Gene identifier: TC000361
Genomic location: NC_007417.3:12453557..12474866
View gene expression at BeetleAtlas 
View orthologs at OrthoDB 
Gene IDAlgorithmsGene SymbolGene NameShow GO Terms
FBgn0025360Eggnog6, OrthoFinderOptix
FBgn0025360
GO:0048036 - central complex development
EXP
REVIEWED

we demonstrate that Tc-six3/optix is the first gene known to be required for the embryonic formation of the central complex, a midline-spanning brain part connected to the neuroendocrine pars intercerebralis.
PMID:22216011
GO:0045995 - regulation of embryonic development
EXP
REVIEWED

we show that Tc-six3/optix acts upstream of Tc-wingless, Tc-orthodenticle1, and Tc-eyeless to control anterior median development. Finally, we demonstrate that Tc-six3/optix is the first gene known to be required for the embryonic formation of the central complex, a midline-spanning brain part connected to the neuroendocrine pars intercerebralis.
PMID:22216011
Assign a GO term to this Tribolium gene by filling in the fields. Repeat to add several GO terms. Search AmiGO for the correct GO ID. Use only the most specific term ("child terms" are more specific; the more general "parent" terms will be automatically linked). Only information based on Tribolium data should be entered - do not define terms just based on Drosophila knowledge. We will review this information and submit the annotation to the Gene Ontology consortium.
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protein
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Authors: Posnien et al.Journal: PLoS geneticsYear: 2011
Authors: Steinmetz et al.Journal: EvoDevoYear: 2010
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*dsRNA:
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Lethalities 11 days after pupal injection: 80% (includes death as pupa, adult)
adult lethality
1 animal
day 11
adult lethality
2 animals
day 9
eclosion not fulfilled (with pupal and adult features)
5 animals
day 3
larval musculature pattern irregular
30%
day 14
embryo/egg with muscle fluorescence/pattern, but not hatched (pot. late embryonic lethality)
80%
day 14
affected eggs/embryos/larvae
80%
day 14
head cuticle ventral structure irregular
50%
day 15
head capsule potentially size decreased
50%
day 15
maxilla cuticle proximal irregular
50%
day 15
maxilla potentially orientation irregular
50%
day 15
labrum not present
100%
day 15
affected eggs/embryos/larvae
100%
day 15
larva number hatched none (< 10 %)
day 13
adult lethality
1 animal
day 22
Lethalities 11 days after pupal injection: 40% (includes death as pupa, adult)
adult lethality
1 animal
day 9
eclosion not fulfilled (with pupal and adult features)
3 animals
day 3
embryo/egg with muscle fluorescence/pattern, but not hatched (pot. late embryonic lethality)
100%
day 14
affected eggs/embryos/larvae
100%
day 14
labrum not present
100%
day 15
vertex vertex triplet anterior not present
80%
day 15
gena bristle number increased
50%
day 15
affected eggs/embryos/larvae
100%
day 15
larva number hatched none (< 10 %)
day 13