Status
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Gene information
General information
TC002876 Gene

The sequence from the iB fragment is matched against the genes from the official gene set. The matche(s) is/are visualizied in a genome browser.

NC_007418.3: 7596599..7603677
Sequence information
Transcripts / Proteins (1) Get mRNA sequence
Get CDS sequence
Get protein sequence
Ortholog information (from OrthoDB)

The information about the homolog genes in Drosophila is provided by OrthoDB http://www.orthodb.org/. The homologs are sorted according to their similarity score. For an orthology statement additional analysis are required.
The data basis for the orthologs is OrthoDB v9 containing OGS3 for Tribolium castaneum and 2015_04 (r6.07) for Drosophila melanogaster.

Closest fly homologs
    TC002876
    Gene ontology

    GO terms for Tribolium

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    There are no GO terms for Tribolium at the moment. You can help the community by providing some GO terms for this gene.


    GO terms for the homologous Drosophila genes


    Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term - use "graph views" to browse related terms ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.


    Gene
    {{ goGene }}
    The Tribolium gene the GO term is assigned to.
    GO ID *
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    The ID of the GO term you assign to the gene. Please enter only the ID of the GO term with proceeding 'GO:'. This information is mandatory.
    Evidence
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    The evidence code describes with which method the function or location, expressed by the GO term, was show for this gene. Please refer to this page for a definition of the evidence code and a decision tree.
    Reference *
    {{ blurReferenceResult }}
    The reference where the function or location is described for the gene. Please enter a PubMed ID. This information is mandatory.
    Quotation
    If you paste here the relevant section of the reference it is for us a great help to review your annotation. The quotation may be also be displayed to the users of iBeetle-Base.
    Name
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    Email
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    Publish name
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    * : mandatory fields
    For help on how to submit larger datasets or non experimental data please contact us.
    iBeetle screen iB_00461

    Attention! iBeetle is a first pass screen. Hence, the documented phenotypes need to be confirmed by independent experiments using non-overlapping dsRNA fragments! Phenotypes with a penetrance > 50% are frequently reproduced. See Schmitt-Engel et al. 2015 for details on reproducibility.

    iB sequence
    Phenotype after pupal injection
    Usually 10 injected animals

    Pupal injection procedure

    Day 0: 10 female pupae of the pBA19 strain (muscle enhancer trap line) were injected with dsRNA.

    3 days post injection (dpi): Hatch control: Pupal and adult lethality as well as metamorphosis defects (molting, eclosion) were documented. For mating, 4 males of the black strain were added.

    9 dpi: First egg-lay was collected and incubated for cuticle analysis. Adult lethality and egg production (reduced/ no egg-lay) was documented.

    11 dpi: Second egg-lay was collected and incubated for embryonic muscle analysis. Adult lethality and egg production (reduced/ no egg-lay) were documented.

    Note: The adult morphology was not analyzed systematically at 3/9/11 dpi. Only obvious phenotypes, visible without magnification, have been annotated.

    13 dpi: Egg productivity and Ovary analysis
    The percentage of hatched larvae was documented and not hatched larvae/ eggs were embedded for cuticle analysis (15 dpi). In case of a reduction of egg production, 4 injected females were dissected to analyze the gross morphology of the ovaries.

    14 dpi: Analysis of embryonic musculature and early embryonic development
    Offspring of the injected females (hatched and not hatched larvae/ eggs) were analysed for embryonic lethality and muscle defects.

    15 dpi: Analysis of larval instar 1 cuticle
    Offspring of injected females were analysed and cuticle phenotypes were annotated.

    22 dpi: Stink gland analysis
    Documentation of defects in abdominal and thoracic stink glands (colour, size, content) of the injected femals.

    Terms used in the pupal injection procedure

    larval pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    empty eggs
    Just empty shells are visible, no cuticle has been developed.
    strong defects
    L1 cuticle larvae which show severe defects. These strong defects are subdivided into three categories
    strongly fragmented (cuticle crumbs)
    No segments or appendages are identifiable, only residues of cuticle and bristles can be identified.
    cuticle remnants (with unidentifiable segments)
    Segments or parts of appendages are recognizable, but identity is not clear.
    cuticle remnants (with some identifiable segments)
    At least one segment or appendage is clearly regonizable.
    number of eggs on slide
    affected embryos usually (not always) do not hatch. Only the not hatched were used for cuticle analysis.
    For the embryonic muscle analysis the hatched as well as the not hatched were analysed.
    total number of affected eggs/embryos/larvae
    Summary of all different phenotypes/ phenotypic series which were annotated.
    inside-out
    The L1 larva shows a partial or complete inversion., e.g. bristles, appendages or parts of the abdominal segments are inverted into the interior of the cuticle.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    Please see the help page for more information
    Metamorphosis and survival

    Lethality 11 days after pupal injection: 60.0% (includes death as pupa, adult)

    pupa eclosion not fulfilled (died as pupa) - Number of animals showing the phenotype: 1 (3 dpi)
    Days post injection


    adult lethality - Number of animals showing the phenotype: 5 (11 dpi)
    Days post injection


    Fertility
    eggs lost during procedure: potentially due to defects in egg-shells egg-morphology or egg-size, (14 dpi)
    Phenotype after larval injection
    Usually 10 injected animals

    Larval injection procedure

    Day 0: 10 female L5-6 larvae of the D17Xhom strain (females express RFP in the eyes and in the CNS; pupae express GFP in the thorax) were injected with dsRNA.

    11 days post injection (dpi): Pupal morphology Documentation of larval/ pupal death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of pupal head and appendages, pupal thorax, pupal thoracic musculature, pupal legs, pupal wings, pupal abdomen and pupal genital lobes.

    16 dpi: Adult morphology Documentation of larval/ pupal and adult death and defects of metamorphosis (eclosion, delayed development). Screening for alterations of adult head and appendages, adult thorax, adult elytra and hindwings, adult legs and cuticle properties. For mating 4 males of the black strain were added.

    19 dpi: Sieving and egg-lay Documentation of adult lethality and enduring metamorphosis defects.

    22 dpi: Ovary analysis (Fertility) In case of a reduction of egg production 4 females were dissected and the gross morphology of the ovaries were analysed.

    41 dpi: Fertility and stink gland analysis Documentation of defects in abdominal and thoracic stink glands development (colour, size, content) of the injected females. Check for fertility of injected larvae (no or decreased offspring).

    Terms used in the larval injection procedure

    pupal/ adult pantagmatic defects
    At least two tagmata (head, thorax, abdomen or terminus) show similar/ comparable defects.
    pupal molt not fulfilled
    The hatching from the larva to the pupa is interrupted. Either it dies as prepupa or the phenotype shows larval as well as pupal features.
    eclosion not fulfilled
    The emergence of the adult from the pupa stage is interrupted. This phenotype shows pupal as well as adult features.
    starved
    Dissected females show a strong resorption of fatbody predominately in the abdomen and the oogenesis is blocked. These are considered as eventually lethal phenotypes and the blocked oogenesis probably a secondary defect due to starvation.
    Metamorphosis and survival

    Lethalities 11 days after larval injection: 60.0% (includes death as larva, prepupa, pupa)
    Lethalities 22 days after larval injection: 100.0% (includes death as larva, prepupa, pupa, adult)

    larva lethality early (L5/6) - Number of animals showing the phenotype: 6 (11 dpi)
    Days post injection


    pupal molt delayed (still larva) - Number of animals showing the phenotype: 4 (11 dpi)
    Days post injection


    larva lethality late (L7) - Number of animals showing the phenotype: 1 (16 dpi)
    Days post injection


    pupal molt delayed (still larva) - Number of animals showing the phenotype: 3 (16 dpi)
    Days post injection


    remarks: later than schedule, pupal molt not fulfilled (died as L7 or prepupa) - Number of animals showing the phenotype: 4 (19 dpi)
    Days post injection


    Pupal morphology
    remarks: later than schedule,
    Adult morphology
    remarks: later than schedule,
    RNAi sequence
    Primers
    Left: Right:
    Protein sequence
    • >TC002876 RA
      MSTSLSEQL KRLALPQTS LLQRDKKRP SLLFDPKEA 
      AGLKRETVY QIGLDGLEE LITKNPVFE QFKSNIFHI 
      TSKKFERAV QSADANKKL DKVIRKFLL QLSPYFLLN 
      CAHKALEWL INRYNIHEF NRDDLLMLI MPYHESNIF 
      VRVVQLMKF KDENDSWFF LKSIQKTGV HLTKQSLLN 
      KASSDVYFL KFVAKFISL LVKQFEKPS LLTVAFNFY 
      CTVFVGAIE YSSELNEAQ ITQMLPALL KGLNSDIPD 
      FCAASYVIL GRLVMKTPL TDAILDKFV EKVSVSKVE 
      TLKTESVLT LLILCQSQT HYTQLPESA CYSLIGKNW 
      LPKVLQDLS NGNCFVTPF LKVLVKTCL YGAVKLDLE 
      EYRAFMKTL LAAIKFDDA FMEIFLSLL LDRTKTKKP 
      YSEHLQKWL TEIIETLER QYPDQFDKE VYKILSTTQ 
      QGKVIKRRK SLQKILTET MNIRCKFDV LAKLYHPNV 
      TYRKEAIKY LVNNYDSLR DREKEMIKS SFIDRLNDD 
      SVEVVHETL NLIKNISVL KTDALKDVL TKLAYKCQS 
      DLKTWGSVS TEIVLMLCE QSEANDWET FVAVLPYLL 
      PNSENQLSA AQTIAESSF CRKNCLLKK INAKGEDCA 
      QFCNSVFDS MRNNNKELV NDFIACIHK TTDRSVLSK 
      YLIILILSI ILPENSSIE SNITIVKIF IEFIENCEI 
      KYEKGNAFM QKHISVARA GQFHIEGFL LCLKNVIVK 
      TLKPTVELG RVDLHEDTD FNQYFTLLA TTLLKNKSN 
      HKKYVHVFI NYFCKTFRS KIEFLLNLV NSGKSQDLE 
      FVTESVSLI AKLLSSVKD SNEMSSLLE SDIFIPQLL 
      ALLLHKSED VKQKSFRIV EILTEVKND TFGHLFREL 
      LDQREEIVV DNDQLPLIM FNYLSPSAV KDTKVSGNA 
      STLKTLLIK TSCGKYPVY LKSKMLELL SHINTIEIF 
      EETSHDCLH LLKTQSKNL DEVKSSIVV RNLQRCQPT 
      IAGNIAVGT SIWTLIETC LKDSDFTLT VDSKPEFAT 
      VLLLKQFDR EFFAQLDAK VETKLLDLI VETATLTKN 
      PDVLPAVRH TIKVIELDA KLILSHFVK MRDVQSPKL 
      DPNKLKRRI SVVPTVDIL DTLDWRKGL TALEFIQDK 
      KKLTNIEVL FPVLFEILK KCLDFDEQA AVEYPKQLI 
      LLSILYLGE KIDRDSIGE TTFNMELIV QCIRASQNP 
      QTHYCALLV LAFSAELFP SQVLHHIMA IFTFMGSSV 
      LRHEDAYSF QIITRIIDT VIPILVKDN NPETIARVL 
      RVFVDALLD VPEHRRMPI YGHLLTKLQ VKDNLYIFL 
      LLIFESHVN HSHRDKNKE DDMKRLEIA ASVCREFSP 
      EIVIQNCIN LMKYLKELP DEVDSDNTS SPFDIHYKT 
      PKQFRHYKY TLIIFTARL LSSKEFVFQ VASLKNDEL 
      LDLQQLYKD MIINILTYI YRISKIADK NANTQHAKY 
      WKVILHLSY DILDSVNAL LTPQMFLLV VKGLMLHNF 
      STIRRRSME LLNSKLQNN PSFFDDCTS EQIYSLIPP 
      LISIIKNVE EAQSESDDE LIVQTALLS LKLLTKFLV 
      SDYHEKLAE ILDFVTDLA KSGKVQNNV LASVLLCLA 
      ELCTNLRAH AIPSLPNFM PAILRILKQ QKSQESSSL 
      LLLSSVTTV QKIVETLPL FLSPYLEKL LYELSLLAS 
      NVAEEERLQ PVVNKLSNL KQQIGTSIP PRVLIPVLG 
      QSYDRLITK QAFSAVGFL LDTLAENLN HLNGSEIGA 
      NLPELTSFF LNALQFRTD QDTTFEQAN EVEAQIVKA 
      LTKLILKLS ESTFKPLYY KLFDWAARH EQKTERLIT 
      FYALSSGIA EALKSLFVL FAGHFLNNA AQILDSCNV 
      TKTDALYFD DEKKNVLLL ENVLKTLHS VFLYDSHKF 
      VNKDRFEVL MQPLVDQLE NTLGGVGGL ERRNGELVT 
      PVIVQFAVA TADDSLWKQ LNYQILLKM KHNSPEIRL 
      ISLNCLKEM VTKLGVDYL PLLPETIPV LAELLEDEE 
      ESVEKACRK AVQEMEKIL GEPIEKYFK M
    CDS sequence
    • >TC002876 RA
      atgagcacc tcactgagc gagcaactc aagcgcctg 
      gctttgccc caaacctcg ctgttacaa agggacaag 
      aaacgccca tctttgctc ttcgaccct aaggaagcg 
      gctggtttg aaacgtgag accgtttac caaatcggt 
      cttgacggt ttagaagaa ttgatcacg aaaaaccca 
      gtctttgag cagtttaaa agcaacatt tttcacata 
      acttcaaaa aaatttgag cgcgcggtg caatccgct 
      gacgcaaac aaaaagttg gataaagtg attaggaaa 
      tttctgctg caattgtcg ccttatttt ttgctgaac 
      tgtgcacat aaggcgctt gaatggctc ataaacaga 
      tacaacatt catgaattt aacagagac gatttgctt 
      atgcttata atgccgtat cacgagtcg aatattttc 
      gttagagtg gtgcagttg atgaaattc aaggatgag 
      aatgacagt tggttcttt ttgaagtcg attcagaaa 
      actggggtt catctcact aaacaaagc ctactaaac 
      aaggcatca agtgatgtt tatttccta aaatttgtg 
      gccaaattc atctctctg ctcgtgaag caatttgaa 
      aaaccctcg ttactcacc gtcgctttc aacttttat 
      tgcaccgtt ttcgtgggg gctattgaa tattcctcc 
      gagttaaat gaagctcag atcactcag atgctacca 
      gcgctcctc aaaggccta aattcggac attccggat 
      ttttgcgcc gcttcgtac gttattctg ggacgactt 
      gtaatgaaa acgccgcta actgatgca attttggac 
      aaattcgtc gaaaaagta tccgtgtcg aaagttgaa 
      actttgaaa actgaatca gttttgact cttttgatt 
      ctttgccaa tctcagact cattacact cagttaccg 
      gaatcggct tgctatagt ttgattggg aaaaattgg 
      ttaccgaaa gtcttgcaa gatttgagc aacggaaat 
      tgtttcgtt accccattt ttgaaggtt ttggtcaag 
      acgtgcttg tatggggct gtcaaactg gacctggag 
      gagtatcgc gcttttatg aagactctt ctagcggcg 
      attaaattc gacgacgct ttcatggaa atattttta 
      agtcttctt ctcgaccgt accaagacc aagaaaccc 
      tactcggaa cacctccaa aaatggcta acggaaata 
      atcgaaacg ctcgaacgc caatacccc gaccaattc 
      gataaagaa gtctacaaa atcctctcg acaacgcaa 
      caaggcaaa gtgatcaag cgacgaaaa tcgcttcaa 
      aaaatcctc accgaaaca atgaacatt cggtgcaag 
      ttcgacgtt ttggccaag ttatatcac cccaacgtc 
      acataccga aaagaagcc atcaaatat cttgtcaat 
      aattatgac tctctccgc gaccgtgaa aaagaaatg 
      atcaaaagc tcgttcatt gatcgcctg aacgacgac 
      agcgtggaa gtcgttcat gaaacacta aacctgatc 
      aaaaatata tctgttctg aagacagac gcgctgaag 
      gacgttttg accaaactg gcctacaag tgccagagc 
      gatttgaag acttggggg tccgtctcg accgaaatt 
      gtgctcatg ttgtgcgag caaagcgag gcaaacgac 
      tgggaaacg ttcgtagcc gtgcttccc tacttatta 
      ccaaactct gaaaatcag ttaagtgca gcacaaaca 
      attgccgaa agttcgttc tgtcgtaaa aattgcttg 
      ctgaagaag attaacgcc aaaggtgag gattgtgcc 
      cagttttgt aacagcgtt tttgactca atgcggaac 
      aacaacaaa gaactggtc aacgacttt atcgcctgt 
      attcacaaa acgacagat cgttccgta ctcagcaaa 
      tatctgata attcttatt ctgagcatc atcctacct 
      gaaaatagc tcaattgag agcaacatc acaatcgtc 
      aaaatcttt atcgagttt atcgaaaat tgtgagatt 
      aaatatgaa aaagggaac gcttttatg caaaaacac 
      atcagtgtg gctcgcgcc ggccagttc cacatcgaa 
      gggtttcta ctgtgtttg aaaaacgta attgtgaag 
      acacttaaa cccacggtt gagttgggc cgagttgac 
      ttacatgag gacactgat tttaatcaa tactttact 
      ttacttgcc accacttta ctcaaaaac aagtcaaac 
      cacaaaaag tacgtccac gtttttatt aactacttc 
      tgcaaaacg ttccgaagc aaaatagag tttttatta 
      aacttggtc aacagtggg aagagccag gatttagag 
      ttcgtgacc gaaagtgtg tcactaatt gcgaaattg 
      ctgtccagt gtcaaggac agcaacgaa atgagttcg 
      cttctcgag agtgatatt tttatcccc caacttctg 
      gccttgttg ttacacaaa tcggaagac gtcaagcaa 
      aaaagtttc cgaattgtt gaaatctta accgaagtg 
      aagaacgat acttttggc cacctcttt agggagttg 
      ttggaccaa agggaggag attgttgtt gacaatgac 
      cagttgcca ctcatcatg tttaactac ttgtcacct 
      tctgcagtc aaagacacg aaagtttct ggcaatgca 
      tcaacgctt aaaacacta ttaattaaa acaagctgt 
      ggcaaatac ccggtctat ctgaaatcg aaaatgttg 
      gagctccta tcccacatt aacacgatc gaaatcttc 
      gaggaaacg tcgcacgat tgcttgcac ttgctcaaa 
      acccagagc aagaatttg gacgaagtc aagtcatcg 
      atagtcgtc cgaaacttg caacgttgc cagcccaca 
      atcgccgga aatatcgca gtggggacg tccatctgg 
      actttgatt gagacgtgt ctcaaagac tcggacttc 
      actctcact gttgactcc aaaccggag tttgcaaca 
      gtattactt ttgaagcag ttcgatcgc gagtttttc 
      gcccaactg gacgcgaaa gtcgagacg aagctcctc 
      gacttgatc gtcgaaacg gccactctg accaaaaac 
      ccggacgtt ctgccggcc gttcggcac acgatcaag 
      gtgatagaa ctggacgcg aagctaatt ctgagccat 
      ttcgtcaaa atgcgagac gtgcagtcg cccaaactc 
      gaccccaac aagctaaaa cggcggatc agtgttgtg 
      cccactgtg gatattttg gacactttg gactggcgc 
      aagggcctg acggcgctc gagtttatc caagacaag 
      aagaaactg accaatatt gaggtcctg ttccccgtg 
      ttgttcgag attttgaag aagtgtctc gattttgac 
      gaacaggcg gccgtggag taccccaag cagttgatc 
      ctcttgtcg attctctac ctgggggag aaaatcgat 
      agggatagt ataggagag actacgttc aacatggag 
      ttgattgtt cagtgtatc agggcgtcg caaaacccg 
      cagacccac tattgcgcc cttttggtg ctggccttt 
      tcggcggag ttgttccct tcgcaagtt ttgcaccac 
      ataatggcc attttcacg tttatgggc tcgtctgtt 
      ctgagacac gaggatgcg tacagtttt cagatcatt 
      acgaggatt atcgatact gtgataccg attctagtc 
      aaggataat aatcctgaa actatagcc agggttttg 
      agggttttt gtggacgcc cttctggac gttcccgag 
      caccggagg atgccgatt tatgggcac ttgctgacg 
      aagttgcaa gtcaaggac aatctttac atatttttg 
      ttgctgatt ttcgagtca cacgttaat cacagccac 
      agggacaaa aacaaagag gacgatatg aagcggctc 
      gaaatcgca gcgagtgtt tgccgcgag ttttcgcca 
      gaaatcgta atccagaat tgtatcaac ttgatgaaa 
      tacttgaag gagttaccc gacgaagtc gacagtgac 
      aacacgagt tcgcctttt gatatccat tataaaacg 
      ccaaagcaa ttccgacat tacaaatac actttaatt 
      attttcacc gcgaggtta ctgtcgtcc aaagagttt 
      gttttccaa gtggcttcg ctgaaaaac gacgaactg 
      ctcgacttg cagcagctg tacaaagac atgattata 
      aacatcctg acgtacatt taccgcatt tccaaaatt 
      gcggacaag aacgcaaac acgcaacac gccaagtac 
      tggaaggtc atcctccac ttgagttac gatatcctg 
      gacagcgtc aacgcactg ttaaccccc cagatgttc 
      ttgttggtg gtcaaaggc ctgatgctg cacaacttc 
      agcacgatt cggaggcgc agcatggag ttgttgaac 
      tccaaactg cagaacaac ccttcgttt ttcgacgac 
      tgcacgtcg gagcaaatc tactcgtta atcccgccc 
      ctcatttca atcattaag aacgtggaa gaggcgcag 
      agcgagagc gacgacgag ctgatcgtg caaactgcg 
      ctcctctcc ttgaagctt ctgaccaag ttcttagtc 
      tcggactac cacgagaaa ctggccgag attctcgac 
      ttcgtgacc gatttggcc aaaagtggc aaagtgcaa 
      aacaacgtc cttgcctca gttttgctg tgcttggcc 
      gagctttgc acgaacttg cgggcacat gccatcccc 
      agcctcccg aacttcatg cccgcgatt ttgaggatt 
      ttgaagcaa cagaagagt caagaatcg tcgagtttg 
      ctcctcttg agttcggtc accactgtg caaaagatt 
      gtcgaaacg ctcccactt ttcctcagc ccgtatctc 
      gagaaatta ttgtatgag ctgtcgcta cttgcgagt 
      aacgtagcc gaggaggaa cgcctccaa cccgttgtg 
      aataaacta tcaaacttg aagcaacaa atcgggact 
      tccatcccc ccacgggtg ttaataccg gttttgggg 
      caaagctac gaccgcctg atcacgaaa caggcgttt 
      agcgctgtg ggatttctg ctcgacact ttggccgag 
      aatttgaac cacttgaac gggtccgaa atcggcgcg 
      aatttgccc gaactgacc agctttttc ctgaatgcg 
      ctccagttc aggacggat caagacacg acgttcgaa 
      caggccaac gaagtggag gcgcaaatc gtcaaagct 
      ttgactaaa ctgatcttg aaactgtcg gaaagtacg 
      ttcaagccc ttgtattac aaactgttt gattgggcg 
      gcgcgacac gagcagaaa actgaacga cttatcacg 
      ttctatgcg ctgtctagc gggattgcc gaagctttg 
      aaaagttta tttgtgctt ttcgctggc catttcctc 
      aacaatgcg gcccagatt ctggattcg tgcaacgtc 
      actaaaacc gacgctctc tatttcgac gatgagaag 
      aagaatgtt ctcttgttg gagaatgtt ttgaagacg 
      cttcattcc gtgtttctg tacgatagt cacaagttt 
      gttaacaag gaccggttt gaggttttg atgcagccg 
      ctggtggat cagttggaa aacacctta gggggtgtt 
      gggggcttg gaaaggcgg aatggcgag ttggtgacg 
      ccggtgatt gtgcagttt gcggtggca acggctgat 
      gattcgttg tggaagcag cttaattac cagattttg 
      ctgaaaatg aagcacaat tcgcctgag attaggctg 
      atttcgttg aattgtttg aaggagatg gtgacgaag 
      ctgggggtt gattatttg cccttgtta ccggagacg 
      atcccagtg ttggccgaa ttgttggaa gatgaggag 
      gaaagtgtg gagaaggcg tgcaggaag gcggtccaa 
      gagatggag aagatttta ggggagcca attgaaaag 
      tatttcaaa atgtaa
    mRNA sequence
    • >TC002876 RA
      tcataacca cagtttttc agcgtgccc cagttgtca 
      cgtgtaatg taatttctg gcgttgttt ttgtttaca 
      ggcgccggt tttggataa aataaagat gagcacctc 
      actgagcga gcaactcaa gcgcctggc tttgcccca 
      aacctcgct gttacaaag ggacaagaa acgcccatc 
      tttgctctt cgaccctaa ggaagcggc tggtttgaa 
      acgtgagac cgtttacca aatcggtct tgacggttt 
      agaagaatt gatcacgaa aaacccagt ctttgagca 
      gtttaaaag caacatttt tcacataac ttcaaaaaa 
      atttgagcg cgcggtgca atccgctga cgcaaacaa 
      aaagttgga taaagtgat taggaaatt tctgctgca 
      attgtcgcc ttatttttt gctgaactg tgcacataa 
      ggcgcttga atggctcat aaacagata caacattca 
      tgaatttaa cagagacga tttgcttat gcttataat 
      gccgtatca cgagtcgaa tattttcgt tagagtggt 
      gcagttgat gaaattcaa ggatgagaa tgacagttg 
      gttcttttt gaagtcgat tcagaaaac tggggttca 
      tctcactaa acaaagcct actaaacaa ggcatcaag 
      tgatgttta tttcctaaa atttgtggc caaattcat 
      ctctctgct cgtgaagca atttgaaaa accctcgtt 
      actcaccgt cgctttcaa cttttattg caccgtttt 
      cgtgggggc tattgaata ttcctccga gttaaatga 
      agctcagat cactcagat gctaccagc gctcctcaa 
      aggcctaaa ttcggacat tccggattt ttgcgccgc 
      ttcgtacgt tattctggg acgacttgt aatgaaaac 
      gccgctaac tgatgcaat tttggacaa attcgtcga 
      aaaagtatc cgtgtcgaa agttgaaac tttgaaaac 
      tgaatcagt tttgactct tttgattct ttgccaatc 
      tcagactca ttacactca gttaccgga atcggcttg 
      ctatagttt gattgggaa aaattggtt accgaaagt 
      cttgcaaga tttgagcaa cggaaattg tttcgttac 
      cccattttt gaaggtttt ggtcaagac gtgcttgta 
      tggggctgt caaactgga cctggagga gtatcgcgc 
      ttttatgaa gactcttct agcggcgat taaattcga 
      cgacgcttt catggaaat atttttaag tcttcttct 
      cgaccgtac caagaccaa gaaacccta ctcggaaca 
      cctccaaaa atggctaac ggaaataat cgaaacgct 
      cgaacgcca ataccccga ccaattcga taaagaagt 
      ctacaaaat cctctcgac aacgcaaca aggcaaagt 
      gatcaagcg acgaaaatc gcttcaaaa aatcctcac 
      cgaaacaat gaacattcg gtgcaagtt cgacgtttt 
      ggccaagtt atatcaccc caacgtcac ataccgaaa 
      agaagccat caaatatct tgtcaataa ttatgactc 
      tctccgcga ccgtgaaaa agaaatgat caaaagctc 
      gttcattga tcgcctgaa cgacgacag cgtggaagt 
      cgttcatga aacactaaa cctgatcaa aaatatatc 
      tgttctgaa gacagacgc gctgaagga cgttttgac 
      caaactggc ctacaagtg ccagagcga tttgaagac 
      ttgggggtc cgtctcgac cgaaattgt gctcatgtt 
      gtgcgagca aagcgaggc aaacgactg ggaaacgtt 
      cgtagccgt gcttcccta cttattacc aaactctga 
      aaatcagtt aagtgcagc acaaacaat tgccgaaag 
      ttcgttctg tcgtaaaaa ttgcttgct gaagaagat 
      taacgccaa aggtgagga ttgtgccca gttttgtaa 
      cagcgtttt tgactcaat gcggaacaa caacaaaga 
      actggtcaa cgactttat cgcctgtat tcacaaaac 
      gacagatcg ttccgtact cagcaaata tctgataat 
      tcttattct gagcatcat cctacctga aaatagctc 
      aattgagag caacatcac aatcgtcaa aatctttat 
      cgagtttat cgaaaattg tgagattaa atatgaaaa 
      agggaacgc ttttatgca aaaacacat cagtgtggc 
      tcgcgccgg ccagttcca catcgaagg gtttctact 
      gtgtttgaa aaacgtaat tgtgaagac acttaaacc 
      cacggttga gttgggccg agttgactt acatgagga 
      cactgattt taatcaata ctttacttt acttgccac 
      cactttact caaaaacaa gtcaaacca caaaaagta 
      cgtccacgt ttttattaa ctacttctg caaaacgtt 
      ccgaagcaa aatagagtt tttattaaa cttggtcaa 
      cagtgggaa gagccagga tttagagtt cgtgaccga 
      aagtgtgtc actaattgc gaaattgct gtccagtgt 
      caaggacag caacgaaat gagttcgct tctcgagag 
      tgatatttt tatccccca acttctggc cttgttgtt 
      acacaaatc ggaagacgt caagcaaaa aagtttccg 
      aattgttga aatcttaac cgaagtgaa gaacgatac 
      ttttggcca cctctttag ggagttgtt ggaccaaag 
      ggaggagat tgttgttga caatgacca gttgccact 
      catcatgtt taactactt gtcaccttc tgcagtcaa 
      agacacgaa agtttctgg caatgcatc aacgcttaa 
      aacactatt aattaaaac aagctgtgg caaataccc 
      ggtctatct gaaatcgaa aatgttgga gctcctatc 
      ccacattaa cacgatcga aatcttcga ggaaacgtc 
      gcacgattg cttgcactt gctcaaaac ccagagcaa 
      gaatttgga cgaagtcaa gtcatcgat agtcgtccg 
      aaacttgca acgttgcca gcccacaat cgccggaaa 
      tatcgcagt ggggacgtc catctggac tttgattga 
      gacgtgtct caaagactc ggacttcac tctcactgt 
      tgactccaa accggagtt tgcaacagt attactttt 
      gaagcagtt cgatcgcga gtttttcgc ccaactgga 
      cgcgaaagt cgagacgaa gctcctcga cttgatcgt 
      cgaaacggc cactctgac caaaaaccc ggacgttct 
      gccggccgt tcggcacac gatcaaggt gatagaact 
      ggacgcgaa gctaattct gagccattt cgtcaaaat 
      gcgagacgt gcagtcgcc caaactcga ccccaacaa 
      gctaaaacg gcggatcag tgttgtgcc cactgtgga 
      tattttgga cactttgga ctggcgcaa gggcctgac 
      ggcgctcga gtttatcca agacaagaa gaaactgac 
      caatattga ggtcctgtt ccccgtgtt gttcgagat 
      tttgaagaa gtgtctcga ttttgacga acaggcggc 
      cgtggagta ccccaagca gttgatcct cttgtcgat 
      tctctacct gggggagaa aatcgatag ggatagtat 
      aggagagac tacgttcaa catggagtt gattgttca 
      gtgtatcag ggcgtcgca aaacccgca gacccacta 
      ttgcgccct tttggtgct ggccttttc ggcggagtt 
      gttcccttc gcaagtttt gcaccacat aatggccat 
      tttcacgtt tatgggctc gtctgttct gagacacga 
      ggatgcgta cagttttca gatcattac gaggattat 
      cgatactgt gataccgat tctagtcaa ggataataa 
      tcctgaaac tatagccag ggttttgag ggtttttgt 
      ggacgccct tctggacgt tcccgagca ccggaggat 
      gccgattta tgggcactt gctgacgaa gttgcaagt 
      caaggacaa tctttacat atttttgtt gctgatttt 
      cgagtcaca cgttaatca cagccacag ggacaaaaa 
      caaagagga cgatatgaa gcggctcga aatcgcagc 
      gagtgtttg ccgcgagtt ttcgccaga aatcgtaat 
      ccagaattg tatcaactt gatgaaata cttgaagga 
      gttacccga cgaagtcga cagtgacaa cacgagttc 
      gccttttga tatccatta taaaacgcc aaagcaatt 
      ccgacatta caaatacac tttaattat tttcaccgc 
      gaggttact gtcgtccaa agagtttgt tttccaagt 
      ggcttcgct gaaaaacga cgaactgct cgacttgca 
      gcagctgta caaagacat gattataaa catcctgac 
      gtacattta ccgcatttc caaaattgc ggacaagaa 
      cgcaaacac gcaacacgc caagtactg gaaggtcat 
      cctccactt gagttacga tatcctgga cagcgtcaa 
      cgcactgtt aacccccca gatgttctt gttggtggt 
      caaaggcct gatgctgca caacttcag cacgattcg 
      gaggcgcag catggagtt gttgaactc caaactgca 
      gaacaaccc ttcgttttt cgacgactg cacgtcgga 
      gcaaatcta ctcgttaat cccgcccct catttcaat 
      cattaagaa cgtggaaga ggcgcagag cgagagcga 
      cgacgagct gatcgtgca aactgcgct cctctcctt 
      gaagcttct gaccaagtt cttagtctc ggactacca 
      cgagaaact ggccgagat tctcgactt cgtgaccga 
      tttggccaa aagtggcaa agtgcaaaa caacgtcct 
      tgcctcagt tttgctgtg cttggccga gctttgcac 
      gaacttgcg ggcacatgc catccccag cctcccgaa 
      cttcatgcc cgcgatttt gaggatttt gaagcaaca 
      gaagagtca agaatcgtc gagtttgct cctcttgag 
      ttcggtcac cactgtgca aaagattgt cgaaacgct 
      cccactttt cctcagccc gtatctcga gaaattatt 
      gtatgagct gtcgctact tgcgagtaa cgtagccga 
      ggaggaacg cctccaacc cgttgtgaa taaactatc 
      aaacttgaa gcaacaaat cgggacttc catcccccc 
      acgggtgtt aataccggt tttggggca aagctacga 
      ccgcctgat cacgaaaca ggcgtttag cgctgtggg 
      atttctgct cgacacttt ggccgagaa tttgaacca 
      cttgaacgg gtccgaaat cggcgcgaa tttgcccga 
      actgaccag ctttttcct gaatgcgct ccagttcag 
      gacggatca agacacgac gttcgaaca ggccaacga 
      agtggaggc gcaaatcgt caaagcttt gactaaact 
      gatcttgaa actgtcgga aagtacgtt caagccctt 
      gtattacaa actgtttga ttgggcggc gcgacacga 
      gcagaaaac tgaacgact tatcacgtt ctatgcgct 
      gtctagcgg gattgccga agctttgaa aagtttatt 
      tgtgctttt cgctggcca tttcctcaa caatgcggc 
      ccagattct ggattcgtg caacgtcac taaaaccga 
      cgctctcta tttcgacga tgagaagaa gaatgttct 
      cttgttgga gaatgtttt gaagacgct tcattccgt 
      gtttctgta cgatagtca caagtttgt taacaagga 
      ccggtttga ggttttgat gcagccgct ggtggatca 
      gttggaaaa caccttagg gggtgttgg gggcttgga 
      aaggcggaa tggcgagtt ggtgacgcc ggtgattgt 
      gcagtttgc ggtggcaac ggctgatga ttcgttgtg 
      gaagcagct taattacca gattttgct gaaaatgaa 
      gcacaattc gcctgagat taggctgat ttcgttgaa 
      ttgtttgaa ggagatggt gacgaagct gggggttga 
      ttatttgcc cttgttacc ggagacgat cccagtgtt 
      ggccgaatt gttggaaga tgaggagga aagtgtgga 
      gaaggcgtg caggaaggc ggtccaaga gatggagaa 
      gattttagg ggagccaat tgaaaagta tttcaaaat 
      gtaaataga attttaatg atttaagaa ggcaataaa 
      cggttttta attaataca ttgtttatt ttgta
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