggagagg cactggaag cagttgatg 
      caagctacg aaggtgaaa tttgtaatg gacgattcg 
      accacactc agcgaattg ctcgccttg aatttgcac 
      gagtatgaa gatgaagtt aagaacatt gttgataaa 
      tcagtcaaa gaaatggcg atggagaaa gtcctaaaa 
      gaattaaac gcaacctgg actaacatg atgtttgcg 
      accgaagtc cacgaacgc acaaatttg agacttttg 
      gtggcttcc gaagagtta attgagact cttgaagag 
      aaccaagtt gctctccaa aacatgatg acgtccaaa 
      tttatcgat ttcttcctt gaagaggtt tccgactgg 
      cagaaaaaa ttatcgaat gctgatcaa gtcatacaa 
      gtgtttttc gaagtgcag cgcaagtgg tgctacttg 
      gaaagtatt ttcataggg tctgaagac atcagaagc 
      caattacct gaagattca agacggttt gagaaaatc 
      gatagggat tttaaagag gttttgtcc gaaatgctg 
      aaggattta aatgtggtg aggtccacc aacaagccc 
      ggactttac gacaagctt gacggtatt ttggggcaa 
      ttaattttg tgcgaaaaa gccctcaac gactatttg 
      gaaacgaaa agattggca tttcctcgc ttctacttc 
      gtatcgtct gccgattta ttagatatt ttgtctaac 
      ggaaatcaa ccagatctc attcagaga catttgacc 
      aaactattt gattctctg gctaaactg aaatttgaa 
      aaagaaggt gggaaaaat tcaaagaga gcctatgga 
      atgatttcc aaagaaaat gaagaacat gtgcaattc 
      agccaaatt tgtgactgc actggcaaa gtggaagtt 
      tggttaaat cgtgttatt gatgtaatg agaaaaacc 
      cttcaaagt tgtttcgct gaggctata tcaacctac 
      gatgaaaaa cctagagag gtttggatt tacgactat 
      ccagcacaa ccggcactt tgcggcacg caaatttgg 
      tggacaact gaggtaaac attgctttc gcaagactg 
      gaagaaggt tacgaaaac gccctaaaa gactatcaa 
      agaaaacaa atcaatcag ttaaatgcc cttattaat 
      ctcttgttg ggtgatttg actgcaggc gagcgccaa 
      aagatcatg accatttgt accatcgac gtgcactcg 
      agagacgta gtcgcgaaa atgattgca atcaaagtg 
      gagaattca caagccttt cagtggcaa agtcagttg 
      cgacatcgc tgggacgat aaaatcaaa gactgtttt 
      ggtaatatc tgtgacgcc cagttcaga taccaatac 
      gaatatttg ggcaacacc ccccgactg gtgataaca 
      cccttaact gatcgttgc tacataact ctgactcaa 
      agcttgcat ttaattatg gggggagca cctgccggg 
      cctgcagga accgggaaa actgagaca accaaagat 
      ttggggaaa gctttaggg atgatggtt tacgtgttc 
      aactgttcg gaacaaatg gactataag tctattggg 
      aacatttac aaagggtta tcacagacg ggttgttgg 
      ggttgtttt gacgaattt aaccgaatt tccattgag 
      gtactgtct gtggtagcc gtccaggtg aaagtcatc 
      caggacgct atcaaggac aagaaagct aagtttaat 
      ttcttgggg caagatatt gtcttagtc cccacggtc 
      ggccttttc attaccatg aacccgggc tacgccggc 
      cgtactgaa ctcccggaa aatctaaaa gccctattc 
      aggccatgc gctatggtt gtgcctgac ttcgcccta 
      atttgcgaa atcatgttg gtcgccgaa ggtttccaa 
      gaggctcgt cttctggcg cgcaaattc atcactctc 
      tacacgttg tgtcgcgaa ttattgagc aaacaagac 
      cattacgat tggggtttg agggctatt aagtctgtt 
      ttggtcgtt gcagggtcg ttgaaacgt ggcgataga 
      caacggccg gaagaccaa gtcttaatg cgcgctttg 
      cgtgatttc aacatccct aaaatcgtt acagacgat 
      gtcccggtt tttatggga ctgataggt gatttgttt 
      ccggccttg gacgtgccg agaaagcgt gacccggac 
      tttgaaaaa acgataaaa aaatctgcg gttgatttg 
      aaattgcaa cctgaggac ggtttcgtc ttgaaagtg 
      gtgcaattg gaggagctt ttcgctgtg cgacattca 
      gtattcgtg attggtaac acgggaact ggtaaaact 
      atggtttgg aagactttg aacaagact tatcagaac 
      cagaaaaga aagccgatt tataacgat attaatccc 
      aaagctgtg actaatgat gaattgttt ggggtgata 
      aacccggcc actagagag tggaaagat ggtttgttt 
      tctgtaatc atgagagat caggctaat ttaaccggc 
      gatgggcct aaatggatt gttcttgat ggtgacatt 
      gatcccatg tggattgaa tcattaaac acacttatg 
      gatgataat aaagtgcta actttggcc agcaatgaa 
      cgaattgct ttaacttca gctatgcga ttattattt 
      gaaattgcc tctttacgt actgcaacc ccagccact 
      gtttcaaga gccggtatt ttatacata aacccggcc 
      gatctgggt tggaaccct tacgtagct tcctggatt 
      gataccaga acccaacaa aatgaaaaa gccaatctt 
      atgatactc tttgacaag tatgttcct ccttgtttg 
      gaaatactt cgtcacaaa ttgaaaaaa ataacacca 
      atctctgaa gtagcgcat atttcgatg ctttgcttc 
      ctcttggac tgtttccta acaccccag aatgtccct 
      cctgattgt cccaaagag tggtacgag atttacttc 
      gtattttgc acagtctgg gcgtttggt tcggctttg 
      ttccaagac caaattgtc gactggcgc aatgaattt 
      agcaaatgg tttgtgaat gaattcaaa actatcaaa 
      tttcccgtc actggaggc aacgtcttc agttattac 
      gttgaagag gaaactaaa aggtttgct ccatggacg 
      gaactagta cccgaattt gagcttgat cccgatatt 
      cccttgcaa gccactttg gtcaatacg gccgaaact 
      accaggatt cggtttttc atggatcat ttaatggaa 
      aaacgaatt cctgtcatg ttggtaggg ccggcagga 
      agtggcaaa agtgtgatt gttgcggaa aaactcacc 
      agcttatcc gaacattac gccgttaca aatgtccct 
      ttcaatttt tacactacc tctgaaatg ttgcaaaga 
      attttggaa aaaccctta gaaaagaaa gctgggcgt 
      gtgtttggc cctccgggt aataagact atgatttat 
      ttcgtggac gatatgaac atgcccgaa gttgacaag 
      tattttact gtacaacct cacacgtta attcgccag 
      tatatggac taccagcat tggtatgac cgtcagaaa 
      ctgacttta aaggacatt cacaatgtt cagtttgtc 
      tcctgcatg aacccaacc gccggctct ttcaccata 
      aacccacgg ttgcagaga cacttttgc gtctttgcc 
      gtgagtttt ccgagccaa gaggcgtcg aaccatatc 
      tattacagt attatatcg caacatttt gagtcggaa 
      cataacagg tttggcaaa aatattttc aaactgagt 
      gcttctcta gtggatgcg gcggttttt ctgcaccag 
      aaagtagcg gctagtttt ctgccaacc gctgtcaag 
      tttcattac acatttact ttgcgagac ctttcgaat 
      atttttcaa ggaatgctt ttcacgacc ggagacgct 
      attaaaact cagaccgat ttgatccgg ctttggatg 
      cacgaatgt ggccgcgtt tacggtgac aaactggtc 
      gaaaaacgc gatttggac acttacaaa aagctggta 
      attgagtca gtgaagaaa agtttcgag gagttggac 
      gaaaatgag gtgtttgag gaacctttg atttattgt 
      cattttgct gagggcatg ggggatccg aaatacttc 
      cccattcat gaatttgac catttgagt aaactcttg 
      cacgaagct ttggccggt tataatgat ctagtggcg 
      gcgatgaat ttggttttg tttgaagat gcaatgtat 
      cacatttgc cgcattaac agaattatg gaagctcca 
      agaggtaac gcgctgctc attggagtt ggaggttca 
      ggaaagcag tctttgacg agacttgct tccttcatc 
      tcctcgttt gaagtgttt caagtccag ttgaagaaa 
      ggttactct atgactgac ctaaaggcc gatttggcc 
      caattatat ctaaaagcg ggtttgaag agcgttgga 
      attgtgttt ctgatgact gatgcccaa gtccctcaa 
      gagattttc ctggttgcg attaacgat atgttggca 
      tcgggcgaa atcagtgag ttactgccc gacgaagac 
      gttgaaaat gttatcaat gcagttaga ggtgaggtg 
      aagcaaagt gggttacaa gacacacgg gagaattgt 
      tggaaattt ttcattgat cgtgtccgg agattatta 
      aaaacggtg ttgtgtttc tcaccagtt ggttcgact 
      ctacgagtg cgagcgaga aaatttccg gctcttgtt 
      aactgtact tctatcgac tggttccat gaatggccg 
      agggaagcc ctggaatca gtatcaaag agatttttg 
      gcggaaatt gaagttctc cccaaagat ttagttcct 
      tcagtttcc aacttcatg tcagatgtt cacggagtg 
      gtgaacacc atgtccgag ttgtatcta caaaatgag 
      aaacgctac aactacacc actcctaaa tctttccta 
      gaacagatc gccttgtat tctaaactt ctttacgaa 
      aagactaaa aatttggag gacaatatc gaacgcctc 
      gagtctggt ttactcaaa ctggcatca acttcggaa 
      gaagtggac ggtttgaaa gaagtgttg gcagtccaa 
      gaggtagaa ttgaatgaa aagaatgaa gccgccggt 
      aaactcatt gccgtccta agtgccgaa aacgaaaaa 
      gttgcaaaa gaacaggca atcgctagc gaggaagaa 
      gccaaagtt aaactaatc gaggaggat gttagtgtc 
      aaacaaaaa atctgtgcc gatgatttg gccaaagcc 
      gagccagcg ctaatcgca gcccaacaa gctttaaac 
      accctgaat aaaaacaac ttaactgaa ctgaaatcc 
      ttcacgcaa ccgcctgaa gcggtagtc gctgtaaca 
      gccgctgtt ttaatcctg ttttcgcca aaaggacga 
      attccgaaa gatcgtagc tggaaagct tgtaagggg 
      ttgatgaca aaagtcgat aaattttta gaagattta 
      ataaactat gataaggaa aacatgcaa ccggaagta 
      gtgaaagca actctggaa tatacgaaa aatcccgag 
      ttcaatcca gaaaaaatt ttgagcaag tcggtggca 
      gctgctgga ttgtgtgcg tgggtcatt aatattttg 
      aaattttac gacgtgttt gtcgtggtc gaacccaag 
      aggaaagct ttgcaaaaa gccaatcag gaactggca 
      gatgcgaga gctaaactg gccgagctt aacgagaaa 
      ttgaattat ctcgagtca caattggcg attttgaag 
      gccgatttt gaggaagct acagccgcg aagatgaaa 
      tgtcaggcc gaagctgat gctacgact caaatgatc 
      gatttagct aatcgactt gttaatggt ttggcgtcg 
      gaaaatatc aggtggcga gagttggtc aagttgtac 
      cggaaaatg ataattaca ctgccaggg gatgtgttg 
      atgataact tgctttatt tcgtacgtt ggatgcttc 
      acgagacgg tacagaacc gagatggtt gaacatcac 
      tggataccc tcgctgaaa aaaatcgag ccgaaaatt 
      ccgatgagt gaagggctg gatccctta tccctgctc 
      acagacgat gcaatggtc gcaggatgg aataatgag 
      gggcttcct aatgatcgt atgtcaacc gagaatgct 
      tgtatttta acaaattcg gcaagatgg cccctgatg 
      attgatccc caattgcaa ggagttaag tggatcaaa 
      actaaatac ggcgatagc ttgacagtt attcgactg 
      agcatgaaa aattacttg gacactatt gaaagatgt 
      atccaaaat ggtgaaatt atccttgtt gaaaacata 
      ggcgagacc gtggacgcg gtcttagac cctgttctg 
      ggtcgagtc ttagtcaaa aaaggcaag gcgataaaa 
      atcggtgat aaggaagtg gattacaac cccaacttt 
      aggatgatc atgcacacg aaactggca aatccgcat 
      tacaaaccg gaaattcaa gcacaaact accctcatc 
      aacttcaca gtaacgcga gatggttta gaggagcag 
      cttttggca gaagtcgtc aaagctgaa cgcccagac 
      ttggaaagt ttgaaagcg aatttaacg aaacaacaa 
      aacgatttc aaaattatt ttgaaaaga tgtgaggat 
      aatttattg tttagactt tcctcggcc acgggtaac 
      atactgggc gatgtggaa ctagtcgag aatttggaa 
      acaaccaag aaaatgtcc acggaaatt gaagagaaa 
      gtcaaagaa gctaaaata acttcagtc aaaatcgac 
      gaagcgcgt gaacagtac cgaccatgt tcggctaga 
      gcttcgctc ctttatttc attttgaac gatctttgc 
      cgcatcaac gcaatctat caattctca ttgaaggcc 
      ttcagtgtg gtgtttaag gacgcgtta tctaaagca 
      gtaccggcc gaaaagtta aaagatcgg gtagttaac 
      ttattggac agtataact ttttcggta tttatgtac 
      acaactcga ggtctgttc gaatgtgac aagttgatt 
      ttcatggcc caaatggca tttcaaatt ttgctgcat 
      gctaaagaa atcgatcac gctgaactt gactttctg 
      ttacggtac cctgtagta ccgaacttg acaacccct 
      gtggacttc ctcacaaat cagtcctgg ggcggcatt 
      aaagccctg tcagagttt gacgatttc agaggttta 
      gacaaagac ttggaaggc tcggcgaaa cgttggcga 
      aaattcgtc gatagtgaa tgccccgaa aaagaaaag 
      ttccccggc gagtggaaa aacaaaacc gctttgcaa 
      cacttgtgc atgatgcgt gccctccgc cccgaccgt 
      atgacctac gctgttcgt tgtttcatt gaagagaaa 
      ctcggagcc aaatacata acagccaga tccgtcgaa 
      tttgcaaaa tcttacgaa gaaacaagc tcttcaacc 
      cccgtgttc tttattcta tcgccaggc gtaaatccg 
      ctcaaggat gtagaaaag ctgggcaaa aagctgggt 
      ttcaccttt gattctggt aacttccac agtatttcc 
      ttgggccaa ggccaggaa atcgtggct gaaaacgca 
      atggatttg gcgtcggag cggggcgat tgggtcatt 
      ttgcaaaac attcattta gtcgagcgg tggttgtcc 
      actttggag aaaaaaatg gaacaatgc gccgaaagc 
      gcccatcaa aagtttagg ttgtatttg agcgctgag 
      cctaacgct gatccccaa gtgtccgta atcccgcaa 
      gggattcta gaatcgtcg atcaaaatc acaaacgag 
      ccgccgact ggcatgtat gccaattta cacaaagct 
      ttggacaat ttcagccag gaaacgtta gacatgtgc 
      acgaaagaa gcggagttt aagctgatt ttgttcgct 
      ttgtgctat ttccatgcc gtggttgcc gaaagacgg 
      aaatttggg ccacaaggg tggaacagg aattacccc 
      tttaatgtt ggcgatctc acaattagc gtaaacgtg 
      ttgtacaat tatctggaa agtaacagt aaggtcccc 
      tacgaagat ttgcgctat ctgtttggg gaaataatg 
      tacgggggg catattacg gacgattgg gatcgacgg 
      ttgtgccga aattatcta atggagtat ctccagccc 
      gaattgctg gaaggagac ttgcagttt gcgccggga 
      ttttttgcc ccacctaat acagactat gttgggtat 
      catcgctat attgacgac cgtttgccg cctgaaagc 
      ccctacctt tacggccta cacccaaac gcggaaatt 
      ggcttcttg gcctacact tctgaagtt atgtttaga 
      acaattttc gaaatgcaa ccgcgagat gcgggagct 
      tcggtaggc catggattt tctcgagag gataaggtt 
      aaatcaacc cttgaagat atccaagac cggctcccc 
      gaggagttt ccggtcgcc gaaatgatg gcaaaagtc 
      gaagacagg accccgtac ataattgtg gcgttccag 
      gagtgtgac agaatgaac agtttaaca cgggagatg 
      aagagatcg cttcgggag ctcgacttg ggattaaag 
      ggtgaactt acgattacg tcggacatg gaggtgttg 
      gaagaggcc ctatttatg gaccaagtc cctgactcg 
      tggtccgta aaggcctac cccagcatg ctgcctttg 
      ggtcagtgg gtggccgac ttgggggct agaattaag 
      gagctggag gggtgggtt accgatttc tcgatgcct 
      cccaccgtc tggctgggg ggtttcttc aacccccag 
      tcgttcctc actgccatt atgcaacaa acggctcgc 
      aaaaacgaa tggcctttg gacaaaatg tgtctgttg 
      accgacgtc accaaaaag cagaaagag gagttcggg 
      gcggctcct cgggaaggc gcatatgtg cacggttta 
      tttatggag ggcgcaagg tgggatacg cagctcgga 
      agtattgcc gatgctaag cttaaagaa ttgttccct 
      gtaatgccg gttatattc atcaaggca atcacgcag 
      gataagcag gatttacgg aatatgtac gactgtcct 
      gtttacaaa acaaggact cggggaccg actttcgtc 
      tggactttt aatttaaaa acgaaggag aaggcgtcc 
      aagtggacc cttgcagga gtagcgatt ctgttacag 
      atttaa
    mRNA sequence
    • >TC008640 RA
      agctgttta ttattagca aacagaccg ttaaggtct 
      gacaagtgt tcaaacttt ttaaaaaac tcctgtaat 
      taaatggcc gaagatgat accaagtct atcaaatcg 
      accaagtcg acaaagtcg accaagtcc accaagtcc 
      aagaaagat gataaggct gtcgaagac gaggaggat 
      gaacgactc gagttcatc ctcgcttat tttacaaaa 
      tcctacaga ctcaagcag gaaaagtgg aataaaatg 
      atcgcaata gacgaaaat aagaaactt attttaaat 
      tttctgaac aaccctcaa gagaaattt atgattatt 
      acgataaca tcagccggt ctcctgacc ccttttaag 
      caatacaac agcgctata agatccaaa tacacttat 
      ttcatcaaa aagaaggag gaagttgtg actatggaa 
      aacttcgcc gatgttatt ctttttggc gacatggcc 
      gcaaaaccc atcgacgag ttggccgtt ctcttggac 
      acaattttg atccctttg cttgcaaac cccgggaat 
      cagaaagga tggccacag gtggttgca gacgacgtt 
      gtcgcgcat gtccggaat tttaaaaat tcagtcgaa 
      caaattcgg ggagcaatg aaaagccaa acaatcttg 
      ccaatgccg caaggcatg tcccggctt ttcgaagca 
      ataagccag tttgaagaa acagaaggc actaatatt 
      gatttggtc ctgaaagcg tctctcgaa agtggtgtc 
      acgaaatgg tcaaacgtt tgcagcgag attctgaaa 
      caatcgtca actattgct ttcgccggc ggaaatcat 
      ccgtcacca agtgccgaa gtggaattc tggaaagct 
      cgcctcaag aatctagaa tttatttac gatcaactg 
      cgagatccc agagtgaag caagttggg aaatatttg 
      caaatgacc aaaagtgcc tatttctca acttttaag 
      aacatgttc aaagacatt gttgctggc gttatcgaa 
      gcgagagac atttgtttg tatttgaaa ccaatggtg 
      actcacttc tcgaatttc gaagacggc gagttgttc 
      gaaaacgaa cacaacatc aagcctttg ctgcactgc 
      atgggcctg atttgggcc aactcgaag tactactgc 
      gccaacgag aaaatggtg atcctgttt agggaaata 
      gcaaatatg ttgatcgac gccagtaat cgtatgcta 
      gaccccagc tcaattttc caaggcgaa cctgacgaa 
      atgttcgaa aagattgac aagactctg cacatcttg 
      gagcttttt atggactcg ttcgagttc gttcgcgac 
      aatttggcc acttatttt aagagagag gatgaagaa 
      atgccggca ctttggacg tttcataaa aggacggtg 
      tttcaaaga ctgctcgac tttattgac cgtctgagg 
      ctgattaaa gcaatcttg gcgactaat ctagagttc 
      agcaagttg gagaaggtt gagtttggg ggtatcaaa 
      ggccggttg ttgtcccaa aagtgtgaa caaattttt 
      gatgaattc ggtaccgcc tacaatgtt tttaattcg 
      attcagtat gatccttgc gacaccagt gatttgaat 
      atcctcaag gataacaac gattttcac gcaaaatgt 
      gccgacttt gacaaaagg ttagcagcg attttctcc 
      caggccttc gatgattgc tacaacctc gaaagcatc 
      ttcaaattt ctcgcaatc atcgggaat ttgctcgaa 
      aggtccgtt atcagagac gaaataact ccaaaatac 
      ccaagaatt attgacata ttcaacgag gaacttgat 
      acggtgaaa atcattttt gacgaaggc aaaaagaat 
      ggtattccc atcgataaa aatttcccc ccggtcgct 
      ggaaccctt atgtggata tctaaattg aggcaaagg 
      attgaaaaa ccaggcgat gatttgaaa ttattagaa 
      gatgatatt atcaagtcc gaggaggct catcattcg 
      tttgaaaaa tacgaccac atgatgcga attttggac 
      gatgagggc aaggaagtg tttggaaat tggtgcaag 
      tcaattccg caacaaatc gagactagt atggccaag 
      ttcgaactt atacgtaaa cctgagaac ttgattcat 
      ttgaatttt gatccggaa ttggtagcg gccttgcgg 
      gaaattcgg tacatgaag ttcttagaa attccggat 
      gtgcctcaa gaggcgtta gatctgttc gaaaaggtt 
      gaacttttg ttcgaatgt caacagaaa tttaacaga 
      gttgtgaat tggtataac catctcaag aagaacacg 
      cttaaggtg gaatacaac ttaattgag ccggaaatg 
      aaacaaata gatgagttg ctccaatca gtgcttgat 
      gctattacg tggagcact catgatgag gcaactctt 
      agtgccatt tatgaaaaa gttaaagat ctgtcggat 
      cgtgttgtg caatgtcag aagaatatg actgctatc 
      gaagccacg ctggatgcc tgggttgag gctccactg 
      tttgaaagg agagaaggc aaaaaagag aatctgcta 
      tatctcgaa gaccggtct gaacgtact actaaaaga 
      tttgctcaa attgagaat agccacgaa gaaataaaa 
      aaactccta gaagttaac tatcgattg ttctttaat 
      attcctgag ccggttgaa gaaccggtt gatgagtcg 
      tcgcctgaa gaagaagtt gctgagcca ccacccacc 
      ccaaaaaaa ggtaaaaaa gggaaaaag ccagtcgaa 
      acacccaaa gaaaaggag aaagagaaa gaaaaagaa 
      aaagggaag aaggagaaa ggtaagaaa ggtggaaaa 
      ggcaaaaag aagaagcaa aaagccctt gaagacgct 
      gaagctgag atgcaggaa gaacctgca gatccttac 
      gagaattat cgtaaagaa cactggagc aaatatttg 
      gaatatgtt gatcaacta gtcaaaaac aaacttgta 
      gctgcagtc cataatagt ttggtttac ttgctgaat 
      gagtctggc gatttagct cctattaca cctttgttt 
      gaactgtct ttagaactt catgatcct gacattgtg 
      tttcaacct tcgattaat ctaacagat gataataat 
      ttcgttgaa gaaataacc gaatgcgtg gaagatatt 
      ttcaaaatg ggtgaagtt atgaaacgg gtgaatccg 
      gaaagtgaa gaccagcat tacttttac gaagtcaaa 
      tcagataaa aatttggcc aaaatgact gaagagctt 
      ctgagcaga attatgttg atgagagaa gatgcgttt 
      gaatatctt aaagcattt gacgaattt acgcatatt 
      tggaccgac gataggcac gagtatttg cgccagttc 
      ctgcttttt ggccggttg ttgagtccc gaggagcac 
      gacagaatc gcggaacta aaagagacc ccaccgtct 
      gtgcaacag tttaaggag caaattgat ttttacgac 
      gatatgtac aaaaaggtc gaagctatg agcaatgaa 
      aagattctt gaaggtgac tggatgaaa attgatgtc 
      cggcccttg aaacaagct atccttaac acgatttgc 
      aaatggggc aatcttttc aagcagcat ctttacgat 
      cacgttatt actagcctc aatgatctc gacagtttc 
      attgtggag gcaattcaa gccatgcaa gtcacatta 
      gaggaggac gactacgac ggcttatta aaagtgatg 
      ggatatttg tttaaagtg aaggaaaga cagttggaa 
      accgataat atgttccag ccattgaag gaaatcatg 
      gatctgctg ttcgaatat gggatggaa tttccggaa 
      gacgtgcac gtccaatta caggagatt ccagacagg 
      tggcaacaa tgcaagaaa gttgccgca actactaaa 
      caaaacgtt gcaccactt caagccctt caagtgaat 
      gcgatcaaa agacgaatt aatttgttc gaaatccga 
      caagcgatg tatagagac atgtttaag aaacttccc 
      ttctttaac tggagctgt aaagatgtg tactctttg 
      ttagataaa actaatttc gaactgact gaacttgag 
      acagaaatg gcgaaattg caagagcaa gccaattta 
      ttcgaacta acgctgcct gagtttaaa ccaatgaat 
      caggcgagg aaggaaatt aggcaaatt aaacagttg 
      tgggactac gtccatatt ttccggtcg tgtatcgac 
      gaatggaag aaaaccccc tggaaaaaa attgacgtt 
      gaggcgatg gaaatggaa tgtaaaaaa ttcggcaag 
      gaggtgcga gccatggat aaggaatta aggggttgg 
      gatgtttac atccagctg gaagcggta ataaagaat 
      atgttaacg tcgttacga gccgtcacc gaattgcaa 
      aatccggcg attagggag aggcactgg aagcagttg 
      atgcaagct acgaaggtg aaatttgta atggacgat 
      tcgaccaca ctcagcgaa ttgctcgcc ttgaatttg 
      cacgagtat gaagatgaa gttaagaac attgttgat 
      aaatcagtc aaagaaatg gcgatggag aaagtccta 
      aaagaatta aacgcaacc tggactaac atgatgttt 
      gcgaccgaa gtccacgaa cgcacaaat ttgagactt 
      ttggtggct tccgaagag ttaattgag actcttgaa 
      gagaaccaa gttgctctc caaaacatg atgacgtcc 
      aaatttatc gatttcttc cttgaagag gtttccgac 
      tggcagaaa aaattatcg aatgctgat caagtcata 
      caagtgttt ttcgaagtg cagcgcaag tggtgctac 
      ttggaaagt attttcata gggtctgaa gacatcaga 
      agccaatta cctgaagat tcaagacgg tttgagaaa 
      atcgatagg gattttaaa gaggttttg tccgaaatg 
      ctgaaggat ttaaatgtg gtgaggtcc accaacaag 
      cccggactt tacgacaag cttgacggt attttgggg 
      caattaatt ttgtgcgaa aaagccctc aacgactat 
      ttggaaacg aaaagattg gcatttcct cgcttctac 
      ttcgtatcg tctgccgat ttattagat attttgtct 
      aacggaaat caaccagat ctcattcag agacatttg 
      accaaacta tttgattct ctggctaaa ctgaaattt 
      gaaaaagaa ggtgggaaa aattcaaag agagcctat 
      ggaatgatt tccaaagaa aatgaagaa catgtgcaa 
      ttcagccaa atttgtgac tgcactggc aaagtggaa 
      gtttggtta aatcgtgtt attgatgta atgagaaaa 
      acccttcaa agttgtttc gctgaggct atatcaacc 
      tacgatgaa aaacctaga gaggtttgg atttacgac 
      tatccagca caaccggca ctttgcggc acgcaaatt 
      tggtggaca actgaggta aacattgct ttcgcaaga 
      ctggaagaa ggttacgaa aacgcccta aaagactat 
      caaagaaaa caaatcaat cagttaaat gcccttatt 
      aatctcttg ttgggtgat ttgactgca ggcgagcgc 
      caaaagatc atgaccatt tgtaccatc gacgtgcac 
      tcgagagac gtagtcgcg aaaatgatt gcaatcaaa 
      gtggagaat tcacaagcc tttcagtgg caaagtcag 
      ttgcgacat cgctgggac gataaaatc aaagactgt 
      tttggtaat atctgtgac gcccagttc agataccaa 
      tacgaatat ttgggcaac accccccga ctggtgata 
      acaccctta actgatcgt tgctacata actctgact 
      caaagcttg catttaatt atgggggga gcacctgcc 
      gggcctgca ggaaccggg aaaactgag acaaccaaa 
      gatttgggg aaagcttta gggatgatg gtttacgtg 
      ttcaactgt tcggaacaa atggactat aagtctatt 
      gggaacatt tacaaaggg ttatcacag acgggttgt 
      tggggttgt tttgacgaa tttaaccga atttccatt 
      gaggtactg tctgtggta gccgtccag gtgaaagtc 
      atccaggac gctatcaag gacaagaaa gctaagttt 
      aatttcttg gggcaagat attgtctta gtccccacg 
      gtcggcctt ttcattacc atgaacccg ggctacgcc 
      ggccgtact gaactcccg gaaaatcta aaagcccta 
      ttcaggcca tgcgctatg gttgtgcct gacttcgcc 
      ctaatttgc gaaatcatg ttggtcgcc gaaggtttc 
      caagaggct cgtcttctg gcgcgcaaa ttcatcact 
      ctctacacg ttgtgtcgc gaattattg agcaaacaa 
      gaccattac gattggggt ttgagggct attaagtct 
      gttttggtc gttgcaggg tcgttgaaa cgtggcgat 
      agacaacgg ccggaagac caagtctta atgcgcgct 
      ttgcgtgat ttcaacatc cctaaaatc gttacagac 
      gatgtcccg gtttttatg ggactgata ggtgatttg 
      tttccggcc ttggacgtg ccgagaaag cgtgacccg 
      gactttgaa aaaacgata aaaaaatct gcggttgat 
      ttgaaattg caacctgag gacggtttc gtcttgaaa 
      gtggtgcaa ttggaggag cttttcgct gtgcgacat 
      tcagtattc gtgattggt aacacggga actggtaaa 
      actatggtt tggaagact ttgaacaag acttatcag 
      aaccagaaa agaaagccg atttataac gatattaat 
      cccaaagct gtgactaat gatgaattg tttggggtg 
      ataaacccg gccactaga gagtggaaa gatggtttg 
      ttttctgta atcatgaga gatcaggct aatttaacc 
      ggcgatggg cctaaatgg attgttctt gatggtgac 
      attgatccc atgtggatt gaatcatta aacacactt 
      atggatgat aataaagtg ctaactttg gccagcaat 
      gaacgaatt gctttaact tcagctatg cgattatta 
      tttgaaatt gcctcttta cgtactgca accccagcc 
      actgtttca agagccggt attttatac ataaacccg 
      gccgatctg ggttggaac ccttacgta gcttcctgg 
      attgatacc agaacccaa caaaatgaa aaagccaat 
      cttatgata ctctttgac aagtatgtt cctccttgt 
      ttggaaata cttcgtcac aaattgaaa aaaataaca 
      ccaatctct gaagtagcg catatttcg atgctttgc 
      ttcctcttg gactgtttc ctaacaccc cagaatgtc 
      cctcctgat tgtcccaaa gagtggtac gagatttac 
      ttcgtattt tgcacagtc tgggcgttt ggttcggct 
      ttgttccaa gaccaaatt gtcgactgg cgcaatgaa 
      tttagcaaa tggtttgtg aatgaattc aaaactatc 
      aaatttccc gtcactgga ggcaacgtc ttcagttat 
      tacgttgaa gaggaaact aaaaggttt gctccatgg 
      acggaacta gtacccgaa tttgagctt gatcccgat 
      attcccttg caagccact ttggtcaat acggccgaa 
      actaccagg attcggttt ttcatggat catttaatg 
      gaaaaacga attcctgtc atgttggta gggccggca 
      ggaagtggc aaaagtgtg attgttgcg gaaaaactc 
      accagctta tccgaacat tacgccgtt acaaatgtc 
      cctttcaat ttttacact acctctgaa atgttgcaa 
      agaattttg gaaaaaccc ttagaaaag aaagctggg 
      cgtgtgttt ggccctccg ggtaataag actatgatt 
      tatttcgtg gacgatatg aacatgccc gaagttgac 
      aagtatttt actgtacaa cctcacacg ttaattcgc 
      cagtatatg gactaccag cattggtat gaccgtcag 
      aaactgact ttaaaggac attcacaat gttcagttt 
      gtctcctgc atgaaccca accgccggc tctttcacc 
      ataaaccca cggttgcag agacacttt tgcgtcttt 
      gccgtgagt tttccgagc caagaggcg tcgaaccat 
      atctattac agtattata tcgcaacat tttgagtcg 
      gaacataac aggtttggc aaaaatatt ttcaaactg 
      agtgcttct ctagtggat gcggcggtt tttctgcac 
      cagaaagta gcggctagt tttctgcca accgctgtc 
      aagtttcat tacacattt actttgcga gacctttcg 
      aatattttt caaggaatg cttttcacg accggagac 
      gctattaaa actcagacc gatttgatc cggctttgg 
      atgcacgaa tgtggccgc gtttacggt gacaaactg 
      gtcgaaaaa cgcgatttg gacacttac aaaaagctg 
      gtaattgag tcagtgaag aaaagtttc gaggagttg 
      gacgaaaat gaggtgttt gaggaacct ttgatttat 
      tgtcatttt gctgagggc atgggggat ccgaaatac 
      ttccccatt catgaattt gaccatttg agtaaactc 
      ttgcacgaa gctttggcc ggttataat gatctagtg 
      gcggcgatg aatttggtt ttgtttgaa gatgcaatg 
      tatcacatt tgccgcatt aacagaatt atggaagct 
      ccaagaggt aacgcgctg ctcattgga gttggaggt 
      tcaggaaag cagtctttg acgagactt gcttccttc 
      atctcctcg tttgaagtg tttcaagtc cagttgaag 
      aaaggttac tctatgact gacctaaag gccgatttg 
      gcccaatta tatctaaaa gcgggtttg aagagcgtt 
      ggaattgtg tttctgatg actgatgcc caagtccct 
      caagagatt ttcctggtt gcgattaac gatatgttg 
      gcatcgggc gaaatcagt gagttactg cccgacgaa 
      gacgttgaa aatgttatc aatgcagtt agaggtgag 
      gtgaagcaa agtgggtta caagacaca cgggagaat 
      tgttggaaa tttttcatt gatcgtgtc cggagatta 
      ttaaaaacg gtgttgtgt ttctcacca gttggttcg 
      actctacga gtgcgagcg agaaaattt ccggctctt 
      gttaactgt acttctatc gactggttc catgaatgg 
      ccgagggaa gccctggaa tcagtatca aagagattt 
      ttggcggaa attgaagtt ctccccaaa gatttagtt 
      ccttcagtt tccaacttc atgtcagat gttcacgga 
      gtggtgaac accatgtcc gagttgtat ctacaaaat 
      gagaaacgc tacaactac accactcct aaatctttc 
      ctagaacag atcgccttg tattctaaa cttctttac 
      gaaaagact aaaaatttg gaggacaat atcgaacgc 
      ctcgagtct ggtttactc aaactggca tcaacttcg 
      gaagaagtg gacggtttg aaagaagtg ttggcagtc 
      caagaggta gaattgaat gaaaagaat gaagccgcc 
      ggtaaactc attgccgtc ctaagtgcc gaaaacgaa 
      aaagttgca aaagaacag gcaatcgct agcgaggaa 
      gaagccaaa gttaaacta atcgaggag gatgttagt 
      gtcaaacaa aaaatctgt gccgatgat ttggccaaa 
      gccgagcca gcgctaatc gcagcccaa caagcttta 
      aacaccctg aataaaaac aacttaact gaactgaaa 
      tccttcacg caaccgcct gaagcggta gtcgctgta 
      acagccgct gttttaatc ctgttttcg ccaaaagga 
      cgaattccg aaagatcgt agctggaaa gcttgtaag 
      gggttgatg acaaaagtc gataaattt ttagaagat 
      ttaataaac tatgataag gaaaacatg caaccggaa 
      gtagtgaaa gcaactctg gaatatacg aaaaatccc 
      gagttcaat ccagaaaaa attttgagc aagtcggtg 
      gcagctgct ggattgtgt gcgtgggtc attaatatt 
      ttgaaattt tacgacgtg tttgtcgtg gtcgaaccc 
      aagaggaaa gctttgcaa aaagccaat caggaactg 
      gcagatgcg agagctaaa ctggccgag cttaacgag 
      aaattgaat tatctcgag tcacaattg gcgattttg 
      aaggccgat tttgaggaa gctacagcc gcgaagatg 
      aaatgtcag gccgaagct gatgctacg actcaaatg 
      atcgattta gctaatcga cttgttaat ggtttggcg 
      tcggaaaat atcaggtgg cgagagttg gtcaagttg 
      taccggaaa atgataatt acactgcca ggggatgtg 
      ttgatgata acttgcttt atttcgtac gttggatgc 
      ttcacgaga cggtacaga accgagatg gttgaacat 
      cactggata ccctcgctg aaaaaaatc gagccgaaa 
      attccgatg agtgaaggg ctggatccc ttatccctg 
      ctcacagac gatgcaatg gtcgcagga tggaataat 
      gaggggctt cctaatgat cgtatgtca accgagaat 
      gcttgtatt ttaacaaat tcggcaaga tggcccctg 
      atgattgat ccccaattg caaggagtt aagtggatc 
      aaaactaaa tacggcgat agcttgaca gttattcga 
      ctgagcatg aaaaattac ttggacact attgaaaga 
      tgtatccaa aatggtgaa attatcctt gttgaaaac 
      ataggcgag accgtggac gcggtctta gaccctgtt 
      ctgggtcga gtcttagtc aaaaaaggc aaggcgata 
      aaaatcggt gataaggaa gtggattac aaccccaac 
      tttaggatg atcatgcac acgaaactg gcaaatccg 
      cattacaaa ccggaaatt caagcacaa actaccctc 
      atcaacttc acagtaacg cgagatggt ttagaggag 
      cagcttttg gcagaagtc gtcaaagct gaacgccca 
      gacttggaa agtttgaaa gcgaattta acgaaacaa 
      caaaacgat ttcaaaatt attttgaaa agatgtgag 
      gataattta ttgtttaga ctttcctcg gccacgggt 
      aacatactg ggcgatgtg gaactagtc gagaatttg 
      gaaacaacc aagaaaatg tccacggaa attgaagag 
      aaagtcaaa gaagctaaa ataacttca gtcaaaatc 
      gacgaagcg cgtgaacag taccgacca tgttcggct 
      agagcttcg ctcctttat ttcattttg aacgatctt 
      tgccgcatc aacgcaatc tatcaattc tcattgaag 
      gccttcagt gtggtgttt aaggacgcg ttatctaaa 
      gcagtaccg gccgaaaag ttaaaagat cgggtagtt 
      aacttattg gacagtata actttttcg gtatttatg 
      tacacaact cgaggtctg ttcgaatgt gacaagttg 
      attttcatg gcccaaatg gcatttcaa attttgctg 
      catgctaaa gaaatcgat cacgctgaa cttgacttt 
      ctgttacgg taccctgta gtaccgaac ttgacaacc 
      cctgtggac ttcctcaca aatcagtcc tggggcggc 
      attaaagcc ctgtcagag tttgacgat ttcagaggt 
      ttagacaaa gacttggaa ggctcggcg aaacgttgg 
      cgaaaattc gtcgatagt gaatgcccc gaaaaagaa 
      aagttcccc ggcgagtgg aaaaacaaa accgctttg 
      caacacttg tgcatgatg cgtgccctc cgccccgac 
      cgtatgacc tacgctgtt cgttgtttc attgaagag 
      aaactcgga gccaaatac ataacagcc agatccgtc 
      gaatttgca aaatcttac gaagaaaca agctcttca 
      acccccgtg ttctttatt ctatcgcca ggcgtaaat 
      ccgctcaag gatgtagaa aagctgggc aaaaagctg 
      ggtttcacc tttgattct ggtaacttc cacagtatt 
      tccttgggc caaggccag gaaatcgtg gctgaaaac 
      gcaatggat ttggcgtcg gagcggggc gattgggtc 
      attttgcaa aacattcat ttagtcgag cggtggttg 
      tccactttg gagaaaaaa atggaacaa tgcgccgaa 
      agcgcccat caaaagttt aggttgtat ttgagcgct 
      gagcctaac gctgatccc caagtgtcc gtaatcccg 
      caagggatt ctagaatcg tcgatcaaa atcacaaac 
      gagccgccg actggcatg tatgccaat ttacacaaa 
      gctttggac aatttcagc caggaaacg ttagacatg 
      tgcacgaaa gaagcggag tttaagctg attttgttc 
      gctttgtgc tatttccat gccgtggtt gccgaaaga 
      cggaaattt gggccacaa gggtggaac aggaattac 
      ccctttaat gttggcgat ctcacaatt agcgtaaac 
      gtgttgtac aattatctg gaaagtaac agtaaggtc 
      ccctacgaa gatttgcgc tatctgttt ggggaaata 
      atgtacggg gggcatatt acggacgat tgggatcga 
      cggttgtgc cgaaattat ctaatggag tatctccag 
      cccgaattg ctggaagga gacttgcag tttgcgccg 
      ggatttttt gccccacct aatacagac tatgttggg 
      tatcatcgc tatattgac gaccgtttg ccgcctgaa 
      agcccctac ctttacggc ctacaccca aacgcggaa 
      attggcttc ttggcctac acttctgaa gttatgttt 
      agaacaatt ttcgaaatg caaccgcga gatgcggga 
      gcttcggta ggccatgga ttttctcga gaggataag 
      gttaaatca acccttgaa gatatccaa gaccggctc 
      cccgaggag tttccggtc gccgaaatg atggcaaaa 
      gtcgaagac aggaccccg tacataatt gtggcgttc 
      caggagtgt gacagaatg aacagttta acacgggag 
      atgaagaga tcgcttcgg gagctcgac ttgggatta 
      aagggtgaa cttacgatt acgtcggac atggaggtg 
      ttggaagag gccctattt atggaccaa gtccctgac 
      tcgtggtcc gtaaaggcc taccccagc atgctgcct 
      ttgggtcag tgggtggcc gacttgggg gctagaatt 
      aaggagctg gaggggtgg gttaccgat ttctcgatg 
      cctcccacc gtctggctg gggggtttc ttcaacccc 
      cagtcgttc ctcactgcc attatgcaa caaacggct 
      cgcaaaaac gaatggcct ttggacaaa atgtgtctg 
      ttgaccgac gtcaccaaa aagcagaaa gaggagttc 
      ggggcggct cctcgggaa ggcgcatat gtgcacggt 
      ttatttatg gagggcgca aggtgggat acgcagctc 
      ggaagtatt gccgatgct aagcttaaa gaattgttc 
      cctgtaatg ccggttata ttcatcaag gcaatcacg 
      caggataag caggattta cggaatatg tacgactgt 
      cctgtttac aaaacaagg actcgggga ccgactttc 
      gtctggact tttaattta aaaacgaag gagaaggcg 
      tccaagtgg acccttgca ggagtagcg attctgtta 
      cagatttaa ttatttatt ttattgtag ctgttaata 
      aaattttat tttaatt
    The data is licensed under a Creative Commons Attribution 3.0 Unported License. (CC-BY) CC-BY