Status
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Gene information
General information
TC006755 Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007423.3: 13775020..13784272
Sequence information
Transcripts / Proteins (1) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    		TC006755
    Gene ontology

    GO terms for Tribolium

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      Status: {{ goTerm.status }}
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    There are no GO terms for Tribolium at the moment. You can help the community by providing some GO terms for this gene.


    GO terms for the homologous Drosophila genes

    Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term - use "graph views" to browse related terms ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.


    Gene
    {{ goGene }}
    The Tribolium gene the GO term is assigned to.
    GO ID *
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    The ID of the GO term you assign to the gene. Please enter only the ID of the GO term with proceeding 'GO:'. This information is mandatory.
    Evidence
    {{ blurEvidenceResult }}
    The evidence code describes with which method the function or location, expressed by the GO term, was show for this gene. Please refer to this page for a definition of the evidence code and a decision tree.
    Reference *
    {{ blurReferenceResult }}
    The reference where the function or location is described for the gene. Please enter a PubMed ID. This information is mandatory.
    Quotation
    If you paste here the relevant section of the reference it is for us a great help to review your annotation. The quotation may be also be displayed to the users of iBeetle-Base.
    Name
    You may enter your name. The contact information can help us to clarify any questions. If you agree, we may show your name on this page to honor your contribution.
    Email
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    Publish name
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    * : mandatory fields
    For help on how to submit larger datasets or non experimental data please contact us.
    iBeetle screen iB_01087

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 0.0% (includes death as pupa, adult)

    Analysis of embryonic musculature and early development
    number of eggs/embryos/larvae on slide: > 50 embryo/egg with embryonic tissue, no cuticle, no fluorescence - Penetrance (percentage of animals/eggs on slide): more than 80%

    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    Analysis of larval stage 1 cuticle
    number of eggs/embryos/larvae on slide: > 50
     egg without cuticle embryo/egg without visible larval cuticle in cuticle preparation - Penetrance (percentage of animals/eggs on slide): more than 80%
    affected eggs/embryos/larvae - Penetrance (percentage of animals/eggs on slide): more than 80%
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 40.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 100.0% (includes death as larva, prepupa, pupa, adult)

    larva lethality early (L5/6) - Number of animals showing the phenotype: 3 (11 dpi)
    Days post injection

    pupal molt not fulfilled (died as pupa) - Number of animals showing the phenotype: 1 (16 dpi)
    Days post injection

    eclosion not fulfilled (with pupal and adult features) - Number of animals showing the phenotype: 3 (16 dpi)
    Days post injection


    Pupal morphology
    wings slightly shortened - Number of animals showing the phenotype: 4

    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC006755 RA
      MSKDKTFQE RLKNIFKKK PDLVNVPPN REFILTDEL 
LRDLGKDAP THTRVKAMK ELAPHLAKL EPNGVEKLW 
SCIQDMFLR EYPNDVRHA TFGFLQSVI RSQFERIDV 
MRAQFFRFI KHHDNPQDV AHRVDLLAA LTNDGKEVE 
HFEEEIGPF LLNWITDVS RVGKLHEFL KILDNVIKF 
NSPHLDEYT MTGYVKHIC VLCCNTNQF PIVILCLQI 
LGTVVAYSI LPPESLSQF VGTLCRTVN IKCYCPASW 
KTMKNLLGT HLGHSTLFT MCRFLQEPN LKHDAGLMR 
GCVFYIHMA LWDINSMQN LCCPPSSVL PSVLQAVRC 
NHPSVAYEV ILGIQKLIN KQGLDLLEP TWDIILEII 
LHIVKQVEL APNEVPNSS TALTLHEIL NTIENLIEV 
GNYKGSMNQ FFAVIHECS RDRPETSVL KLIKYQSKN 
IRPTESAWL QNLFNLLSN YFKPEVRTN IRLKVLNVL 
EDTIRLYGL YEDELINHI VIPHMQNIA QDDNVVVRS 
EVAKLLVDL CKNYNSNIC TELLEILEK LLQRPPNAN 
NESDFLDVG VLVPGLVQV FARKIHKLP SSHAVLIYK 
IFVNFLERN LLKPPFKEF NQSRLMIFD CLLNMRADS 
YCRLGLPDP DTKQMKYSP YLCVSYKPN EPIVTSPPT 
TSPSQTPVC KVTFLAIES AFKLLLNYL ENEKDWEIL 
KLVMEKLPK MLGNKAIVL TKSGNPDLN NLVDVLCTM 
LQNRSLNLS EVKVTRLEF QTAVVSVMV ALSSYGNSL 
DQYHQQLLI NTLTRSTGT DPRCSRQSI NSLTICMVD 
MRETMMKLL PDVLLRLSK ISATKYIAM PVLEFLSTL 
SQLPNVYAN FVGDQYMAV FAIALPYTN PFKYDNYIV 
SLAYHVISV WFLKCRLPF RRDFVKFIV SGLQTNVMV 
PFQELSQFK LSLSSMNQD SSDRKRSSS LTEQGSRRR 
VKPDPVKKS PFIQKTTPR DKTVLTFYE ELNETCIDL 
MARYTYSPC SALPSRLPT AEFLLNGGI SKSWMLGNK 
LITITTSGC TERVLKHGV CDKCWSLCS SHNNSKIAR 
YARSNSGNE EKESFLTRQ GSSEEGKRY DSANLPKLI 
GGDDRREAL VCACWCQGW AEVLIRRPT GNVSWVMKV 
QNQVSFKQH IFEFPLNEM STLYMPDLF FEPSSAISI 
EEQEETEEF EEAVASSSS RPVSVPGSP TKQSLSRQS 
SRDSADDEL EFVYDDGTK SRNPVRRSN SSPEMANWK 
NPFVHQKIE NDSGNPDKK DVRVSCEAI PEEISGLGT 
SPPTGEPPK QEHPSLLTC YSYPGSSPP GESGIAPKP 
YKTVPASPN QINSQSQPT FVQETNVLD RPNNLPNLT 
NLAPLTTKP PQSPTQTSP RLQRHADKE KDGTSIQKS 
SSSSKIEKN RAKAPDPSL AEKRDRLHT ISVMSTSTR 
KPTPPKKIP KEILKSGLN PSFVFLQLY HTACFGSTS 
EVPLYVPSC TVIDRAIGI LDRMYPYEV HKIGVLYIN 
EGQVEKEAE ILRNTCGCV RYMEFLQNL GTLIRLADV 
NPRDIYLGG VDQGGADGK YMYTHQDDL VMLAFHVAT 
LMPNKDSDP NGNYKKAHV GNDNVVIVY NNSGQEFDI 
STFRSQVTL AYIIVEPLD YQCNKVEVK VKSDLLKII 
GSNEVIVVS DQSVSILVR QLAIHADLA ATVLNSLRS 
HATDPYASN WLERLRKLK NLREKVVQE NNKRKEAQK 
GFSEEKDIV EDFTDFT
    CDS sequence
    • >TC006755 RA
      atgagcaaa gacaagacg tttcaagag cgcctgaag 
aacatcttc aagaagaag ccagattta gtcaatgtg 
cccccaaac cgcgagttt atcctaacc gatgagctg 
ctgcgcgac ctggggaag gacgccccc acccacacg 
cgcgtcaaa gccatgaag gagctggcc ccgcatttg 
gccaagctc gagccgaac ggggtggag aagttgtgg 
agttgcatt caggacatg ttcctgcgg gagtacccc 
aacgatgtg cggcatgcc acctttggg tttctccag 
agcgtgatt cggagccag tttgagagg attgatgtg 
atgagggcg cagtttttt cgctttatt aagcaccat 
gataacccc caggatgtg gctcatagg gtggatctt 
ttggccgct ttgaccaat gacgggaag gaagtggag 
cactttgag gaggaaatt gggccgttt ctgctcaat 
tggatcacg gatgtgagt cgggtgggg aagttgcac 
gaatttttg aaaattttg gataatgtg atcaagttt 
aattcgccg catttggac gagtacaca atgaccggc 
tacgtcaaa cacatttgc gtcttgtgc tgcaacacc 
aatcaattc ccgatcgtt attctgtgc ttacaaatt 
ttgggcacc gttgtggct tacagtatt ttacctcca 
gagtcatta tcacaattt gtgggtact ttatgtcgc 
actgtaaac atcaaatgt tactgtccc gcgagttgg 
aagaccatg aaaaacttg cttgggacc catttgggt 
cattcgacc ctattcaca atgtgccgt tttttgcaa 
gaaccgaac ttaaaacac gatgctggg cttatgaga 
ggctgcgtt ttttacata catatggca ctgtgggac 
attaattcg atgcaaaat ctttgttgc ccccctagc 
tctgtccta ccctcagtt ttacaagcg gttcggtgt 
aaccaccca tcagtggcg tacgaagtg attttaggg 
atccaaaaa ttgataaat aaacaagga ttggattta 
ttggagccc acgtgggac ataatcctt gaaataatc 
ctacacata gtcaaacaa gtcgaattg gccccaaat 
gaagttcct aacagctca acagcactg acattgcac 
gaaattttg aacacaatc gagaatcta atcgaagtt 
ggcaattac aagggttca atgaaccag ttttttgca 
gtcattcat gaatgttca cgtgatcga cccgaaaca 
agcgtctta aaactaatc aaataccag tcgaaaaat 
atcagaccg actgaaagt gcctggtta cagaaccta 
ttcaattta cttagcaat tatttcaag cccgaagtt 
cgcactaac atacgcttg aaagtcctg aacgtgctt 
gaggacacg atacgactt tacggtctc tacgaggac 
gagctaatc aaccacatt gtcatccca cacatgcaa 
aatatcgcc caagacgac aatgtcgtg gtccgatct 
gaagtagcg aagcttttg gttgatttg tgcaaaaac 
tacaacagt aacatttgc accgaactg ctcgaaatc 
ctcgaaaag ctactccaa cgcccaccg aacgcaaac 
aacgaatcg gatttcctg gacgttgga gtcctcgtc 
ccgggattg gtccaagtc ttcgcgcgc aaaatccac 
aaattaccg tcaagccac gccgtcttg atttacaaa 
attttcgtc aacttcctc gaacgcaat ttactcaaa 
ccgccgttt aaggaattt aatcaaagt cggctcatg 
attttcgat tgtttgtta aatatgcgg gctgatagt 
tactgtcgc ctcgggcta cctgatccc gatacgaaa 
caaatgaag tacagtccg tatttgtgc gtgagttac 
aagccgaac gaaccgatt gttacgtca ccgccgact 
acgtcgccc agtcaaacg ccagtttgt aaagtgacg 
tttctcgca atcgagagt gcctttaaa ttgttgttg 
aattatttg gaaaatgag aaagattgg gaaattttg 
aagcttgtt atggaaaaa ttgccgaaa atgttgggc 
aataaagcg atcgttttg acaaaaagt ggtaatccg 
gacctgaac aaccttgtc gatgttttg tgtaccatg 
ttacaaaac cgttcgctg aacttaagc gaagtcaaa 
gtgactcgt ttggagttt caaaccgcc gtggtgtca 
gtcatggtg gcactgtcg tcctatgga aacagtctc 
gaccagtac caccaacag ttgctgata aatacccta 
actcgaagc accggcacc gacccacgt tgttcccgc 
cagtcgata aattcccta acaatttgt atggtcgac 
atgcgtgaa acaatgatg aaactacta cctgacgtt 
ctcctacgt ctatcaaaa atatccgca actaaatac 
atcgcaatg ccggtgttg gaatttcta tcaactcta 
tcgcagtta cctaacgtt tacgcgaat tttgtcggc 
gaccaatac atggccgtc tttgctatt gcgctcccg 
tacactaac ccgttcaaa tatgacaat tatatcgtc 
tcattagcc tatcacgtg atttcggtt tggttccta 
aagtgtcgt ctgccgttt cggcgcgat tttgtcaag 
tttatagtg agcggtctg caaacaaac gtcatggtt 
ccgtttcaa gaattaagt caatttaag ttgagctta 
agtagcatg aatcaggac agctctgac cggaagcgc 
agctcgagt ctcaccgaa cagggctcc agacgccgc 
gttaagccc gaccctgtc aaaaagagc ccctttatc 
cagaaaaca accccgaga gacaagact gttttaacg 
ttctacgag gaattgaac gagacttgt attgattta 
atggcccgg tacacatat tccccgtgt agtgctctg 
ccctcgcga ctccccacc gctgagttt ttgctaaat 
gggggcatt tccaagtcg tggatgttg ggcaataaa 
ttgattacg attacgacg agtggttgc accgaacgt 
gtgttaaaa cacggcgtt tgtgataag tgttggtcg 
ttgtgcagt tcgcataat aatagcaaa attgcgaga 
tatgcaagg agcaatagt gggaatgag gagaaagag 
tcgtttctg acgcgacaa ggttcgagt gaggagggg 
aaaaggtac gattcggcc aatctaccg aagctgatt 
ggcggagat gacaggagg gaggcgcta gtgtgcgcg 
tgctggtgt caggggtgg gccgaagtg ttgatcagg 
aggcccacg ggcaacgtg tcctgggtg atgaaggtc 
cagaaccag gtctcgttc aagcagcac attttcgaa 
ttccccctc aacgaaatg tccactctc tacatgccc 
gacctgttc ttcgagcca agctcagcc atctcgatc 
gaagaacag gaagaaacg gaagaattt gaagaagct 
gtagcttca tcaagcagt cgtccggtc agcgtacca 
ggctcaccc accaaacag tctctatct aggcaaagt 
tcgcgcgat agcgccgac gacgaacta gaattcgtg 
tacgacgac ggaacaaaa tcacgaaat cccgtccgt 
cgttcgaat tctagtccc gaaatggca aactggaaa 
aatcccttc gtgcatcaa aaaatcgaa aacgactcg 
gggaatccc gacaagaag gacgtcaga gtgagctgt 
gaggcgatt ccggaggag atttccggt ttagggaca 
agtccgccg actggagag cccccgaaa caggaacac 
ccctcactt ctcacgtgt tacagttat ccggggtct 
tcgccccct ggtgaaagt ggcatagcc cctaaaccc 
tacaaaacg gtcccggcg tcccccaat caaatcaat 
tcccagtca cagccgact tttgtacaa gaaacgaac 
gtccttgac cgacctaat aatttaccc aacttgact 
aatctagcc cccttgacc accaaaccg ccccagagc 
cccactcag acctcgccc cgactgcag cggcacgcc 
gacaaagaa aaagacgga acctcgatt cagaagagc 
tcgtcttcg tccaagatc gagaaaaat cgtgcgaaa 
gcgccggac ccgagtttg gccgaaaag cgcgatcgg 
ttgcacacg atctcggtc atgagcaca tcgacccga 
aaaccaaca ccaccgaaa aaaatccct aaggaaata 
ctcaaaagt ggtttaaac cctagtttt gttttcctc 
caattgtac cacactgcg tgctttggt agcacttcc 
gaagtgcca ctttacgta ccctcgtgt actgttatc 
gaccgagcg atcggtatt ttagatcgg atgtatccg 
tacgaagtg cacaaaatc ggggtcttg tacattaat 
gaaggccaa gtcgaaaag gaggccgaa attttgcgc 
aatacgtgt gggtgtgtc cgctatatg gagttcttg 
cagaacttg ggcactttg attcgattg gccgacgtt 
aacccacgt gatatttat ctagggggc gtggaccag 
ggcggggcc gacggcaag tacatgtac acgcatcag 
gacgatttg gttatgttg gcgtttcat gtggcgact 
ttgatgccg aataaagat agcgacccg aatggaaat 
tacaaaaag gcgcacgtt ggcaacgat aacgttgtc 
attgtgtac aacaacagt gggcaagag tttgacatt 
agtacgttt aggagtcag gtgactttg gcgtacatc 
atcgtggag ccactcgat tatcagtgc aataaagtc 
gaggtcaag gtcaagtca gacttgttg aaaatcatt 
ggatcaaac gaggttata gttgtttcg gaccaaagt 
gtgtcaatt ttagtgagg caacttgcc atacatgcc 
gatttggca gcgactgtt ctcaattcg ctacggagt 
cacgcgact gatccgtac gcctctaat tggctggaa 
agactgagg aaattgaaa aatttgaga gagaaggtc 
gtacaagag aacaataag aggaaagag gcgcagaaa 
ggcttcagc gaggaaaag gacatcgtg gaggatttt 
accgacttt acataa
    mRNA sequence
    • >TC006755 RA
      ttacaaaaa ctaggttat atcggaaat tttcaaacc 
gacgaaaat gtaacaagt tcgcgacaa aatgagcaa 
agacaagac gtttcaaga gcgcctgaa gaacatctt 
caagaagaa gccagattt agtcaatgt gcccccaaa 
ccgcgagtt tatcctaac cgatgagct gctgcgcga 
cctggggaa ggacgcccc cacccacac gcgcgtcaa 
agccatgaa ggagctggc cccgcattt ggccaagct 
cgagccgaa cggggtgga gaagttgtg gagttgcat 
tcaggacat gttcctgcg ggagtaccc caacgatgt 
gcggcatgc cacctttgg gtttctcca gagcgtgat 
tcggagcca gtttgagag gattgatgt gatgagggc 
gcagttttt tcgctttat taagcacca tgataaccc 
ccaggatgt ggctcatag ggtggatct tttggccgc 
tttgaccaa tgacgggaa ggaagtgga gcactttga 
ggaggaaat tgggccgtt tctgctcaa ttggatcac 
ggatgtgag tcgggtggg gaagttgca cgaattttt 
gaaaatttt ggataatgt gatcaagtt taattcgcc 
gcatttgga cgagtacac aatgaccgg ctacgtcaa 
acacatttg cgtcttgtg ctgcaacac caatcaatt 
cccgatcgt tattctgtg cttacaaat tttgggcac 
cgttgtggc ttacagtat tttacctcc agagtcatt 
atcacaatt tgtgggtac tttatgtcg cactgtaaa 
catcaaatg ttactgtcc cgcgagttg gaagaccat 
gaaaaactt gcttgggac ccatttggg tcattcgac 
cctattcac aatgtgccg ttttttgca agaaccgaa 
cttaaaaca cgatgctgg gcttatgag aggctgcgt 
tttttacat acatatggc actgtggga cattaattc 
gatgcaaaa tctttgttg cccccctag ctctgtcct 
accctcagt tttacaagc ggttcggtg taaccaccc 
atcagtggc gtacgaagt gattttagg gatccaaaa 
attgataaa taaacaagg attggattt attggagcc 
cacgtggga cataatcct tgaaataat cctacacat 
agtcaaaca agtcgaatt ggccccaaa tgaagttcc 
taacagctc aacagcact gacattgca cgaaatttt 
gaacacaat cgagaatct aatcgaagt tggcaatta 
caagggttc aatgaacca gttttttgc agtcattca 
tgaatgttc acgtgatcg acccgaaac aagcgtctt 
aaaactaat caaatacca gtcgaaaaa tatcagacc 
gactgaaag tgcctggtt acagaacct attcaattt 
acttagcaa ttatttcaa gcccgaagt tcgcactaa 
catacgctt gaaagtcct gaacgtgct tgaggacac 
gatacgact ttacggtct ctacgagga cgagctaat 
caaccacat tgtcatccc acacatgca aaatatcgc 
ccaagacga caatgtcgt ggtccgatc tgaagtagc 
gaagctttt ggttgattt gtgcaaaaa ctacaacag 
taacatttg caccgaact gctcgaaat cctcgaaaa 
gctactcca acgcccacc gaacgcaaa caacgaatc 
ggatttcct ggacgttgg agtcctcgt cccgggatt 
ggtccaagt cttcgcgcg caaaatcca caaattacc 
gtcaagcca cgccgtctt gatttacaa aattttcgt 
caacttcct cgaacgcaa tttactcaa accgccgtt 
taaggaatt taatcaaag tcggctcat gattttcga 
ttgtttgtt aaatatgcg ggctgatag ttactgtcg 
cctcgggct acctgatcc cgatacgaa acaaatgaa 
gtacagtcc gtatttgtg cgtgagtta caagccgaa 
cgaaccgat tgttacgtc accgccgac tacgtcgcc 
cagtcaaac gccagtttg taaagtgac gtttctcgc 
aatcgagag tgcctttaa attgttgtt gaattattt 
ggaaaatga gaaagattg ggaaatttt gaagcttgt 
tatggaaaa attgccgaa aatgttggg caataaagc 
gatcgtttt gacaaaaag tggtaatcc ggacctgaa 
caaccttgt cgatgtttt gtgtaccat gttacaaaa 
ccgttcgct gaacttaag cgaagtcaa agtgactcg 
tttggagtt tcaaaccgc cgtggtgtc agtcatggt 
ggcactgtc gtcctatgg aaacagtct cgaccagta 
ccaccaaca gttgctgat aaataccct aactcgaag 
caccggcac cgacccacg ttgttcccg ccagtcgat 
aaattccct aacaatttg tatggtcga catgcgtga 
aacaatgat gaaactact acctgacgt tctcctacg 
tctatcaaa aatatccgc aactaaata catcgcaat 
gccggtgtt ggaatttct atcaactct atcgcagtt 
acctaacgt ttacgcgaa ttttgtcgg cgaccaata 
catggccgt ctttgctat tgcgctccc gtacactaa 
cccgttcaa atatgacaa ttatatcgt ctcattagc 
ctatcacgt gatttcggt ttggttcct aaagtgtcg 
tctgccgtt tcggcgcga ttttgtcaa gtttatagt 
gagcggtct gcaaacaaa cgtcatggt tccgtttca 
agaattaag tcaatttaa gttgagctt aagtagcat 
gaatcagga cagctctga ccggaagcg cagctcgag 
tctcaccga acagggctc cagacgccg cgttaagcc 
cgaccctgt caaaaagag cccctttat ccagaaaac 
aaccccgag agacaagac tgttttaac gttctacga 
ggaattgaa cgagacttg tattgattt aatggcccg 
gtacacata ttccccgtg tagtgctct gccctcgcg 
actccccac cgctgagtt tttgctaaa tgggggcat 
ttccaagtc gtggatgtt gggcaataa attgattac 
gattacgac gagtggttg caccgaacg tgtgttaaa 
acacggcgt ttgtgataa gtgttggtc gttgtgcag 
ttcgcataa taatagcaa aattgcgag atatgcaag 
gagcaatag tgggaatga ggagaaaga gtcgtttct 
gacgcgaca aggttcgag tgaggaggg gaaaaggta 
cgattcggc caatctacc gaagctgat tggcggaga 
tgacaggag ggaggcgct agtgtgcgc gtgctggtg 
tcaggggtg ggccgaagt gttgatcag gaggcccac 
gggcaacgt gtcctgggt gatgaaggt ccagaacca 
ggtctcgtt caagcagca cattttcga attccccct 
caacgaaat gtccactct ctacatgcc cgacctgtt 
cttcgagcc aagctcagc catctcgat cgaagaaca 
ggaagaaac ggaagaatt tgaagaagc tgtagcttc 
atcaagcag tcgtccggt cagcgtacc aggctcacc 
caccaaaca gtctctatc taggcaaag ttcgcgcga 
tagcgccga cgacgaact agaattcgt gtacgacga 
cggaacaaa atcacgaaa tcccgtccg tcgttcgaa 
ttctagtcc cgaaatggc aaactggaa aaatccctt 
cgtgcatca aaaaatcga aaacgactc ggggaatcc 
cgacaagaa ggacgtcag agtgagctg tgaggcgat 
tccggagga gatttccgg tttagggac aagtccgcc 
gactggaga gcccccgaa acaggaaca cccctcact 
tctcacgtg ttacagtta tccggggtc ttcgccccc 
tggtgaaag tggcatagc ccctaaacc ctacaaaac 
ggtcccggc gtcccccaa tcaaatcaa ttcccagtc 
acagccgac ttttgtaca agaaacgaa cgtccttga 
ccgacctaa taatttacc caacttgac taatctagc 
ccccttgac caccaaacc gccccagag ccccactca 
gacctcgcc ccgactgca gcggcacgc cgacaaaga 
aaaagacgg aacctcgat tcagaagag ctcgtcttc 
gtccaagat cgagaaaaa tcgtgcgaa agcgccgga 
cccgagttt ggccgaaaa gcgcgatcg gttgcacac 
gatctcggt catgagcac atcgacccg aaaaccaac 
accaccgaa aaaaatccc taaggaaat actcaaaag 
tggtttaaa ccctagttt tgttttcct ccaattgta 
ccacactgc gtgctttgg tagcacttc cgaagtgcc 
actttacgt accctcgtg tactgttat cgaccgagc 
gatcggtat tttagatcg gatgtatcc gtacgaagt 
gcacaaaat cggggtctt gtacattaa tgaaggcca 
agtcgaaaa ggaggccga aattttgcg caatacgtg 
tgggtgtgt ccgctatat ggagttctt gcagaactt 
gggcacttt gattcgatt ggccgacgt taacccacg 
tgatattta tctaggggg cgtggacca gggcggggc 
cgacggcaa gtacatgta cacgcatca ggacgattt 
ggttatgtt ggcgtttca tgtggcgac tttgatgcc 
gaataaaga tagcgaccc gaatggaaa ttacaaaaa 
ggcgcacgt tggcaacga taacgttgt cattgtgta 
caacaacag tgggcaaga gtttgacat tagtacgtt 
taggagtca ggtgacttt ggcgtacat catcgtgga 
gccactcga ttatcagtg caataaagt cgaggtcaa 
ggtcaagtc agacttgtt gaaaatcat tggatcaaa 
cgaggttat agttgtttc ggaccaaag tgtgtcaat 
tttagtgag gcaacttgc catacatgc cgatttggc 
agcgactgt tctcaattc gctacggag tcacgcgac 
tgatccgta cgcctctaa ttggctgga aagactgag 
gaaattgaa aaatttgag agagaaggt cgtacaaga 
gaacaataa gaggaaaga ggcgcagaa aggcttcag 
cgaggaaaa ggacatcgt ggaggattt taccgactt 
tacataatt ttttgttgc atttctatt accattacc 
caatatatt actatcgat tga

    If you use iBeetle-Base, please cite: Dönitz J et al.: Expanded and updated data and a query pipeline for iBeetle-Base,
    Nucleic Acids Res. 2018 Jan 4;46(D1):D831-D835. doi: 10.1093/nar/gkx984.

    The data is licensed under a Creative Commons Attribution 3.0 Unported License. (CC-BY) CC-BY